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[193539_at] Acetyltransferase (GNAT) family

Description B0024.12 /REP_DB=WormBase Gene ID /WP=CE05156 /GEN=gna-1 /TR=SW:Q17427 /GB=CAA94884.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Acetyltransferase (GNAT) family
Cluster 6grp_highest_10_10 > 44      6grp_high1_10_10 > 43      4grp_highest_8_8 > 02      4grp_high_8_8 > 54      6grp_highest_nonorm > 61      6grp_total > 30      4grp_total > 49      6grp_highest_sub > 02      6grp_cgc > 72      6grp_high1_sub > 02      6grp_cgc_sub > 02      6grp_total_sub > Hat      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 338
1 2 3 4 range
A 299.8
(-3)
P 		405.8
(0.6)
P 		476.4
(3)
P 		318.2
(-2.4)
P 		177
B 247
(-2.2)
P 		461
(1.7)
P 		533.6
(3)
P 		206
(-3)
P 		328
C 263.5
(-3)
P 		543.7
(3)
P 		462.2
(1.3)
P 		280.8
(-2.6)
P 		280
avr 270.1
(-3) 		470.2
(2.4) 		490.7
(3) 		268.3
(-3) 		222

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 712
1 2 3 4 5 6 range
A 484.5
(2.5)
P 		382
(0.8)
P 		511.7
(3)
P 		401.7
(1.2)
P 		289.1
(-0.7)
P 		152.4
(-3)
P 		359
B 318.5
(-2.5)
P 		372.6
(-1.2)
P 		555.6
(3)
P 		364.9
(-1.4)
P 		297.2
(-3)
P 		308.1
(-2.7)
P 		258
C 332.4
(-2.2)
P 		864.7
(3)
P 		395
(-1.6)
P 		488.1
(-0.7)
P 		248.2
(-3)
P 		482.3
(-0.7)
P 		617
avr 378.5
(-0.7) 		539.8
(3) 		487.4
(1.8) 		418.2
(0.2) 		278.2
(-3) 		314.3
(-2.2) 		262
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 117
1 2 3 4 range
A 109.1
(1.8)
P 		88.1
(0.2)
P 		124.5
(3)
P 		46.6
(-3)
P 		78
B 78.8
(-0.4)
P 		113.8
(2.3)
P 		123.6
(3)
P 		43.9
(-3)
P 		80
C 87.2
(-0.9)
P 		156.3
(2.7)
P 		161.1
(3)
P 		47.3
(-3)
P 		114
avr 91.7
(0) 		119.4
(1.9) 		136.4
(3) 		45.9
(-3) 		91

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 227
1 2 3 4 5 6 range
A 89.3
(0.2)
P 		135.9
(3)
P 		111.4
(1.5)
P 		101.9
(0.9)
P 		87.2
(0)
P 		37.1
(-3)
P 		99
B 110.8
(-0.8)
P 		124
(1.3)
P 		134.9
(3)
P 		96.6
(-3)
P 		120.7
(0.8)
P 		114.9
(-0.1)
P 		38
C 123.2
(-1.6)
P 		263.8
(3)
P 		100.5
(-2.3)
P 		98.2
(-2.4)
P 		80.3
(-3)
P 		161.4
(-0.3)
P 		184
avr 107.8
(-2.1) 		174.6
(3) 		115.6
(-1.5) 		98.9
(-2.8) 		96.1
(-3) 		104.5
(-2.4) 		79
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193539_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12055
Sequence Type Exemplar sequence
Representative Public ID B0024.12 NCBI
Target Description B0024.12 /REP_DB=WormBase Gene ID /WP=CE05156 /GEN=gna-1 /TR=SW:Q17427 /GB=CAA94884.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Acetyltransferase (GNAT) family
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073253(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073253 NCBI Caenorhabditis elegans Glucosamine phosphate N-Acetyl transferase family member (gna-1) (gna-1) mRNA, complete cds. 11/11 None
SNAP00000027138 ENSEMBL cdna:SNAP chromosome:CEL140:V:10322234:10322731:-1 11/11 None
GENEFINDER00000027146 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10322234:10322731:-1 11/11 None
B0024.12 ENSEMBL cdna:known chromosome:CEL140:V:10322234:10322731:-1 gene:B0024.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10322233-10322731(-) 100.0 100.0
