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[193429_at] PH (pleckstrin homology) domain

Description ZK897.1 /REP_DB=WormBase Gene ID /WP=CE27358 /GEN=unc-31 /TR=Q23658 /GB=CAA93520.3 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=PH (pleckstrin homology) domain
Cluster 6grp_total > 93      4grp_total > 0      6grp_cgc > 99      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 59
1 2 3 4 range
A 8.2
(3)
A 		2.3
(-3)
A 		7.8
(2.6)
A 		4.8
(-0.5)
A 		6
B 6.3
(-2.6)
A 		3.5
(-3)
A 		9.9
(-2.1)
A 		48.6
(3)
A 		45
C 8.7
(-2.4)
A 		3.4
(-3)
A 		27.2
(-0.5)
A 		61
(3)
A 		58
avr 7.7
(-2.2) 		3.1
(-3) 		15
(-1) 		38.1
(3) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 53
1 2 3 4 5 6 range
A 10.8
(-2.1)
A 		2.7
(-3)
A 		2.5
(-3)
A 		7.8
(-2.4)
A 		55.5
(3)
A 		7
(-2.5)
A 		53
B 32.9
(3)
A 		9.8
(-2)
A 		6.1
(-2.8)
A 		7.7
(-2.4)
A 		23.5
(1)
A 		5
(-3)
A 		28
C 6.6
(-3)
A 		6.4
(-3)
A 		10.8
(-2.1)
A 		9.5
(-2.4)
A 		35.8
(3)
A 		10.1
(-2.2)
A 		29
avr 16.8
(-1) 		6.3
(-3) 		6.5
(-3) 		8.3
(-2.6) 		38.3
(3) 		7.4
(-2.8) 		32
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 3
(3)
A 		0.5
(-3)
A 		2
(0.6)
A 		0.7
(-2.5)
A 		3
B 2
(-2.3)
A 		0.9
(-3)
A 		2.3
(-2.1)
A 		10.3
(3)
A 		9
C 2.9
(-1.8)
A 		1
(-3)
A 		9.5
(2.5)
A 		10.3
(3)
A 		9
avr 2.6
(-1.3) 		0.8
(-3) 		4.6
(0.6) 		7.1
(3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 2
(-2.4)
A 		0.9
(-2.9)
A 		0.5
(-3)
A 		2
(-2.4)
A 		16.8
(3)
A 		1.7
(-2.6)
A 		16
B 11.4
(3)
A 		3.3
(-1.9)
A 		1.5
(-3)
A 		2
(-2.7)
A 		9.5
(1.8)
A 		1.9
(-2.8)
A 		10
C 2.5
(-2.6)
A 		1.9
(-3)
A 		2.7
(-2.5)
A 		1.9
(-3)
A 		11.6
(3)
A 		3.4
(-2.1)
A 		10
avr 5.3
(-1) 		2
(-2.8) 		1.6
(-3) 		2
(-2.8) 		12.6
(3) 		2.3
(-2.6) 		11
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193429_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9061
Sequence Type Exemplar sequence
Representative Public ID ZK897.1 NCBI
Target Description ZK897.1 /REP_DB=WormBase Gene ID /WP=CE27358 /GEN=unc-31 /TR=Q23658 /GB=CAA93520.3 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=PH (pleckstrin homology) domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070036(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070036 NCBI Caenorhabditis elegans UNCoordinated family member (unc-31) (unc-31) mRNA, complete cds. 11/11 None
SNAP00000024594 ENSEMBL cdna:SNAP chromosome:CEL140:IV:12781348:12787483:1 11/11 None
GENEFINDER00000024595 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:12780695:12787510:1 11/11 None
ZK897.1 ENSEMBL cdna:known chromosome:CEL140:IV:12776105:12786943:1 gene:ZK897.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:12776110-12786857(+) 99.87 100.0
Public Domain and Genome References
Gene Title PH (pleckstrin homology) domain
Gene Symbol unc-31
Ensembl ZK897.1
Entrez Gene 178233 Entrez gene
SwissProt Q23658 EMBL-EBI
WormBase CE36419 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.11508.1.S1_S_AT similar to Ca2+-dependent secretion activator isoform 3 cfa
CHICKEN:GGA.16126.1.S1_AT Ca2+-dependent secretion activator gga
