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[193463_s_at]

Description K11E8.1C /REP_DB=WormBase Gene ID /WP=CE28053 /GEN=unc-43 /GB=CAC42359.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=calcium-calmodulin dependent protein kinase
Cluster 6grp_highest_10_10 > 41      6grp_high1_10_10 > 15      4grp_highest_8_8 > 51      4grp_high_8_8 > 32      6grp_highest_nonorm > 60      6grp_total > 15      4grp_total > 47      6grp_highest_sub > De      6grp_cgc > 23      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 439
1 2 3 4 range
A 632.3
(3)
P
247.9
(-3)
P
294.7
(-2.3)
P
312.6
(-2)
P
384
B 686.6
(3)
P
261
(-3)
P
290.5
(-2.6)
P
328.8
(-2)
P
426
C 627.7
(3)
P
350.9
(-2.2)
P
306.8
(-3)
P
333.2
(-2.5)
P
321
avr 648.9
(3)
286.6
(-3)
297.3
(-2.8)
324.9
(-2.4)
362

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 509
1 2 3 4 5 6 range
A 521.2
(3)
P
387.4
(0.7)
P
316.1
(-0.6)
P
178.8
(-3)
P
331.2
(-0.3)
P
203.3
(-2.6)
P
342
B 624.7
(3)
P
594
(2.5)
P
372.2
(-0.8)
P
288
(-2.1)
P
278.5
(-2.2)
P
226.7
(-3)
P
398
C 688.2
(3)
P
613.3
(2)
P
260.5
(-2.7)
P
334
(-1.7)
P
235.5
(-3)
P
242.1
(-2.9)
P
453
avr 611.4
(3)
531.6
(1.8)
316.3
(-1.6)
266.9
(-2.3)
281.7
(-2.1)
224
(-3)
387
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 184
1 2 3 4 range
A 230.2
(3)
P
53.8
(-2.7)
P
77
(-2)
P
45.8
(-3)
P
184
B 218.9
(3)
P
64.5
(-3)
P
67.3
(-2.9)
P
70.1
(-2.8)
P
154
C 207.8
(3)
P
100.9
(-1.2)
P
106.9
(-1)
P
56.2
(-3)
P
152
avr 219
(3)
73.1
(-2.4)
83.7
(-2)
57.4
(-3)
162

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 210
1 2 3 4 5 6 range
A 96.1
(0.3)
P
137.8
(3)
P
68.8
(-1.5)
P
45.4
(-3)
P
99.9
(0.5)
P
49.5
(-2.7)
P
92
B 217.4
(3)
P
197.7
(2.2)
P
90.4
(-2.4)
P
76.3
(-3)
P
113.2
(-1.4)
P
84.5
(-2.7)
P
141
C 255.1
(3)
P
187.1
(0.8)
P
66.3
(-3)
P
67.2
(-3)
P
76.2
(-2.7)
P
81
(-2.5)
P
189
avr 189.5
(3)
174.2
(2.3)
75.2
(-2.4)
63
(-3)
96.4
(-1.4)
71.7
(-2.6)
127
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193463_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9223
Sequence Type Exemplar sequence
Representative Public ID K11E8.1C NCBI
Target Description K11E8.1C /REP_DB=WormBase Gene ID /WP=CE28053 /GEN=unc-43 /GB=CAC42359.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=calcium-calmodulin dependent protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028131(11), NM_001028122(11), NM_001028128(11), NM_001028127(11), NM_001028124(11), NM_001028129(11), NM_001028133(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_001028131 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028122 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028128 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028127 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028124 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028129 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028133 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
K11E8.1k ENSEMBL cdna:known chromosome:CEL140:IV:10324241:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1h ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1c ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1a ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1f ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1m ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10331114:-1 gene:K11E8.1 11/11 A 
K11E8.1g ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000001602 9/11 Negative Strand Matching Probes None
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
177921 12 7 NM_001028122 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028123 187759_s_at (11), 193459_s_at (11)
NM_001028124 172058_x_at (9), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028125 172058_x_at (11), 175821_s_at (11), 175824_s_at (11), 187759_s_at (11), 193459_s_at (11)
NM_001028126 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11)
NM_001028127 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028128 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028129 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028130 172058_x_at (11), 173423_at (11), 193459_s_at (11)
NM_001028131 175821_s_at (11), 175824_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028132 172058_x_at (9), 175821_s_at (11), 175824_s_at (11), 193459_s_at (11)
NM_001028133 175821_s_at (11), 193463_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10324972-10339607(-) 100.0 100.0
Public Domain and Genome References
Ensembl K11E8.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA94242 Hypothetical protein K11E8.1a [Caenorhabditis elegans] emb|CAC42358.1| Hypothetical protein K11E8.1a [Caenorhabditis elegans] ref|NP_001023293.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] 0.0
blast CAC42327 Hypothetical protein K11E8.1f [Caenorhabditis elegans] emb|CAC42365.1| Hypothetical protein K11E8.1f [Caenorhabditis elegans] ref|NP_001023298.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63323.1| calcium/calmodulin-dependent protein kinase II isoform E [Caenorhabditis elegans] 0.0
blast CAC42323 Hypothetical protein K11E8.1g [Caenorhabditis elegans] emb|CAC42361.1| Hypothetical protein K11E8.1g [Caenorhabditis elegans] ref|NP_001023299.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63320.1| calcium/calmodulin-dependent protein kinase II isoform B [Caenorhabditis elegans] 0.0
blast CAA94244 Hypothetical protein K11E8.1c [Caenorhabditis elegans] emb|CAC42359.1| Hypothetical protein K11E8.1c [Caenorhabditis elegans] ref|NP_001023295.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 7.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 7.0E-67
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-67
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-67
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-68
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-137
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-138
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.3E-97
Sequence
Target Sequence
>C. ELEGANS:193463_S_AT
aggtggtggacagctgaaacacgagaacacggttgtccgggctgatggtgcaactggaat
cgtctcatcttccaactcatctacagccagcaagtcttcgtcaacaaatctatcagctca
aaaacagga


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
AGGTGGTGGACAGCTGAAACACGAG 246 57 1617 Antisense
GAAACACGAGAACACGGTTGTCCGG 664 355 1632 Antisense
GAACACGGTTGTCCGGGCTGATGGT 447 349 1641 Antisense
GGTTGTCCGGGCTGATGGTGCAACT 110 509 1647 Antisense
GGCTGATGGTGCAACTGGAATCGTC 395 539 1656 Antisense
ACTGGAATCGTCTCATCTTCCAACT 12 97 1669 Antisense
TCCAACTCATCTACAGCCAGCAAGT 43 589 1687 Antisense
TCTACAGCCAGCAAGTCTTCGTCAA 699 613 1696 Antisense
GCAAGTCTTCGTCAACAAATCTATC 491 321 1706 Antisense
TTCGTCAACAAATCTATCAGCTCAA 528 695 1713 Antisense
CAAATCTATCAGCTCAAAAACAGGA 237 193 1721 Antisense
Sequence Source Affymetrix Proprietary Database