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[193612_at] deoxyuridine 5'-triphosphate nucleotidohydrolase

Description K07A1.2 /REP_DB=WormBase Gene ID /WP=CE18855 /TR=O01934 /GB=CAB03175.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=deoxyuridine 5prime-triphosphate nucleotidohydrolase
Cluster 6grp_highest_10_10 > 88      6grp_high1_10_10 > 88      4grp_highest_8_8 > 02      4grp_high_8_8 > 46      6grp_highest_nonorm > 99      6grp_total > 98      4grp_total > 49      6grp_highest_sub > Da      6grp_high1_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 316
1 2 3 4 range
A 712
(-3)
P 		857.5
(3)
P 		809.6
(1)
P 		714.3
(-2.9)
P 		146
B 653.5
(-3)
P 		829
(0.3)
P 		969.5
(3)
P 		784.9
(-0.5)
P 		316
C 757.8
(-0.5)
P 		881.4
(3)
P 		872.9
(2.8)
P 		670.4
(-3)
P 		211
avr 707.8
(-3) 		856
(2) 		884
(3) 		723.2
(-2.5) 		176

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2633
1 2 3 4 5 6 range
A 598.1
(-2.8)
P 		555.4
(-2.9)
P 		535.6
(-3)
P 		729
(-2.5)
P 		1888.6
(0.8)
P 		2661.7
(3)
P 		2126
B 900.1
(-2.3)
P 		630.1
(-3)
P 		641.8
(-3)
P 		804.5
(-2.5)
P 		2112.8
(1)
P 		2878
(3)
P 		2248
C 847.5
(-2.2)
P 		475.2
(-3)
P 		522.6
(-2.9)
P 		696.1
(-2.5)
P 		1923.2
(0.3)
P 		3108.4
(3)
P 		2633
avr 781.9
(-2.4) 		553.6
(-3) 		566.7
(-3) 		743.2
(-2.5) 		1974.9
(0.7) 		2882.7
(3) 		2329
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 200
1 2 3 4 range
A 259.2
(3)
P 		186.1
(0.2)
P 		211.6
(1.2)
P 		104.6
(-3)
P 		155
B 208.4
(1.3)
P 		204.7
(0.9)
P 		224.7
(3)
P 		167.3
(-3)
P 		57
C 250.9
(1.3)
P 		253.4
(1.4)
P 		304.2
(3)
P 		113
(-3)
P 		191
avr 239.5
(2.6) 		214.7
(1.4) 		246.8
(3) 		128.3
(-3) 		119