CHICKEN:GGA.18393.1.S1_S_AT Ca2+-dependent secretion activator gga
CHICKEN:GGA.19608.1.S1_S_AT Ca2+-dependent secretion activator gga
CHICKEN:GGAAFFX.22193.1.S1_S_AT Ca2+-dependent secretion activator gga
CHICKEN:GGAAFFX.22193.2.S1_S_AT Ca2+-dependent secretion activator gga
CHICKEN:GGAAFFX.22193.4.S1_AT Ca2+-dependent secretion activator gga
CHICKEN:GGAAFFX.22193.4.S1_S_AT Ca2+-dependent secretion activator gga
CHICKEN:GGAAFFX.22193.5.S1_AT Ca2+-dependent secretion activator gga
CHICKEN:GGAAFFX.22193.6.S1_AT Ca2+-dependent secretion activator gga
HG-U95AV2:31848_AT Ca2+-dependent secretion activator hs
HG-U133_PLUS_2:204814_AT Ca2+-dependent secretion activator hs
HG-U133A:204814_AT Ca2+-dependent secretion activator hs
HG-FOCUS:204814_AT Ca2+-dependent secretion activator hs
HG-U133A_2:204814_AT Ca2+-dependent secretion activator hs
HG-U133_PLUS_2:234220_AT Ca2+-dependent secretion activator hs
HG-U133B:234220_AT Ca2+-dependent secretion activator hs
HU35KSUBC:RC_T03403_AT Ca2+-dependent secretion activator hs
HU35KSUBD:RC_Z38783_S_AT Ca2+-dependent secretion activator hs
HU35KSUBD:RC_D52692_S_AT Ca2+-dependent secretion activator hs
HUGENEFL:U36448_AT Ca2+-dependent secretion activator hs
U133_X3P:G4502540_3P_S_AT Ca2+-dependent secretion activator hs
U133_X3P:HS2.151301.5.S1_3P_S_AT Ca2+-dependent secretion activator hs
U133_X3P:HS.306685.0.A1_3P_AT Ca2+-dependent secretion activator hs
U133_X3P:HS.151301.1.S1_3P_AT Ca2+-dependent secretion activator hs
U133_X3P:HS.151301.1.S1_3P_A_AT Ca2+-dependent secretion activator hs
HG-U133_PLUS_2:1568603_AT Ca2+-dependent secretion activator hs
HG-U133_PLUS_2:1568604_A_AT Ca2+-dependent secretion activator hs
HG-U133_PLUS_2:233950_AT Ca2+-dependent secretion activator hs
HG-U133B:233950_AT Ca2+-dependent secretion activator hs
HG-U95C:52306_AT Ca2+-dependent secretion activator hs
HG-U95D:91497_AT Ca2+-dependent secretion activator hs
HG-U133_PLUS_2:234593_AT Ca2+-dependent secretion activator hs
HG-U133B:234593_AT Ca2+-dependent secretion activator hs
U133_X3P:HS.306685.0.S1_3P_AT Ca2+-dependent secretion activator hs
HG-U133_PLUS_2:236697_AT Ca2+-dependent secretion activator hs
HG-U133B:236697_AT Ca2+-dependent secretion activator hs
HG-U95B:44758_AT Ca2+-dependent secretion activator hs
HG-U95B:54592_AT Ca2+-dependent secretion activator hs
HG-U95D:77084_AT Ca2+-dependent secretion activator hs
HG-U95D:78474_AT Ca2+-dependent secretion activator hs
HU35KSUBB:RC_F10211_AT Ca2+-dependent secretion activator hs
HU35KSUBB:RC_R49025_AT Ca2+-dependent secretion activator hs
U133_X3P:HS.7990.0.A1_3P_AT Ca2+-dependent secretion activator hs
MOUSE430A_2:1448955_S_AT Ca<2+>dependent activator protein for secretion mm
MOE430A:1448955_S_AT Ca<2+>dependent activator protein for secretion mm
MOUSE430_2:1448955_S_AT Ca<2+>dependent activator protein for secretion mm
MU11KSUBA:D86214_S_AT Ca<2+>dependent activator protein for secretion mm
MG-U74AV2:92988_I_AT Ca<2+>dependent activator protein for secretion mm
MG-U74AV2:92989_F_AT Ca<2+>dependent activator protein for secretion mm
