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[193302_at] Leucine Rich Repeat (2 copies) (2 domains)

Description K08E7.8 /REP_DB=WormBase Gene ID /WP=CE11930 /TR=Q21347 /GB=CAB01231.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies) (2 domains)
Cluster 6grp_highest_10_10 > 16      6grp_high1_10_10 > 51      4grp_highest_8_8 > 03      4grp_high_8_8 > 38      6grp_highest_nonorm > 80      6grp_total > 61      4grp_total > 41      6grp_highest_sub > 03_04      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 242
1 2 3 4 range
A 86.8
(-3)
P 		320.7
(3)
P 		267.5
(1.6)
P 		180
(-0.6)
P 		234
B 102.1
(-3)
P 		282.3
(2.5)
P 		297
(3)
P 		190.9
(-0.3)
P 		195
C 78.3
(-3)
P 		296.2
(3)
P 		260.1
(2)
P 		235.5
(1.3)
P 		218
avr 89.1
(-3) 		299.7
(3) 		274.9
(2.3) 		202.1
(0.2) 		211

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 299
1 2 3 4 5 6 range
A 170.4
(-1.2)
P 		220.5
(-0.1)
P 		360.1
(3)
P 		343.3
(2.6)
P 		187.8
(-0.8)
P 		88.1
(-3)
P 		272
B 171.3
(-1.3)
P 		321.8
(2.4)
P 		348.4
(3)
P 		248.2
(0.6)
P 		187.1
(-0.9)
P 		101.2
(-3)
P 		247
C 185.1
(-1.2)
P 		308.7
(1.4)
P 		307.3
(1.3)
P 		387.3
(3)
P 		254.9
(0.3)
P 		96.7
(-3)
P 		291
avr 175.6
(-1) 		283.7
(1.6) 		338.6
(3) 		326.3
(2.7) 		209.9
(-0.2) 		95.3
(-3) 		243
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 65
1 2 3 4 range
A 31.6
(-2.3)
P 		69.6
(3)
P 		69.9
(3)
P 		26.3
(-3)
P 		44
B 32.6
(-3)
P 		69.7
(3)
P 		68.8
(2.9)
P 		40.7
(-1.7)
P 		37
C 25.9
(-3)
P 		85.2
(2.5)
P 		90.7
(3)
P 		39.7
(-1.7)
P 		65
avr 30
(-3) 		74.8
(2.8) 		76.5
(3) 		35.6
(-2.3) 		47

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 86
1 2 3 4 5 6 range
A 31.4
(-2.1)
P 		78.4
(2.2)
P 		78.4
(2.2)
P 		87.1
(3)
P 		56.7
(0.2)
P 		21.4
(-3)
P 		66
B 59.6
(-1.1)
P 		107.1
(3)
P 		84.6
(1.1)
P 		65.8
(-0.6)
P 		76
(0.3)
P 		37.8
(-3)
P 		69
C 68.6
(0.5)
P 		94.2
(3)
P 		78.2
(1.4)
P 		77.9
(1.4)
P 		82.5
(1.9)
P 		32.4
(-3)
P 		62
avr 53.2
(-0.8) 		93.2
(3) 		80.4
(1.8) 		76.9
(1.4) 		71.7
(0.9) 		30.5
(-3) 		63
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193302_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9064
Sequence Type Exemplar sequence
Representative Public ID K08E7.8 NCBI
Target Description K08E7.8 /REP_DB=WormBase Gene ID /WP=CE11930 /TR=Q21347 /GB=CAB01231.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Leucine Rich Repeat (2 copies) (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070010(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070010 NCBI Caenorhabditis elegans K08E7.8 (K08E7.8) mRNA, complete cds. 11/11 None
SNAP00000042649 ENSEMBL cdna:SNAP chromosome:CEL140:IV:12585193:12586036:-1 11/11 None
GENEFINDER00000042659 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:12585193:12586036:-1 11/11 None
K08E7.8 ENSEMBL cdna:known chromosome:CEL140:IV:12585193:12586081:-1 gene:K08E7.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:12585198-12586042(-) 100.0 100.0
Public Domain and Genome References
Gene Title Leucine Rich Repeat (2 copies) (2 domains)
Ensembl K08E7.8
Entrez Gene 178213 Entrez gene
SwissProt Q21347 EMBL-EBI
WormBase CE11930 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1639439_AT dm
DROSGENOME1:141444_AT dm
Protein Similarities
Method ID Description E-Value
blast CAB01231 Hypothetical protein K08E7.8 [Caenorhabditis elegans] ref|NP_502411.1| K08E7.8 [Caenorhabditis elegans] 2.0E-75
blast CAE67915 Hypothetical protein CBG13512 [Caenorhabditis briggsae] 3.0E-20
blast AAF48118 CG2471-PA [Drosophila melanogaster] gb|AAL29110.1| LP11415p [Drosophila melanogaster] ref|NP_572770.1| CG2471-PA [Drosophila melanogaster] 3.0E-19
Protein Domains
Database ID Description E-Value
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0047
Sequence
Target Sequence 
>C. ELEGANS:193302_AT
atgtcaattgtaatgtcagccggcaaaggagtgactcaagtagtcgaacgatgtgaagct
gcaaaagaatccgggtttttggacctttcatcttgccagttaatgtacatggctgacgcg
gtgtacatgttaattaagggatacgaaatcacaaaagttagtattcaagataacggcttc
aaaaaattccccaaaaaatttgtgatcaaatttccaactgccactatcctaaatatggct
aacaatgaaatctctgaaattcccgaagaagttgccacgtggacaagtttgaaagggtta
aacgctgcgaagaacaagatttcaaagtttccggagccatttttacagctgaaaaatttg
atctacttggatctcaacggtaatcaacttgaagaaatcgacgtggatttgttctactca
tctttaccggcgctgataaagctgaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGTCAATTGTAATGTCAGCCGGCA 154 47 13 Antisense
TTGGACCTTTCATCTTGCCAGTTAA 572 703 91 Antisense
GTTAATGTACATGGCTGACGCGGTG 555 445 111 Antisense
GGCTGACGCGGTGTACATGTTAATT 602 539 123 Antisense
TTCCAACTGCCACTATCCTAAATAT 351 699 224 Antisense
GAAGTTGCCACGTGGACAAGTTTGA 493 335 280 Antisense
GTTTCCGGAGCCATTTTTACAGCTG 46 437 339 Antisense
ATCTACTTGGATCTCAACGGTAATC 516 25 373 Antisense
ATCGACGTGGATTTGTTCTACTCAT 151 37 409 Antisense
GGATTTGTTCTACTCATCTTTACCG 36 511 417 Antisense
TTTACCGGCGCTGATAAAGCTGAAC 473 559 435 Antisense
Sequence Source Affymetrix Proprietary Database