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[193356_s_at] metabotropic glutamate receptor

Description F45H11.4 /REP_DB=WormBase Gene ID /WP=CE17833 /GEN=mgl-2 /TR=Q93564 /GB=CAB01711.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=metabotropic glutamate receptor
Cluster 6grp_total > 23      4grp_total > 23      6grp_cgc > 20      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 199
1 2 3 4 range
A 153.7
(3)
A 		35.6
(-3)
A 		78.2
(-0.8)
A 		140.5
(2.3)
A 		118
B 213.5
(3)
P 		48.7
(-3)
A 		52.2
(-2.9)
A 		207.2
(2.8)
A 		165
C 234.2
(3)
A 		94.6
(-2.7)
A 		86.2
(-3)
A 		217.2
(2.3)
A 		148
avr 200.5
(3) 		59.6
(-3) 		72.2
(-2.5) 		188.3
(2.5) 		141

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 165
1 2 3 4 5 6 range
A 202.1
(3)
A 		96.1
(-2.3)
A 		100.1
(-2.1)
A 		133.2
(-0.5)
A 		82.5
(-3)
A 		96
(-2.3)
A 		120
B 172.7
(2.7)
A 		117.9
(-0.6)
A 		177.8
(3)
A 		149.4
(1.3)
A 		79
(-3)
A 		91.1
(-2.3)
A 		99
C 107.1
(0)
A 		175
(3)
A 		138.8
(1.4)
A 		114.6
(0.4)
A 		37.2
(-3)
A 		76.1
(-1.3)
A 		138
avr 160.6
(3) 		129.7
(1) 		138.9
(1.6) 		132.4
(1.2) 		66.2
(-3) 		87.7
(-1.6) 		94
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 70
1 2 3 4 range
A 56
(3)
A 		7.7
(-3)
A 		20.4
(-1.4)
A 		20.6
(-1.4)
A 		48
B 68.1
(3)
P 		12
(-3)
A 		12.1
(-3)
A 		44.2
(0.4)
A 		56
C 77.5
(3)
A 		27.2
(-3)
A 		30
(-2.7)
A 		36.6
(-1.9)
A 		50
avr 67.2
(3) 		15.6
(-3) 		20.8
(-2.4) 		33.8
(-0.9) 		52

