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[193362_at]

Description C01G6.8 /REP_DB=WormBase Gene ID /WP=CE24774 /GEN=kin-8 /TR=Q17576 /GB=CAB61003.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=protein tyrosine kinase receptor
Cluster 6grp_highest_10_10 > 62      6grp_high1_10_10 > 26      4grp_highest_8_8 > 58      4grp_high_8_8 > 33      6grp_highest_nonorm > 50      6grp_total > 27      4grp_total > 46      6grp_highest_sub > Cu      6grp_cgc > 14      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 400
1 2 3 4 range
A 710.5
(3)
P 		485.3
(-1.9)
P 		433
(-3)
P 		523.2
(-1)
P 		278
B 777.4
(3)
P 		489.3
(-1.3)
P 		460.8
(-1.7)
P 		377.4
(-3)
P 		400
C 729.5
(3)
P 		499.3
(-1.2)
P 		399.1
(-3)
P 		454.8
(-2)
P 		330
avr 739.1
(3) 		491.3
(-1.8) 		431
(-3) 		451.8
(-2.6) 		308

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 701
1 2 3 4 5 6 range
A 571.4
(0.4)
P 		832.8
(3)
P 		231.4
(-3)
P 		483.1
(-0.5)
P 		265.5
(-2.7)
P 		566.4
(0.3)
P 		601
B 455.6
(3)
P 		448
(2.8)
P 		225.4
(-3)
P 		311.3
(-0.8)
P 		324.2
(-0.4)
P 		348.3
(0.2)
P 		230
C 926.7
(3)
P 		467.6
(-1.2)
P 		629.9
(0.3)
P 		277.1
(-3)
P 		459.2
(-1.3)
P 		373
(-2.1)
P 		650
avr 651.2
(3) 		582.8
(1.6) 		362.2
(-2.7) 		357.2
(-2.8) 		349.6
(-3) 		429.2
(-1.4) 		302
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 182
1 2 3 4 range
A 258.7
(3)
P 		105.3
(-2.1)
P 		113.2
(-1.8)
P 		76.6
(-3)
P 		182
B 247.9
(3)
P 		120.8
(-1.6)
P 		106.8
(-2.1)
P 		80.4
(-3)
P 		168
C 241.5
(3)
P 		143.6
(-0.6)
P 		139.1
(-0.7)
P 		76.7
(-3)
P 		165
avr 249.4
(3) 		123.2
(-1.4) 		119.7
(-1.5) 		77.9
(-3) 		172

