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[193506_at] Leucine Rich Repeat (2 copies)

Description C08B11.1 /REP_DB=WormBase Gene ID /WP=CE01471 /GEN=zyg-11 /TR=SW:P21541 /GB=CAA86661.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies)
Cluster 6grp_highest_10_10 > 99      6grp_high1_10_10 > 99      4grp_highest_8_8 > 52      4grp_high_8_8 > 16      6grp_highest_nonorm > 96      6grp_total > 95      4grp_total > 39      6grp_cgc > 78      6grp_cgc_sub > In      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1005
1 2 3 4 range
A 1330.8
(3)
P 		467.9
(-2.6)
P 		405.4
(-3)
P 		666.3
(-1.3)
P 		925
B 938.1
(3)
P 		443.5
(-1.8)
P 		326.2
(-3)
P 		641.3
(0.1)
P 		612
C 1096.2
(3)
P 		493
(-2.6)
P 		453.6
(-3)
P 		676.1
(-0.9)
P 		643
avr 1121.7
(3) 		468.1
(-2.4) 		395.1
(-3) 		661.2
(-0.8) 		727

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 673
1 2 3 4 5 6 range
A 780.6
(-2)
P 		777.7
(-2)
P 		699.8
(-3)
P 		806
(-1.7)
P 		1186.9
(3)
P 		1047.3
(1.3)
P 		487
B 848.4
(0.5)
P 		913.1
(1.2)
P 		514.2
(-3)
P 		925.8
(1.3)
P 		1078.4
(2.9)
P 		1088.4
(3)
P 		574
C 710.2
(-2.6)
P 		753.8
(-2)
P 		681.1
(-3)
P 		1103.4
(3)
P 		912.4
(0.3)
P 		913.2
(0.3)
P 		422
avr 779.7
(-0.9) 		814.9
(-0.4) 		631.7
(-3) 		945.1
(1.4) 		1059.2
(3) 		1016.3
(2.4) 		428
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 409
1 2 3 4 range
A 484.6
(3)
P 		101.6
(-2.9)
P 		106
(-2.9)
P 		97.5
(-3)
P 		387
B 299.2
(3)
P 		109.5
(-2.1)
P 		75.6
(-3)
P 		136.7
(-1.4)
P 		224
C 362.9
(3)
P 		141.8
(-2.3)
P 		158.1
(-1.9)
P 		114
(-3)
P 		249
avr 382.2
(3) 		117.6
(-2.9) 		113.2
(-3) 		116.1
(-2.9) 		269

