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[193447_at] noninactivating potassium channel (weak)

Description C03F11.1 /REP_DB=WormBase Gene ID /WP=CE03913 /TR=SW:Q11122 /GB=AAK18882.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=noninactivating potassium channel (weak)
Cluster 6grp_high1_10_10 > 24      4grp_high_8_8 > 09      6grp_total > 02      4grp_total > 23      6grp_high1_sub > 02      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 82
1 2 3 4 range
A 118
(3)
P 		46.4
(-2.9)
P 		44.9
(-3)
A 		104.8
(1.9)
P 		73
B 108.3
(3)
P 		40
(-3)
A 		44.7
(-2.6)
M 		64.3
(-0.9)
A 		68
C 98.8
(3)
P 		53.9
(-1.3)
A 		35.7
(-3)
P 		94.9
(2.6)
P 		63
avr 108.4
(3) 		46.8
(-2.5) 		41.8
(-3) 		88
(1.2) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 106
1 2 3 4 5 6 range
A 97
(3)
P 		94.4
(2.7)
P 		64.1
(-1.3)
A 		51.5
(-3)
A 		86.2
(1.6)
P 		53.6
(-2.7)
P 		46
B 119
(1.7)
P 		142.1
(3)
P 		71.3
(-1)
P 		60.6
(-1.6)
P 		100.7
(0.7)
P 		36.1
(-3)
M 		106
C 68.4
(-1.6)
P 		98.2
(3)
P 		70.5
(-1.2)
A 		68.3
(-1.6)
P 		59
(-3)
P 		63.6
(-2.3)
P 		39
avr 94.8
(1.3) 		111.6
(3) 		68.6
(-1.3) 		60.1
(-2.1) 		82
(0.1) 		51.1
(-3) 		61
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 43
(3)
P 		10.1
(-3)
P 		11.7
(-2.7)
A 		15.3
(-2.1)
P 		33
B 34.5
(3)
P 		9.9
(-3)
A 		10.4
(-2.9)
M 		13.7
(-2.1)
A 		25
C 32.7
(3)
P 		15.5
(-2.1)
A 		12.5
(-3)
P 		16
(-2)
P 		20
avr 36.7
(3) 		11.8
(-2.9) 		11.5
(-3) 		15
(-2.2) 		25

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 34
1 2 3 4 5 6 range
A 17.9
(-1.6)
P 		33.6
(3)
P 		14
(-2.7)
A 		13.1
(-3)
A 		26
(0.8)
P 		13
(-3)
P 		21
B 41.4
(2)
P 		47.3
(3)
P 		17.3
(-2.3)
P 		16.1
(-2.5)
P 		40.9
(1.9)
P 		13.5
(-3)
M 		34
C 25.4
(1.3)
P 		30
(3)
P 		17.9
(-1.5)
A 		13.7
(-3)
P 		19.1
(-1)
P 		21.3
(-0.2)
P 		16
avr 28.2
(0.7) 		37
(3) 		16.4
(-2.4) 		14.3
(-3) 		28.7
(0.8) 		15.9
(-2.6) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193447_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17156
Sequence Type Exemplar sequence
Representative Public ID C03F11.1 NCBI
Target Description C03F11.1 /REP_DB=WormBase Gene ID /WP=CE03913 /TR=SW:Q11122 /GB=AAK18882.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=noninactivating potassium channel (weak)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076516(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076516 NCBI Caenorhabditis elegans C03F11.1 (C03F11.1) mRNA, complete cds. 11/11 None
GENEFINDER00000029110 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:5384735:5394295:1 11/11 None
SNAP00000029100 ENSEMBL cdna:SNAP chromosome:CEL140:X:5391294:5394199:1 11/11 None
C03F11.1 ENSEMBL cdna:known chromosome:CEL140:X:5390695:5394105:1 gene:C03F11.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:5390695-5394106(+) 100.0 100.0
Public Domain and Genome References
Gene Title noninactivating potassium channel (weak)
Ensembl C03F11.1
Entrez Gene 182164 Entrez gene
SwissProt Q11122 EMBL-EBI
WormBase CE03913 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5516 calmodulin binding inferred from electronic annotation QuickGO AmiGO