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 293
1 2 3 4 5 6 range
A 105.3
(-1.7)
P 		296.2
(3)
P 		50.4
(-3)
P 		122.5
(-1.2)
P 		80.1
(-2.3)
P 		137.9
(-0.9)
P 		246
B 158.5
(3)
P 		149.1
(2.5)
P 		54.7
(-3)
P 		82.4
(-1.4)
P 		131.7
(1.5)
P 		129.9
(1.3)
P 		104
C 343.5
(3)
P 		142.7
(-1.2)
P 		160.3
(-0.8)
P 		55.7
(-3)
P 		148.6
(-1.1)
P 		124.9
(-1.6)
P 		288
avr 202.4
(3) 		196
(2.7) 		88.5
(-2.9) 		86.9
(-3) 		120.1
(-1.3) 		130.9
(-0.7) 		116
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193362_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3233
Sequence Type Exemplar sequence
Representative Public ID C01G6.8 NCBI
Target Description C01G6.8 /REP_DB=WormBase Gene ID /WP=CE24774 /GEN=kin-8 /TR=Q17576 /GB=CAB61003.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=protein tyrosine kinase receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026736(11), NM_001026737(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026736 NCBI Caenorhabditis elegans CAN cell Migration defective family member (cam-1) (cam-1) mRNA, complete cds. 11/11 None
NM_001026737 NCBI Caenorhabditis elegans CAN cell Migration defective family member (cam-1) (cam-1) mRNA, complete cds. 11/11 None
SNAP00000013223 ENSEMBL cdna:SNAP chromosome:CEL140:II:9296320:9298887:-1 11/11 None
GENEFINDER00000013243 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:9296320:9299230:-1 11/11 None
C01G6.8a ENSEMBL cdna:known chromosome:CEL140:II:9295831:9310215:-1 gene:C01G6.8 11/11 A 
C01G6.8b ENSEMBL cdna:known chromosome:CEL140:II:9296320:9304733:-1 gene:C01G6.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9296316-9304730(-) 100.0 100.0
Public Domain and Genome References
Ensembl C01G6.8
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAD36478 Hypothetical protein C01G6.8a [Caenorhabditis elegans] emb|CAD36487.1| Hypothetical protein C01G6.8a [Caenorhabditis elegans] emb|CAC29084.1| receptor tyrosine kinase [Caenorhabditis elegans] ref|NP_001021907.1| CAN cell Migration defective family member (cam-1) [Caenorhabditis elegans] 0.0
blast CAA84639 Hypothetical protein C01G6.8b [Caenorhabditis elegans] emb|CAB61003.1| Hypothetical protein C01G6.8b [Caenorhabditis elegans] emb|CAC29085.1| receptor tyrosine kinase [Caenorhabditis elegans] ref|NP_001021908.1| CAN cell Migration defective family member (cam-1) [Caenorhabditis elegans] 0.0
blast CAE72905 Hypothetical protein CBG20223 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
hanks 1.6.3 AGC group; AGC VI phosphorylate ribosomal protein S6; RSK2N 6.0E-60
hanks 1.6.3 AGC group; AGC VI phosphorylate ribosomal protein S6; RSK2N 4.0E-60
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.7E-65
Pfam IPR000001 EMBL-EBI Kringle 6.1E-18
Pfam IPR000719 EMBL-EBI Protein kinase 4.7E-65
Pfam IPR000001 EMBL-EBI Kringle 6.1E-18
Pfam IPR000719 EMBL-EBI Protein kinase 4.7E-65
Pfam IPR000001 EMBL-EBI Kringle 6.1E-18
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 3.8E-9
Pfam IPR000719 EMBL-EBI Protein kinase 4.7E-65
Pfam IPR000001 EMBL-EBI Kringle 6.1E-18
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 3.8E-9
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001021907.1 1 467-489
NP_001021908.1 1 441-463
C01G6.8a 1 467-489
C01G6.8b 1 441-463
SNAP00000013223 1 309-331
GENEFINDER00000013243 1 341-363
Sequence
Target Sequence 
>C. ELEGANS:193362_AT
taagatgctccatcgctcttggatgccagtccgttggatgtcaaaagaagcaattgaaca
aggaagattcagtgaagcatctgatgtatggtcatttggagtcacactttgggaaatttg
gtctttcggtcgtcaaccatacgaaggagcatcgaatcaacaagttattgagcttgttgc
aaaccgacatttactagaatgccctcacaattgtccaaccaacatctacagtttgatggt
tgaatgttggcatgaaaacattgagcgaagaccaacattctcggaaattcgtagtcgatt
gcagtcatggtcattggcaagtccagctcattcgattcttcagcagcataataatagagc
aggatctcatagtggatcatctggagccggtcgaccaccaacccatcaacgtggatatcc
gagccaaaagcttcatcgacgtgtcgaaggagcatccccgctgatgaaacgtcatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TAAGATGCTCCATCGCTCTTGGATG 212 637 2205 Antisense
CTTGGATGCCAGTCCGTTGGATGTC 101 219 2222 Antisense
TTGGTCTTTCGGTCGTCAACCATAC 389 701 2322 Antisense
TAGAATGCCCTCACAATTGTCCAAC 347 651 2399 Antisense
GTAGTCGATTGCAGTCATGGTCATT 4 457 2495 Antisense
GTCATTGGCAAGTCCAGCTCATTCG 8 469 2514 Antisense
CTCATTCGATTCTTCAGCAGCATAA 229 229 2531 Antisense
CATAGTGGATCATCTGGAGCCGGTC 85 215 2572 Antisense
GACCACCAACCCATCAACGTGGATA 260 383 2597 Antisense
GAGCCAAAAGCTTCATCGACGTGTC 460 383 2625 Antisense
GCATCCCCGCTGATGAAACGTCATG 463 309 2656 Antisense
Sequence Source Affymetrix Proprietary Database