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[193635_s_at] 1-acyl-SN-glycerol-3-phophate acyltransferase

Description T06E8.1 /REP_DB=WormBase Gene ID /WP=CE06378 /TR=SW:Q22267 /GB=CAA98276.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=1-acyl-SN-glycerol-3-phophate acyltransferase
Cluster 6grp_highest_10_10 > 87      6grp_high1_10_10 > 87      4grp_highest_8_8 > 38      4grp_high_8_8 > 03      6grp_highest_nonorm > 95      6grp_total > 78      4grp_total > 05      6grp_highest_sub > Da      6grp_cgc > 49      6grp_high1_sub > In      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 746
1 2 3 4 range
A 773.7
(-0.1)
P
610.4
(-1.8)
P
501.5
(-3)
P
1066.7
(3)
P
565
B 799.3
(-0.6)
P
532.3
(-2.8)
P
508.4
(-3)
P
1247.2
(3)
P
739
C 813.8
(-0.2)
P
536.1
(-3)
P
576.5
(-2.6)
P
1124.4
(3)
P
588
avr 795.6
(-0.4)
559.6
(-2.7)
528.8
(-3)
1146.1
(3)
617

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 613
1 2 3 4 5 6 range
A 663.2
(-1)
P
514
(-3)
P
676.6
(-0.8)
P
617.5
(-1.6)
P
775.8
(0.6)
P
952.8
(3)
P
439
B 667.5
(-1.7)
P
568.7
(-3)
P
600.2
(-2.6)
P
586.8
(-2.8)
P
807.8
(0.1)
P
1038.8
(3)
P
470
C 545.9
(-2.7)
P
534.6
(-2.9)
P
519.7
(-3)
P
692.1
(-1.3)
P
656.8
(-1.6)
P
1127.3
(3)
P
608
avr 625.5
(-2)
539.1
(-3)
598.8
(-2.3)
632.1
(-1.9)
746.8
(-0.5)
1039.6
(3)
501
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 164
1 2 3 4 range
A 281.7
(3)
P
132.5
(-2.9)
P
131.1
(-3)
P
156.2
(-2)
P
151
B 254.9
(2.6)
P
131.5
(-2.4)
P
117.8
(-3)
P
265.8
(3)
P
148
C 269.4
(3)
P
154.1
(-3)
P
200.9
(-0.6)
P
189.6
(-1.2)
P
115
avr 268.7
(3)
139.4
(-3)
149.9
(-2.5)
203.9
(-0)
129

