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[193556_at] Zinc finger, C4 type (two domains)

Description K06B4.1 /REP_DB=WormBase Gene ID /WP=CE25930 /GEN=nhr-51 /TR=O17927 /GB=CAB05760.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Zinc finger, C4 type (two domains)
Cluster 6grp_total > 54      4grp_total > 27      6grp_cgc > 45      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 87
1 2 3 4 range
A 24.5
(-2.3)
A 		24.8
(-2.3)
A 		14.5
(-3)
A 		101.6
(3)
A 		87
B 18.5
(-3)
A 		37.2
(-0.4)
A 		62.1
(3)
A 		22.7
(-2.4)
A 		44
C 75.1
(2.6)
A 		79.6
(3)
A 		16.1
(-3)
A 		42.4
(-0.5)
A 		64
avr 39.4
(-0.9) 		47.2
(1) 		30.9
(-3) 		55.6
(3) 		25

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 76
1 2 3 4 5 6 range
A 25.7
(-1)
A 		17.3
(-2.4)
A 		13.3
(-3)
A 		14.3
(-2.8)
A 		50.5
(3)
A 		42.4
(1.7)
A 		37
B 14.5
(-2.4)
A 		14.3
(-2.4)
A 		83.2
(3)
A 		11.8
(-2.6)
A 		7
(-3)
A 		9.6
(-2.8)
A 		76
C 15.2
(-1.7)
A 		40.6
(3)
A 		16
(-1.5)
A 		8.1
(-3)
A 		10.2
(-2.6)
A 		21.7
(-0.5)
A 		33
avr 18.5
(-1.4) 		24.1
(-0.1) 		37.5
(3) 		11.4
(-3) 		22.6
(-0.4) 		24.6
(0) 		26
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 8.9
(-0.2)
A 		5.4
(-2.1)
A 		3.8
(-3)
A 		14.9
(3)
A 		11
B 5.9
(-2.3)
A 		9.2
(-0.3)
A 		14.4
(3)
A 		4.8
(-3)
A 		10
C 24.9
(3)
A 		22.9
(2.4)
A 		5.6
(-3)
A 		7.2
(-2.5)
A 		19
avr 13.2
(3) 		12.5
(2.2) 		7.9
(-3) 		9
(-1.8) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 19
1 2 3 4 5 6 range
A 4.7
(-2.1)
A 		6.2
(-1.4)
A 		2.9
(-3)
A 		3.6
(-2.7)
A 		15.2
(3)
A 		10.3
(0.6)
A 		12
B 5
(-2.2)
A 		4.8
(-2.3)
A 		20.2
(3)
A 		3.1
(-2.9)
A 		2.8
(-3)
A 		3.6
(-2.7)
A 		17
C 5.6
(-0.8)
A 		12.4
(3)
A 		4.1
(-1.6)
A 		1.6
(-3)
A 		3.3
(-2.1)
A 		7.3
(0.2)
A 		11
avr 5.1
(-0.8) 		7.8
(1.8) 		9.1
(3) 		2.8
(-3) 		7.1
(1.1) 		7.1
(1.1) 		6
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193556_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12986
Sequence Type Exemplar sequence
Representative Public ID K06B4.1 NCBI
Target Description K06B4.1 /REP_DB=WormBase Gene ID /WP=CE25930 /GEN=nhr-51 /TR=O17927 /GB=CAB05760.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Zinc finger, C4 type (two domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074497(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074497 NCBI Caenorhabditis elegans Nuclear Hormone Receptor family member (nhr-51) (nhr-51) mRNA, complete cds. 11/11 None
SNAP00000010507 ENSEMBL cdna:SNAP chromosome:CEL140:V:15677316:15678204:1 11/11 None
GENEFINDER00000010518 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15676859:15683227:1 10/11 None
K06B4.1 ENSEMBL cdna:known chromosome:CEL140:V:15676610:15678204:1 gene:K06B4.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15676609-15678204(+) 100.0 100.0
Public Domain and Genome References
Gene Title Zinc finger, C4 type (two domains)
Gene Symbol nhr-51
Ensembl K06B4.1
Entrez Gene 180052 Entrez gene
SwissProt O17927 EMBL-EBI
WormBase CE35582 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
