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[193329_at] cysteine protease and a protease inhibitor

Description F41E6.6 /REP_DB=WormBase Gene ID /WP=CE10254 /TR=O16454 /GB=AAB65956.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=cysteine protease and a protease inhibitor
Cluster 6grp_highest_10_10 > 27      6grp_high1_10_10 > 61      4grp_highest_8_8 > 39      4grp_high_8_8 > 04      6grp_highest_nonorm > 34      6grp_total > 61      4grp_total > 04      6grp_highest_sub > 03_04      6grp_cgc > 93      6grp_high1_sub > 04      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4350
1 2 3 4 range
A 2014.7
(-1)
P 		1364
(-2.3)
P 		974.5
(-3)
P 		4168.9
(3)
P 		3194
B 2364.8
(-1.3)
P 		1174
(-3)
P 		1168.2
(-3)
P 		5324.7
(3)
P 		4157
C 2102
(-1.4)
P 		1093.1
(-3)
P 		1198.1
(-2.8)
P 		4870.5
(3)
P 		3777
avr 2160.5
(-1.3) 		1210.4
(-2.8) 		1113.6
(-3) 		4788
(3) 		3674

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2247
1 2 3 4 5 6 range
A 1947.1
(-2.2)
P 		2266.2
(-1.3)
P 		3829.3
(2.9)
P 		3883.3
(3)
P 		2466.1
(-0.8)
P 		1636.6
(-3)
P 		2247
B 2069.5
(-1.7)
P 		2217.6
(-1.1)
P 		3231.5
(3)
P 		3177.2
(2.8)
P 		2226.5
(-1.1)
P 		1745.7
(-3)
P 		1486
C 1967.7
(-3)
P 		2506
(-1.1)
P 		3668.2
(3)
P 		3677
(3)
P 		2011.7
(-2.8)
P 		1958.2
(-3)
P 		1719
avr 1994.8
(-2.3) 		2329.9
(-1.2) 		3576.3
(3) 		3579.2
(3) 		2234.8
(-1.5) 		1780.2
(-3) 		1799
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 880
1 2 3 4 range
A 733.6
(3)
P 		296.1
(-2.5)
P 		254.8
(-3)
P 		610.2
(1.5)
P 		479
B 754.1
(0.4)
P 		289.9
(-2.9)
P 		270.7
(-3)
P 		1134.7
(3)
P 		864
C 695.8
(1.5)
P 		314.3
(-3)
P 		417.6
(-1.8)
P 		821.2
(3)
P 		507
avr 727.8
(1.6) 		300.1
(-3) 		314.4
(-2.8) 		855.4
(3) 		555

