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[193634_s_at]

Description W06F12.1A /REP_DB=WormBase Gene ID /WP=CE16555 /TR=O62395 /GB=CAB05827.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase (CDC2-CDC28 subfamily)
Cluster 6grp_highest_10_10 > 90      6grp_high1_10_10 > 19      4grp_highest_8_8 > 14      4grp_high_8_8 > 14      6grp_highest_nonorm > 51      6grp_total > 02      4grp_total > 09      6grp_cgc > 42      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 588
1 2 3 4 range
A 501.2
(-3)
P 		522.2
(-2.8)
P 		574
(-2.2)
P 		1057.8
(3)
P 		557
B 507
(-3)
P 		615.3
(-1.9)
P 		711.5
(-0.9)
P 		1083.6
(3)
P 		577
C 495.3
(-3)
P 		689.3
(-0.5)
P 		580.1
(-1.9)
P 		965.9
(3)
P 		471
avr 501.2
(-3) 		608.9
(-1.8) 		621.9
(-1.6) 		1035.8
(3) 		535

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 325
1 2 3 4 5 6 range
A 571.6
(0)
P 		705.6
(3)
P 		497.9
(-1.6)
P 		435.5
(-3)
P 		654.4
(1.9)
P 		520.2
(-1.1)
P 		270
B 620.8
(0.7)
P 		697.5
(3)
P 		556.5
(-1.2)
P 		564.9
(-1)
P 		570.4
(-0.8)
P 		497.2
(-3)
P 		200
C 760.3
(3)
P 		588
(-0.4)
P 		486.8
(-2.4)
P 		533.8
(-1.5)
P 		631.7
(0.4)
P 		457.8
(-3)
P 		303
avr 650.9
(2.6) 		663.7
(3) 		513.7
(-2.2) 		511.4
(-2.3) 		618.8
(1.4) 		491.7
(-3) 		172
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 118
1 2 3 4 range
A 182.5
(3)
P 		113.3
(-3)
P 		150.1
(0.2)
P 		154.8
(0.6)
P 		69
B 161.7
(-2.3)
P 		152
(-3)
P 		164.9
(-2)
P 		230.9
(3)
P 		79
C 163.9
(-2.8)
P 		198.2
(2.4)
P 		202.2
(3)
P 		162.9
(-3)
P 		39
avr 169.4
(0.1) 		154.5
(-3) 		172.4
(0.8) 		182.9
(3) 		28