3707 steroid hormone receptor activity inferred from electronic annotation QuickGO AmiGO
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
20037 heme binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05760 Hypothetical protein K06B4.1 [Caenorhabditis elegans] ref|NP_506898.2| Nuclear Hormone Receptor family member (nhr-51) [Caenorhabditis elegans] 0.0
blast AAG15145 nuclear receptor NHR-51 [Caenorhabditis elegans] 0.0
blast CAB05761 Hypothetical protein K06B4.2 [Caenorhabditis elegans] ref|NP_506899.1| Nuclear Hormone Receptor family member (nhr-52) [Caenorhabditis elegans] gb|AAG15146.1| nuclear receptor NHR-52 [Caenorhabditis elegans] sp|O17928|NHR52_CAEEL Nuclear hormone receptor family member nhr-52 0.0
blast CAB05760 Hypothetical protein K06B4.1 [Caenorhabditis elegans] ref|NP_506898.2| Nuclear Hormone Receptor family member (nhr-51) [Caenorhabditis elegans] 1.0E-159
blast AAG15145 nuclear receptor NHR-51 [Caenorhabditis elegans] 1.0E-159
blast CAB05760 Hypothetical protein K06B4.1 [Caenorhabditis elegans] ref|NP_506898.2| Nuclear Hormone Receptor family member (nhr-51) [Caenorhabditis elegans] 1.0E-104
blast AAG15145 nuclear receptor NHR-51 [Caenorhabditis elegans] 1.0E-104
blast CAB05761 Hypothetical protein K06B4.2 [Caenorhabditis elegans] ref|NP_506899.1| Nuclear Hormone Receptor family member (nhr-52) [Caenorhabditis elegans] gb|AAG15146.1| nuclear receptor NHR-52 [Caenorhabditis elegans] sp|O17928|NHR52_CAEEL Nuclear hormone receptor family member nhr-52 7.0E-85
Protein Domains
Database ID Description E-Value
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.6E-48
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 4.0E-16
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 2.6E-37
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.6E-48
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.2E-46
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 4.5E-6
Sequence
Target Sequence 
>C. ELEGANS:193556_AT
acgagattgtcttttgacgccgtctggagaagatgtctacccagacgctgtccataatct
attcaaggattctccggggcttttgaacaggacatgttgtctgctggtttccaagctcat
cgagttgaaagttacaaatgaagaatatcaattgcttagcctgatattcttttgtaatcc
gacgatatcccacaatctctcggatttcgctcgaaacacgctggcctcacaccaaatcaa
atacagctctgccttattccgtcacctacaaattacaaatccaggaactgcgcctgtcag
attccaagagcttatttcacttgttcacgtcatcaatcgtgtcaccaatgacatgcaaca
cgtcagcatgatgtttcagtgtatgataccaagtttcaagttcaagcaactcgtcacaga
cacctttgtggattgtggtgttgtacagaaaaagtcgaacgttaaaattttaaacgaaaa
accgtgtgccgacagttctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACGAGATTGTCTTTTGACGCCGTCT 646 93 639 Antisense
TACCCAGACGCTGTCCATAATCTAT 195 649 676 Antisense
ATTCAAGGATTCTCCGGGGCTTTTG 217 7 699 Antisense
TGTTGTCTGCTGGTTTCCAAGCTCA 554 561 733 Antisense
GATATCCCACAATCTCTCGGATTTC 142 427 822 Antisense
GGATTTCGCTCGAAACACGCTGGCC 34 509 840 Antisense
TCAAATACAGCTCTGCCTTATTCCG 402 629 875 Antisense
CCAGGAACTGCGCCTGTCAGATTCC 276 263 919 Antisense
GAGCTTATTTCACTTGTTCACGTCA 508 387 946 Antisense
CAAGCAACTCGTCACAGACACCTTT 388 185 1041 Antisense
GAAAAACCGTGTGCCGACAGTTCTC 285 355 1114 Antisense
Sequence Source Affymetrix Proprietary Database