[Home] | [Total List]

[193381_s_at]

Description C09B8.7 /REP_DB=WormBase Gene ID /WP=CE27670 /GEN=pak-1 /TR=Q17850 /GB=AAA68805.2 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Serine-threonine protein kinase
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 16      4grp_high_8_8 > 58      6grp_highest_nonorm > 60      6grp_total > 07      4grp_total > 61      6grp_highest_sub > De      6grp_cgc > 11      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 288
1 2 3 4 range
A 454.2
(3)
P 		410.8
(2.1)
P 		403.1
(1.9)
P 		168.9
(-3)
A 		285
B 437.3
(3)
P 		373.9
(0.4)
P 		415.4
(2.1)
P 		290.1
(-3)
P 		147
C 388.1
(1.5)
P 		352.5
(0.7)
P 		456.6
(3)
P 		189.1
(-3)
A 		268
avr 426.5
(3) 		379.1
(1.6) 		425
(3) 		216
(-3) 		211

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 331
1 2 3 4 5 6 range
A 376.9
(0.2)
P 		474.6
(3)
P 		277.3
(-2.6)
P 		351.7
(-0.5)
P 		264.8
(-3)
P 		328.2
(-1.2)
P 		210
B 399.9
(2.5)
P 		320.3
(-1.4)
P 		409.7
(3)
P 		337.9
(-0.5)
P 		287.7
(-3)
P 		353.7
(0.2)
P 		122
C 595.3
(3)
P 		338
(-2.1)
P 		342.4
(-2)
P 		303.1
(-2.8)
P 		340.8
(-2)
P 		290.5
(-3)
P 		305
avr 457.4
(3) 		377.6
(0) 		343.1
(-1.3) 		330.9
(-1.8) 		297.8
(-3) 		324.1
(-2) 		160
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 141
1 2 3 4 range
A 165.4
(3)
P 		89.2
(-0.2)
P 		105.4
(0.4)
P 		24.7
(-3)
A 		141
B 139.5
(3)
P 		92.4
(-0.6)
P 		96.3
(-0.3)
P 		61.8
(-3)
P 		78
C 128.5
(1.6)
P 		101.3
(0.3)
P 		159.1
(3)
P 		31.9
(-3)
A 		127
avr 144.5
(3) 		94.3
(0.1) 		120.3
(1.6) 		39.5
(-3) 		105

