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[193466_s_at] glycosyl hydrolase (family 18)

Description C04F6.3 /REP_DB=WormBase Gene ID /WP=CE03923 /GEN=cht-1 /TR=SW:Q11174 /GB=AAA83586.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=glycosyl hydrolase (family 18)
Cluster 6grp_highest_10_10 > 86      6grp_high1_10_10 > 67      4grp_highest_8_8 > 58      4grp_high_8_8 > 33      6grp_highest_nonorm > 95      6grp_total > 68      4grp_total > 38      6grp_highest_sub > Da      6grp_cgc > 39      6grp_high1_sub > Da      6grp_cgc_sub > Cu      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 310
1 2 3 4 range
A 418.5
(3)
P
297.2
(0.3)
P
146.2
(-3)
P
251.4
(-0.7)
P
272
B 456.3
(3)
P
260.6
(-1.6)
P
212.8
(-2.7)
P
201.6
(-3)
P
255
C 412.3
(3)
P
253.7
(-0.9)
P
165.8
(-3)
P
230.7
(-1.4)
P
247
avr 429
(3)
270.5
(-0.7)
174.9
(-3)
227.9
(-1.7)
254

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1657
1 2 3 4 5 6 range
A 862.7
(-0.8)
P
563.6
(-1.9)
P
263.9
(-3)
P
415.7
(-2.5)
P
620.1
(-1.7)
P
1921.2
(3)
P
1657
B 712.2
(-1)
P
544.6
(-1.8)
P
284
(-3)
P
375.7
(-2.6)
P
543.8
(-1.8)
P
1572.7
(3)
P
1289
C 704.5
(-1.3)
P
467.7
(-2.4)
P
326.9
(-3)
P
326.8
(-3)
P
652.9
(-1.5)
P
1641.8
(3)
P
1315
avr 759.8
(-1)
525.3
(-2)
291.6
(-3)
372.7
(-2.7)
605.6
(-1.7)
1711.9
(3)
1420
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 116
1 2 3 4 range
A 152.4
(3)
P
64.5
(-1.6)
P
38.2
(-2.9)
P
36.8
(-3)
P
116
B 145.5
(3)
P
64.4
(-1.7)
P
49.3
(-2.6)
P
43
(-3)
P
103
C 136.5
(3)
P
73
(-0.9)
P
57.8
(-1.8)
P
38.9
(-3)
P
98
avr 144.8
(3)
67.3
(-1.4)
48.4
(-2.5)
39.6
(-3)
105