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 265
1 2 3 4 5 6 range
A 122.2
(-3)
P
182.8
(0.2)
P
147.4
(-1.6)
P
156.6
(-1.2)
P
234.1
(3)
P
232
(2.9)
P
112
B 232.3
(-0.9)
P
189.3
(-1.9)
P
145.7
(-3)
P
155.4
(-2.8)
P
328.2
(1.5)
P
387.4
(3)
P
242
C 202.4
(-1.3)
P
163.1
(-2.2)
P
132.3
(-3)
P
139.2
(-2.8)
P
212.5
(-1)
P
377.4
(3)
P
245
avr 185.6
(-1.6)
178.4
(-1.8)
141.8
(-3)
150.4
(-2.7)
258.3
(0.7)
332.3
(3)
191
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193635_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11856
Sequence Type Exemplar sequence
Representative Public ID T06E8.1 NCBI
Target Description T06E8.1 /REP_DB=WormBase Gene ID /WP=CE06378 /TR=SW:Q22267 /GB=CAA98276.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=1-acyl-SN-glycerol-3-phophate acyltransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073177(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_073177 NCBI Caenorhabditis elegans ACyLtransferase-like family member (acl-2) (acl-2) mRNA, complete cds. 11/11 None
SNAP00000037761 ENSEMBL cdna:SNAP chromosome:CEL140:V:10030941:10032118:-1 9/11 None
T06E8.1 ENSEMBL cdna:known chromosome:CEL140:V:10030795:10033675:-1 gene:T06E8.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000037764 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10030940-10033664(-) 100.0 100.0
Public Domain and Genome References
Gene Title 1-acyl-SN-glycerol-3-phophate acyltransferase
Gene Symbol acl-2
Ensembl T06E8.1
Entrez Gene 179398 Entrez gene
SwissProt Q22267 EMBL-EBI
WormBase CE06378 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.17275.1.S1_S_AT similar to 1-acylglycerol-3-phosphate O-acyltransferase 1 cfa
CANINE_2:CFAAFFX.2083.1.S1_AT similar to 1-acylglycerol-3-phosphate O-acyltransferase 1 cfa
DROSOPHILA_2:1641224_S_AT dm
DROSGENOME1:144962_AT dm
HG-U133_PLUS_2:215535_S_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-U133A_2:215535_S_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-FOCUS:215535_S_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-U133A:215535_S_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HUGENEFL:U56417_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
U133_X3P:HS.240534.2.S1_3P_S_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
U133_X3P:4890567C_3P_S_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
U133_X3P:32836_3P_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
U133_X3P:215535_3P_S_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-U133A:32836_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-U133A_2:32836_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-FOCUS:32836_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-U133_PLUS_2:32836_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
HG-U95AV2:32836_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) hs
MG-U74AV2:93720_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MG-U74BV2:111492_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MOE430A:1421024_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MOUSE430A_2:1421024_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MOUSE430_2:1421024_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MOE430A:1421025_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MOUSE430A_2:1421025_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MOUSE430_2:1421025_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) mm
MU19KSUBA:TC23872_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), mRNA (cDNA clone MGC:5841 IMAGE:3487719) mm
MU19KSUBC:TC39712_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), mRNA (cDNA clone MGC:5841 IMAGE:3487719) mm
RG-U34C:RC_AI072646_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 rn
RG-U34C:RC_AI232877_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 rn
RAE230A:1371748_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 rn
RAT230_2:1371748_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 rn
RAE230B:1392763_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 rn
RAT230_2:1392763_AT 1-acylglycerol-3-phosphate O-acyltransferase 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
8654 phospholipid biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3841 1-acylglycerol-3-phosphate O-acyltransferase activity inferred from electronic annotation QuickGO AmiGO
8415 acyltransferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98276 Hypothetical protein T06E8.1 [Caenorhabditis elegans] ref|NP_505578.1| ACyLtransferase-like family member (acl-2) [Caenorhabditis elegans] sp|Q22267|PLC2_CAEEL Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase T06E8.1 (1-AGP acyltransferase) (1-AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) 1.0E-157
blast CAE61082 Hypothetical protein CBG04832 [Caenorhabditis briggsae] 1.0E-131
blast CAA98276 Hypothetical protein T06E8.1 [Caenorhabditis elegans] ref|NP_505578.1| ACyLtransferase-like family member (acl-2) [Caenorhabditis elegans] sp|Q22267|PLC2_CAEEL Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase T06E8.1 (1-AGP acyltransferase) (1-AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) 3.0E-98
blast CAE61082 Hypothetical protein CBG04832 [Caenorhabditis briggsae] 3.0E-84
blast XP_781558 PREDICTED: similar to 1-acylglycerol-3-phosphate O-acyltransferase 1 [Strongylocentrotus purpuratus] 1.0E-45
blast XP_781558 PREDICTED: similar to 1-acylglycerol-3-phosphate O-acyltransferase 1 [Strongylocentrotus purpuratus] 4.0E-38
Protein Domains
Database ID Description E-Value
Pfam IPR002123 EMBL-EBI Phospholipid/glycerol acyltransferase 1.5E-50
Pfam IPR002123 EMBL-EBI Phospholipid/glycerol acyltransferase 3.3E-35
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_505578.1 3 4-26,33-55,122-141
T06E8.1 3 4-26,33-55,122-141
SNAP00000037761 1 15-34
Sequence
Target Sequence
>C. ELEGANS:193635_S_AT
atcagagttctctcgacattctatcgatggcatcaatctggccgaagaattgtgttgtaa
tgatgaaacgaattcttgcctatgttccattcttcaatctcggagcctacttttccaaca
caatcttcatcgatcgatataaccgtgaacgtgcgatggcttcagttgattattgtgcat
ctgaaatgaagaacagaaatcttaaactttgggtatttccggaaggaacaagaaatcgtg
aaggagggttcattccattcaagaaaggagcattcaatattgcagttcgtgcgcagattc
ccattattccagttgtattctcagactatcgggatttctactcaaagccaggccgatatt
tcaagaatgatggagaagttgttattcgagttctggatgcgattccaacaaaagggctca
ctcttgatgacgtcagcgagttgtctgatatgtgtcgggacgttatgttggcagcctat


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
ATCAGAGTTCTCTCGACATTCTATC 493 29 305 Antisense
ATCGATGGCATCAATCTGGCCGAAG 537 35 327 Antisense
AACGAATTCTTGCCTATGTTCCATT 319 145 371 Antisense
TCCATTCTTCAATCTCGGAGCCTAC 82 591 390 Antisense
TCCAACACAATCTTCATCGATCGAT 504 587 418 Antisense
GAACGTGCGATGGCTTCAGTTGATT 90 349 451 Antisense
TATTGCAGTTCGTGCGCAGATTCCC 471 663 582 Antisense
GCAGATTCCCATTATTCCAGTTGTA 209 313 597 Antisense
TGTATTCTCAGACTATCGGGATTTC 268 561 618 Antisense
AAAAGGGCTCACTCTTGATGACGTC 389 133 714 Antisense
TCGGGACGTTATGTTGGCAGCCTAT 667 597 759 Antisense
Sequence Source Affymetrix Proprietary Database