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[193287_s_at] BRCA1 C Terminus (BRCT) domain (4 domains)

Description F37D6.1 /REP_DB=WormBase Gene ID /WP=CE05818 /TR=Q20129 /GB=CAA99847.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=BRCA1 C Terminus (BRCT) domain (4 domains)
Cluster 6grp_highest_10_10 > 76      6grp_high1_10_10 > 76      6grp_highest_nonorm > 91      6grp_total > 67      4grp_total > 15      6grp_highest_sub > Da      6grp_cgc > 48      6grp_high1_sub > Da      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 78
1 2 3 4 range
A 123.5
(1.8)
P 		85.2
(-2.6)
A 		81.4
(-3)
P 		133.7
(3)
P 		52
B 134.3
(2.6)
P 		103.3
(-3)
A 		109.2
(-1.9)
P 		136.5
(3)
P 		33
C 148.5
(3)
P 		70.9
(-3)
A 		126.8
(1.3)
A 		123.4
(1.1)
P 		78
avr 135.4
(3) 		86.5
(-3) 		105.8
(-0.6) 		131.2
(2.5) 		49

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 148
1 2 3 4 5 6 range
A 151.1
(-1.9)
P 		125
(-3)
P 		160.2
(-1.5)
P 		149.9
(-1.9)
P 		157.3
(-1.6)
P 		266.3
(3)
P 		141
B 160.2
(-1.7)
P 		130.5
(-3)
P 		156.6
(-1.8)
P 		140.5
(-2.5)
P 		151.6
(-2)
P 		263.3
(3)
P 		133
C 118.6
(-3)
P 		168.9
(-0.6)
P 		145.6
(-1.7)
P 		186.2
(0.3)
P 		141.2
(-1.9)
P 		242.6
(3)
P 		124
avr 143.3
(-2.9) 		141.5
(-3) 		154.1
(-2.3) 		158.9
(-2.1) 		150
(-2.6) 		257.4
(3) 		116
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 31
1 2 3 4 range
A 45
(3)
P 		18.5
(-3)
A 		21.3
(-2.4)
P 		19.6
(-2.8)
P 		27
B 42.8
(3)
P 		25.5
(-2.9)
A 		25.3
(-3)
P 		29.1
(-1.7)
P 		18
C 49.1
(3)
P 		20.4
(-3)
A 		44.2
(2)
A 		20.8
(-2.9)
P 		29
avr 45.6
(3) 		21.5
(-3) 		30.3
(-0.8) 		23.2
(-2.6) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 70
1 2 3 4 5 6 range
A 27.9
(-3)
P 		44.5
(-0.3)
P 		34.9
(-1.9)
P 		38
(-1.4)
P 		47.5
(0.2)
P 		64.8
(3)
P 		37
B 55.7
(-1.2)
P 		43.4
(-2.4)
P 		38
(-2.9)
P 		37.2
(-3)
P 		61.6
(-0.6)
P 		98.2
(3)
P 		61
C 44
(-2.1)
P 		51.5
(-1)
P 		37.1
(-3)
P 		37.4
(-3)
P 		45.7
(-1.8)
P 		81.2
(3)
P 		44
avr 42.5
(-2.2) 		46.5
(-1.7) 		36.7
(-3) 		37.5
(-2.9) 		51.6
(-1) 		81.4
(3) 		45
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193287_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.472
Sequence Type Exemplar sequence
Representative Public ID F37D6.1 NCBI
Target Description F37D6.1 /REP_DB=WormBase Gene ID /WP=CE05818 /TR=Q20129 /GB=CAA99847.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=BRCA1 C Terminus (BRCT) domain (4 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060342(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060342 NCBI Caenorhabditis elegans MUS (Drosophila mutagen sensitive) related family member (mus-101) (mus-101) mRNA, complete cds. 11/11 A 