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 529
1 2 3 4 5 6 range
A 159
(-1.5)
P
200.5
(-0.9)
P
57.5
(-3)
P
105.4
(-2.3)
P
187.1
(-1.1)
P
467.7
(3)
P
410
B 247.8
(-0.9)
P
181.3
(-1.7)
P
69
(-3)
P
99.5
(-2.6)
P
220.9
(-1.2)
P
586.5
(3)
P
518
C 261.1
(-0.6)
P
142.7
(-2)
P
83.2
(-2.8)
P
65.7
(-3)
P
211.3
(-1.2)
P
549.6
(3)
P
484
avr 222.6
(-1)
174.8
(-1.6)
69.9
(-3)
90.2
(-2.7)
206.4
(-1.2)
534.6
(3)
465
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193466_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18441
Sequence Type Exemplar sequence
Representative Public ID C04F6.3 NCBI
Target Description C04F6.3 /REP_DB=WormBase Gene ID /WP=CE03923 /GEN=cht-1 /TR=SW:Q11174 /GB=AAA83586.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=glycosyl hydrolase (family 18)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076187(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_076187 NCBI Caenorhabditis elegans CHiTinase family member (cht-1) (cht-1) mRNA, complete cds. 11/11 None
SNAP00000029418 ENSEMBL cdna:SNAP chromosome:CEL140:X:3397786:3400003:-1 11/11 None
GENEFINDER00000029427 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:3397786:3400003:-1 11/11 None
C04F6.3.4 ENSEMBL cdna:known chromosome:CEL140:X:3397595:3400010:-1 gene:C04F6.3 11/11 None
C04F6.3.5 ENSEMBL cdna:known chromosome:CEL140:X:3397595:3400287:-1 gene:C04F6.3 11/11 None
C04F6.3.1 ENSEMBL cdna:known chromosome:CEL140:X:3397595:3400008:-1 gene:C04F6.3 11/11 A 
C04F6.3.3 ENSEMBL cdna:known chromosome:CEL140:X:3397595:3400006:-1 gene:C04F6.3 11/11 None
C04F6.3.2 ENSEMBL cdna:known chromosome:CEL140:X:3397595:3400004:-1 gene:C04F6.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:3397786-3400004(-) 100.0 100.0
Public Domain and Genome References
Gene Title glycosyl hydrolase (family 18)
Gene Symbol cht-1
Ensembl C04F6.3
Entrez Gene 180628 Entrez gene
SwissProt Q11174 EMBL-EBI
WormBase CE03923 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:20420_AT glycosyl hydrolase family 18 protein at
ATH1-121501:254543_AT glycosyl hydrolase family 18 protein at
DROSOPHILA_2:1639636_AT dm
DROSGENOME1:148079_AT dm
HG-U133A:208168_S_AT chitinase 1 (chitotriosidase) hs
HG-U133_PLUS_2:208168_S_AT chitinase 1 (chitotriosidase) hs
HG-FOCUS:208168_S_AT chitinase 1 (chitotriosidase) hs
HG-U133A_2:208168_S_AT chitinase 1 (chitotriosidase) hs
HU35KSUBC:RC_T94579_S_AT chitinase 1 (chitotriosidase) hs
HUGENEFL:U29615_AT chitinase 1 (chitotriosidase) hs
U133_X3P:G4502808_3P_A_AT chitinase 1 (chitotriosidase) hs
HG-U95AV2:37061_AT chitinase 1 (chitotriosidase) hs
MOUSE430_2:1453844_AT chitinase 1 (chitotriosidase) mm
MOE430B:1453844_AT chitinase 1 (chitotriosidase) mm
MG-U74CV2:171513_I_AT chitinase 1 (chitotriosidase) mm
MG-U74CV2:169743_AT chitinase 1 (chitotriosidase) mm
MG-U74CV2:170265_I_AT Chitinase 1 (chitotriosidase) (Chit1), mRNA mm
RAE230B:1391761_AT chitinase 1 (chitotriosidase) (predicted) rn
RAT230_2:1391761_AT chitinase 1 (chitotriosidase) (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
5975 carbohydrate metabolism inferred from electronic annotation QuickGO AmiGO
6030 chitin metabolism inferred from electronic annotation QuickGO AmiGO
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5576 extracellular region inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
8061 chitin binding inferred from electronic annotation QuickGO AmiGO
16787 hydrolase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA83586 Chitinase protein 1 [Caenorhabditis elegans] ref|NP_508588.1| CHiTinase family member (cht-1) [Caenorhabditis elegans] sp|Q11174|CHIT_CAEEL Probable endochitinase 0.0
blast CAE68422 Hypothetical protein CBG14201 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001223 EMBL-EBI Glycoside hydrolase, family 18 1.0E-126
Pfam IPR002557 EMBL-EBI Chitin binding Peritrophin-A 9.4E-18
Pfam IPR002557 EMBL-EBI Chitin binding Peritrophin-A 3.3E-20
Sequence
Target Sequence
>C. ELEGANS:193466_S_AT
tacccactcatcagtgtcattgctaaggagcttggaggagttatcattccaaagaaaggt
ggcgtcacaactgctccaaccactgtagcaactacggtcacaactggacgccctccaatg
acttcagcagtaaccacaactactgccgctaccacaactacaacacgtgcagctactaca
accacagcttccaatacaaatgtctgttctggaaaatcggatggattttatccaaacagc
aacaactgcggacttttcgttctttgtctgagctcaaaatcatacagcatgtcgtgccca
tcaggacttcaatactctgcttccctgaaatactgtaccacttccactgcttctggatgt
tct


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
TACCCACTCATCAGTGTCATTGCTA 441 649 1249 Antisense
AGAAAGGTGGCGTCACAACTGCTCC 584 71 1301 Antisense
GCAACTACGGTCACAACTGGACGCC 27 317 1336 Antisense
GCCCTCCAATGACTTCAGCAGTAAC 104 287 1358 Antisense
ACAACACGTGCAGCTACTACAACCA 134 111 1408 Antisense
TACAACCACAGCTTCCAATACAAAT 574 641 1425 Antisense
GCAACAACTGCGGACTTTTCGTTCT 443 319 1487 Antisense
AATCATACAGCATGTCGTGCCCATC 599 169 1526 Antisense
GCCCATCAGGACTTCAATACTCTGC 454 285 1544 Antisense
AATACTCTGCTTCCCTGAAATACTG 687 171 1559 Antisense
CACTTCCACTGCTTCTGGATGTTCT 304 197 1587 Antisense
Sequence Source Affymetrix Proprietary Database