15269 calcium-activated potassium channel activity inferred from electronic annotation QuickGO AmiGO
16286 small conductance calcium-activated potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK18882 Hypothetical protein C03F11.1 [Caenorhabditis elegans] ref|NP_508917.1| C03F11.1 [Caenorhabditis elegans] sp|Q11122|YX11_CAEEL Hypothetical protein C03F11.1 in chromosome X 0.0
blast CAE68746 Hypothetical protein CBG14678 [Caenorhabditis briggsae] 0.0
blast AAK18882 Hypothetical protein C03F11.1 [Caenorhabditis elegans] ref|NP_508917.1| C03F11.1 [Caenorhabditis elegans] sp|Q11122|YX11_CAEEL Hypothetical protein C03F11.1 in chromosome X 1.0E-174
blast CAE68746 Hypothetical protein CBG14678 [Caenorhabditis briggsae] 1.0E-159
blast CAA21625 Hypothetical protein B0399.1a [Caenorhabditis elegans] emb|CAB03807.2| Hypothetical protein B0399.1a [Caenorhabditis elegans] ref|NP_507800.2| B0399.1a [Caenorhabditis elegans] 3.0E-74
blast CAA21625 Hypothetical protein B0399.1a [Caenorhabditis elegans] emb|CAB03807.2| Hypothetical protein B0399.1a [Caenorhabditis elegans] ref|NP_507800.2| B0399.1a [Caenorhabditis elegans] 5.0E-73
Protein Domains
Database ID Description E-Value
Pfam IPR003931 EMBL-EBI Calcium-activated SK potassium channel 2.4E-23
Pfam IPR004178 EMBL-EBI Calmodulin binding domain 1.2E-45
Pfam IPR003931 EMBL-EBI Calcium-activated SK potassium channel 2.4E-23
Pfam IPR004178 EMBL-EBI Calmodulin binding domain 1.2E-45
Pfam IPR003931 EMBL-EBI Calcium-activated SK potassium channel 8.4E-23
Pfam IPR004178 EMBL-EBI Calmodulin binding domain 1.2E-45
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508917.1 5 78-97,112-134,264-283,298-320,327-349
C03F11.1 5 78-97,112-134,264-283,298-320,327-349
GENEFINDER00000029110 3 616-638,651-670,680-702
SNAP00000029100 5 13-35,55-77,182-201,216-238,245-267
Sequence
Target Sequence 
>C. ELEGANS:193447_AT
gaacccgcaatcaattttgtactcgaattctctgtggttcattgctatcaccttcatgtt
aaatggttatggagatattgtgccacagacaaatgcggggagatttattgcaatctttgt
tggagttgtgggagccgtaatttcttcgatcttaattgcggttatatccaggaacattct
tctttctcaaggacaaagaaacgtgaataactttatgtacgacagcaaattagccagaga
gcacaaggaagcagccgcgcgagttctacaacacacatggcacattcataaatgtctaca
agggagtgacggtggaaatcgacggctgcgaacttatcagaggaagtttctgaaagcaat
tcacaaattccgttctgtaaaaagtgagatgcgagaattttccgagaacaacagtcaaaa
caaccctcaaatgacccggcttgtaactgatatgcac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACCCGCAATCAATTTTGTACTCG 214 347 891 Antisense
ACTCGAATTCTCTGTGGTTCATTGC 373 99 911 Antisense
GTTCATTGCTATCACCTTCATGTTA 151 445 927 Antisense
GTGGGAGCCGTAATTTCTTCGATCT 573 487 1018 Antisense
GGAACATTCTTCTTTCTCAAGGACA 176 529 1061 Antisense
GCGCGAGTTCTACAACACACATGGC 271 287 1147 Antisense
AGTGACGGTGGAAATCGACGGCTGC 323 59 1195 Antisense
TCGACGGCTGCGAACTTATCAGAGG 643 601 1209 Antisense
AGCAATTCACAAATTCCGTTCTGTA 696 75 1245 Antisense
TCAAAACAACCCTCAAATGACCCGG 535 627 1305 Antisense
GACCCGGCTTGTAACTGATATGCAC 426 381 1323 Antisense
Sequence Source Affymetrix Proprietary Database