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[193376_at] Leucine Rich Repeat (2 copies) (2 domains)

Description Y76A2B.2 /REP_DB=WormBase Gene ID /WP=CE19274 /TR=Q9XWD2 /GB=CAA21743.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies) (2 domains)
Cluster 6grp_total > 58      4grp_total > 47      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 60
1 2 3 4 range
A 51.7
(3)
A 		22.1
(-1.4)
A 		26.4
(-0.8)
A 		11.3
(-3)
A 		40
B 4.6
(-2.4)
A 		3.9
(-3)
A 		6
(-1.2)
A 		10.8
(3)
A 		7
C 63.9
(3)
A 		11.4
(-2.5)
A 		6.4
(-3)
A 		13.7
(-2.2)
A 		58
avr 40.1
(3) 		12.5
(-2.9) 		12.9
(-2.8) 		11.9
(-3) 		28

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 13.4
(3)
A 		4.7
(-2.6)
A 		4.1
(-3)
A 		11.2
(1.6)
A 		9.3
(0.4)
A 		4.5
(-2.7)
A 		9
B 42.3
(3)
A 		16.8
(-0.9)
A 		10.4
(-1.9)
A 		3.4
(-3)
A 		8.8
(-2.2)
A 		21.8
(-0.2)
A 		39
C 6.6
(-2.9)
A 		10.6
(-2.4)
A 		11.1
(-2.4)
A 		6.2
(-3)
A 		7.4
(-2.8)
A 		52.8
(3)
A 		47
avr 20.8
(1.3) 		10.7
(-1.8) 		8.5
(-2.5) 		6.9
(-3) 		8.5
(-2.5) 		26.4
(3) 		20
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 20
1 2 3 4 range
A 18.8
(3)
A 		4.8
(-1.9)
A 		6.9
(-1.2)
A 		1.6
(-3)
A 		17
B 1.5
(-0.7)
A 		1
(-3)
A 		1.4
(-1.2)
A 		2.3
(3)
A 		1
C 21.2
(3)
A 		3.3
(-2.7)
A 		2.2
(-3)
A 		2.3
(-3)
A 		19
avr 13.8
(3) 		3
(-2.5) 		3.5
(-2.3) 		2.1
(-3) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 17
1 2 3 4 5 6 range
A 2.5
(2.1)
A 		1.7
(-0.5)
A 		0.9
(-3)
A 		2.8
(3)
A 		2.8
(3)
A 		1.1
(-2.4)
A 		2
B 14.7
(3)
A 		5.6
(-1)
A 		2.5
(-2.3)
A 		0.9
(-3)
A 		3.6
(-1.8)
A 		8.1
(0.1)
A 		14
C 2.5
(-2.5)
A 		3.2
(-2.3)
A 		2.8
(-2.4)
A 		1.2
(-3)
A 		2.4
(-2.6)
A 		17.7
(3)
A 		17
avr 6.6
(1.1) 		3.5
(-1.5) 		2.1
(-2.6) 		1.6
(-3) 		2.9
(-1.9) 		9
(3) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193376_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6368
Sequence Type Exemplar sequence
Representative Public ID Y76A2B.2 NCBI
Target Description Y76A2B.2 /REP_DB=WormBase Gene ID /WP=CE19274 /TR=Q9XWD2 /GB=CAA21743.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies) (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067397(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067397 NCBI Caenorhabditis elegans Y76A2B.2 (Y76A2B.2) mRNA, complete cds. 10/11 None
GENEFINDER00000001237 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:13536576:13538603:1 11/11 None
Y76A2B.2 ENSEMBL cdna:known chromosome:CEL140:III:13526954:13539468:1 gene:Y76A2B.2 10/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000001229 3/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:13536571-13538599(+) 100.0 100.0
Public Domain and Genome References
Gene Title Leucine Rich Repeat (2 copies) (2 domains)
Ensembl Y76A2B.2
Entrez Gene 190728 Entrez gene
SwissProt Q9XWD2 EMBL-EBI
WormBase CE32279 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA21743 Hypothetical protein Y76A2B.2 [Caenorhabditis elegans] ref|NP_499798.2| Y76A2B.2 [Caenorhabditis elegans] 0.0
blast CAE69259 Hypothetical protein CBG15310 [Caenorhabditis briggsae] 0.0
blast CAA21743 Hypothetical protein Y76A2B.2 [Caenorhabditis elegans] ref|NP_499798.2| Y76A2B.2 [Caenorhabditis elegans] 1.0E-179
blast CAE69259 Hypothetical protein CBG15310 [Caenorhabditis briggsae] 1.0E-126
Protein Domains
Database ID Description E-Value
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.86
Sequence
Target Sequence 
>C. ELEGANS:193376_AT
aagcttgggtgtaatgtgctcgaagtcaccagttcagtcattcaaaggattggtccagtg
tcaagggacatagacaccccagtattccgcccagaacccttcatcatctcctcactgaat
tcggtaattttctcgaattgctccattggatccgtggattcttttgcatttaccaattac
acattatcgattttatcatttaatcattcaagaatcggcgagatgaaaacaagaactata
gagaaatctaaaatttcaaactttgaatttggaggttccacggttaagctttgcaattcc
tcgtctatcgataaatcgaaaattcaaaatttcgaagtttccggagcggaaattgatcga
attaatagtgattggattcaaaattccatgattagaaaattgaaaatcagaagttcaaaa
attggaaaaagcgaaaaaaatattttcaaagactccgtatttgaggaggtggaaatcgat
gatctccacccttcgaataacaggaaacgacataaccacatcaagaccttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGCTTGGGTGTAATGTGCTCGAAG 700 149 523 Antisense
GTGCTCGAAGTCACCAGTTCAGTCA 303 479 538 Antisense
AAGGGACATAGACACCCCAGTATTC 540 103 585 Antisense
CATCATCTCCTCACTGAATTCGGTA 411 213 624 Antisense
TTTTCTCGAATTGCTCCATTGGATC 360 675 650 Antisense
GGATCCGTGGATTCTTTTGCATTTA 97 513 670 Antisense
GCATTTACCAATTACACATTATCGA 132 309 688 Antisense
GGTTCCACGGTTAAGCTTTGCAATT 440 505 796 Antisense
CTTTGCAATTCCTCGTCTATCGATA 504 223 811 Antisense
TGGAAATCGATGATCTCCACCCTTC 30 549 992 Antisense
ACGACATAACCACATCAAGACCTTC 642 91 1029 Antisense
Sequence Source Affymetrix Proprietary Database