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[193549_at] tyrosine-protein kinase (KIN15/KIN16 subfamily)

Description M01B2.1 /REP_DB=WormBase Gene ID /WP=CE16263 /TR=O17955 /GB=CAB05559.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (KIN15-KIN16 subfamily)
Cluster 4grp_highest_8_8 > 39      4grp_high_8_8 > 12      6grp_total > 30      4grp_total > 12      6grp_cgc > 73      6grp_cgc_sub > 02_03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 161
1 2 3 4 range
A 104.2
(-1.9)
P 		107.6
(-1.6)
P 		89.7
(-3)
P 		168.7
(3)
P 		79
B 117.3
(-0.2)
P 		71
(-3)
P 		70.3
(-3)
P 		172.2
(3)
P 		102
C 113.3
(-1.8)
P 		91.1
(-2.7)
P 		82.4
(-3)
P 		231.7
(3)
P 		149
avr 111.6
(-1.3) 		89.9
(-2.5) 		80.8
(-3) 		190.9
(3) 		110

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 147
1 2 3 4 5 6 range
A 102.1
(0.5)
P 		98.7
(0.3)
P 		163.8
(3)
P 		115.8
(1)
P 		121.7
(1.3)
P 		16.5
(-3)
A 		147
B 66
(-0.6)
P 		111.3
(2.3)
P 		111.2
(2.3)
P 		77.8
(0.2)
P 		121.4
(3)
P 		28.3
(-3)
A 		93
C 47.2
(-1.9)
P 		143.7
(3)
P 		79.1
(-0.3)
P 		136.1
(2.6)
P 		40.5
(-2.2)
P 		25.3
(-3)
A 		118
avr 71.8
(0.1) 		117.9
(3) 		118
(3) 		109.9
(2.5) 		94.5
(1.5) 		23.4
(-3) 		95
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 38
(3)
P 		23.4
(-3)
P 		23.4
(-3)
P 		24.7
(-2.5)
P 		15
B 37.4
(3)
P 		17.5
(-2.7)
P 		16.3
(-3)
P 		36.7
(2.8)
P 		21
C 37.5
(2.3)
P 		26.2
(-3)
P 		28.7
(-1.8)
P 		39.1
(3)
P 		13
avr 37.6
(3) 		22.4
(-3) 		22.8
(-2.8) 		33.5
(1.4) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 45
1 2 3 4 5 6 range
A 18.8
(-0.3)
P 		35.1
(2.7)
P 		35.7
(2.8)
P 		29.4
(1.7)
P 		36.7
(3)
P 		4
(-3)
A 		33
B 23
(-1.1)
P 		37.1
(1.1)
P 		27
(-0.4)
P 		20.6
(-1.4)
P 		49.3
(3)
P 		10.5
(-3)
A 		39
C 17.5
(-1.5)
P 		43.9
(3)
P 		20.1
(-1)
P 		27.4
(0.2)
P 		13.1
(-2.2)
P 		8.5
(-3)
A 		35
avr 19.8
(-0.7) 		38.7
(3) 		27.6
(0.9) 		25.8
(0.5) 		33
(1.9) 		7.7
(-3) 		31
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193549_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14289
Sequence Type Exemplar sequence
Representative Public ID M01B2.1 NCBI
Target Description M01B2.1 /REP_DB=WormBase Gene ID /WP=CE16263 /TR=O17955 /GB=CAB05559.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (KIN15-KIN16 subfamily)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074370(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074370 NCBI Caenorhabditis elegans protein KINase family member (kin-30) (kin-30) mRNA, complete cds. 11/11 None
GENEFINDER00000027844 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15244170:15249687:1 9/11 None
M01B2.1 ENSEMBL cdna:known chromosome:CEL140:V:15247342:15250295:1 gene:M01B2.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000027836 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15247348-15250073(+) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase (KIN15/KIN16 subfamily)
Gene Symbol kin-30
Ensembl M01B2.1
Entrez Gene 180032 Entrez gene
SwissProt O17955 EMBL-EBI
WormBase CE38529 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB05559 Hypothetical protein M01B2.1 [Caenorhabditis elegans] ref|NP_506771.2| protein KINase family member (kin-30) [Caenorhabditis elegans] 0.0
blast CAB05568 Hypothetical protein M01B2.6 [Caenorhabditis elegans] ref|NP_506770.2| M01B2.6 [Caenorhabditis elegans] 0.0
blast CAA93871 Hypothetical protein R09D1.12 [Caenorhabditis elegans] ref|NP_496025.1| R09D1.12 [Caenorhabditis elegans] 1.0E-138
blast CAA93871 Hypothetical protein R09D1.12 [Caenorhabditis elegans] ref|NP_496025.1| R09D1.12 [Caenorhabditis elegans] 1.0E-137
blast CAA93871 Hypothetical protein R09D1.12 [Caenorhabditis elegans] ref|NP_496025.1| R09D1.12 [Caenorhabditis elegans] 1.0E-123
blast CAD24482 Hypothetical protein M176.6b [Caenorhabditis elegans] ref|NP_741034.1| protein KINase family member (kin-15) [Caenorhabditis elegans] 1.0E-75
blast CAD24482 Hypothetical protein M176.6b [Caenorhabditis elegans] ref|NP_741034.1| protein KINase family member (kin-15) [Caenorhabditis elegans] 7.0E-75
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.3E-53
Pfam IPR000719 EMBL-EBI Protein kinase 4.5E-42
Pfam IPR001223 EMBL-EBI Glycoside hydrolase, family 18 8.7E-108
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506771.2 1 27-49
M01B2.1 1 27-49
GENEFINDER00000027844 2 30-52,484-506
Sequence
Target Sequence 
>C. ELEGANS:193549_AT
gtgcatcgtgatttggcgttgcggaatgtttttgtaaagagaaacaagatgattcgaata
ggagactttgggttggccagacatcatagcaaaaaatcttattacagaatgcaatgcaat
cctgatacaccattacctattttttggcttgcacctgaatgtttcaatgaatcaaagttc
actgaaatgactgatgtttggtcttatggtgtttgtctttttgaacttttttcacttgga
gaatcaccttataaaaaacttcacaattcaccgtcttacgatgtggtgcattatttgaag
aaagggtacagactctcagccccaagatattgcaatgcagaaatatacgagttcatgttg
tattgctggaatatcgatgcaactcttcggcctaaatttactgaatgcaaggacttttgt
aaaagtttaataactcggaaaaaggtggggcacctcaaaaaaatcgagtctcgtctgcaa
atggaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGCATCGTGATTTGGCGTTGCGGA 345 481 946 Antisense
GGAGACTTTGGGTTGGCCAGACATC 554 519 1006 Antisense
TGCAATCCTGATACACCATTACCTA 213 577 1060 Antisense
ATTACCTATTTTTTGGCTTGCACCT 348 5 1077 Antisense
TTGGCTTGCACCTGAATGTTTCAAT 534 705 1089 Antisense
TGGTCTTATGGTGTTTGTCTTTTTG 221 553 1144 Antisense
AAACTTCACAATTCACCGTCTTACG 229 129 1201 Antisense
GAAAGGGTACAGACTCTCAGCCCCA 410 359 1245 Antisense
ACTCTCAGCCCCAAGATATTGCAAT 659 99 1257 Antisense
AATATCGATGCAACTCTTCGGCCTA 567 171 1315 Antisense
AATCGAGTCTCGTCTGCAAATGGAA 537 167 1407 Antisense
Sequence Source Affymetrix Proprietary Database