Public Domain and Genome References
Gene Title Acetyltransferase (GNAT) family
Gene Symbol gna-1
Ensembl B0024.12
Entrez Gene 179437 Entrez gene
SwissProt Q17427 EMBL-EBI
WormBase CE05156 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:246518_AT GCN5-related N-acetyltransferase (GNAT) family protein at
CANINE:1604153_AT similar to glucosamine-phosphate N-acetyltransferase 1 cfa
CANINE:1604218_AT similar to glucosamine-phosphate N-acetyltransferase 1 cfa
CANINE_2:CFA.1666.1.S1_AT similar to glucosamine-phosphate N-acetyltransferase 1 cfa
CANINE_2:CFAAFFX.22817.1.S1_AT similar to glucosamine-phosphate N-acetyltransferase 1 cfa
CANINE_2:CFAAFFX.22817.1.S1_S_AT similar to glucosamine-phosphate N-acetyltransferase 1 cfa
DROSOPHILA_2:1626181_AT dm
DROSOPHILA_2:1637778_A_AT dm
DROSOPHILA_2:1636543_A_AT dm
DROSGENOME1:154922_AT dm
CHICKEN:GGA.10583.2.S1_A_AT glucosamine-phosphate N-acetyltransferase 1 gga
HG-U133_PLUS_2:225853_AT glucosamine-phosphate N-acetyltransferase 1 hs
HG-U133B:225853_AT glucosamine-phosphate N-acetyltransferase 1 hs
HU35KSUBA:HUM_ALU_AT glucosamine-phosphate N-acetyltransferase 1 hs
HU35KSUBB:HUM_ALU_AT glucosamine-phosphate N-acetyltransferase 1 hs
HU35KSUBC:HUM_ALU_AT glucosamine-phosphate N-acetyltransferase 1 hs
HU35KSUBD:HUM_ALU_AT glucosamine-phosphate N-acetyltransferase 1 hs
HUGENEFL:HUM_ALU_AT glucosamine-phosphate N-acetyltransferase 1 hs
HC-G110:HUM_ALU_AT glucosamine-phosphate N-acetyltransferase 1 hs
HU35KSUBB:RC_N32919_AT glucosamine-phosphate N-acetyltransferase 1 hs
HU35KSUBB:RC_N25262_AT glucosamine-phosphate N-acetyltransferase 1 hs
U133_X3P:HS.27931.0.S1_3P_AT glucosamine-phosphate N-acetyltransferase 1 hs
HG-U95C:57358_I_AT glucosamine-phosphate N-acetyltransferase 1 hs
HG-U95C:57359_R_AT glucosamine-phosphate N-acetyltransferase 1 hs
HG-U95C:61630_AT glucosamine-phosphate N-acetyltransferase 1 hs
HG-U95C:65257_AT glucosamine-phosphate N-acetyltransferase 1 hs
HG-U95E:88477_AT glucosamine-phosphate N-acetyltransferase 1 hs
HU35KSUBB:RC_R12383_AT Glucosamine-phosphate N-acetyltransferase 1 hs
MU11KSUBA:AA414995_RC_AT glucosamine-phosphate N-acetyltransferase 1 mm
MG-U74AV2:94369_AT glucosamine-phosphate N-acetyltransferase 1 mm
MG-U74BV2:163524_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOE430A:1423158_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOUSE430A_2:1423158_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOUSE430_2:1423158_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOE430A:1423156_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOUSE430A_2:1423156_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOUSE430_2:1423156_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOE430A:1423157_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOUSE430A_2:1423157_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOUSE430_2:1423157_AT glucosamine-phosphate N-acetyltransferase 1 mm
MOE430B:1457807_AT Glucosamine-phosphate N-acetyltransferase 1, mRNA (cDNA clone MGC:35936 IMAGE:5065641) mm
