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[193361_at] 7 transmembrane receptor (Secretin family)

Description C18B12.2 /REP_DB=WormBase Gene ID /WP=CE23557 /TR=Q9U3P6 /GB=CAA20927.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=7 transmembrane receptor (Secretin family)
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 05      4grp_high_8_8 > 19      6grp_highest_nonorm > 80      6grp_total > 05      4grp_total > 21      6grp_highest_sub > De      6grp_high1_sub > De      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 200
1 2 3 4 range
A 225.9
(1.6)
P 		193.1
(0.6)
P 		72.9
(-3)
A 		273
(3)
P 		200
B 181.8
(1.2)
P 		170.1
(0.4)
P 		119.2
(-3)
P 		208.4
(3)
P 		89
C 190.8
(1.5)
P 		95
(-3)
A 		154.3
(-0.2)
P 		224.1
(3)
P 		129
avr 199.5
(1.2) 		152.7
(-1.1) 		115.5
(-3) 		235.2
(3) 		120

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 202
1 2 3 4 5 6 range
A 273.3
(3)
P 		160.4
(-1)
P 		162.9
(-0.9)
P 		121.3
(-2.4)
P 		136.4
(-1.9)
P 		105
(-3)
P 		168
B 290.6
(3)
P 		250.7
(1.6)
P 		121.4
(-3)
P 		183.3
(-0.8)
P 		202.1
(-0.1)
P 		143.7
(-2.2)
P 		169
C 225.8
(2.5)
P 		237
(3)
P 		165.2
(0.1)
P 		169.7
(0.3)
P 		149.8
(-0.5)
P 		88.7
(-3)
P 		148
avr 263.2
(3) 		216
(1.1) 		149.8
(-1.5) 		158.1
(-1.2) 		162.8
(-1) 		112.5
(-3) 		151
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 63
1 2 3 4 range
A 82.2
(3)
P 		41.9
(-0.8)
P 		19.1
(-3)
A 		40
(-1)
P 		63
B 58
(3)
P 		42
(-0.2)
P 		27.6
(-3)
P 		44.4
(0.3)
P 		30
C 63.2
(3)
P 		27.3
(-3)
A 		53.8
(1.4)
P 		37.8
(-1.2)
P 		36
avr 67.8
(3) 		37.1
(-2.4) 		33.5
(-3) 		40.7
(-1.7) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 76
1 2 3 4 5 6 range
A 50.4
(1.7)
P 		57.1
(3)
P 		35.5
(-1.1)
P 		30.8
(-2)
P 		41.2
(-0)
P 		25.6
(-3)
P 		32
B 101.1
(3)
P 		83.4
(1.5)
P 		29.5
(-3)
P 		48.6
(-1.4)
P 		82.1
(1.4)
P 		53.6
(-1)
P 		72
C 83.7
(3)
P 		72.3
(1.7)
P 		42
(-1.6)
P 		34.1
(-2.5)
P 		48.5
(-0.9)
P 		29.7
(-3)
P 		54
avr 78.4
(3) 		70.9
(1.9) 		35.7
(-3) 		37.8
(-2.7) 		57.3
(0) 		36.3
(-2.9) 		43
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193361_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17811
Sequence Type Exemplar sequence
Representative Public ID C18B12.2 NCBI
Target Description C18B12.2 /REP_DB=WormBase Gene ID /WP=CE23557 /TR=Q9U3P6 /GB=CAA20927.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=7 transmembrane receptor (Secretin family)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078095(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078095 NCBI Caenorhabditis elegans C18B12.2 (C18B12.2) mRNA, complete cds. 11/11 None
GENEFINDER00000043450 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:15026238:15030711:1 11/11 None
SNAP00000043443 ENSEMBL cdna:SNAP chromosome:CEL140:X:15028231:15030711:1 11/11 None
C18B12.2 ENSEMBL cdna:known chromosome:CEL140:X:15026224:15031000:1 gene:C18B12.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:15026237-15030711(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7 transmembrane receptor (Secretin family)
Ensembl C18B12.2
Entrez Gene 181598 Entrez gene
SwissProt Q9U3P6 EMBL-EBI
WormBase CE23557 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.20991.1.S1_S_AT similar to corticotropin releasing hormone receptor 1 cfa
DROSGENOME1:147095_AT dm
DROSOPHILA_2:1639961_AT dm
DROSOPHILA_2:1631164_A_AT dm
DROSGENOME1:147096_AT dm
CHICKEN:GGA.14391.1.S1_AT corticotropin releasing hormone receptor 1 gga
HG-U133_PLUS_2:211897_S_AT corticotropin releasing hormone receptor 1 hs
HG-U133A:211897_S_AT corticotropin releasing hormone receptor 1 hs
HG-U133A_2:211897_S_AT corticotropin releasing hormone receptor 1 hs
HG-U133_PLUS_2:208593_X_AT corticotropin releasing hormone receptor 1 hs
HG-U133A:208593_X_AT corticotropin releasing hormone receptor 1 hs
HG-U133A_2:208593_X_AT corticotropin releasing hormone receptor 1 hs
HG-U95AV2:40650_R_AT corticotropin releasing hormone receptor 1 hs
HU35KSUBA:X72304_S_AT corticotropin releasing hormone receptor 1 hs