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 176
1 2 3 4 5 6 range
A 105.4
(-3)
P 		250.9
(3)
P 		108.4
(-2.9)
P 		110.5
(-2.8)
P 		197.5
(0.8)
P 		126.7
(-2.1)
P 		146
B 216
(2)
P 		232.2
(3)
P 		135.1
(-3)
P 		149.6
(-2.1)
P 		231.7
(3)
P 		185.4
(0.1)
P 		97
C 281.8
(3)
P 		179.4
(-0.5)
P 		123.9
(-2.4)
P 		107.4
(-3)
P 		204.4
(0.3)
P 		153.3
(-1.4)
P 		174
avr 201.1
(1.8) 		220.8
(3) 		122.5
(-3) 		122.5
(-3) 		211.2
(2.4) 		155.1
(-1) 		98
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193634_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7828
Sequence Type Exemplar sequence
Representative Public ID W06F12.1A NCBI
Target Description W06F12.1A /REP_DB=WormBase Gene ID /WP=CE16555 /TR=O62395 /GB=CAB05827.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase (CDC2-CDC28 subfamily)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001027637(11), NM_001027634(11), NM_001027635(11), NM_001027638(11), NM_001027636(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001027637 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
NM_001027634 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
NM_001027635 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
NM_001027638 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
NM_001027636 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
GENEFINDER00000027468 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:13713586:13722979:1 11/11 None
SNAP00000027463 ENSEMBL cdna:SNAP chromosome:CEL140:III:13721225:13722979:1 11/11 None
W06F12.1d ENSEMBL cdna:known chromosome:CEL140:III:13701509:13723917:1 gene:W06F12.1 11/11 A 
W06F12.1a ENSEMBL cdna:known chromosome:CEL140:III:13713561:13723089:1 gene:W06F12.1 11/11 A 
W06F12.1e ENSEMBL cdna:known chromosome:CEL140:III:13714088:13722979:1 gene:W06F12.1 11/11 A 
W06F12.1b ENSEMBL cdna:known chromosome:CEL140:III:13717369:13723917:1 gene:W06F12.1 11/11 A 
W06F12.1c ENSEMBL cdna:known chromosome:CEL140:III:13718890:13722979:1 gene:W06F12.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:13713556-13723085(+) 100.0 100.0
Public Domain and Genome References
Ensembl W06F12.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAH10786 Hypothetical protein W06F12.1d [Caenorhabditis elegans] emb|CAH10804.1| Hypothetical protein W06F12.1d [Caenorhabditis elegans] ref|NP_001022808.1| Loss of InTestine family member (lit-1) [Caenorhabditis elegans] 0.0
blast CAB05827 Hypothetical protein W06F12.1a [Caenorhabditis elegans] ref|NP_001022805.1| Loss of InTestine family member (lit-1) [Caenorhabditis elegans] gb|AAD39815.1| LIT-1 [Caenorhabditis elegans] 0.0
blast CAB60300 Hypothetical protein W06F12.1b [Caenorhabditis elegans] ref|NP_001022806.1| Loss of InTestine family member (lit-1) [Caenorhabditis elegans] gb|AAD37361.1| protein kinase LIT-1b [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-69
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 9.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 7.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-51
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 2.0E-71
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 6.0E-72
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 3.0E-72
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 2.0E-72
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 8.0E-73
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 3.0E-52
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.3E-60
Sequence
Target Sequence 
>C. ELEGANS:193634_S_AT
gaaccccatcgcaagaggctatgaaatacgcttgtgagggagccaagaaccatgtgctcc
gcgccggtcttcgagctcctgacacacagaggctgtacaagatcgcatcgcctgatgata
agaatcacgaggcggtggatttactgcagaagcttctgcacttcgatccggataagagaa
ttagtgtggaggaggcactgcaacatcgatatttagaagaagggcgtctgcgattccact
cgtgtatgtgctcgtgctgctatacgaaaccaaatatgccgtcgaggttgttcgcgcagg
atttggatccacgtcacgagagcccattcgatccaaagtgggagaaggacatgtcccgac
tatcgatgtttgagctccgcgagaaaatgtaccaatttgtgatggacaggcctgcgttgt
acggtgtcgccctttgcataaatccccaatcggcggcctacaagaactttgcaagctcgt
cagttgctcaggc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACCCCATCGCAAGAGGCTATGAA 376 347 1391 Antisense
AGCTCCTGACACACAGAGGCTGTAC 631 79 1464 Antisense
GGCTGTACAAGATCGCATCGCCTGA 148 541 1481 Antisense
CTTCTGCACTTCGATCCGGATAAGA 252 221 1543 Antisense
ATTCCACTCGTGTATGTGCTCGTGC 228 7 1623 Antisense
AATATGCCGTCGAGGTTGTTCGCGC 547 171 1663 Antisense
ACGAGAGCCCATTCGATCCAAAGTG 517 91 1706 Antisense
CGACTATCGATGTTTGAGCTCCGCG 634 251 1747 Antisense
CCTTTGCATAAATCCCCAATCGGCG 14 269 1821 Antisense
AATCGGCGGCCTACAAGAACTTTGC 151 169 1838 Antisense
TTGCAAGCTCGTCAGTTGCTCAGGC 433 701 1859 Antisense
Sequence Source Affymetrix Proprietary Database