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[193425_at] metatrophic glutamate receptor

Description ZC506.4 /REP_DB=WormBase Gene ID /WP=CE01682 /GEN=mgl-1 /TR=SW:Q09630 /GB=CAA87374.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=metatrophic glutamate receptor
Cluster 6grp_total > 16      4grp_total > 38      6grp_cgc > 23      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 280
1 2 3 4 range
A 326.3
(3)
P 		141.7
(-3)
A 		165.4
(-2.2)
A 		180
(-1.8)
P 		185
B 353
(3)
P 		230.2
(-0.1)
A 		118
(-3)
A 		233.6
(-0)
P 		235
C 398.2
(3)
P 		160.6
(-2.1)
A 		121
(-3)
A 		285.2
(0.6)
P 		277
avr 359.2
(3) 		177.5
(-1.9) 		134.8
(-3) 		232.9
(-0.4) 		224

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 218
1 2 3 4 5 6 range
A 247
(3)
A 		223.6
(1.9)
A 		154
(-1.3)
A 		151.2
(-1.4)
A 		117.2
(-3)
A 		188.4
(0.3)
A 		130
B 251.6
(3)
A 		205
(0.6)
A 		177.1
(-0.8)
A 		135.4
(-3)
A 		148
(-2.3)
A 		149.1
(-2.3)
A 		116
C 335.2
(3)
P 		282.4
(1.4)
A 		175.5
(-1.7)
A 		163.2
(-2.1)
A 		136.2
(-2.9)
A 		131.8
(-3)
A 		203
avr 277.9
(3) 		237
(1.3) 		168.9
(-1.5) 		149.9
(-2.3) 		133.8
(-3) 		156.4
(-2.1) 		144
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 105
1 2 3 4 range
A 118.8
(3)
P 		30.8
(-2.7)
A 		43.2
(-1.9)
A 		26.4
(-3)
P 		92
B 112.6
(3)
P 		56.9
(-0.9)
A 		27.4
(-3)
A 		49.8
(-1.4)
P 		85
C 131.8
(3)
P 		46.2
(-2.7)
A 		42.2
(-3)
A 		48.1
(-2.6)
P 		90
avr 121.1
(3) 		44.6
(-2.5) 		37.6
(-3) 		41.4
(-2.7) 		84