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 160
1 2 3 4 5 6 range
A 69.5
(-2.5)
P 		168.8
(3)
P 		60.4
(-3)
P 		89.2
(-1.4)
P 		79.9
(-1.9)
P 		79.9
(-1.9)
P 		108
B 139.1
(3)
P 		106.6
(-0.9)
P 		99.5
(-1.8)
P 		89.5
(-3)
P 		116.9
(0.3)
P 		131.9
(2.1)
P 		50
C 220.6
(3)
P 		103.1
(-1.4)
P 		87.1
(-2)
P 		61
(-3)
P 		110.3
(-1.1)
P 		97.3
(-1.6)
P 		160
avr 143.1
(3) 		126.2
(1.4) 		82.3
(-2.8) 		79.9
(-3) 		102.4
(-0.9) 		103
(-0.8) 		63
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193381_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17265
Sequence Type Exemplar sequence
Representative Public ID C09B8.7 NCBI
Target Description C09B8.7 /REP_DB=WormBase Gene ID /WP=CE27670 /GEN=pak-1 /TR=Q17850 /GB=AAA68805.2 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Serine-threonine protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029209(11), NM_001029207(11), NM_001029208(11), NM_001029206(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001029209 NCBI Caenorhabditis elegans P21-Activated Kinase family member (pak-1) (pak-1) mRNA, complete cds. 11/11 None
NM_001029207 NCBI Caenorhabditis elegans P21-Activated Kinase family member (pak-1) (pak-1) mRNA, complete cds. 11/11 None
NM_001029208 NCBI Caenorhabditis elegans P21-Activated Kinase family member (pak-1) (pak-1) mRNA, complete cds. 11/11 None
NM_001029206 NCBI Caenorhabditis elegans P21-Activated Kinase family member (pak-1) (pak-1) mRNA, complete cds. 11/11 None
C09B8.7e.3 ENSEMBL cdna:known chromosome:CEL140:X:6044266:6048568:-1 gene:C09B8.7 11/11 A 
C09B8.7e.2 ENSEMBL cdna:known chromosome:CEL140:X:6044267:6048568:-1 gene:C09B8.7 11/11 A 
C09B8.7e.1 ENSEMBL cdna:known chromosome:CEL140:X:6044275:6046119:-1 gene:C09B8.7 9/11 A 
C09B8.7a.2 ENSEMBL cdna:known chromosome:CEL140:X:6044852:6048566:-1 gene:C09B8.7 11/11 None
C09B8.7c.1 ENSEMBL cdna:known chromosome:CEL140:X:6044852:6048316:-1 gene:C09B8.7 11/11 None
C09B8.7b ENSEMBL cdna:known chromosome:CEL140:X:6044852:6048556:-1 gene:C09B8.7 11/11 None
C09B8.7c.2 ENSEMBL cdna:known chromosome:CEL140:X:6044852:6048561:-1 gene:C09B8.7 11/11 None
C09B8.7a.1 ENSEMBL cdna:known chromosome:CEL140:X:6044852:6048568:-1 gene:C09B8.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6044851-6048556(-) 100.0 100.0
Public Domain and Genome References
Ensembl C09B8.7
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAL65775 P21-activated kinase family protein 1, isoform b [Caenorhabditis elegans] ref|NP_001024378.1| P21-Activated Kinase family member (pak-1) [Caenorhabditis elegans] dbj|BAA11844.1| protein kinase [Caenorhabditis elegans] 0.0
blast AAA68805 P21-activated kinase family protein 1, isoform a [Caenorhabditis elegans] ref|NP_001024377.1| P21-Activated Kinase family member (pak-1) [Caenorhabditis elegans] sp|Q17850|PAK1_CAEEL Serine/threonine-protein kinase pak-1 (p21-activated kinase 1) (PAK1) (CePAK) 0.0
blast AAC47308 p21-activated kinase CePAK [Caenorhabditis elegans] 0.0
blast AAO61438 P21-activated kinase family protein 1, isoform c [Caenorhabditis elegans] ref|NP_001024379.1| P21-Activated Kinase family member (pak-1) [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-62
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-62
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-63
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 8.0E-71
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 7.0E-71
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 5.0E-71
hanks 1.1.1 AGC group; AGC I Cyclic nucleotide regulated protein kinase (PKA & PKG); cAPKa 4.0E-22
Protein Domains
Database ID Description E-Value
scop a.1.1.Globins All alpha proteins; Globin-like; Globin-like; Globins 8.0
scop a.1.1.Globins All alpha proteins; Globin-like; Globin-like; Globins 7.59999990463257
Pfam IPR000719 EMBL-EBI Protein kinase 3.8E-31
Pfam IPR000719 EMBL-EBI Protein kinase 5.0E-93
Pfam IPR000095 EMBL-EBI PAK-box/P21-Rho-binding 1.2E-29
Pfam IPR000719 EMBL-EBI Protein kinase 5.0E-93
Pfam IPR000095 EMBL-EBI PAK-box/P21-Rho-binding 1.2E-29
Pfam IPR000719 EMBL-EBI Protein kinase 5.0E-93
Sequence
Target Sequence 
>C. ELEGANS:193381_S_AT
ggagtatcttgccggtggatcattgactgatgttgtcacggagtgccagatggaggatgg
aattattgcagctgtttgcagagaagttcttcaagcgcttgaattcctccacagccgcca
cgtcattcacagagatattaaatctgacaatattcttttgggaatggatggttcggtgaa
attgaccgactttggattctgtgctcagctctcgccggagcaaagaaaacgcacgacaat
ggtcggaactccatactggatggcgccggaagtggtgacccgcaaacaatacggacccaa
ggttgatgtgtggtccttgggaatcatggcgattgagatggtcgaaggagaaccgccata
tttgaatgaaaatccactcagggctatctatctcattgctacaaatggcaaacccgactt
ccctggaagagattccatgactttgttgttcaaggactttgtcgactctgcgttggaagt
acaagttgaaaatcgatggtcggcaagccaactccttacgcatccattcctccgatgcgc
caaaccgcttgcttcactgtactacttaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAGTATCTTGCCGGTGGATCATTG 340 517 1110 Antisense
GACTGATGTTGTCACGGAGTGCCAG 650 373 1134 Antisense
GACTTTGGATTCTGTGCTCAGCTCT 110 373 1297 Antisense
GTGACCCGCAAACAATACGGACCCA 200 481 1384 Antisense
GTGTGGTCCTTGGGAATCATGGCGA 155 489 1417 Antisense
AATCCACTCAGGGCTATCTATCTCA 163 167 1480 Antisense
GCTACAAATGGCAAACCCGACTTCC 4 303 1507 Antisense
GAGATTCCATGACTTTGTTGTTCAA 614 397 1538 Antisense
CAAGGACTTTGTCGACTCTGCGTTG 426 183 1560 Antisense
ATCGATGGTCGGCAAGCCAACTCCT 431 33 1601 Antisense
CGCTTGCTTCACTGTACTACTTAAT 389 255 1655 Antisense
Sequence Source Affymetrix Proprietary Database