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[193496_s_at] Phosphoribosylformylglycinamidine synthase

Description F10F2.2 /REP_DB=WormBase Gene ID /WP=CE17651 /TR=SW:Q19311 /GB=CAA84656.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Phosphoribosylformylglycinamidine synthase
Cluster 6grp_highest_10_10 > 57      6grp_high1_10_10 > 85      4grp_highest_8_8 > 22      4grp_high_8_8 > 06      6grp_highest_nonorm > 95      6grp_total > 75      4grp_total > 01      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1164
1 2 3 4 range
A 378.7
(-2.6)
P 		329.9
(-3)
P 		386.8
(-2.6)
P 		1103.8
(3)
P 		774
B 352.8
(-2.8)
P 		312.6
(-3)
P 		513.1
(-1.9)
P 		1419.9
(3)
P 		1107
C 335.7
(-2.5)
P 		255.9
(-3)
P 		390.1
(-2.2)
P 		1248.1
(3)
P 		992
avr 355.7
(-2.6) 		299.5
(-3) 		430
(-2.2) 		1257.3
(3) 		958

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 912
1 2 3 4 5 6 range
A 335.8
(-3)
P 		527.5
(-1.6)
P 		688.3
(-0.4)
P 		681.5
(-0.5)
P 		713.6
(-0.2)
P 		1155.5
(3)
P 		820
B 293.7
(-3)
P 		594.4
(-0.3)
P 		693.7
(0.5)
P 		769.2
(1.2)
P 		668.6
(0.3)
P 		973.7
(3)
P 		680
C 243.8
(-3)
P 		522.6
(-1.1)
P 		999.3
(2)
P 		668.9
(-0.2)
P 		729
(0.2)
P 		1143.1
(3)
P 		899
avr 291.1
(-3) 		548.2
(-1.1) 		793.8
(0.8) 		706.5
(0.1) 		703.7
(0.1) 		1090.8
(3) 		800
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 231
1 2 3 4 range
A 137.9
(1.4)
P 		71.6
(-3)
P 		101.1
(-1)
P 		161.6
(3)
P 		90
B 112.5
(-2.1)
P 		77.2
(-3)
P 		118.9
(-1.9)
P 		302.6
(3)
P 		225
C 111.1
(-1.4)
P 		73.6
(-3)
P 		136
(-0.3)
P 		210.5
(3)
P 		137
avr 120.5
(-1.2) 		74.1
(-3) 		118.7
(-1.2) 		224.9
(3) 		151