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 626
1 2 3 4 5 6 range
A 358.9
(-3)
P 		806
(1.3)
P 		834
(1.6)
P 		984.9
(3)
P 		744.2
(0.7)
P 		398.5
(-2.6)
P 		626
B 720.1
(-1.4)
P 		738.1
(-0.9)
P 		784.7
(0.2)
P 		841.5
(1.5)
P 		904.6
(3)
P 		651
(-3)
P 		254
C 729.3
(-1.3)
P 		764.7
(-0.6)
P 		933.6
(3)
P 		739.5
(-1.1)
P 		651
(-3)
P 		655.5
(-2.9)
P 		283
avr 602.8
(-2.3) 		769.6
(1.2) 		850.8
(2.9) 		855.3
(3) 		766.6
(1.1) 		568.3
(-3) 		287
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193329_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11944
Sequence Type Exemplar sequence
Representative Public ID F41E6.6 NCBI
Target Description F41E6.6 /REP_DB=WormBase Gene ID /WP=CE10254 /TR=O16454 /GB=AAB65956.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=cysteine protease and a protease inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072814(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072814 NCBI Caenorhabditis elegans F41E6.6 (F41E6.6) mRNA, complete cds. 11/11 None
SNAP00000009419 ENSEMBL cdna:SNAP chromosome:CEL140:V:8597507:8599938:1 11/11 None
GENEFINDER00000009435 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8597507:8599938:1 11/11 None
F41E6.6.2 ENSEMBL cdna:known chromosome:CEL140:V:8597500:8600088:1 gene:F41E6.6 11/11 None
F41E6.6.1 ENSEMBL cdna:known chromosome:CEL140:V:8597502:8600088:1 gene:F41E6.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8597507-8599939(+) 100.0 100.0
Public Domain and Genome References
Gene Title cysteine protease and a protease inhibitor
Ensembl F41E6.6
Entrez Gene 179240 Entrez gene
SwissProt O16454 EMBL-EBI
WormBase CE35305 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:20225_AT cysteine proteinase, putative at
ATH1-121501:251838_AT cysteine proteinase, putative at
CANINE:1604295_AT similar to Cathepsin F precursor (CATSF) cfa
CANINE:1590162_S_AT similar to Cathepsin F precursor (CATSF) cfa
CANINE:1590161_AT similar to Cathepsin F precursor (CATSF) cfa
CANINE:1583457_AT similar to Cathepsin F precursor (CATSF) cfa
CANINE_2:CFA.12703.1.A1_S_AT similar to Cathepsin F precursor (CATSF) cfa
CANINE_2:CFA.4333.1.A1_AT similar to Cathepsin F precursor (CATSF) cfa
CANINE_2:CFAAFFX.19291.1.S1_AT similar to Cathepsin F precursor (CATSF) cfa
CANINE_2:CFAAFFX.19291.1.S1_S_AT similar to Cathepsin F precursor (CATSF) cfa
DROSOPHILA_2:1627566_A_AT dm
DROSGENOME1:151801_AT dm
HG-U133_PLUS_2:203657_S_AT cathepsin F hs
HG-U133A:203657_S_AT cathepsin F hs
HG-FOCUS:203657_S_AT cathepsin F hs
HG-U133A_2:203657_S_AT cathepsin F hs
HU35KSUBA:RC_AA478441_AT cathepsin F hs
HU35KSUBA:T08879_AT cathepsin F hs
U133_X3P:G6042195_3P_A_AT cathepsin F hs
HG-U95AV2:39846_AT cathepsin F hs
HG-U95D:86110_AT cathepsin F hs
HU35KSUBC:RC_D45644_AT Cathepsin F hs
MG-U74AV2:97336_AT cathepsin F mm
MG-U74BV2:164427_F_AT cathepsin F mm
MOE430A:1451019_AT cathepsin F mm
MOUSE430A_2:1451019_AT cathepsin F mm
MOUSE430_2:1451019_AT cathepsin F mm
MOUSE430_2:1449794_X_AT Cathepsin F, mRNA (cDNA clone MGC:7707 IMAGE:3497695) mm
MOE430B:1449794_X_AT Cathepsin F, mRNA (cDNA clone MGC:7707 IMAGE:3497695) mm
MU19KSUBA:TC19735_AT Cathepsin F, mRNA (cDNA clone MGC:7707 IMAGE:3497695) mm
MU19KSUBA:TC20125_AT Cathepsin F, mRNA (cDNA clone MGC:7707 IMAGE:3497695) mm
MU19KSUBA:TC20125_G_AT Cathepsin F, mRNA (cDNA clone MGC:7707 IMAGE:3497695) mm
MU19KSUBC:TC36006_AT Cathepsin F, mRNA (cDNA clone MGC:7707 IMAGE:3497695) mm
MU19KSUBC:TC36007_AT Cathepsin F, mRNA (cDNA clone MGC:7707 IMAGE:3497695) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
4869 cysteine protease inhibitor activity inferred from electronic annotation QuickGO AmiGO
8234 cysteine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB65956 Hypothetical protein F41E6.6 [Caenorhabditis elegans] ref|NP_505215.2| F41E6.6 [Caenorhabditis elegans] 0.0
blast CAE58359 Hypothetical protein CBG01480 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000010 EMBL-EBI Cysteine protease inhibitor 1.3E-8
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 1.5E-122
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 2.9E-118
Sequence
Target Sequence 
>C. ELEGANS:193329_AT
ggaaggagcatggttcattgccaagaacaagcttgtatcactttcagaacaagaacttgt
ggattgtgatagtatggatcagggatgtaatggaggattgccaagtaatgcatacaaaat
tggaaagtttgtcgtatcagataattactgttttttagttttttatcataaaaccacaaa
agagatcatccgtatgggtggcttggagccagaagatgcatatccatatgatggaagagg
tgaaacatgtcatttggtgagaaaggacattgctgtgtatatcaacggatcagttgagct
gccacacgatgaagttgaaatgcaaaagtggcttgtcaccaagggaccaatttctatcgg
tctcaacgcaaacactctccaattctaccgtcacggtgttgtccatccattcaaaatctt
ctgcgagccatttatgcttaaccatggtgttttgattgttggatacggaaaagatggtcg
caagccatattggattgtca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAAGGAGCATGGTTCATTGCCAAG 78 533 903 Antisense
AGAACAAGCTTGTATCACTTTCAGA 454 73 926 Antisense
GAGATCATCCGTATGGGTGGCTTGG 205 397 1084 Antisense
GGATCAGTTGAGCTGCCACACGATG 599 511 1189 Antisense
AGTGGCTTGTCACCAAGGGACCAAT 399 57 1229 Antisense
TCTATCGGTCTCAACGCAAACACTC 594 613 1255 Antisense
TCTCCAATTCTACCGTCACGGTGTT 538 607 1278 Antisense
ACGGTGTTGTCCATCCATTCAAAAT 93 93 1295 Antisense
CCATTCAAAATCTTCTGCGAGCCAT 656 269 1309 Antisense
TGCGAGCCATTTATGCTTAACCATG 148 585 1324 Antisense
GGTCGCAAGCCATATTGGATTGTCA 322 501 1378 Antisense
Sequence Source Affymetrix Proprietary Database