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[193553_s_at] guanine nucleotide-binding protein

Description R06A10.2 /REP_DB=WormBase Gene ID /WP=CE21115 /GEN=gsa-1 /TR=O18678 /GB=AAB96733.2 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=guanine nucleotide-binding protein
Cluster 6grp_total > 54      4grp_total > 28      6grp_cgc > 55      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 95
1 2 3 4 range
A 62.6
(0)
A 		63.2
(0.2)
A 		76
(3)
A 		49
(-3)
A 		27
B 84.8
(1.8)
A 		91.8
(3)
A 		58.1
(-3)
A 		83.8
(1.6)
A 		34
C 67.3
(0.4)
A 		52.3
(-0.5)
A 		13.3
(-3)
A 		108.7
(3)
A 		95
avr 71.6
(1.3) 		69.1
(0.8) 		49.1
(-3) 		80.5
(3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 69
1 2 3 4 5 6 range
A 8.6
(-3)
A 		19.6
(-2)
A 		76.7
(3)
A 		12.3
(-2.7)
A 		36.7
(-0.5)
A 		19.7
(-2)
A 		68
B 44.7
(0.4)
A 		54.9
(1.6)
A 		66.5
(3)
A 		16.6
(-3)
A 		32
(-1.1)
A 		57.4
(1.9)
A 		50
C 21.1
(-1.6)
A 		66
(3)
A 		18.6
(-1.9)
A 		48.6
(1.2)
A 		7.9
(-3)
A 		31.5
(-0.6)
A 		58
avr 24.8
(-3) 		46.8
(1.5) 		53.9
(3) 		25.8
(-2.8) 		25.5
(-2.9) 		36.2
(-0.6) 		29
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 22.8
(3)
A 		13.7
(-0.5)
A 		19.9
(1.9)
A 		7.2
(-3)
A 		16
B 27.1
(3)
A 		22.7
(1.1)
A 		13.5
(-3)
A 		17.9
(-1.1)
A 		14
C 22.3
(3)
A 		15
(0.5)
A 		4.6
(-3)
A 		18.3
(1.6)
A 		18
avr 24.1
(3) 		17.1
(-0.7) 		12.7
(-3) 		14.5
(-2.1) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 20
1 2 3 4 5 6 range
A 1.6
(-3)
A 		7
(-0.9)
A 		16.7
(3)
A 		3.1
(-2.4)
A 		11.1
(0.8)
A 		4.8
(-1.7)
A 		15
B 15.6
(1)
A 		18.3
(1.9)
A 		16.1
(1.1)
A 		4.4
(-3)
A 		13
(0)
A 		21.4
(3)
A 		17
C 7.8
(-1.2)
A 		20.1
(3)
A 		4.7
(-2.3)
A 		9.8
(-0.5)
A 		2.5
(-3)
A 		10.5
(-0.3)
A 		18
avr 8.3
(-1.4) 		15.1
(3) 		12.5
(1.3) 		5.8
(-3) 		8.9
(-1) 		12.2
(1.1) 		9
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193553_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.27
Sequence Type Exemplar sequence
Representative Public ID R06A10.2 NCBI
Target Description R06A10.2 /REP_DB=WormBase Gene ID /WP=CE21115 /GEN=gsa-1 /TR=O18678 /GB=AAB96733.2 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=guanine nucleotide-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058416(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058416 NCBI Caenorhabditis elegans G protein, Subunit Alpha family member (gsa-1) (gsa-1) mRNA, complete cds. 11/11 A 
GENEFINDER00000037730 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:1068989:1089696:1 10/11 None
SNAP00000037726 ENSEMBL cdna:SNAP chromosome:CEL140:I:1070385:1074345:1 11/11 None
R06A10.2.1 ENSEMBL cdna:known chromosome:CEL140:I:1068593:1075012:1 gene:R06A10.2 11/11 A 
R06A10.2.2 ENSEMBL cdna:known chromosome:CEL140:I:1068613:1074345:1 gene:R06A10.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:1068997-1074345(+) 100.0 100.0
Public Domain and Genome References
Gene Title guanine nucleotide-binding protein
Gene Symbol gsa-1
Ensembl R06A10.2
Entrez Gene 171687 Entrez gene
SwissProt O18678 EMBL-EBI
WormBase CE21115 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1584931_AT GNAS complex locus cfa
CANINE_2:CFA.1247.1.S1_AT GNAS complex locus cfa
CANINE_2:CFAAFFX.18882.1.S1_S_AT GNAS complex locus cfa
DROSOPHILA_2:1639015_S_AT G protein s 60A dm
DROSGENOME1:154356_AT G protein s 60A dm
CHICKEN:GGAAFFX.22266.1.S1_S_AT GNAS complex locus gga
CHICKEN:GGAAFFX.22266.2.S1_AT GNAS complex locus gga
CHICKEN:GGAAFFX.22266.2.S1_S_AT GNAS complex locus gga
CHICKEN:GGA.10262.1.S1_AT GNAS complex locus gga
HG-U133_PLUS_2:200780_X_AT GNAS complex locus hs
HG-U133A_2:200780_X_AT GNAS complex locus hs
HG-U133A:200780_X_AT GNAS complex locus hs
HG-U133_PLUS_2:200981_X_AT GNAS complex locus hs
HG-U133A_2:200981_X_AT GNAS complex locus hs
HG-U133A:200981_X_AT GNAS complex locus hs
HG-U133_PLUS_2:217058_AT GNAS complex locus hs
HG-U133A_2:217058_AT GNAS complex locus hs
HG-U133A:217058_AT GNAS complex locus hs
HG-U95AV2:37450_R_AT GNAS complex locus hs
HG-U133_PLUS_2:214548_X_AT GNAS complex locus hs
HG-U133A_2:214548_X_AT GNAS complex locus hs
HG-U133A:214548_X_AT GNAS complex locus hs
HG-U133_PLUS_2:217673_X_AT GNAS complex locus hs
HG-U133A_2:217673_X_AT GNAS complex locus hs
HG-U133A:217673_X_AT GNAS complex locus hs
HG-U133_PLUS_2:211858_X_AT GNAS complex locus hs