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 321
1 2 3 4 5 6 range
A 61.9
(-3)
P 		187.6
(0.4)
P 		149.9
(-0.6)
P 		172.8
(0)
P 		215.3
(1.2)
P 		281.3
(3)
P 		219
B 102.2
(-3)
P 		197.9
(-0.8)
P 		168.5
(-1.5)
P 		203.7
(-0.7)
P 		271.6
(0.9)
P 		363.1
(3)
P 		261
C 90.4
(-3)
P 		159.4
(-1.6)
P 		254.3
(0.4)
P 		134.5
(-2.1)
P 		235.9
(-0)
P 		382.6
(3)
P 		292
avr 84.8
(-3) 		181.6
(-0.7) 		190.9
(-0.5) 		170.3
(-1) 		240.9
(0.6) 		342.3
(3) 		258
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193496_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6568
Sequence Type Exemplar sequence
Representative Public ID F10F2.2 NCBI
Target Description F10F2.2 /REP_DB=WormBase Gene ID /WP=CE17651 /TR=SW:Q19311 /GB=CAA84656.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Phosphoribosylformylglycinamidine synthase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065541(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065541 NCBI Caenorhabditis elegans F10F2.2 (F10F2.2) mRNA, complete cds. 11/11 None
SNAP00000027605 ENSEMBL cdna:SNAP chromosome:CEL140:III:4618887:4621526:-1 11/11 None
GENEFINDER00000027623 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4618887:4621679:-1 11/11 None
F10F2.2 ENSEMBL cdna:known chromosome:CEL140:III:4618848:4643245:-1 gene:F10F2.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4618886-4643245(-) 100.0 100.0
Public Domain and Genome References
Gene Title Phosphoribosylformylglycinamidine synthase
Ensembl F10F2.2
Entrez Gene 175608 Entrez gene
SwissProt Q19311 EMBL-EBI
WormBase CE17651 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260250_AT AIR synthase-related family protein at
CANINE_2:CFAAFFX.26041.1.S1_AT similar to phosphoribosylformylglycinamidine synthase cfa
DROSOPHILA_2:1629194_S_AT adenosine 2 dm
DROSGENOME1:153122_AT adenosine 2 dm
HU35KSUBA:AB002359_S_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) hs
U133_X3P:HS.105478.0.S1_3P_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) hs
HG-U133A_2:213302_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) hs
HG-U133_PLUS_2:213302_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) hs
HG-U133A:213302_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) hs
HG-U95AV2:37143_S_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) hs
MU11KSUBA:C79507_RC_F_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) mm
MG-U74BV2:115000_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) mm
MOE430B:1455496_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) mm
MOUSE430_2:1455496_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) mm
MG-U74CV2:170066_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) mm
MU19KSUBB:TC27944_AT MKIAA0361 protein mm
MU19KSUBB:TC27944_G_AT MKIAA0361 protein mm
RG-U34B:RC_AI044757_AT phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (predicted) rn
RAE230B:1377782_AT Phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (predicted) rn
RAT230_2:1377782_AT Phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (predicted) rn
RG-U34B:RC_AI009644_AT Phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (predicted) rn
RG-U34C:RC_AI235887_AT Phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6979 response to oxidative stress inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4601 peroxidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84656 Hypothetical protein F10F2.2 [Caenorhabditis elegans] ref|NP_497942.1| F10F2.2 [Caenorhabditis elegans] sp|Q19311|PUR4_CAEEL Probable phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase) 0.0
blast CAE71169 Hypothetical protein CBG18026 [Caenorhabditis briggsae] 0.0
blast XP_699007 PREDICTED: similar to phosphoribosylformylglycinamidine synthase [Danio rerio] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR010918 EMBL-EBI AIR synthase related protein, C-terminal 5.8E-24
Pfam IPR010918 EMBL-EBI AIR synthase related protein, C-terminal 7.0E-25
Pfam IPR000728 EMBL-EBI AIR synthase related protein 1.9E-24
Pfam IPR010918 EMBL-EBI AIR synthase related protein, C-terminal 7.0E-25
Pfam IPR010918 EMBL-EBI AIR synthase related protein, C-terminal 7.0E-25
Sequence
Target Sequence 
>C. ELEGANS:193496_S_AT
gctgccggtgttcaattcaacgagtctgtttcaaagcaattcgaagctttccgttcgaga
cctgacacattctcatatggagtttgtaatggatgtcagttgatggctcaattgggatgg
attggggatgaagaacagaaagggcctactgtttttttggatgaaaacgaatgtgggaga
tttgatagcagttttgggccagttaaaatcgaaaaaaacgtcagcattatgctttccgga
atggaaaactccgttctcggcctctggtcttctcatggagagggtcgcttcacctaccgt
aaccttcaaaacttccaaaatctgaagacaaatggtcaagtctgtattcgtttttgtgat
gatcgaggaatgactggcgctgatcatggatccgtgaagctaccgtacccatggaatccc
aatggatccattgatgacgtggcagctatttgtagtcgggacggacgtcatcttgctatg
atgccacatgctgacagatcattcttgacgtggcaatgggcggagtcaagtgaggttcca
tggaatgcaagattcgatcaaaagacagtggcactttccccatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTGCCGGTGTTCAATTCAACGAGT 473 297 3421 Antisense
TCCGTTCGAGACCTGACACATTCTC 290 595 3470 Antisense
GAATGGAAAACTCCGTTCTCGGCCT 203 333 3659 Antisense
TCATGGAGAGGGTCGCTTCACCTAC 421 621 3693 Antisense
CATGGATCCGTGAAGCTACCGTACC 230 209 3805 Antisense
TACCGTACCCATGGAATCCCAATGG 553 645 3821 Antisense
GTGGCAGCTATTTGTAGTCGGGACG 357 491 3859 Antisense
AGTCGGGACGGACGTCATCTTGCTA 303 59 3874 Antisense
ATCTTGCTATGATGCCACATGCTGA 11 31 3890 Antisense
GCTGACAGATCATTCTTGACGTGGC 80 297 3910 Antisense
AAAAGACAGTGGCACTTTCCCCATG 646 129 3980 Antisense
Sequence Source Affymetrix Proprietary Database