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[193348_s_at] proteasome component (A-type)

Description ZK945.2 /REP_DB=WormBase Gene ID /WP=CE01733 /GEN=pas-7 /TR=SW:Q09583 /GB=CAA88436.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=proteasome component (A-type)
Cluster 6grp_highest_10_10 > 26      6grp_high1_10_10 > 63      4grp_highest_8_8 > 10      4grp_high_8_8 > 55      6grp_highest_nonorm > 52      6grp_total > 60      4grp_total > 56      6grp_highest_sub > 03      6grp_cgc > 93      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1062
1 2 3 4 range
A 642.6
(-3)
P 		1421.3
(2.5)
P 		1492.4
(3)
P 		695.5
(-2.6)
P 		850
B 718.2
(-2.5)
P 		1055.3
(-0.4)
P 		1600.6
(3)
P 		646.3
(-3)
P 		954
C 704.1
(-1.7)
P 		1152.1
(1.7)
P 		1329.6
(3)
P 		539
(-3)
P 		791
avr 688.3
(-2.6) 		1209.6
(1.1) 		1474.2
(3) 		626.9
(-3) 		847

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 404
1 2 3 4 5 6 range
A 658.8
(-0.4)
P 		599.6
(-1.3)
P 		886.8
(3)
P 		855.2
(2.5)
P 		482.8
(-3)
P 		586.5
(-1.5)
P 		404
B 539.8
(-3)
P 		586.6
(-2.1)
P 		851.7
(3)
P 		735.6
(0.8)
P 		542.8
(-2.9)
P 		555
(-2.7)
P 		312
C 629.3
(-0.9)
P 		550.4
(-2.2)
P 		844.4
(2.7)
P 		865.3
(3)
P 		499
(-3)
P 		574.5
(-1.8)
P 		366
avr 609.3
(-1.3) 		578.9
(-1.8) 		861
(3) 		818.7
(2.3) 		508.2
(-3) 		572
(-1.9) 		353
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 373
1 2 3 4 range
A 234
(-0.2)
P 		308.5
(1.3)
P 		390.1
(3)
P 		101.8
(-3)
P 		288
B 229
(-0.7)
P 		260.6
(0.2)
P 		370.9
(3)
P 		137.7
(-3)
P 		233
C 233.1
(-0.7)
P 		331.2
(0.9)
P 		463.4
(3)
P 		90.9
(-3)
P 		373
avr 232
(-0.5) 		300.1
(0.8) 		408.1
(3) 		110.1
(-3) 		298