SNAP00000007525 ENSEMBL cdna:SNAP chromosome:CEL140:I:10487541:10493084:-1 10/11 None
GENEFINDER00000007531 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:10487541:10493084:-1 11/11 None
F37D6.1 ENSEMBL cdna:known chromosome:CEL140:I:10487434:10493770:-1 gene:F37D6.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10487471-10493701(-) 100.0 100.0
Public Domain and Genome References
Gene Title BRCA1 C Terminus (BRCT) domain (4 domains)
Gene Symbol mus-101
Ensembl F37D6.1
Entrez Gene 172929 Entrez gene
SwissProt Q20129 EMBL-EBI
WormBase CE32652 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA99847 Hypothetical protein F37D6.1 [Caenorhabditis elegans] ref|NP_492743.2| MUS (Drosophila mutagen sensitive) related family member (mus-101) [Caenorhabditis elegans] 0.0
blast CAE58953 Hypothetical protein CBG02221 [Caenorhabditis briggsae] 0.0
blast AAQ22476 RE28166p [Drosophila melanogaster] 4.0E-27
blast AAQ22476 RE28166p [Drosophila melanogaster] 5.0E-27
Protein Domains
Database ID Description E-Value
Pfam IPR001357 EMBL-EBI BRCT 1.9E-14
Pfam IPR001357 EMBL-EBI BRCT 1.1E-7
Pfam IPR001357 EMBL-EBI BRCT 1.5E-13
Pfam IPR001357 EMBL-EBI BRCT 1.7E-5
Pfam IPR001357 EMBL-EBI BRCT 2.2E-5
Pfam IPR001357 EMBL-EBI BRCT 7.7E-10
Pfam IPR001357 EMBL-EBI BRCT 0.0043
Pfam IPR001357 EMBL-EBI BRCT 1.5E-13
Pfam IPR001357 EMBL-EBI BRCT 1.7E-5
Pfam IPR001357 EMBL-EBI BRCT 2.2E-5
Pfam IPR001357 EMBL-EBI BRCT 7.7E-10
Pfam IPR001357 EMBL-EBI BRCT 1.9E-14
Pfam IPR001357 EMBL-EBI BRCT 1.1E-7
Pfam IPR001357 EMBL-EBI BRCT 1.5E-13
Pfam IPR001357 EMBL-EBI BRCT 1.7E-5
Pfam IPR001357 EMBL-EBI BRCT 2.2E-5
Pfam IPR001357 EMBL-EBI BRCT 7.7E-10
Sequence
Target Sequence 
>C. ELEGANS:193287_S_AT
gtgactcatctgattgcgagcaacatgcaaagagctccaaaagttctttgctcaattgca
gctggaaaatggtgtctaacacctgattatgtgactaaaagtgctgaagttggtcgatgg
ctcgatgaaaaatcatttgagtggactcgagaaaagttgttggcgtgttcgaaaaagaac
gagtccctcaaagaacgagatagtcggaaagtttccgagaatctagcagctgtttgtgga
ttatggaggcaacgtgtggcagagatgccggttacattttcagttagcatggagaatcgt
caaaatggagcattctcggattggcgttgcgtaattcatctcgacgataagagagctggc
gtattttcatcgattctggaagccggtggtgccattgttcattcgatttcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGACTCATCTGATTGCGAGCAACA 320 483 3049 Antisense
AGTTCTTTGCTCAATTGCAGCTGGA 38 65 3090 Antisense
GTGCTGAAGTTGGTCGATGGCTCGA 675 477 3149 Antisense
AGTTTCCGAGAATCTAGCAGCTGTT 613 61 3258 Antisense
ATGGAGGCAACGTGTGGCAGAGATG 435 51 3291 Antisense
GATGCCGGTTACATTTTCAGTTAGC 359 415 3312 Antisense
GAGCATTCTCGGATTGGCGTTGCGT 432 389 3356 Antisense
GGCGTTGCGTAATTCATCTCGACGA 582 541 3371 Antisense
GAGCTGGCGTATTTTCATCGATTCT 220 387 3401 Antisense
GATTCTGGAAGCCGGTGGTGCCATT 218 431 3420 Antisense
TGGTGCCATTGTTCATTCGATTTCC 145 553 3435 Antisense
Sequence Source Affymetrix Proprietary Database