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[193339_s_at] tyrosine-protein kinase (FES/FPS subfamily)

Description R05H5.4 /REP_DB=WormBase Gene ID /WP=CE02291 /TR=Q21764 /GB=CAA88727.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (FES-FPS subfamily)
Cluster 6grp_total > 96      4grp_total > 12      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 24
1 2 3 4 range
A 15.3
(0.8)
A
14.2
(0.2)
A
8.6
(-3)
A
19.2
(3)
A
11
B 13.7
(3)
A
11.1
(1.1)
A
5.3
(-3)
A
8.8
(-0.5)
A
8
C 11.6
(-2.3)
A
9.2
(-3)
A
17.5
(-0.5)
A
29
(3)
A
20
avr 13.5
(-0.9)
11.5
(-2.3)
10.5
(-3)
19
(3)
9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 256
1 2 3 4 5 6 range
A 14.1
(-2.9)
A
10.3
(-3)
A
13.4
(-2.9)
A
113.8
(-0.5)
A
152.4
(0.4)
A
262.3
(3)
A
252
B 13.7
(-2.8)
A
8.8
(-3)
A
14.5
(-2.8)
A
138.5
(1.5)
A
179.5
(3)
A
180.7
(3)
A
172
C 6.3
(-3)
A
23.4
(-2.5)
A
28.9
(-2.3)
A
141.8
(1)
A
112.3
(0.1)
A
209.8
(3)
M
204
avr 11.4
(-3)
14.2
(-2.9)
18.9
(-2.8)
131.4
(0.5)
148.1
(1)
217.6
(3)
206
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5
1 2 3 4 range
A 5.6
(3)
A
3.1
(-1.5)
A
2.3
(-3)
A
2.8
(-2.1)
A
3
B 4.4
(3)
A
2.8
(-0)
A
1.2
(-3)
A
1.9
(-1.7)
A
3
C 3.9
(-0.8)
A
2.6
(-3)
A
6.1
(3)
A
4.9
(0.9)
A
4
avr 4.6
(3)
2.8
(-3)
3.2
(-1.7)
3.2
(-1.7)
2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 71
1 2 3 4 5 6 range
A 2.6
(-3)
A
3.7
(-2.9)
A
2.9
(-3)
A
28.9
(-0.4)
A
46
(1.2)
A
63.9
(3)
A
61
B 4.8
(-2.8)
A
2.9
(-3)
A
3.5
(-2.9)
A
36.7
(-0.1)
A
72.9
(3)
A
67.4
(2.5)
A
70
C 2.3
(-3)
A
7.1
(-2.6)
A
7.3
(-2.6)
A
28.5
(-0.7)
A
36.3
(0)
A
70.2
(3)
M
68
avr 3.2
(-3)
4.6
(-2.9)
4.6
(-2.9)
31.4
(-0.4)
51.7
(1.5)
67.2
(3)
64
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193339_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2979
Sequence Type Exemplar sequence
Representative Public ID R05H5.4 NCBI
Target Description R05H5.4 /REP_DB=WormBase Gene ID /WP=CE02291 /TR=Q21764 /GB=CAA88727.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (FES-FPS subfamily)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063800(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_063800 NCBI Caenorhabditis elegans R05H5.4 (R05H5.4) mRNA, complete cds. 11/11 None
SNAP00000021969 ENSEMBL cdna:SNAP chromosome:CEL140:II:10198243:10199679:-1 11/11 None
GENEFINDER00000021976 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:10198243:10200726:-1 11/11 None
R05H5.4 ENSEMBL cdna:known chromosome:CEL140:II:10198243:10199679:-1 gene:R05H5.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10198239-10199676(-) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase (FES/FPS subfamily)
Ensembl R05H5.4
Entrez Gene 174581 Entrez gene
SwissProt Q21764 EMBL-EBI
WormBase CE02291 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88727 Hypothetical protein R05H5.4 [Caenorhabditis elegans] ref|NP_496201.1| R05H5.4 [Caenorhabditis elegans] 0.0
blast CAE57857 Hypothetical protein CBG00895 [Caenorhabditis briggsae] 1.0E-167
blast CAE57857 Hypothetical protein CBG00895 [Caenorhabditis briggsae] 1.0E-166
blast AAF98610 Hypothetical protein C18H7.4 [Caenorhabditis elegans] ref|NP_499953.1| C18H7.4 [Caenorhabditis elegans] 1.0E-151
Protein Families
Method ID Description E-Value
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 2.0E-16
hanks 1.4.8 AGC group; AGC IV GPCR kinases; DmGPRK2 2.0E-52
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 6.2E-65
Pfam IPR007290 EMBL-EBI Arv1-like protein 8.6E-110
Pfam IPR000719 EMBL-EBI Protein kinase 6.2E-65
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000021976 3 121-143,158-180,214-236
Sequence
Target Sequence
>C. ELEGANS:193339_S_AT
ttccgacacgcgtcaagtacacctacatggctgcttgtggcatggattacctgcacaaaa
agaactgtatccatcgtgatatcgcgtcgcgaaactgcctcattcacaagggagtcgtca
agatggctgactttggaatgtgccgagcccaatccgtctacaaagttgatcttaaaaagc
catgcaacatccgatggctggctcccgaggtttgggacaacggggaaacgcgtttcaaca
ctgacgtctacgcgtttggaatcatgatgtgggagtttttcgagaccccattcaagtcgc
catatgttgagatgaaagctgctcaagtcaagcgcaaaacccgagccggatatcgcctcc
ctccaccaccatcaatgccgagtagaatggtggaaatcatgagcgagtgctggcaagtag
atgctgaaaaacgaccaaccgctgaagagttgaaggaaaagctggaagagttcaagaaga
aaacggaaaactccatcactacttcggcaccacctacaagtgtggaaaaatcgaaattgt
ccgtgtcgtcagagccaaccacga


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
TTCCGACACGCGTCAAGTACACCTA 76 687 662 Antisense
GTACACCTACATGGCTGCTTGTGGC 141 461 678 Antisense
ATATCGCGTCGCGAAACTGCCTCAT 359 21 740 Antisense
AGCCCAATCCGTCTACAAAGTTGAT 234 77 807 Antisense
CATGCAACATCCGATGGCTGGCTCC 183 211 842 Antisense
GCTGGCTCCCGAGGTTTGGGACAAC 569 293 858 Antisense
GGAAACGCGTTTCAACACTGACGTC 265 527 885 Antisense
CAACACTGACGTCTACGCGTTTGGA 243 187 897 Antisense
ACCCCATTCAAGTCGCCATATGTTG 456 89 946 Antisense
GCAAAACCCGAGCCGGATATCGCCT 624 317 995 Antisense
TCCGTGTCGTCAGAGCCAACCACGA 123 595 1201 Antisense
Sequence Source Affymetrix Proprietary Database