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[193389_at] Leucine Rich Repeat (2 copies) (2 domains)

Description C33A12.12 /REP_DB=WormBase Gene ID /WP=CE15665 /TR=Q18367 /GB=CAB16465.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies) (2 domains)
Cluster 6grp_total > 67      4grp_total > 18      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 66
1 2 3 4 range
A 3
(-2.6)
A 		10
(3)
A 		5.8
(-0.4)
A 		2.5
(-3)
A 		8
B 4.5
(-1.2)
A 		9.3
(3)
A 		6.1
(0.2)
A 		2.4
(-3)
A 		7
C 12
(-2.4)
A 		10.8
(-2.5)
A 		5.7
(-3)
A 		68.1
(3)
A 		62
avr 6.5
(-2.8) 		10
(-1.7) 		5.9
(-3) 		24.3
(3) 		18

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 47
1 2 3 4 5 6 range
A 4.7
(-1.5)
A 		4
(-2.1)
A 		10.2
(3)
A 		2.9
(-3)
A 		3.4
(-2.6)
A 		8.8
(1.8)
A 		7
B 7.2
(-2.5)
A 		3.9
(-2.9)
A 		3.7
(-3)
A 		3.5
(-3)
A 		6.4
(-2.6)
A 		49
(3)
A 		46
C 2.1
(-3)
A 		3.2
(-2.6)
A 		5.8
(-1.8)
A 		9
(-0.7)
A 		3.9
(-2.4)
A 		20.2
(3)
A 		18
avr 4.7
(-2.7) 		3.7
(-3) 		6.6
(-2.2) 		5.1
(-2.6) 		4.6
(-2.8) 		26
(3) 		22
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 1.1
(-0.7)
A 		2.2
(3)
A 		1.5
(0.7)
A 		0.4
(-3)
A 		2
B 1.4
(0)
A 		2.3
(3)
A 		1.4
(0)
A 		0.5
(-3)
A 		2
C 4
(-1.7)
A 		3.1
(-2.3)
A 		2
(-3)
A 		11.5
(3)
A 		10
avr 2.2
(-1.6) 		2.5
(-0.8) 		1.6
(-3) 		4.1
(3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 18
1 2 3 4 5 6 range
A 0.9
(-2.2)
A 		1.4
(-0.2)
A 		2.2
(3)
A 		0.7
(-3)
A 		1
(-1.8)
A 		2.1
(2.6)
A 		2
B 2.5
(-2.4)
A 		1.3
(-2.9)
A 		0.9
(-3)
A 		0.9
(-3)
A 		2.6
(-2.4)
A 		18.3
(3)
A 		17
C 0.8
(-3)
A 		1
(-2.8)
A 		1.5
(-2.3)
A 		1.8
(-2)
A 		1.2
(-2.6)
A 		6.7
(3)
A 		6
avr 1.4
(-2.8) 		1.2
(-2.9) 		1.5
(-2.7) 		1.1
(-3) 		1.6
(-2.6) 		9
(3) 		8
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193389_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10126
Sequence Type Exemplar sequence
Representative Public ID C33A12.12 NCBI
Target Description C33A12.12 /REP_DB=WormBase Gene ID /WP=CE15665 /TR=Q18367 /GB=CAB16465.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies) (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069273(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069273 NCBI Caenorhabditis elegans C33A12.12 (C33A12.12) mRNA, complete cds. 11/11 None
C33A12.12 ENSEMBL cdna:known chromosome:CEL140:IV:9482047:9485060:-1 gene:C33A12.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9482052-9485066(-) 98.95 100.0
Public Domain and Genome References
Gene Title Leucine Rich Repeat (2 copies) (2 domains)
Ensembl C33A12.12
Entrez Gene 177782 Entrez gene
SwissProt Q18367 EMBL-EBI
WormBase CE15665 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA92801 Hypothetical protein C33A12.12 [Caenorhabditis elegans] emb|CAA22147.1| Hypothetical protein C33A12.12 [Caenorhabditis elegans] ref|NP_501674.1| C33A12.12 [Caenorhabditis elegans] emb|CAB16465.1| C33A12.12 [Caenorhabditis elegans] 0.0
blast CAB02846 Hypothetical protein C48D1.1 [Caenorhabditis elegans] ref|NP_502537.2| C48D1.1 [Caenorhabditis elegans] 2.0E-66
blast AAB71019 Hypothetical protein F53G2.1 [Caenorhabditis elegans] ref|NP_494284.1| F53G2.1 [Caenorhabditis elegans] 4.0E-62
Protein Domains
Database ID Description E-Value
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.44
Sequence
Target Sequence 
>C. ELEGANS:193389_AT
aaattcgatgtcagccgttcaatgcatgtaatttccctgctcacattgatcctaagccgt
gaaaatggtggaaatggtccaattcactgtcgcttatggagttgttcaagtcttctaaca
gttgactgttttacagactttttaaccggatattacaagattcattacacaaaatataga
gaattaagtgacccaactagtgttccagtattcccaactttatgctctctttccgtttca
ttacatttcccatatgtatgtttcagtgattcacagattcataatgttcaagtgacatac
ccaagagcttttgaatttaattgtaattcatttatgttgttttcagttacatttgcttct
tatctatt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAATTCGATGTCAGCCGTTCAATGC 611 115 1750 Antisense
CAATGCATGTAATTTCCCTGCTCAC 306 183 1769 Antisense
CCTGCTCACATTGATCCTAAGCCGT 113 267 1785 Antisense
GAAATGGTCCAATTCACTGTCGCTT 627 361 1820 Antisense
TTCACTGTCGCTTATGGAGTTGTTC 494 685 1832 Antisense
GGAGTTGTTCAAGTCTTCTAACAGT 418 517 1847 Antisense
GACCCAACTAGTGTTCCAGTATTCC 475 379 1939 Antisense
CCAGTATTCCCAACTTTATGCTCTC 189 273 1954 Antisense
TTTCCGTTTCATTACATTTCCCATA 2 671 1979 Antisense
GTGACATACCCAAGAGCTTTTGAAT 326 483 2041 Antisense
CAGTTACATTTGCTTCTTATCTATT 289 207 2093 Antisense
Sequence Source Affymetrix Proprietary Database