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 313
1 2 3 4 5 6 range
A 143.9
(-3)
P 		276.6
(0.7)
P 		152.4
(-2.8)
P 		204.4
(-1.3)
P 		358.2
(3)
P 		255
(0.1)
P 		214
B 295.2
(0.3)
P 		303.9
(0.4)
P 		124.9
(-3)
P 		245.2
(-0.7)
P 		438.2
(3)
P 		405.9
(2.4)
P 		313
C 263.2
(1.1)
P 		230
(-0.4)
P 		173.4
(-3)
P 		221.9
(-0.8)
P 		295.2
(2.5)
P 		305.7
(3)
P 		132
avr 234.1
(-0.6) 		270.2
(0.4) 		150.2
(-3) 		223.8
(-0.9) 		363.9
(3) 		322.2
(1.8) 		214
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193506_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3902
Sequence Type Exemplar sequence
Representative Public ID C08B11.1 NCBI
Target Description C08B11.1 /REP_DB=WormBase Gene ID /WP=CE01471 /GEN=zyg-11 /TR=SW:P21541 /GB=CAA86661.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063276(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063276 NCBI Caenorhabditis elegans ZYGote defective: embryonic lethal family member (zyg-11) (zyg-11) mRNA, complete cds. 11/11 None
SNAP00000039302 ENSEMBL cdna:SNAP chromosome:CEL140:II:8017614:8020303:1 11/11 None
GENEFINDER00000039314 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8017614:8020303:1 11/11 None
C08B11.1 ENSEMBL cdna:known chromosome:CEL140:II:8017602:8020687:1 gene:C08B11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8017610-8020300(+) 100.0 100.0
Public Domain and Genome References
Gene Title Leucine Rich Repeat (2 copies)
Gene Symbol zyg-11
Ensembl C08B11.1
Entrez Gene 174284 Entrez gene
SwissProt P21541 EMBL-EBI
WormBase CE01471 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1605904_S_AT similar to zyg-11 homolog B (C. elegans)-like cfa
CANINE:1605903_AT similar to zyg-11 homolog B (C. elegans)-like cfa
CANINE:1605098_AT similar to zyg-11 homolog B (C. elegans)-like cfa
CANINE_2:CFA.541.1.S1_AT similar to zyg-11 homolog B (C. elegans)-like cfa
CANINE_2:CFAAFFX.6517.1.S1_S_AT similar to zyg-11 homolog B (C. elegans)-like cfa
CHICKEN:GGA.16957.1.S1_AT similar to KIAA1730 protein gga
CHICKEN:GGAAFFX.23282.1.S1_S_AT similar to KIAA1730 protein gga
HU35KSUBA:HUM_ALU_AT zyg-11 homolog B (C. elegans) hs
HU35KSUBB:HUM_ALU_AT zyg-11 homolog B (C. elegans) hs
HU35KSUBC:HUM_ALU_AT zyg-11 homolog B (C. elegans) hs
HU35KSUBD:HUM_ALU_AT zyg-11 homolog B (C. elegans) hs
HUGENEFL:HUM_ALU_AT zyg-11 homolog B (C. elegans) hs
HC-G110:HUM_ALU_AT zyg-11 homolog B (C. elegans) hs
HU35KSUBC:RC_F02077_AT zyg-11 homolog B (C. elegans) hs
U133_X3P:HS.183745.1.S1_3P_A_AT zyg-11 homolog B (C. elegans) hs
U133_X3P:HS.183745.0.A1_3P_A_AT zyg-11 homolog B (C. elegans) hs
HG-U133_PLUS_2:225350_S_AT zyg-11 homolog B (C. elegans) hs
HG-U133B:225350_S_AT zyg-11 homolog B (C. elegans) hs
HG-U133_PLUS_2:227918_S_AT zyg-11 homolog B (C. elegans) hs
HG-U133B:227918_S_AT zyg-11 homolog B (C. elegans) hs
HG-U95C:62195_AT zyg-11 homolog B (C. elegans) hs
HG-U95E:91457_AT zyg-11 homolog B (C. elegans) hs
HU35KSUBD:RC_Z40634_AT Zyg-11 homolog B (C. elegans) hs
U133_X3P:HS.183745.1.S2_3P_AT Zyg-11 homolog B (C. elegans) hs
HG-U133_PLUS_2:225338_AT Zyg-11 homolog B (C. elegans) hs
HG-U133B:225338_AT Zyg-11 homolog B (C. elegans) hs
HG-U95B:48598_AT Zyg-11 homolog B (C. elegans) hs
MG-U74AV2:99779_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MG-U74BV2:162845_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOUSE430A_2:1446244_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOE430A:1446244_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOUSE430_2:1446244_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MU11KSUBA:N28141_RC_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MG-U74BV2:105480_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MG-U74BV2:116250_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MG-U74BV2:111337_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOE430A:1435754_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOUSE430A_2:1435754_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOUSE430_2:1435754_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOE430B:1447207_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MOUSE430_2:1447207_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MU19KSUBC:TC35114_AT DNA segment, Chr 6, Brigham & Women's Genetics 1452 expressed mm
MG-U74BV2:115421_AT MKIAA1730 protein mm
MOUSE430_2:1440679_AT MKIAA1730 protein mm
MOE430B:1440679_AT MKIAA1730 protein mm
MU19KSUBC:TC36372_AT MKIAA1730 protein mm
MU19KSUBC:TC38188_AT MKIAA1730 protein mm
MU19KSUBC:TC38188_G_AT MKIAA1730 protein mm
RAE230B:1380281_AT similar to KIAA1730 protein (predicted) rn
RAT230_2:1380281_AT similar to KIAA1730 protein (predicted) rn
Protein Similarities
Method ID Description E-Value
blast CAA86661 Hypothetical protein C08B11.1 [Caenorhabditis elegans] ref|NP_495677.1| ZYGote defective: embryonic lethal family member (zyg-11) [Caenorhabditis elegans] sp|P21541|ZYG11_CAEEL Early embryogenesis protein zyg-11 emb|CAA34493.1| zyg-11 protein [Caenorhabditis elegans] 0.0
blast CAE67778 Hypothetical protein CBG13353 [Caenorhabditis briggsae] 0.0
blast BAB21821.1 KIAA1730 protein [Homo sapiens] 2.0E-62
Protein Domains
Database ID Description E-Value
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.036
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.012
Sequence
Target Sequence 
>C. ELEGANS:193506_AT
gcagacgaaggttcttggcatcctcaacaacttggccgaagtggaagaattgcatttggg
acagctttgcaaaaacgagtatatttctgttcttatttcttgtcttgacggatcattcaa
cgaagtagattcgaaaggacggtatcgtgaagttgaacgatcttatttcgctgctggaat
tctcgctaatcttctgaccaacactgatggttgggagagtgaaaatcaacgtgacgaagc
ttgcgaaaagctcttggagcttattgagcagtatcccacacttccatcggcaatggtctc
ctacaaatctttcattccattcagtcgtattgttagagagtcaaattcgaatggggccat
catgtggtgtttgtggggagttcatcacgttcttcaacatcgcgagaagaacaaagcgcc
tacgtatgagaaaggatacatcgaaatgtttatggattccgggctttctccaatcgtcga
ggatatgtcccatggacactcgaaacacattcacaatctggatattcgtgtggttcatct
cgcacgagaaatcattgacattgtctcatgccattca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCAGACGAAGGTTCTTGGCATCCTC 301 311 1797 Antisense
GGCATCCTCAACAACTTGGCCGAAG 418 513 1813 Antisense
ATTTCTGTTCTTATTTCTTGTCTTG 397 17 1879 Antisense
TATTTCGCTGCTGGAATTCTCGCTA 146 661 1960 Antisense
TCGCTAATCTTCTGACCAACACTGA 33 587 1979 Antisense
GCTTATTGAGCAGTATCCCACACTT 242 305 2055 Antisense
GGCAATGGTCTCCTACAAATCTTTC 170 533 2085 Antisense
GGAGTTCATCACGTTCTTCAACATC 493 517 2173 Antisense
TGTTTATGGATTCCGGGCTTTCTCC 26 561 2243 Antisense
GATATTCGTGTGGTTCATCTCGCAC 472 427 2317 Antisense
CATTGACATTGTCTCATGCCATTCA 567 217 2349 Antisense
Sequence Source Affymetrix Proprietary Database