HG-U133A:211858_X_AT GNAS complex locus hs
HG-U133A_2:211858_X_AT GNAS complex locus hs
HU35KSUBC:RC_W88587_AT GNAS complex locus hs
HUGENEFL:M21142_CDS2_S_AT GNAS complex locus hs
HG-U133_PLUS_2:217057_S_AT GNAS complex locus hs
HG-U133A_2:217057_S_AT GNAS complex locus hs
HG-FOCUS:217057_S_AT GNAS complex locus hs
HG-U133A:217057_S_AT GNAS complex locus hs
U133_X3P:G3552031_3P_A_AT GNAS complex locus hs
U133_X3P:G3552031_3P_S_AT GNAS complex locus hs
U133_X3P:HS.325202.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.273385.2.A1_3P_S_AT GNAS complex locus hs
U133_X3P:HS.273385.1.A1_3P_S_AT GNAS complex locus hs
U133_X3P:HS.113368.3.A1_3P_A_AT GNAS complex locus hs
HG-U133A_2:212273_X_AT GNAS complex locus hs
HG-U133_PLUS_2:212273_X_AT GNAS complex locus hs
HG-U133A:212273_X_AT GNAS complex locus hs
HG-U95AV2:31604_AT GNAS complex locus hs
HG-U95AV2:37448_S_AT GNAS complex locus hs
HG-U95AV2:37449_I_AT GNAS complex locus hs
HG-U95B:46156_AT GNAS complex locus hs
HG-U95C:63729_F_AT GNAS complex locus hs
HG-U95E:79959_R_AT GNAS complex locus hs
HG-U133A:214157_AT GNAS complex locus hs
HG-U133_PLUS_2:214157_AT GNAS complex locus hs
HG-U133A_2:214157_AT GNAS complex locus hs
HG-FOCUS:214157_AT GNAS complex locus hs
HG-U133_PLUS_2:228173_AT GNAS complex locus hs
HG-U133B:228173_AT GNAS complex locus hs
HG-U133_PLUS_2:229274_AT GNAS complex locus hs
HG-U133B:229274_AT GNAS complex locus hs
HG-U133_PLUS_2:235851_S_AT GNAS complex locus hs
HG-U133B:235851_S_AT GNAS complex locus hs
HG-U133_PLUS_2:239037_AT GNAS complex locus hs
HG-U133B:239037_AT GNAS complex locus hs
HG-U133_PLUS_2:242816_AT GNAS complex locus hs
HG-U133B:242816_AT GNAS complex locus hs
HG-U133_PLUS_2:242975_S_AT GNAS complex locus hs
HG-U133B:242975_S_AT GNAS complex locus hs
HG-U95B:45630_AT GNAS complex locus hs
HG-U95B:46055_AT GNAS complex locus hs
HG-U95B:46155_AT GNAS complex locus hs
HG-U95B:50967_AT GNAS complex locus hs
HG-U95D:81444_AT GNAS complex locus hs
HG-U95E:83906_AT GNAS complex locus hs
HG-U95D:90463_AT GNAS complex locus hs
HG-U95D:90465_G_AT GNAS complex locus hs
HU35KSUBA:AA062932_AT GNAS complex locus hs
HU35KSUBA:AA203742_AT GNAS complex locus hs
HU35KSUBA:D81936_AT GNAS complex locus hs
HU35KSUBA:H68018_S_AT GNAS complex locus hs
HU35KSUBC:RC_AA292703_AT GNAS complex locus hs
HU35KSUBA:RC_AA192339_AT GNAS complex locus hs
HU35KSUBC:RC_AA035219_AT GNAS complex locus hs
HU35KSUBC:RC_AA251879_AT GNAS complex locus hs
U133_X3P:HS.157307.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.159354.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.159354.1.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.38057.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.46853.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.87928.0.A1_3P_AT GNAS complex locus hs
MOE430A:1453413_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1453413_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1453413_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74AV2:92672_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74AV2:102082_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1443375_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430B:1443375_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1421740_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1421740_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430A:1421740_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74AV2:93271_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1450186_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430A:1450186_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1450186_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBA:M13964_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBA:C80321_RC_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.725.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.35032.0_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.24250.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.19335.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.8432.