MG-U74BV2:108947_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
MG-U74CV2:137730_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
MOE430B:1444488_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
MOUSE430_2:1444488_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
MOE430B:1445586_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
MOUSE430_2:1445586_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
MOE430B:1458298_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
MOUSE430_2:1458298_AT Ca<2+>dependent activator protein for secretion (Cadps), mRNA mm
RG-U34A:U16802_AT Ca<2+-dependent activator protein for secretion rn
RAE230A:1368523_AT Ca<2+-dependent activator protein for secretion rn
RAT230_2:1368523_AT Ca<2+-dependent activator protein for secretion rn
RAE230B:1390754_AT Ca<2+-dependent activator protein for secretion rn
RAT230_2:1390754_AT Ca<2+-dependent activator protein for secretion rn
Protein Similarities
Method ID Description E-Value
blast CAA93520 Hypothetical protein ZK897.1 [Caenorhabditis elegans] ref|NP_502437.2| UNCoordinated family member (unc-31) [Caenorhabditis elegans] 0.0
blast CAE74552 Hypothetical protein CBG22310 [Caenorhabditis briggsae] 0.0
blast NP_037351 Ca<2+-dependent activator protein for secretion [Rattus norvegicus] gb|AAB88635.1| Ca2+-dependent activator protein; calcium-dependent actin-binding protein [Rattus norvegicus] pir||I84505 calcium-dependent actin-binding protein - rat 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR010439 EMBL-EBI Protein of unknown function DUF1041 2.2E-74
Pfam IPR000008 EMBL-EBI C2 domain 4.3E-4
Pfam IPR001849 EMBL-EBI Pleckstrin-like 3.3E-12
Pfam IPR010439 EMBL-EBI Protein of unknown function DUF1041 2.2E-74
Pfam IPR001849 EMBL-EBI Pleckstrin-like 3.3E-12
Pfam IPR010439 EMBL-EBI Protein of unknown function DUF1041 2.2E-74
Pfam IPR001849 EMBL-EBI Pleckstrin-like 1.8E-12
Sequence
Target Sequence 
>C. ELEGANS:193429_AT
ccttcaccgcattcgacagttggatgcaacgagccaaaaagtccaccgattacatgcttc
catcagaagtttgcgtgcaaatcaacgtaatgttcagctcaaagagccgtgctgttcgag
tcactgttgattctggagaatacaaatatcagtcaaaactcgacgaaactctggagacaa
tgctcaaaactatggaatcatgtattcaagagaaacttcacggagttcttgaatcacgtc
aacctctgactgctcaacaatcatcagggcaaatcggaaattcatatgttacatttttcc
acggatgcactgaacttcttcgacaagttattatcgatgaaatttgggttaatgggctct
tcgagcattggtacgacaaccaaatgaaatcaatcaatgaatggttgacagaacgtcttc
aacaatcgttgagtgcaactcaatacatttccctttcgacaattgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCTTCACCGCATTCGACAGTTGGAT 291 269 3221 Antisense
GCAACGAGCCAAAAAGTCCACCGAT 189 319 3246 Antisense
CACCGATTACATGCTTCCATCAGAA 360 201 3264 Antisense
AGCTCAAAGAGCCGTGCTGTTCGAG 478 79 3316 Antisense
GCTGTTCGAGTCACTGTTGATTCTG 492 295 3331 Antisense
TGAATCACGTCAACCTCTGACTGCT 576 575 3450 Antisense
TTCCACGGATGCACTGAACTTCTTC 55 701 3517 Antisense
ATTTGGGTTAATGGGCTCTTCGAGC 219 9 3562 Antisense
GGGCTCTTCGAGCATTGGTACGACA 494 491 3574 Antisense
GAGTGCAACTCAATACATTTCCCTT 204 401 3651 Antisense
AATACATTTCCCTTTCGACAATTGT 458 171 3662 Antisense
Sequence Source Affymetrix Proprietary Database