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 91
1 2 3 4 5 6 range
A 45.5
(-1.4)
A 		79.5
(3)
A 		33.5
(-3)
A 		38.3
(-2.4)
A 		35.4
(-2.8)
A 		45.9
(-1.4)
A 		46
B 87.5
(3)
A 		68.2
(0.8)
A 		43
(-2.2)
A 		35.9
(-3)
A 		60.1
(-0.2)
A 		55.6
(-0.7)
A 		52
C 124.2
(3)
P 		86.2
(0.5)
A 		44.7
(-2.2)
A 		32.8
(-3)
A 		44.1
(-2.3)
A 		44.1
(-2.3)
A 		91
avr 85.7
(3) 		78
(2.1) 		40.4
(-2.4) 		35.7
(-3) 		46.5
(-1.7) 		48.5
(-1.5) 		50
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193425_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16394
Sequence Type Exemplar sequence
Representative Public ID ZC506.4 NCBI
Target Description ZC506.4 /REP_DB=WormBase Gene ID /WP=CE01682 /GEN=mgl-1 /TR=SW:Q09630 /GB=CAA87374.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=metatrophic glutamate receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077273(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077273 NCBI Caenorhabditis elegans Metabotropic GLutamate receptor family member (mgl-1) (mgl-1) mRNA, complete cds. 11/11 None
GENEFINDER00000023347 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:9968559:9976322:-1 11/11 None
ZC506.4 ENSEMBL cdna:known chromosome:CEL140:X:9968559:9974332:-1 gene:ZC506.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000023346 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:9968558-9974332(-) 100.0 100.0
Public Domain and Genome References
Gene Title metatrophic glutamate receptor
Gene Symbol mgl-1
Ensembl ZC506.4
Entrez Gene 191707 Entrez gene
SwissProt Q09630 EMBL-EBI
WormBase CE01682 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1639492_AT Metabotropic glutamate receptor dm
DROSGENOME1:143909_AT Metabotropic glutamate receptor dm
CHICKEN:GGAAFFX.4097.1.S1_AT similar to Metabotropic glutamate receptor 3 precursor (mGluR3) gga
HG-U133_PLUS_2:205814_AT glutamate receptor, metabotropic 3 hs
HG-U133A_2:205814_AT glutamate receptor, metabotropic 3 hs
HG-U133A:205814_AT glutamate receptor, metabotropic 3 hs
HG-FOCUS:205814_AT glutamate receptor, metabotropic 3 hs
HU35KSUBC:RC_F01525_F_AT glutamate receptor, metabotropic 3 hs
HU35KSUBD:RC_N62328_S_AT glutamate receptor, metabotropic 3 hs
HUGENEFL:X77748_AT glutamate receptor, metabotropic 3 hs
U133_X3P:G4504138_3P_AT glutamate receptor, metabotropic 3 hs
HG-U95AV2:39928_AT glutamate receptor, metabotropic 3 hs
HG-U133_PLUS_2:239480_AT Glutamate receptor, metabotropic 3 hs
HG-U133B:239480_AT Glutamate receptor, metabotropic 3 hs
HG-U133_PLUS_2:240004_AT Glutamate receptor, metabotropic 3 hs
HG-U133B:240004_AT Glutamate receptor, metabotropic 3 hs
HG-U133_PLUS_2:242221_AT Glutamate receptor, metabotropic 3 hs
HG-U133B:242221_AT Glutamate receptor, metabotropic 3 hs
HG-U95B:42496_AT Glutamate receptor, metabotropic 3 hs
HG-U95C:52118_AT Glutamate receptor, metabotropic 3 hs
HG-U95C:56140_AT Glutamate receptor, metabotropic 3 hs
HG-U95D:90530_AT Glutamate receptor, metabotropic 3 hs
U133_X3P:HS.127122.0.A1_3P_AT Glutamate receptor, metabotropic 3 hs
HU35KSUBB:RC_T91849_AT Glutamate receptor, metabotropic 3 hs
HU35KSUBD:RC_AA608964_AT Glutamate receptor, metabotropic 3 hs
U133_X3P:HS.112621.0.A1_3P_AT Glutamate receptor, metabotropic 3 hs
U133_X3P:HS.16941.0.A1_3P_AT Glutamate receptor, metabotropic 3 hs
MG-U74BV2:164178_I_AT glutamate receptor, metabotropic 3 mm
MOE430B:1430136_AT glutamate receptor, metabotropic 3 mm
MOUSE430_2:1430136_AT glutamate receptor, metabotropic 3 mm
RN-U34:M92076_AT glutamate receptor, metabotropic 3 rn
RG-U34A:M92076_AT glutamate receptor, metabotropic 3 rn
RAE230A:1388189_AT glutamate receptor, metabotropic 3 rn
RAT230_2:1388189_AT glutamate receptor, metabotropic 3 rn
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8067 metabotropic glutamate, GABA-B-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA87374 Hypothetical protein ZC506.4 [Caenorhabditis elegans] ref|NP_509674.1| Metabotropic GLutamate receptor family member (mgl-1) [Caenorhabditis elegans] sp|Q09630|MGR1_CAEEL Probable metabotropic glutamate receptor mgl-1 0.0
blast CAE58757 Hypothetical protein CBG01949 [Caenorhabditis briggsae] 0.0
blast AAF59402 CG11144-PA [Drosophila melanogaster] ref|NP_524639.2| CG11144-PA [Drosophila melanogaster] sp|P91685|MGR_DROME Metabotropic glutamate receptor precursor 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000337 EMBL-EBI G-protein coupled receptor family 3, metabotropic glutamate receptor-like 1.0E-126
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 1.4E-63
Pfam IPR000337 EMBL-EBI G-protein coupled receptor family 3, metabotropic glutamate receptor-like 1.0E-126
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 4.9E-65
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509674.1 7 684-706,719-738,753-772,792-814,838-857,870-892,907-929
ZC506.4 7 684-706,719-738,753-772,792-814,838-857,870-892,907-929
GENEFINDER00000023347 7 668-690,703-722,737-756,776-798,822-841,854-876,891-913
Sequence
Target Sequence 
>C. ELEGANS:193425_AT
ggttgtcatgactgcaatgctagccggagtacaattgatcggaagtcttatttggctgtc
agtagtgccaccaggttggagacaccactaccccaccagggaccaggtggttttaacttg
taatgttcctgaccatcactttttgtattcattggcttatgatggtttcctgattgtgct
ttgtacaacgtatgctgtaaaaactagaaaagtgcccgaaaatttcaacgagacaaaatt
catcggcttctccatgtacacgacatgtgttgtttggctcagttggattttctttttttt
tggaaccggaagtgatttccaaattcaaacatcatctctttgtatttcaatttccatgtc
agccaatgtggcattagcatgcatattttcaccaaagctttggatcattttgtttgaaaa
acacaaaaacgtccgaaagcaggaaggtgaaagtatgcttaacaaaagtagcagatcatt
aggaaactgtagttcccgattatgtgccaatagcatcgacgagccaaatcagtacaccgc
tttgctcactgacagtacacgaagacgatcatcacgcaagacatctcagcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTTGTCATGACTGCAATGCTAGCC 674 507 2385 Antisense
AGTGCCACCAGGTTGGAGACACCAC 329 59 2448 Antisense
TAATGTTCCTGACCATCACTTTTTG 663 635 2505 Antisense
GATGGTTTCCTGATTGTGCTTTGTA 80 409 2545 Antisense
ACAAAATTCATCGGCTTCTCCATGT 168 113 2617 Antisense
GTTTGGCTCAGTTGGATTTTCTTTT 60 453 2656 Antisense
GTATTTCAATTTCCATGTCAGCCAA 373 453 2726 Antisense
ACTGTAGTTCCCGATTATGTGCCAA 51 97 2870 Antisense
GAGCCAAATCAGTACACCGCTTTGC 24 385 2905 Antisense
CCGCTTTGCTCACTGACAGTACACG 456 263 2921 Antisense
GATCATCACGCAAGACATCTCAGCC 187 421 2951 Antisense
Sequence Source Affymetrix Proprietary Database