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 112
1 2 3 4 5 6 range
A 121.4
(-3)
P 		213.3
(2.8)
P 		193.1
(1.5)
P 		216.9
(3)
P 		145.7
(-1.5)
P 		142.8
(-1.7)
P 		96
B 187.8
(-3)
P 		195.3
(-1.6)
P 		206.8
(0.5)
P 		194.8
(-1.7)
P 		220.5
(3)
P 		207
(0.5)
P 		33
C 233.3
(3)
P 		167.9
(-2.5)
P 		214.9
(1.5)
P 		174
(-2)
P 		161.5
(-3)
P 		192.3
(-0.4)
P 		72
avr 180.8
(-2) 		192.2
(0.4) 		204.9
(3) 		195.2
(1) 		175.9
(-3) 		180.7
(-2) 		29
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193348_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3548
Sequence Type Exemplar sequence
Representative Public ID ZK945.2 NCBI
Target Description ZK945.2 /REP_DB=WormBase Gene ID /WP=CE01733 /GEN=pas-7 /TR=SW:Q09583 /GB=CAA88436.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=proteasome component (A-type)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063776(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063776 NCBI Caenorhabditis elegans Proteasome Alpha Subunit family member (pas-7) (pas-7) mRNA, complete cds. 11/11 None
SNAP00000015333 ENSEMBL cdna:SNAP chromosome:CEL140:II:10098918:10099764:-1 11/11 None
GENEFINDER00000015345 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:10098918:10099764:-1 11/11 None
ZK945.2.2 ENSEMBL cdna:known chromosome:CEL140:II:10098721:10099765:-1 gene:ZK945.2 11/11 None
ZK945.2.1 ENSEMBL cdna:known chromosome:CEL140:II:10098721:10099778:-1 gene:ZK945.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10098883-10099761(-) 100.0 100.0
Public Domain and Genome References
Gene Title proteasome component (A-type)
Gene Symbol pas-7
Ensembl ZK945.2
Entrez Gene 174571 Entrez gene
SwissProt Q09583 EMBL-EBI
WormBase CE36420 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1593251_AT similar to proteasome alpha 3 subunit isoform 2 cfa
CANINE:1584430_S_AT similar to proteasome alpha 3 subunit isoform 2 cfa
CANINE_2:CFA.4336.1.S1_S_AT similar to proteasome alpha 3 subunit isoform 2 cfa
CANINE_2:CFA.4336.2.S1_A_AT similar to proteasome alpha 3 subunit isoform 2 cfa
DROSOPHILA_2:1634795_A_AT Proteasome 7 subunit dm
DROSGENOME1:142853_AT Proteasome 7 subunit dm
CHICKEN:GGAAFFX.11855.1.S1_S_AT proteasome (prosome, macropain) subunit, alpha type, 3 gga
HG-U133_PLUS_2:232648_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U133B:232648_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U95AV2:1448_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HC-G110:1448_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HUGENEFL:D00762_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U133A:201532_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U133_PLUS_2:201532_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-FOCUS:201532_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U133A_2:201532_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
U133_X3P:G4506182_3P_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
U133_X3P:HS.270791.0.A1_3P_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U95E:85203_AT proteasome (prosome, macropain) subunit, alpha type, 3 hs
HU35KSUBA:AA348809_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
HU35KSUBC:RC_R77952_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U133_PLUS_2:237300_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U133B:237300_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U95E:81879_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
HG-U95D:88326_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
HU35KSUBC:RC_C20657_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
U133_X3P:HS.125702.0.A1_3P_AT Proteasome (prosome, macropain) subunit, alpha type, 3 hs
MU11KSUBA:AA690872_F_AT proteasome (prosome, macropain) subunit, alpha type 3 mm
MU11KSUBA:C80757_RC_F_AT proteasome (prosome, macropain) subunit, alpha type 3 mm
MG-U74AV2:92544_F_AT proteasome (prosome, macropain) subunit, alpha type 3 mm
MG-U74CV2:166835_AT proteasome (prosome, macropain) subunit, alpha type 3 mm
MOE430A:1448442_A_AT proteasome (prosome, macropain) subunit, alpha type 3 mm
MOUSE430A_2:1448442_A_AT proteasome (prosome, macropain) subunit, alpha type 3 mm
MOUSE430_2:1448442_A_AT proteasome (prosome, macropain) subunit, alpha type 3 mm
MG-U74CV2:135435_AT Proteasome subunit C8 (Psma3) mm
MOE430B:1441707_AT Proteasome subunit C8 (Psma3) mm
MOUSE430_2:1441707_AT Proteasome subunit C8 (Psma3) mm
MU19KSUBA:TC15610_F_AT Proteasome subunit C8 (Psma3) mm
MU19KSUBC:TC38867_F_AT Proteasome subunit C8 (Psma3) mm
RN-U34:D90258_S_AT proteasome (prosome, macropain) subunit, alpha type 3 rn
RG-U34A:D90258_S_AT proteasome (prosome, macropain) subunit, alpha type 3 rn
RG-U34B:RC_AI008546_AT proteasome (prosome, macropain) subunit, alpha type 3 rn
RAE230A:1368507_AT proteasome (prosome, macropain) subunit, alpha type 3 rn
RAT230_2:1368507_AT proteasome (prosome, macropain) subunit, alpha type 3 rn
RAE230A:1368508_AT proteasome (prosome, macropain) subunit, alpha type 3 rn
RAT230_2:1368508_AT proteasome (prosome, macropain) subunit, alpha type 3 rn
RG-U34B:RC_AA849028_AT Proteasome subunit alpha type 3-like rn
RG-U34B:RC_AI059664_AT Proteasome subunit alpha type 3-like rn
YEAST_2:1776223_AT 20S proteasome alpha-type subunit Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6511 ubiquitin-dependent protein catabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5839 proteasome core complex (sensu Eukaryota) inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4175 endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88436 Hypothetical protein ZK945.2 [Caenorhabditis elegans] ref|NP_496177.2| Proteasome Alpha Subunit family member (pas-7) [Caenorhabditis elegans] sp|Q09583|PSA3_CAEEL Proteasome subunit alpha type 3 (Proteasome subunit alpha 7) 1.0E-124
blast CAE67821 Hypothetical protein CBG13401 [Caenorhabditis briggsae] 1.0E-116
Protein Domains
Database ID Description E-Value
Pfam IPR001353 EMBL-EBI Peptidase T1, 20S proteasome 5.4E-51
Sequence
Target Sequence 
>C. ELEGANS:193348_S_AT
gctgatctcttccaaactttacactgataacgctaatccaagaatgtttaacgtgaacga
caatgttggtgtcgcagttgctggaaactatccagatggtttcgctctgaagaactatgc
ttacggagaagcaatgaagtggctcaaagactaccgtgagccaatgccgattcagaatat
tgctaactcagttgctgagtacattcacattcacactctcggcattagtcgtccgtttgg
agcaggagccttcttcatgtcatggaacaaacaaactggaggacgtcttttccttgtgga
gccatcaggtctaaactatgaatacaaggcatgggctgtcggaaaacatcgccaagccgc
aaaagctgagattgagaagctgaagatcgaggagctggatgtgaatcaactcgtgaagga
agctgctcgaatcattatggtggtgcgtgacgagaacaaggataaaaacgttcaaatcga
aatgggatgggtcggtgagcagacgaacggaaagtacgaagaagttccaagcgaggttgt
cactgctgcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTGATCTCTTCCAAACTTTACACT 358 295 168 Antisense
ACAATGTTGGTGTCGCAGTTGCTGG 64 113 227 Antisense
TACCGTGAGCCAATGCCGATTCAGA 15 651 319 Antisense
GAGTACATTCACATTCACACTCTCG 283 399 364 Antisense
CACACTCTCGGCATTAGTCGTCCGT 282 195 379 Antisense
GGAGCCTTCTTCATGTCATGGAACA 250 521 412 Antisense
AACTGGAGGACGTCTTTTCCTTGTG 60 137 441 Antisense
TTTCCTTGTGGAGCCATCAGGTCTA 48 665 456 Antisense
GGCATGGGCTGTCGGAAAACATCGC 22 537 495 Antisense
GAAAACATCGCCAAGCCGCAAAAGC 511 355 509 Antisense
TCCAAGCGAGGTTGTCACTGCTGCC 446 587 693 Antisense
Sequence Source Affymetrix Proprietary Database