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[193415_at] fork-head domain-type transcription factors

Description F26B1.7 /REP_DB=WormBase Gene ID /WP=CE28006 /TR=P91278 /GB=AAB37792.2 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=fork-head domain-type transcription factors
Cluster 6grp_total > 25      4grp_total > 45      6grp_cgc > 33      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 127
1 2 3 4 range
A 95.9
(-1.5)
A 		168.5
(3)
A 		71.1
(-3)
A 		115.1
(-0.3)
A 		97
B 120.4
(3)
A 		50.2
(-3)
A 		63.8
(-1.8)
A 		61.9
(-2)
A 		70
C 92.8
(3)
A 		52
(-1.7)
A 		76.6
(1.1)
A 		41.2
(-3)
A 		52
avr 103
(3) 		90.2
(0.6) 		70.5
(-3) 		72.7
(-2.6) 		33

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 105
1 2 3 4 5 6 range
A 83.8
(1.9)
A 		99
(3)
A 		60
(0.1)
A 		18.5
(-3)
A 		56.6
(-0.2)
A 		20
(-2.9)
A 		81
B 102.5
(3)
A 		73.1
(0.8)
A 		25.5
(-2.8)
A 		37.7
(-1.9)
A 		22.6
(-3)
A 		39.8
(-1.7)
A 		80
C 111.5
(3)
A 		105.2
(2.6)
A 		91.4
(1.8)
A 		6.8
(-3)
A 		32.9
(-1.5)
A 		64.6
(0.3)
A 		105
avr 99.3
(3) 		92.4
(2.5) 		59
(-0.1) 		21
(-3) 		37.4
(-1.7) 		41.5
(-1.4) 		78
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 31
1 2 3 4 range
A 34.9
(2.5)
A 		36.6
(3)
A 		18.6
(-2.5)
A 		16.8
(-3)
A 		20
B 38.4
(3)
A 		12.4
(-3)
A 		14.8
(-2.4)
A 		13.2
(-2.8)
A 		26
C 30.7
(3)
A 		14.9
(-1)
A 		26.7
(2)
A 		7
(-3)
A 		24
avr 34.7
(3) 		21.3
(-0.6) 		20
(-0.9) 		12.3
(-3) 		22

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 40
1 2 3 4 5 6 range
A 15.4
(-0.9)
A 		35.2
(3)
A 		13.1
(-1.3)
A 		4.7
(-3)
A 		17.1
(-0.6)
A 		4.9
(-3)
A 		31
B 35.7
(3)
A 		24.3
(0.7)
A 		6.2
(-3)
A 		10
(-2.2)
A 		9.2
(-2.4)
A 		14.8
(-1.3)
A 		30
C 41.3
(3)
A 		32.1
(1.6)
A 		23.3
(0.3)
A 		1.4
(-3)
A 		10.7
(-1.6)
A 		21.6
(0)
A 		40
avr 30.8
(3) 		30.5
(2.9) 		14.2
(-0.9) 		5.4
(-3) 		12.3
(-1.4) 		13.8
(-1) 		25
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193415_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1336
Sequence Type Exemplar sequence
Representative Public ID F26B1.7 NCBI
Target Description F26B1.7 /REP_DB=WormBase Gene ID /WP=CE28006 /TR=P91278 /GB=AAB37792.2 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=fork-head domain-type transcription factors
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059425(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059425 NCBI Caenorhabditis elegans LEThal family member (let-381) (let-381) mRNA, complete cds. 11/11 A 
GENEFINDER00000041722 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6328560:6334828:-1 11/11 None
SNAP00000041717 ENSEMBL cdna:SNAP chromosome:CEL140:I:6330697:6332118:-1 11/11 None
F26B1.7 ENSEMBL cdna:known chromosome:CEL140:I:6328560:6332118:-1 gene:F26B1.7 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6330625-6332047(-) 100.0 100.0
Public Domain and Genome References
Gene Title fork-head domain-type transcription factors
Gene Symbol let-381
Ensembl F26B1.7
Entrez Gene 172331 Entrez gene
SwissProt P91278 EMBL-EBI
WormBase CE28006 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_491826 LEThal family member (let-381) [Caenorhabditis elegans] gb|AAB37792.2| Lethal protein 381 [Caenorhabditis elegans] 1.0E-178
blast NP_491826 LEThal family member (let-381) [Caenorhabditis elegans] gb|AAB37792.2| Lethal protein 381 [Caenorhabditis elegans] 1.0E-176
blast CAE67163 Hypothetical protein CBG12589 [Caenorhabditis briggsae] 1.0E-109
blast NP_491826 LEThal family member (let-381) [Caenorhabditis elegans] gb|AAB37792.2| Lethal protein 381 [Caenorhabditis elegans] 1.0E-82
blast CAE67163 Hypothetical protein CBG12589 [Caenorhabditis briggsae] 2.0E-60
blast CAF98088 unnamed protein product [Tetraodon nigroviridis] 1.0E-30
Protein Domains
Database ID Description E-Value
scop a.4.5.Forkhead DNA-binding domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; Forkhead DNA-binding domain 8.00000014402008E-35
scop a.4.5.Forkhead DNA-binding domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; Forkhead DNA-binding domain 1.0000000467011E-34
scop a.4.5.Forkhead DNA-binding domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; Forkhead DNA-binding domain 2.0000000934022E-34
Pfam IPR001766 EMBL-EBI Fork head transcription factor 1.7E-40
Pfam IPR001766 EMBL-EBI Fork head transcription factor 1.7E-40
Sequence
Target Sequence 
>C. ELEGANS:193415_AT
aatttattctcttgccaatgctctgggtccactgaaattggatagtactgctccaaacaa
ttcgcatcgtacaattaaagctgaaaactactttaatgaggatgaggaagattacaatga
gaactcgcatgaagattcggaagattcaaaagaagacagtgatggacaaggatgtagatc
aagaaaaagaaaagagaaaccaccattttcttatattgctttgattgctatggctatttc
aaagcgtccggacaaaaaggcaacattggctgaaatttacagttatcttcaggaaaactt
tgaattttttcgtggagaatacgctggatggcggaactctattcgccacaatttgagctt
aaacgaatgcttcgttaagttgccaaaagatactggagagagttatcgtggtcgtaaggg
tcataagtggacaatcagtgattcatgtgagttcatgttggaggaaaacggattccgtcg
tcgtccacgtggatacaaggccagaaagagaactcattttccgggagtcactgcgagcaa
t

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATTTATTCTCTTGCCAATGCTCTG 227 175 30 Antisense
CCAATGCTCTGGGTCCACTGAAATT 48 277 44 Antisense
GTACTGCTCCAAACAATTCGCATCG 468 459 74 Antisense
ATATTGCTTTGATTGCTATGGCTAT 41 19 242 Antisense
ATGGCTATTTCAAAGCGTCCGGACA 480 51 259 Antisense
GAATACGCTGGATGGCGGAACTCTA 117 325 346 Antisense
CGGAACTCTATTCGCCACAATTTGA 266 243 361 Antisense
GAATGCTTCGTTAAGTTGCCAAAAG 162 331 394 Antisense
GAGTTATCGTGGTCGTAAGGGTCAT 296 395 429 Antisense
GTCGTCGTCCACGTGGATACAAGGC 311 471 506 Antisense
TTTTCCGGGAGTCACTGCGAGCAAT 528 677 546 Antisense
Sequence Source Affymetrix Proprietary Database