HUGENEFL:X72304_AT corticotropin releasing hormone receptor 1 hs
HUGENEFL:L23333_S_AT corticotropin releasing hormone receptor 1 hs
U133_X3P:G5815472_3P_A_AT corticotropin releasing hormone receptor 1 hs
U133_X3P:HS.79117.3.S2_3P_AT corticotropin releasing hormone receptor 1 hs
HG-U133A_2:214619_AT corticotropin releasing hormone receptor 1 hs
HG-FOCUS:214619_AT corticotropin releasing hormone receptor 1 hs
HG-U133_PLUS_2:214619_AT corticotropin releasing hormone receptor 1 hs
HG-U133A:214619_AT corticotropin releasing hormone receptor 1 hs
HG-U95AV2:40651_S_AT corticotropin releasing hormone receptor 1 hs
MOE430A:1418810_AT corticotropin releasing hormone receptor 1 mm
MOUSE430_2:1418810_AT corticotropin releasing hormone receptor 1 mm
MOUSE430A_2:1418810_AT corticotropin releasing hormone receptor 1 mm
MOUSE430_2:1427782_A_AT corticotropin releasing hormone receptor 1 mm
MOE430A:1427782_A_AT corticotropin releasing hormone receptor 1 mm
MOUSE430A_2:1427782_A_AT corticotropin releasing hormone receptor 1 mm
MU11KSUBB:X72305_S_AT corticotropin releasing hormone receptor 1 mm
MG-U74AV2:95290_AT corticotropin releasing hormone receptor 1 mm
RG-U34A:U53486MRNA_S_AT corticotropin releasing hormone receptor 1 rn
RG-U34A:AF039203UTR#1_AT corticotropin releasing hormone receptor 1 rn
RG-U34A:U53500_S_AT corticotropin releasing hormone receptor 1 rn
RAE230A:1398289_A_AT corticotropin releasing hormone receptor 1 rn
RAT230_2:1398289_A_AT corticotropin releasing hormone receptor 1 rn
RAE230A:1387683_AT corticotropin releasing hormone receptor 1 rn
RAT230_2:1387683_AT corticotropin releasing hormone receptor 1 rn
RG-U34B:RC_AI059206_AT Corticotropin releasing hormone receptor 1 rn
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA20927 Hypothetical protein C18B12.2 [Caenorhabditis elegans] ref|NP_510496.1| C18B12.2 [Caenorhabditis elegans] gb|AAQ84886.1| secretin receptor-like protein SEB-3 [Caenorhabditis elegans] 0.0
blast CAE63268 Hypothetical protein CBG07642 [Caenorhabditis briggsae] 0.0
blast CAE63268 Hypothetical protein CBG07642 [Caenorhabditis briggsae] 1.0E-176
blast BAC77166.1 calctonin receptor like protein [Rana catesbeiana] 2.0E-32
Protein Domains
Database ID Description E-Value
Pfam IPR001879 EMBL-EBI Hormone receptor, extracellular 3.5E-21
Pfam IPR000832 EMBL-EBI G-protein coupled receptor family 2 (secretin-like) 4.6E-44
Pfam IPR000832 EMBL-EBI G-protein coupled receptor family 2 (secretin-like) 4.7E-38
Pfam IPR000832 EMBL-EBI G-protein coupled receptor family 2 (secretin-like) 4.6E-44
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510496.1 7 115-137,158-177,197-219,240-262,277-299,320-342,352-374
C18B12.2 7 115-137,158-177,197-219,240-262,277-299,320-342,352-374
GENEFINDER00000043450 7 118-140,173-195,219-241,254-276,296-318,339-361,371-393
SNAP00000043443 7 38-60,81-100,120-142,163-185,200-222,243-265,275-297
Sequence
Target Sequence 
>C. ELEGANS:193361_AT
gtaacggcatgggcattggttcatcaatacatatccagccaacaaacaaattcattttgt
tggctgccttatgcccagggactccatttgtggattcttgctggaactatgggatccgca
ttaattatgaatcttatattcttgcttatgattgtggtgatattggtgcaaaagttacga
acggagaattctgcggaatccaagaaaatttggagaacaataaaagcaactcttttgtta
gtgccactcctcggcatttcaaacatccctcttttttacgagccggagcacccgagctct
gtctacatgctcggctcggctattttacaacatagtcagggtatttttattgcggtcttg
tattgcttcttgaatagtgaaatccagggagcgctgaagcggc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTAACGGCATGGGCATTGGTTCATC 616 459 763 Antisense
GGTTCATCAATACATATCCAGCCAA 358 507 780 Antisense
ATTTTGTTGGCTGCCTTATGCCCAG 450 13 816 Antisense
ATGCCCAGGGACTCCATTTGTGGAT 625 41 833 Antisense
GCAACTCTTTTGTTAGTGCCACTCC 392 319 988 Antisense
TCCCTCTTTTTTACGAGCCGGAGCA 547 597 1028 Antisense
CACCCGAGCTCTGTCTACATGCTCG 403 201 1051 Antisense
TGCTCGGCTCGGCTATTTTACAACA 227 581 1070 Antisense
GTCAGGGTATTTTTATTGCGGTCTT 693 465 1097 Antisense
TTGCGGTCTTGTATTGCTTCTTGAA 136 701 1112 Antisense
GAAATCCAGGGAGCGCTGAAGCGGC 151 363 1141 Antisense
Sequence Source Affymetrix Proprietary Database