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[193458_s_at] guanine nucleotide-binding protein

Description C26C6.2 /REP_DB=WormBase Gene ID /WP=CE05311 /GEN=goa-1 /TR=Q18205 /GB=CAA96595.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=guanine nucleotide-binding protein
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 16      4grp_highest_8_8 > 42      4grp_high_8_8 > 49      6grp_highest_nonorm > 40      6grp_total > 06      4grp_total > 63      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 769
1 2 3 4 range
A 1085.6
(3)
P 		542
(-1.4)
P 		590.2
(-1)
P 		346.5
(-3)
P 		739
B 912.7
(3)
P 		527
(-2.2)
P 		618.8
(-0.9)
P 		465.5
(-3)
P 		447
C 1058.7
(3)
P 		764.8
(0.6)
P 		694
(0.1)
P 		316.8
(-3)
P 		742
avr 1019
(3) 		611.3
(-0.8) 		634.3
(-0.6) 		376.3
(-3) 		643

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1490
1 2 3 4 5 6 range
A 694.8
(-0.3)
P 		983.6
(3)
P 		465.3
(-3)
P 		536.6
(-2.2)
P 		583.8
(-1.6)
P 		498.5
(-2.6)
P 		518
B 868
(3)
P 		864.7
(3)
P 		606.3
(-0.3)
P 		521
(-1.4)
P 		474
(-1.9)
P 		389.9
(-3)
P 		478
C 1879.4
(3)
P 		706
(-2)
P 		624.2
(-2.4)
P 		515.4
(-2.9)
P 		635.1
(-2.4)
P 		484.6
(-3)
P 		1395
avr 1147.4
(3) 		851.4
(0.4) 		565.3
(-2.1) 		524.3
(-2.4) 		564.3
(-2.1) 		457.7
(-3) 		690
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 345
1 2 3 4 range
A 395.3
(3)
P 		117.7
(-1.8)
P 		154.3
(-1.2)
P 		50.7
(-3)
P 		345
B 291
(3)
P 		130.2
(-2)
P 		143.4
(-1.6)
P 		99.2
(-3)
P 		192
C 350.4
(3)
P 		219.9
(0.4)
P 		241.9
(0.8)
P 		53.4
(-3)
P 		297
avr 345.6
(3) 		155.9
(-1.1) 		179.9
(-0.6) 		67.8
(-3) 		278