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 963
1 2 3 4 5 6 range
A 110.3
(-3)
P 		197.5
(-2)
P 		116.7
(-2.9)
P 		184.9
(-2.2)
P 		569.9
(2.1)
P 		648
(3)
P 		538
B 313.2
(-2)
P 		209.7
(-2.6)
P 		155.8
(-3)
P 		213.1
(-2.6)
P 		858.4
(1.6)
P 		1073.2
(3)
P 		917
C 314.1
(-1.8)
P 		145
(-2.9)
P 		133
(-3)
P 		140
(-3)
P 		622.3
(0.2)
P 		1040.5
(3)
P 		908
avr 245.9
(-2.2) 		184.1
(-2.6) 		135.2
(-3) 		179.3
(-2.7) 		683.5
(1.2) 		920.6
(3) 		785
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193612_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2187
Sequence Type Exemplar sequence
Representative Public ID K07A1.2 NCBI
Target Description K07A1.2 /REP_DB=WormBase Gene ID /WP=CE18855 /TR=O01934 /GB=CAB03175.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=deoxyuridine 5prime-triphosphate nucleotidohydrolase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026382(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026382 NCBI Caenorhabditis elegans K07A1.2 (K07A1.2) mRNA, complete cds. 11/11 None
SNAP00000041844 ENSEMBL cdna:SNAP chromosome:CEL140:I:9593544:9598088:1 11/11 None
GENEFINDER00000041859 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9593544:9595257:1 11/11 None
K07A1.2.2 ENSEMBL cdna:known chromosome:CEL140:I:9593487:9595322:1 gene:K07A1.2 11/11 None
K07A1.2.4 ENSEMBL cdna:known chromosome:CEL140:I:9593534:9595329:1 gene:K07A1.2 11/11 None
K07A1.2.1 ENSEMBL cdna:known chromosome:CEL140:I:9593540:9595329:1 gene:K07A1.2 11/11 None
K07A1.2.3 ENSEMBL cdna:known chromosome:CEL140:I:9593544:9595322:1 gene:K07A1.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9593474-9595188(+) 100.0 100.0
Public Domain and Genome References
Gene Title deoxyuridine 5'-triphosphate nucleotidohydrolase
Ensembl K07A1.2
Entrez Gene 172794 Entrez gene
SwissProt O01934 EMBL-EBI
WormBase CE18855 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:252442_AT deoxyuridine 5'-triphosphate nucleotidohydrolase family at
CANINE:1602224_AT similar to Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor (dUTPase) (dUTP pyrophosphatase) cfa
CANINE:1584568_AT similar to Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor (dUTPase) (dUTP pyrophosphatase) cfa
CANINE_2:CFA.4000.1.A1_AT similar to Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor (dUTPase) (dUTP pyrophosphatase) cfa
CANINE_2:CFA.4000.1.A1_S_AT similar to Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor (dUTPase) (dUTP pyrophosphatase) cfa
CANINE_2:CFAAFFX.22054.1.S1_AT similar to Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor (dUTPase) (dUTP pyrophosphatase) cfa
DROSOPHILA_2:1634637_A_AT Deoxyuridine triphosphatase dm
DROSGENOME1:153626_AT Deoxyuridine triphosphatase dm
HG-U133A:208956_X_AT dUTP pyrophosphatase hs
HG-U133_PLUS_2:208956_X_AT dUTP pyrophosphatase hs
HG-U133A_2:208956_X_AT dUTP pyrophosphatase hs
HG-U133A:208955_AT dUTP pyrophosphatase hs
HG-FOCUS:208955_AT dUTP pyrophosphatase hs
HG-U133A_2:208955_AT dUTP pyrophosphatase hs
HG-U133_PLUS_2:208955_AT dUTP pyrophosphatase hs
HG-U133_PLUS_2:209932_S_AT dUTP pyrophosphatase hs
HG-U133A:209932_S_AT dUTP pyrophosphatase hs
HG-U133A_2:209932_S_AT dUTP pyrophosphatase hs
HU35KSUBD:RC_AA433910_AT dUTP pyrophosphatase hs
HUGENEFL:U31930_AT dUTP pyrophosphatase hs
U133_X3P:G2735291_3P_A_AT dUTP pyrophosphatase hs
U133_X3P:G10257384_3P_AT dUTP pyrophosphatase hs
HG-U95AV2:38368_AT dUTP pyrophosphatase hs
HG-U95B:47633_AT dUTP pyrophosphatase hs
MU11KSUBB:MSA.3785.0_S_AT deoxyuridine triphosphatase mm
MU11KSUBB:MSA.33213.0_F_AT deoxyuridine triphosphatase mm
MG-U74AV2:96287_AT deoxyuridine triphosphatase mm
MOE430A:1419269_AT deoxyuridine triphosphatase mm
MOUSE430A_2:1419269_AT deoxyuridine triphosphatase mm
MOUSE430_2:1419269_AT deoxyuridine triphosphatase mm
MOE430A:1419270_A_AT deoxyuridine triphosphatase mm
MOUSE430A_2:1419270_A_AT deoxyuridine triphosphatase mm
MOUSE430_2:1419270_A_AT deoxyuridine triphosphatase mm
MG-U74CV2:137642_AT Deoxyuridine triphosphatase, mRNA (cDNA clone MGC:28500 IMAGE:4187559) mm
MU19KSUBA:TC23542_S_AT Deoxyuridine triphosphatase, mRNA (cDNA clone MGC:28500 IMAGE:4187559) mm
YEAST_2:1771246_AT dUTPase, catalyzes the hydrolysis of dUTP to dUMP and PPi and thereby prevents the incorporation of uracil into DNA during replication Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
46080 dUTP metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16787 hydrolase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03175 Hypothetical protein K07A1.2 [Caenorhabditis elegans] ref|NP_001021553.1| K07A1.2 [Caenorhabditis elegans] gb|AAB57697.1| deoxyuridinetriphosphatase [Caenorhabditis elegans] 0.0
blast CAE60171 Hypothetical protein CBG03725 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR008180 EMBL-EBI DeoxyUTP pyrophosphatase 1.7E-47
Pfam IPR008180 EMBL-EBI DeoxyUTP pyrophosphatase 4.0E-52
Pfam IPR008180 EMBL-EBI DeoxyUTP pyrophosphatase 4.4E-51
Pfam IPR008180 EMBL-EBI DeoxyUTP pyrophosphatase 7.8E-35
Pfam IPR008180 EMBL-EBI DeoxyUTP pyrophosphatase 6.8E-8
Sequence
Target Sequence 
>C. ELEGANS:193612_AT
gatcggtcactgtgtctacgaagccgcaagtgaattggagaatacagaccgtggagctgg
tggctttggatcgactggacaaaatacgatggaagcggaaccagctttgaaaaaatctaa
aactgaacaaattaaaacctctgccacatcggtaacaatccaaatcacaaagagcaacga
taacgctcagatgccaacgtatggatcagccgaagctgctggagctgatttgtacagcgc
tgaagatgtcacagttccagcccgtgggaagttgtgtgtctcgacgggaattcaaatggc
attgccaatcggatactatggaagagttgctcctcgatctggactggctgccaagcattt
catcgatgttggagcaggtgtcatcgatagcgactatcgtggagaggtcaaagttcttct
tttcaatttcggcgaaaatgactttgaggtcaagaaaggagatcgaattgcacagctggt
ctgcgaacaaattgcactctgtacttactcaaaagtggagagccttgaagtcaccgagcg
tggagctggag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATCGGTCACTGTGTCTACGAAGCC 213 417 903 Antisense
CAGACCGTGGAGCTGGTGGCTTTGG 374 205 947 Antisense
AAACCTCTGCCACATCGGTAACAAT 217 125 1037 Antisense
CAACGATAACGCTCAGATGCCAACG 635 187 1077 Antisense
GCCAACGTATGGATCAGCCGAAGCT 600 277 1095 Antisense
CTGAAGATGTCACAGTTCCAGCCCG 448 237 1142 Antisense
CAGCCCGTGGGAAGTTGTGTGTCTC 708 201 1160 Antisense
GACTGGCTGCCAAGCATTTCATCGA 144 377 1244 Antisense
GAATTGCACAGCTGGTCTGCGAACA 430 323 1367 Antisense
AAATTGCACTCTGTACTTACTCAAA 470 115 1391 Antisense
GAAGTCACCGAGCGTGGAGCTGGAG 292 337 1429 Antisense
Sequence Source Affymetrix Proprietary Database