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[193494_at] insulin-like growth factor I like

Description T28B8.2 /REP_DB=WormBase Gene ID /WP=CE27217 /GEN=ins-18 /TR=O18149 /GB=CAB03444.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=insulin-like growth factor I like
Cluster 6grp_highest_10_10 > 72      6grp_high1_10_10 > 38      4grp_highest_8_8 > 39      4grp_high_8_8 > 12      6grp_highest_nonorm > 74      6grp_total > 27      4grp_total > 12      6grp_highest_sub > Cu      6grp_cgc > 06      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2734
1 2 3 4 range
A 929.2
(-2)
P 		790.5
(-2.3)
P 		476.6
(-3)
P 		3179.4
(3)
P 		2703
B 979.7
(-0.3)
P 		622
(-2.1)
P 		445.1
(-3)
P 		1635.1
(3)
P 		1190
C 985.2
(-0)
P 		602.5
(-2.2)
P 		467.3
(-3)
P 		1513
(3)
P 		1046
avr 964.7
(-1.2) 		671.7
(-2.2) 		463
(-3) 		2109.2
(3) 		1646

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 326
1 2 3 4 5 6 range
A 742.3
(3)
P 		667.5
(0.5)
P 		619.6
(-1.2)
P 		697.2
(1.5)
P 		575.3
(-2.7)
P 		565.9
(-3)
P 		176
B 792.7
(3)
P 		679.9
(0.4)
P 		611.2
(-1.2)
P 		530.7
(-3)
P 		583
(-1.8)
P 		732.9
(1.6)
P 		262
C 856.5
(3)
P 		654.2
(-1.6)
P 		684.1
(-1)
P 		594.7
(-3)
P 		663.7
(-1.4)
P 		758.1
(0.7)
P 		262
avr 797.2
(3) 		667.2
(-1.1) 		638.3
(-2) 		607.5
(-3) 		607.3
(-3) 		685.6
(-0.5) 		190
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 362
1 2 3 4 range
A 338.3
(0.8)
P 		171.6
(-2.2)
P 		124.6
(-3)
P 		465.4
(3)
P 		341
B 312.4
(2.1)
P 		153.6
(-1.8)
P 		103.1
(-3)
P 		348.4
(3)
P 		245
C 326.1
(3)
P 		173.2
(-2.6)
P 		162.9
(-3)
P 		255.1
(0.4)
P 		163
avr 325.6
(2.2) 		166.1
(-2) 		130.2
(-3) 		356.3
(3) 		226

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 198
1 2 3 4 5 6 range
A 136.8
(-2.9)
P 		237.4
(3)
P 		134.9
(-3)
P 		176.8
(-0.5)
P 		173.6
(-0.7)
P 		137.8
(-2.8)
P 		103
B 275.8
(3)
P 		226.3
(0.8)
P 		148.4
(-2.7)
P 		140.6
(-3)
P 		236.9
(1.3)
P 		273.3
(2.9)
P 		135
C 317.5
(3)
P 		199.6
(-0.6)
P 		174.1
(-1.3)
P 		119.6
(-3)
P 		214.8
(-0.1)
P 		253.8
(1.1)
P 		198
avr 243.4
(3) 		221.1
(1.6) 		152.5
(-2.6) 		145.7
(-3) 		208.4
(0.9) 		221.6
(1.7) 		98
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193494_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.901
Sequence Type Exemplar sequence
Representative Public ID T28B8.2 NCBI
Target Description T28B8.2 /REP_DB=WormBase Gene ID /WP=CE27217 /GEN=ins-18 /TR=O18149 /GB=CAB03444.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=insulin-like growth factor I like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059830(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059830 NCBI Caenorhabditis elegans INSulin related family member (ins-18) (ins-18) mRNA, complete cds. 11/11 None
SNAP00000004694 ENSEMBL cdna:SNAP chromosome:CEL140:I:8157058:8157711:1 10/11 None
T28B8.2 ENSEMBL cdna:known chromosome:CEL140:I:8155553:8157777:1 gene:T28B8.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8156982-8157642(+) 100.0 100.0
Public Domain and Genome References
Gene Title insulin-like growth factor I like
Gene Symbol ins-18
Ensembl T28B8.2
Entrez Gene 172600 Entrez gene
SwissProt O18149 EMBL-EBI
WormBase CE27217 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7582 physiological process inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5576 extracellular region inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5179 hormone activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03444 Hypothetical protein T28B8.2 [Caenorhabditis elegans] ref|NP_492231.1| INSulin related family member (ins-18) [Caenorhabditis elegans] dbj|BAA82661.1| Ceinsulin-1 [Caenorhabditis elegans] 2.0E-43
blast CAB03444 Hypothetical protein T28B8.2 [Caenorhabditis elegans] ref|NP_492231.1| INSulin related family member (ins-18) [Caenorhabditis elegans] dbj|BAA82661.1| Ceinsulin-1 [Caenorhabditis elegans] 2.0E-32
blast CAE66536 Hypothetical protein CBG11840 [Caenorhabditis briggsae] 2.0E-31
blast CAE66536 Hypothetical protein CBG11840 [Caenorhabditis briggsae] 8.0E-25
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492231.1 1 5-23
T28B8.2 1 5-23
Sequence
Target Sequence 
>C. ELEGANS:193494_AT
atgaaaatgtgcccaccaggtggttcaacattcacaatggcatggtcaatgtcgtgttcg
atgcgcaggagaaaacgagatgttggacgatatttcgaaaaacgtgctctgatcgcccca
tcaatccgtcaacttcaaacaatttgctgtcaagttggttgcaacgtgga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGAAAATGTGCCCACCAGGTGGTT 44 45 13 Antisense
GCCCACCAGGTGGTTCAACATTCAC 521 277 23 Antisense
TCAACATTCACAATGGCATGGTCAA 228 631 37 Antisense
ATGGCATGGTCAATGTCGTGTTCGA 345 53 49 Antisense
ATGGTCAATGTCGTGTTCGATGCGC 292 51 54 Antisense
CGTGTTCGATGCGCAGGAGAAAACG 512 243 65 Antisense
ACGAGATGTTGGACGATATTTCGAA 604 93 87 Antisense
TCGAAAAACGTGCTCTGATCGCCCC 514 601 107 Antisense
ATCCGTCAACTTCAAACAATTTGCT 268 33 136 Antisense
AACTTCAAACAATTTGCTGTCAAGT 403 139 143 Antisense
GCTGTCAAGTTGGTTGCAACGTGGA 115 293 158 Antisense
Sequence Source Affymetrix Proprietary Database