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[193365_at] calcium/calmodulin dependent protein kinase

Description F32D8.1 /REP_DB=WormBase Gene ID /WP=CE05780 /TR=Q19962 /GB=CAA98453.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=calcium-calmodulin dependent protein kinase
Cluster 6grp_highest_10_10 > 19      6grp_high1_10_10 > 81      4grp_highest_8_8 > 04      4grp_high_8_8 > 37      6grp_highest_nonorm > 90      6grp_total > 82      4grp_total > 34      6grp_highest_sub > 05      6grp_high1_sub > 04      6grp_rule_based > S5      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 115
1 2 3 4 range
A 137.6
(-2.7)
P 		183.4
(2.1)
P 		134.4
(-3)
P 		192.5
(3)
P 		58
B 100.3
(-3)
P 		215
(3)
P 		154.4
(-0.2)
P 		124.5
(-1.7)
P 		115
C 113
(-3)
P 		175.6
(3)
P 		114.7
(-2.8)
P 		130.4
(-1.3)
P 		63
avr 117
(-3) 		191.3
(3) 		134.5
(-1.6) 		149.1
(-0.4) 		74

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 155
1 2 3 4 5 6 range
A 105.7
(-3)
P 		111.5
(-2.7)
P 		142.6
(-0.9)
P 		167.9
(0.5)
P 		213.2
(3)
P 		106.1
(-3)
P 		108
B 79.7
(-3)
P 		150
(-0.3)
P 		125.5
(-1.2)
P 		234.7
(3)
P 		182.7
(1)
P 		90.1
(-2.6)
P 		155
C 109.3
(-1)
P 		150.9
(1.7)
P 		138.5
(0.9)
P 		162
(2.4)
P 		170.6
(3)
P 		79.3
(-3)
P 		91
avr 98.2
(-2.6) 		137.5
(-0.2) 		135.5
(-0.3) 		188.2
(3) 		188.8
(3) 		91.8
(-3) 		97
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 31
1 2 3 4 range
A 50.1
(3)
P 		39.8
(0.2)
P 		35.1
(-1.1)
P 		28.2
(-3)
P 		22
B 32
(-1.8)
P 		53.1
(3)
P 		35.8
(-0.9)
P 		26.5
(-3)
P 		27
C 37.4
(0.2)
P 		50.5
(3)
P 		40
(0.8)
P 		22
(-3)
P 		29
avr 39.8
(0.8) 		47.8
(3) 		37
(0.1) 		25.6
(-3) 		22

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 55
1 2 3 4 5 6 range
A 19.5
(-3)
P 		39.6
(-0.3)
P 		31.1
(-1.4)
P 		42.6
(0.1)
P 		64.3
(3)
P 		25.8
(-2.2)
P 		45
B 27.7
(-3)
P 		49.9
(-0.1)
P 		30.5
(-2.6)
P 		62.2
(1.5)
P 		74.2
(3)
P 		33.6
(-2.2)
P 		47
C 40.5
(-0.1)
P 		46.1
(1.1)
P 		35.3
(-1.2)
P 		32.6
(-1.7)
P 		55.2
(3)
P 		26.6
(-3)
P 		29
avr 29.2
(-2.9) 		45.2
(-0.2) 		32.3
(-2.4) 		45.8
(-0.1) 		64.6
(3) 		28.7
(-3) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193365_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14212
Sequence Type Exemplar sequence
Representative Public ID F32D8.1 NCBI
Target Description F32D8.1 /REP_DB=WormBase Gene ID /WP=CE05780 /TR=Q19962 /GB=CAA98453.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=calcium-calmodulin dependent protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073369(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073369 NCBI Caenorhabditis elegans F32D8.1 (F32D8.1) mRNA, complete cds. 11/11 None
SNAP00000041023 ENSEMBL cdna:SNAP chromosome:CEL140:V:10884801:10885898:1 11/11 None
GENEFINDER00000041047 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10883464:10885898:1 11/11 None
F32D8.1 ENSEMBL cdna:known chromosome:CEL140:V:10884517:10885898:1 gene:F32D8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10884516-10885898(+) 100.0 100.0
Public Domain and Genome References
Gene Title calcium/calmodulin dependent protein kinase
Ensembl F32D8.1
Entrez Gene 185203 Entrez gene
SwissProt Q19962 EMBL-EBI
WormBase CE37369 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98453 Hypothetical protein F32D8.1 [Caenorhabditis elegans] ref|NP_505770.2| F32D8.1 [Caenorhabditis elegans] 1.0E-178
blast CAE64905 Hypothetical protein CBG09724 [Caenorhabditis briggsae] 1.0E-177
blast CAA98453 Hypothetical protein F32D8.1 [Caenorhabditis elegans] ref|NP_505770.2| F32D8.1 [Caenorhabditis elegans] 1.0E-154
blast CAE64905 Hypothetical protein CBG09724 [Caenorhabditis briggsae] 1.0E-147
blast CAE64905 Hypothetical protein CBG09724 [Caenorhabditis briggsae] 1.0E-146
blast XP_783298 PREDICTED: similar to doublecortin and CaM kinase-like 3 [Strongylocentrotus purpuratus] 3.0E-54
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-59
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-59
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-60
hanks 2.1.6 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; CamKI 4.0E-72
hanks 2.1.6 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; CamKI 9.0E-73
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.1E-91
Pfam IPR000719 EMBL-EBI Protein kinase 1.1E-91
Pfam IPR000719 EMBL-EBI Protein kinase 1.1E-91
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_505770.2 1 233-250
F32D8.1 1 233-250
Sequence
Target Sequence 
>C. ELEGANS:193365_AT
cagatgctgctatcataactctccaagttgcatctgcactcaattatcttcacgaaagaa
atgtggttcacagagatgtcaaacctgaaaatcttcttctcgttgacaaatttagtgtga
agctttgcgattttggattggcatgtcacattcttggacctctgtaccgtatctgtggaa
ccccaacctattgcgcaccagaagttcttcgggagaccggatattcgacaagatgtgata
tttggtcccttggagttgttctttatgttatgcttgttggatatgctccattccgtgcac
cagatcaaaccagattattcaaacttataatgcaagctaaaccaaatctggatatgccag
aatggaaaggaatttcattgaaggctaaagatttggtatctcgcttgatgaataaaactg
aagaacgccgaccacttgcatcccaaataatggctcatccatggattgctcca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAGATGCTGCTATCATAACTCTCCA 37 207 521 Antisense
TAACTCTCCAAGTTGCATCTGCACT 480 637 536 Antisense
GCATCTGCACTCAATTATCTTCACG 525 309 550 Antisense
AAAATCTTCTTCTCGTTGACAAATT 654 131 608 Antisense
TGGCATGTCACATTCTTGGACCTCT 633 541 659 Antisense
TCTGTACCGTATCTGTGGAACCCCA 476 603 681 Antisense
ACCTATTGCGCACCAGAAGTTCTTC 547 87 706 Antisense
GTCCCTTGGAGTTGTTCTTTATGTT 115 475 765 Antisense
TTCCGTGCACCAGATCAAACCAGAT 141 699 811 Antisense
GACCACTTGCATCCCAAATAATGGC 546 383 950 Antisense
AATGGCTCATCCATGGATTGCTCCA 161 163 969 Antisense
Sequence Source Affymetrix Proprietary Database