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74BV2:105048_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430A:1427789_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1427789_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1427789_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74CV2:167920_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOE430B:1444767_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOUSE430_2:1444767_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MG-U74CV2:129891_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOE430B:1443007_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOUSE430_2:1443007_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU11KSUBB:MSA.17559.0_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC17254_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18591_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18592_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18592_I_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18593_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC35899_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC38249_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC39144_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC39145_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
RG-U34A:AF093569MRNA#1_S_AT XLas protein rn
RN-U34:RC_AI237836_AT XLas protein rn
RG-U34A:RC_AI237836_AT XLas protein rn
RG-U34A:X84047CDS_AT XLas protein rn
RG-U34A:RC_AI237836_G_AT XLas protein rn
RAE230A:1369897_S_AT XLas protein rn
RAT230_2:1369897_S_AT XLas protein rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4871 signal transducer activity inferred from electronic annotation QuickGO AmiGO
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB96733 G protein, subunit alpha protein 1 [Caenorhabditis elegans] ref|NP_490817.3| G protein, Subunit Alpha family member (gsa-1) [Caenorhabditis elegans] gb|AAG32094.1| heterotrimeric G protein alpha subunit [Caenorhabditis elegans] dbj|BAA22402.1| G protein alpha subunit [Caenorhabditis elegans] dbj|BAA22401.1| G protein a(s) subunit [Caenorhabditis elegans] 0.0
blast AAW02912 gsa-1 [Caenorhabditis briggsae] 0.0
blast CAE74357 Hypothetical protein CBG22078 [Caenorhabditis briggsae] 0.0
blast AAB96733 G protein, subunit alpha protein 1 [Caenorhabditis elegans] ref|NP_490817.3| G protein, Subunit Alpha family member (gsa-1) [Caenorhabditis elegans] gb|AAG32094.1| heterotrimeric G protein alpha subunit [Caenorhabditis elegans] dbj|BAA22402.1| G protein alpha subunit [Caenorhabditis elegans] dbj|BAA22401.1| G protein a(s) subunit [Caenorhabditis elegans] 1.0E-168
Protein Domains
Database ID Description E-Value
Pfam IPR001019 EMBL-EBI Guanine nucleotide binding protein (G-protein), alpha subunit 1.0E-126
Pfam IPR001019 EMBL-EBI Guanine nucleotide binding protein (G-protein), alpha subunit 1.7E-37
Pfam IPR001019 EMBL-EBI Guanine nucleotide binding protein (G-protein), alpha subunit 2.3E-107
Pfam IPR001019 EMBL-EBI Guanine nucleotide binding protein (G-protein), alpha subunit 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000037730 7 132-154,448-470,480-502,509-531,566-588,609-631,658-680
Sequence
Target Sequence 
>C. ELEGANS:193553_S_AT
acaactacgatccatccgagcaggacatccttcggtgtcgtgtcatgacaaccggcattt
tcgagaccaagtttgaagtggacaaagttagatttcacatgtttgatgttggaggtcaac
gtgacgagagaagaaagtggattcagtgcttcaatgacgtgacggccatcatttttgtgt
gcgcgtcgtcttcatataatcttgtactctgggaggacaatacacaaaatcgcctccgcg
aatccctggccctattcaaaaacatctggaacaaccgctggctgaaaaccatctcggtca
tccttttcctcaacaaacaagacctgttatccgagaaaatcaaggccaagcgataccttt
tggagtcgttcttccccgaattcgagggctacaatttgcctaatgacgcggtgttcgata
atcaggaggacaaggacgtcgtccgcgccaagtactttattcgcggagagtttttgagaa
tatccacggcgaacagcgatggtcgtcatcattgctacccccacttcacgtgcgccgtcg
acacagagaacatc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACAACTACGATCCATCCGAGCAGGA 4 113 518 Antisense
CCGAGCAGGACATCCTTCGGTGTCG 608 241 533 Antisense
TGACAACCGGCATTTTCGAGACCAA 708 571 563 Antisense
TGACGTGACGGCCATCATTTTTGTG 446 569 672 Antisense
TGCGCGTCGTCTTCATATAATCTTG 6 585 697 Antisense
ATCCCTGGCCCTATTCAAAAACATC 253 37 759 Antisense
AAACATCTGGAACAACCGCTGGCTG 660 127 777 Antisense
GTCATCCTTTTCCTCAACAAACAAG 139 467 814 Antisense
TTCTTCCCCGAATTCGAGGGCTACA 474 689 886 Antisense
GGAGGACAAGGACGTCGTCCGCGCC 564 515 942 Antisense
GTGCGCCGTCGACACAGAGAACATC 24 479 1047 Antisense
Sequence Source Affymetrix Proprietary Database