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[193517_at] purine/pyrimidine phosphoribosyl transferase

Description R12E2.11 /REP_DB=WormBase Gene ID /WP=CE18143 /TR=O61790 /GB=AAC17032.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=purine-pyrimidine phosphoribosyl transferase
Cluster 6grp_highest_10_10 > 76      6grp_high1_10_10 > 66      4grp_highest_8_8 > 14      4grp_high_8_8 > 14      6grp_highest_nonorm > 98      6grp_total > 67      4grp_total > 09      6grp_highest_sub > Da      6grp_high1_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4710
1 2 3 4 range
A 1555.2
(-3)
P 		2165.2
(-2.2)
P 		2643.3
(-1.5)
P 		6043.8
(3)
P 		4489
B 1590.2
(-3)
P 		2002
(-2.5)
P 		2454.3
(-1.9)
P 		6265
(3)
P 		4675
C 1620
(-3)
P 		1976.5
(-2.4)
P 		2249
(-2)
P 		5377.1
(3)
P 		3757
avr 1588.5
(-3) 		2047.9
(-2.4) 		2448.9
(-1.8) 		5895.3
(3) 		4307

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1336
1 2 3 4 5 6 range
A 1068.1
(-1.7)
P 		804.4
(-3)
P 		971.7
(-2.2)
P 		892.3
(-2.6)
P 		995.2
(-2)
P 		1993.2
(3)
P 		1189
B 1203
(-1.8)
P 		1053.6
(-2.6)
P 		1121.9
(-2.2)
P 		966.4
(-3)
P 		983.7
(-2.9)
P 		2140
(3)
P 		1174
C 971.4
(-2.4)
P 		835.4
(-3)
P 		1162.2
(-1.5)
P 		1077.2
(-1.9)
P 		880.5
(-2.8)
P 		2128.6
(3)
P 		1293
avr 1080.8
(-2.1) 		897.8
(-3) 		1085.3
(-2.1) 		978.6
(-2.6) 		953.1
(-2.7) 		2087.3
(3) 		1190
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 865
1 2 3 4 range
A 566.3
(-1.6)
P 		470
(-3)
P 		691
(0.2)
P 		884.7
(3)
P 		415
B 507.1
(-2.9)
P 		494.5
(-3)
P 		568.7
(-2.5)
P 		1335.1
(3)
P 		841
C 536.3
(-3)
P 		568.3
(-2.5)
P 		783.9
(1)
P 		906.7
(3)
P 		370
avr 536.6
(-2.7) 		510.9
(-3) 		681.2
(-1.1) 		1042.2
(3) 		531

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 601
1 2 3 4 5 6 range
A 196.9
(-3)
P 		286.1
(-1.1)
P 		211.6
(-2.7)
P 		226.3
(-2.4)
P 		300.3
(-0.8)
P 		485.3
(3)
P 		288
B 418.6
(-1.2)
P 		350.7
(-2)
P 		272.4
(-2.8)
P 		256
(-3)
P 		399.7
(-1.4)
P 		798
(3)
P 		542
C 360
(-1.3)
P 		254.9
(-2.5)
P 		295.8
(-2)
P 		216.6
(-3)
P 		284.9
(-2.2)
P 		712.6
(3)
P 		496
avr 325.2
(-1.7) 		297.2
(-2.1) 		259.9
(-2.6) 		233
(-3) 		328.3
(-1.7) 		665.3
(3) 		432
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193517_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2088
Sequence Type Exemplar sequence
Representative Public ID R12E2.11 NCBI
Target Description R12E2.11 /REP_DB=WormBase Gene ID /WP=CE18143 /TR=O61790 /GB=AAC17032.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=purine-pyrimidine phosphoribosyl transferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058916(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058916 NCBI Caenorhabditis elegans R12E2.11 (R12E2.11) mRNA, complete cds. 11/11 None
SNAP00000012682 ENSEMBL cdna:SNAP chromosome:CEL140:I:4172849:4173624:-1 11/11 None
GENEFINDER00000012694 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:4172849:4173624:-1 11/11 None
R12E2.11 ENSEMBL cdna:known chromosome:CEL140:I:4172465:4173625:-1 gene:R12E2.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:4172848-4173624(-) 100.0 100.0
Public Domain and Genome References
Gene Title purine/pyrimidine phosphoribosyl transferase
Ensembl R12E2.11
Entrez Gene 172008 Entrez gene
SwissProt O61790 EMBL-EBI
WormBase CE18143 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6221 pyrimidine nucleotide biosynthesis inferred from electronic annotation QuickGO AmiGO
9116 nucleoside metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4588 orotate phosphoribosyltransferase activity inferred from electronic annotation QuickGO AmiGO
16740 transferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_491317 R12E2.11 [Caenorhabditis elegans] gb|AAC17032.1| Hypothetical protein R12E2.11 [Caenorhabditis elegans] 1.0E-123
blast CAE66738 Hypothetical protein CBG12088 [Caenorhabditis briggsae] 1.0E-106
blast CAH93152 hypothetical protein [Pongo pygmaeus] 4.0E-40
Protein Domains
Database ID Description E-Value
Pfam IPR000836 EMBL-EBI Phosphoribosyltransferase 7.2E-42
Sequence
Target Sequence 
>C. ELEGANS:193517_AT
gggagttctacctcaaatctggccagatgactccaatctacatagatcttcgcagaataa
tgagctctcctcgtgtgctccgaatggctgctcaagctatgtgtgagaaaattgtcgcct
caaacctcaaattcgattatgttgttggagtaccatatgctgcccttccacttgctaccc
ttgtatctgatattctcaatgtgccgatgcttatgaaaagaaaagaagccaaagcctacg
gaacaaagcaacttatcgaaggagtctatcagcctggtggtacagtacttcttgtcgaag
atgtcgtcacatcaggtgaatcaattcgtgagacagcagaagcaattcgcaatgagaatc
tgttggtcactgatgccatagctgttttggatagacaacagggagcaactgccaatctcg
cagaagataatcttaacttcctcagctttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGAGTTCTACCTCAAATCTGGCCA 96 495 149 Antisense
AATAATGAGCTCTCCTCGTGTGCTC 651 171 204 Antisense
TGCTCCGAATGGCTGCTCAAGCTAT 19 583 224 Antisense
AAAATTGTCGCCTCAAACCTCAAAT 694 131 256 Antisense
TGTTGGAGTACCATATGCTGCCCTT 519 563 291 Antisense
CACTTGCTACCCTTGTATCTGATAT 137 197 317 Antisense
GATATTCTCAATGTGCCGATGCTTA 302 427 337 Antisense
GGAGTCTATCAGCCTGGTGGTACAG 265 517 409 Antisense
GTTGGTCACTGATGCCATAGCTGTT 155 437 510 Antisense
AACAGGGAGCAACTGCCAATCTCGC 413 123 545 Antisense
GATAATCTTAACTTCCTCAGCTTTT 109 423 574 Antisense
Sequence Source Affymetrix Proprietary Database