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 595
1 2 3 4 5 6 range
A 128.1
(-2.4)
P 		349.8
(3)
P 		101.3
(-3)
P 		136.1
(-2.2)
P 		176.2
(-1.2)
P 		121.4
(-2.5)
P 		249
B 302
(3)
P 		287.8
(2.5)
P 		147.2
(-2.7)
P 		138
(-3)
P 		192.6
(-1)
P 		145.4
(-2.7)
P 		164
C 696.6
(3)
P 		215.4
(-1.9)
P 		158.9
(-2.4)
P 		103.7
(-3)
P 		205.5
(-2)
P 		162.2
(-2.4)
P 		593
avr 375.6
(3) 		284.3
(0.8) 		135.8
(-2.8) 		125.9
(-3) 		191.4
(-1.4) 		143
(-2.6) 		250
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193458_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1247
Sequence Type Exemplar sequence
Representative Public ID C26C6.2 NCBI
Target Description C26C6.2 /REP_DB=WormBase Gene ID /WP=CE05311 /GEN=goa-1 /TR=Q18205 /GB=CAA96595.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=guanine nucleotide-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059707(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059707 NCBI Caenorhabditis elegans G protein,O, Alpha subunit family member (goa-1) (goa-1) mRNA, complete cds. 11/11 A 
SNAP00000003871 ENSEMBL cdna:SNAP chromosome:CEL140:I:7530338:7533983:1 11/11 None
GENEFINDER00000003879 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7530338:7533983:1 11/11 None
C26C6.2 ENSEMBL cdna:known chromosome:CEL140:I:7530244:7534842:1 gene:C26C6.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7530268-7533914(+) 100.0 100.0
Public Domain and Genome References
Gene Title guanine nucleotide-binding protein
Gene Symbol goa-1
Ensembl C26C6.2
Entrez Gene 172505 Entrez gene
SwissProt P51875 EMBL-EBI
WormBase CE05311 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.19360.1.S1_S_AT similar to Guanine nucleotide-binding protein G(o), alpha subunit 2 cfa
CANINE_2:CFAAFFX.14666.1.S1_AT similar to Guanine nucleotide-binding protein G(o), alpha subunit 2 cfa
DROSGENOME1:142441_AT G protein o 47A dm
DROSOPHILA_2:1632830_S_AT G protein o 47A dm
DROSGENOME1:151572_R_AT G protein o 47A dm
CHICKEN:GGAAFFX.25767.1.S1_AT similar to guanine nucleotide binding protein alpha oB gga
HG-U95AV2:34698_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95AV2:236_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HC-G110:236_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:204763_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A:204763_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A_2:204763_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:215912_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A_2:215912_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A:215912_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HU35KSUBD:RC_N80889_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HUGENEFL:M60165_CDS1_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:231951_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133B:231951_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:G10567815_3P_A_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.296184.0.S1_3P_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.296184.0.S1_3P_A_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.296184.1.S1_3P_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.198511.0.S1_3P_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A_2:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-FOCUS:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95AV2:34138_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95E:69489_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95E:90648_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95D:91782_F_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95D:91785_R_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133B:240328_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:240328_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.150495.0.A1_3P_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95D:80689_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
MG-U74AV2:103844_AT guanine nucleotide binding protein, alpha o mm
MOUSE430_2:1421152_A_AT guanine nucleotide binding protein, alpha o mm
MOE430A:1421152_A_AT guanine nucleotide binding protein, alpha o mm
MOUSE430A_2:1421152_A_AT guanine nucleotide binding protein, alpha o mm
MOUSE430A_2:1460383_AT guanine nucleotide binding protein, alpha o mm
MOUSE430_2:1460383_AT guanine nucleotide binding protein, alpha o mm
MOE430A:1460383_AT guanine nucleotide binding protein, alpha o mm
MU11KSUBA:M36778_S_AT guanine nucleotide binding protein, alpha o mm
MU11KSUBB:MSA.663.0_R_AT guanine nucleotide binding protein, alpha o mm
MU11KSUBB:MSA.663.0_S_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:100388_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:103843_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:161902_F_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:104414_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU11KSUBA:AA231554_F_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBA:TC18252_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBA:TC18252_G_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBB:TC28053_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBC:TC41585_S_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
RN-U34:M17526_G_AT guanine nucleotide binding protein, alpha o rn
RG-U34A:M17526_G_AT guanine nucleotide binding protein, alpha o rn
RN-U34:M17526_AT guanine nucleotide binding protein, alpha o rn
RG-U34A:M17526_AT guanine nucleotide binding protein, alpha o rn
RG-U34C:RC_AI227704_AT guanine nucleotide binding protein, alpha o rn
RAE230A:1368879_A_AT guanine nucleotide binding protein, alpha o rn
RAT230_2:1368879_A_AT guanine nucleotide binding protein, alpha o rn
RAE230A:1374314_AT Guanine nucleotide binding protein, alpha o rn
RAT230_2:1374314_AT Guanine nucleotide binding protein, alpha o rn
RG-U34B:RC_AA963891_AT Guanine nucleotide binding protein, alpha o rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4871 signal transducer activity inferred from electronic annotation QuickGO AmiGO
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA96595 Hypothetical protein C26C6.2 [Caenorhabditis elegans] ref|NP_492108.1| G protein,O, Alpha subunit family member (goa-1) [Caenorhabditis elegans] gb|AAG32093.1| heterotrimeric G protein alpha subunit [Caenorhabditis elegans] sp|P51875|GNAO_CAEEL Guanine nucleotide-binding protein G(o), alpha subunit 0.0
blast AAA28059 G-o protein alpha subunit 0.0
blast AAW02892 goa-1 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001019 EMBL-EBI Guanine nucleotide binding protein (G-protein), alpha subunit 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:193458_S_AT
gccaaatatttccttgacgacctggaaaggttaggagaggcaatatatcaaccaactgag
caagatattctccgaactcgtgtcaaaacaactggtattgttgaagttcacttcacattc
aaaaatctcaatttcaaattgttcgatgtgggaggtcaaagatcagaaaggaagaagtgg
attcattgtttcgaagatgttactgctattattttctgtgttgccatgtcagagtatgat
caagtgttgcacgaagatgagacaacaaaccgaatgcacgaatcgctgaagctgttcgat
tcgatctgtaataacaaatggttcacagatacatcgattattctgttcctgaacaagaag
gatctgtttgaagagaaaatcaagaaaagcccgttaacgatctgcttcccagaatattca
ggacgacaagactaccacgaggcatctgcgtatattcaagcacaatttgaggctaaaaac
aaatcagcgaataaggaaatctattgccacatgacatgtgccacagacacaactaacatt
caatttgtgtttgacgctgtcaccgatgtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCCAAATATTTCCTTGACGACCTGG 550 275 469 Antisense
GCAAGATATTCTCCGAACTCGTGTC 433 321 528 Antisense
CTGCTATTATTTTCTGTGTTGCCAT 10 239 671 Antisense
AATGCACGAATCGCTGAAGCTGTTC 268 165 741 Antisense
GAAGCTGTTCGATTCGATCTGTAAT 596 343 756 Antisense
GATACATCGATTATTCTGTTCCTGA 542 423 796 Antisense
GAAAAGCCCGTTAACGATCTGCTTC 546 353 852 Antisense
GACAAGACTACCACGAGGCATCTGC 394 365 893 Antisense
GAGGCATCTGCGTATATTCAAGCAC 385 405 907 Antisense
TGCCACAGACACAACTAACATTCAA 392 587 987 Antisense
TGTGTTTGACGCTGTCACCGATGTG 343 551 1014 Antisense
Sequence Source Affymetrix Proprietary Database