MOUSE430_2:1457807_AT Glucosamine-phosphate N-acetyltransferase 1, mRNA (cDNA clone MGC:35936 IMAGE:5065641) mm
MU19KSUBA:TC17343_AT Glucosamine-phosphate N-acetyltransferase 1, mRNA (cDNA clone MGC:35936 IMAGE:5065641) mm
MU19KSUBB:TC30456_AT Glucosamine-phosphate N-acetyltransferase 1, mRNA (cDNA clone MGC:35936 IMAGE:5065641) mm
MU19KSUBB:TC33904_AT Glucosamine-phosphate N-acetyltransferase 1, mRNA (cDNA clone MGC:35936 IMAGE:5065641) mm
MU19KSUBC:TC41436_AT Glucosamine-phosphate N-acetyltransferase 1, mRNA (cDNA clone MGC:35936 IMAGE:5065641) mm
RAE230A:1375530_AT similar to EMeg32 protein rn
RAT230_2:1375530_AT similar to EMeg32 protein rn
RG-U34C:RC_AI072540_AT Similar to EMeg32 protein rn
YEAST_2:1771863_AT Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6048 UDP-N-acetylglucosamine biosynthesis inferred from sequence similarity QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5793 ER-Golgi intermediate compartment inferred from sequence similarity QuickGO AmiGO
5794 Golgi apparatus inferred from sequence similarity QuickGO AmiGO
5770 late endosome inferred from sequence similarity QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8080 N-acetyltransferase activity inferred from electronic annotation QuickGO AmiGO
4343 glucosamine 6-phosphate N-acetyltransferase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94884 Hypothetical protein B0024.12 [Caenorhabditis elegans] ref|NP_505654.1| Glucosamine phosphate N-Acetyl transferase family member (gna-1) [Caenorhabditis elegans] sp|Q17427|GNA1_CAEEL Glucosamine 6-phosphate N-acetyltransferase (Phosphoglucosamine transacetylase) (Phosphoglucosamine acetylase) dbj|BAA36497.1| acetyltransferase [Caenorhabditis elegans] 1.0E-88
blast CAE64790 Hypothetical protein CBG09583 [Caenorhabditis briggsae] 7.0E-77
blast CAE72184 Hypothetical protein CBG19292 [Caenorhabditis briggsae] 1.0E-41
Protein Domains
Database ID Description E-Value
Pfam IPR000182 EMBL-EBI GCN5-related N-acetyltransferase 1.3E-16
Sequence
Target Sequence 
>C. ELEGANS:193539_AT
atgtctcacatttttgatgcgtctgtgttagctccacacattccttcgaatcttcctgac
aattttaaagttcgtcccttggcaaaagacgatttctcgaaaggatatgttgatcttctg
agtcagttgacttcggtcggaaatcttgatcaggaagcatttgaaaagcgatttgaggcg
atgaggacctcggtccccaattatcatatagtcgtcatcgaagattccaattctcaaaaa
gttgttgcatctgccagtttggttgtcgaaatgaagttcattcacggggcaggaagtcgc
ggaagggttgaagatgttgtcgtggatactgaaatgcgtcgtcaaaaattaggagccgtt
cttttgaagactcttgtttctcttggaaagtctctcggagtttacaaaatttctctcgag
tgtgttcctgaacttctcccattctactcacaattcgggttccaggac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGTCTCACATTTTTGATGCGTCTG 226 49 13 Antisense
TTGATGCGTCTGTGTTAGCTCCACA 546 703 26 Antisense
GAGTCAGTTGACTTCGGTCGGAAAT 522 397 132 Antisense
TTGAGGCGATGAGGACCTCGGTCCC 660 705 185 Antisense
CCTCGGTCCCCAATTATCATATAGT 611 267 200 Antisense
GCATCTGCCAGTTTGGTTGTCGAAA 547 309 259 Antisense
CATTCACGGGGCAGGAAGTCGCGGA 359 209 291 Antisense
ATTAGGAGCCGTTCTTTTGAAGACT 446 11 360 Antisense
TGTTTCTCTTGGAAAGTCTCTCGGA 351 561 387 Antisense
ATTTCTCTCGAGTGTGTTCCTGAAC 327 15 421 Antisense
CTACTCACAATTCGGGTTCCAGGAC 504 225 456 Antisense
Sequence Source Affymetrix Proprietary Database