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 48
1 2 3 4 5 6 range
A 37.3
(3)
A 		34.2
(1.8)
A 		21.8
(-3)
A 		33.8
(1.6)
A 		24.9
(-1.8)
A 		23.4
(-2.4)
A 		16
B 60.1
(3)
A 		39.3
(-1.5)
A 		43.2
(-0.6)
A 		39.6
(-1.4)
A 		32.1
(-3)
A 		34
(-2.6)
A 		28
C 39.7
(1)
A 		53.4
(3)
A 		35.3
(0.4)
A 		23
(-1.4)
A 		12
(-3)
A 		25.5
(-1)
A 		41
avr 45.7
(3) 		42.3
(2.1) 		33.4
(-0.3) 		32.1
(-0.6) 		23
(-3) 		27.6
(-1.8) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193356_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1396
Sequence Type Exemplar sequence
Representative Public ID F45H11.4 NCBI
Target Description F45H11.4 /REP_DB=WormBase Gene ID /WP=CE17833 /GEN=mgl-2 /TR=Q93564 /GB=CAB01711.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=metabotropic glutamate receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060319(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060319 NCBI Caenorhabditis elegans Metabotropic GLutamate receptor family member (mgl-2) (mgl-2) mRNA, complete cds. 11/11 A 
F45H11.4 ENSEMBL cdna:known chromosome:CEL140:I:10390889:10399438:-1 gene:F45H11.4 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000042273 8/11 Cross Hyb Matching Probes None
GENEFINDER00000042277 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10391196-10399369(-) 100.0 100.0
Public Domain and Genome References
Gene Title metabotropic glutamate receptor
Gene Symbol mgl-2
Ensembl F45H11.4
Entrez Gene 172914 Entrez gene
SwissProt Q93564 EMBL-EBI
WormBase CE33786 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.1457.1.S1_S_AT similar to glutamate receptor, metabotropic 1 cfa
CANINE_2:CFAAFFX.1460.1.S1_AT similar to glutamate receptor, metabotropic 1 cfa
CANINE_2:CFAAFFX.1460.1.S1_S_AT similar to glutamate receptor, metabotropic 1 cfa
CHICKEN:GGAAFFX.7793.4.S1_S_AT similar to metabotropic glutamate receptor gga
HG-U133_PLUS_2:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-FOCUS:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A_2:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-U133_PLUS_2:210939_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A:210939_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A_2:210939_S_AT glutamate receptor, metabotropic 1 hs
HG-U95AV2:33509_AT glutamate receptor, metabotropic 1 hs
HG-U133_PLUS_2:210940_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A:210940_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A_2:210940_S_AT glutamate receptor, metabotropic 1 hs
HUGENEFL:U31215_S_AT glutamate receptor, metabotropic 1 hs
HUGENEFL:U31216_S_AT glutamate receptor, metabotropic 1 hs
HUGENEFL:L76627_AT glutamate receptor, metabotropic 1 hs
U133_X3P:G945098_3P_A_AT glutamate receptor, metabotropic 1 hs
U133_X3P:G6006005_3P_A_AT glutamate receptor, metabotropic 1 hs
U133_X3P:G1477389_3P_A_AT glutamate receptor, metabotropic 1 hs
HG-U95AV2:31468_F_AT glutamate receptor, metabotropic 1 hs
HG-U95AV2:33510_S_AT glutamate receptor, metabotropic 1 hs
MOUSE430_2:1425700_AT glutamate receptor, metabotropic 1 mm
MOE430A:1425700_AT glutamate receptor, metabotropic 1 mm
MOUSE430A_2:1425700_AT glutamate receptor, metabotropic 1 mm
RN-U34:M61099_AT glutamate receptor, metabotropic 1 rn
RG-U34A:M61099_AT glutamate receptor, metabotropic 1 rn
RAE230A:1371180_A_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1371180_A_AT glutamate receptor, metabotropic 1 rn
RAE230A:1371181_X_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1371181_X_AT glutamate receptor, metabotropic 1 rn
RAE230A:1387286_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1387286_AT glutamate receptor, metabotropic 1 rn
RAE230A:1371238_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1371238_AT glutamate receptor, metabotropic 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
8067 metabotropic glutamate, GABA-B-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01699 Hypothetical protein F45H11.4 [Caenorhabditis elegans] emb|CAB01711.2| Hypothetical protein F45H11.4 [Caenorhabditis elegans] ref|NP_492720.2| Metabotropic GLutamate receptor family member (mgl-2) [Caenorhabditis elegans] 0.0
blast CAE58931 Hypothetical protein CBG02196 [Caenorhabditis briggsae] 0.0
blast CAH68968 novel protein similar to vertabrate glutamate receptor, metabotropic 1 (GRM1) [Danio rerio] 1.0E-178
Protein Domains
Database ID Description E-Value
Pfam IPR000337 EMBL-EBI G-protein coupled receptor family 3, metabotropic glutamate receptor-like 1.9E-57
Pfam IPR000337 EMBL-EBI G-protein coupled receptor family 3, metabotropic glutamate receptor-like 7.0E-17
Pfam IPR004826 EMBL-EBI Maf transcription factor 3.7E-83
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 1.7E-66
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492720.2 6 580-602,615-637,642-661,689-711,792-809,822-844
F45H11.4 6 580-602,615-637,642-661,689-711,792-809,822-844
Sequence
Target Sequence 
>C. ELEGANS:193356_S_AT
ttttgcacgttgctccgaagtcgaggtgttcaacctctcgcgctgtctcaagctacacca
ttatgagtggcaatcaacagttaatgagcccaatgggctctgtgagctcatctgctggct
ctggatctcctagtccaatgtcatcatttgatcatttgtcagatgaagaacttgctcaga
tctccgttcgacagctcaatcagaaacttatgggtcaagatagaaacgtggtgatgcaat
ggaaacaaaaacgaagaactctgaagaatcgaggatatgcgttgaattgccgtgcgagac
gagtcaataatcaggtacaactggaggctgataatatgatgcttcgaaatcagataaaaa
ctcttcgagaagctctcagtgaagcccaaatgagactacattactacgagccagtgttct
atcaggcatatccaagtattgtaccaagtacgacgtctccagtaactgtatctctaccaa
caattgctcgaccaataccagttccacctgattcgac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTTGCACGTTGCTCCGAAGTCGAG 679 671 3254 Antisense
AAGTCGAGGTGTTCAACCTCTCGCG 564 157 3271 Antisense
GCTGTCTCAAGCTACACCATTATGA 258 295 3295 Antisense
AATGGGCTCTGTGAGCTCATCTGCT 536 163 3345 Antisense
GCTCTGGATCTCCTAGTCCAATGTC 511 299 3371 Antisense
AAGAACTTGCTCAGATCTCCGTTCG 709 151 3419 Antisense
TCTCCGTTCGACAGCTCAATCAGAA 266 611 3434 Antisense
TATGCGTTGAATTGCCGTGCGAGAC 623 657 3529 Antisense
TACTACGAGCCAGTGTTCTATCAGG 396 645 3655 Antisense
AAGTACGACGTCTCCAGTAACTGTA 460 137 3699 Antisense
CAATACCAGTTCCACCTGATTCGAC 395 181 3746 Antisense
Sequence Source Affymetrix Proprietary Database