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[193282_at] GDA1/CD39 (nucleoside phosphatase) family

Description K08H10.4 /REP_DB=WormBase Gene ID /WP=CE18877 /TR=Q9XU84 /GB=CAB05544.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=GDA1-CD39 (nucleoside phosphatase) family
Cluster 6grp_highest_10_10 > 38      6grp_high1_10_10 > 72      4grp_highest_8_8 > 22      4grp_high_8_8 > 06      6grp_highest_nonorm > 55      6grp_total > 73      4grp_total > 02      6grp_highest_sub > 04      6grp_cgc > 76      6grp_high1_sub > 04      6grp_cgc_sub > 03_04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3081
1 2 3 4 range
A 1039.6
(-3)
P 		1076.4
(-2.9)
P 		1191.5
(-2.7)
P 		4112.6
(3)
P 		3073
B 1087.6
(-3)
P 		1100.3
(-3)
P 		1089
(-3)
P 		3946.8
(3)
P 		2859
C 1031.2
(-3)
P 		1197.8
(-2.5)
P 		1230.3
(-2.4)
P 		3190.2
(3)
P 		2159
avr 1052.8
(-3) 		1124.8
(-2.8) 		1170.3
(-2.7) 		3749.9
(3) 		2697

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1001
1 2 3 4 5 6 range
A 1092.6
(-3)
P 		1670.3
(1.2)
P 		1725.3
(1.6)
P 		1921.6
(3)
P 		1765.8
(1.9)
P 		1632.1
(0.9)
P 		829
B 1162.8
(-3)
P 		1619.7
(0.4)
P 		1972.4
(3)
P 		1851
(2.1)
P 		1667.7
(0.7)
P 		1751.1
(1.4)
P 		810
C 1023.7
(-3)
P 		1410.2
(-0.7)
P 		1853.6
(2)
P 		2025
(3)
P 		1867.6
(2.1)
P 		1801.3
(1.7)
P 		1001
avr 1093
(-3) 		1566.7
(0.4) 		1850.4
(2.4) 		1932.5
(3) 		1767
(1.8) 		1728.2
(1.5) 		840
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 607
1 2 3 4 range
A 378.5
(-0.6)
P 		233.7
(-3)
P 		311.5
(-1.7)
P 		602
(3)
P 		368
B 346.8
(-2)
P 		271.8
(-2.8)
P 		252.3
(-3)
P 		841.1
(3)
P 		589
C 341.4
(-3)
P 		344.4
(-2.9)
P 		428.8
(-0.3)
P 		537.9
(3)
P 		197
avr 355.6
(-1.8) 		283.3
(-3) 		330.9
(-2.2) 		660.3
(3) 		377

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 476
1 2 3 4 5 6 range
A 201.4
(-3)
P 		594.1
(3)
P 		375.7
(-0.3)
P 		487.4
(1.4)
P 		532.8
(2.1)
P 		397.4
(-0)
P 		393
B 404.6
(-3)
P 		539.1
(-0)
P 		479
(-1.4)
P 		490.3
(-1.1)
P 		677.6
(3)
P 		653
(2.5)
P 		273
C 379.4
(-3)
P 		430.3
(-1.6)
P 		471.8
(-0.5)
P 		407.2
(-2.3)
P 		604.3
(3)
P 		603
(3)
P 		225
avr 328.5
(-3) 		521.2
(1.2) 		442.2
(-0.5) 		461.6
(-0.1) 		604.9
(3) 		551.1
(1.8) 		276
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193282_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11370
Sequence Type Exemplar sequence
Representative Public ID K08H10.4 NCBI
Target Description K08H10.4 /REP_DB=WormBase Gene ID /WP=CE18877 /TR=Q9XU84 /GB=CAB05544.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=GDA1-CD39 (nucleoside phosphatase) family
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073172(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073172 NCBI Caenorhabditis elegans Uridine DiPhosphatase family member (uda-1) (uda-1) mRNA, complete cds. 11/11 None
SNAP00000005154 ENSEMBL cdna:SNAP chromosome:CEL140:V:10007982:10009841:1 11/11 None
GENEFINDER00000005159 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10007550:10009841:1 11/11 None
K08H10.4.2 ENSEMBL cdna:known chromosome:CEL140:V:10007335:10010064:1 gene:K08H10.4 11/11 None
K08H10.4.1 ENSEMBL cdna:known chromosome:CEL140:V:10007337:10010064:1 gene:K08H10.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10007549-10009841(+) 100.0 100.0
Public Domain and Genome References
Gene Title GDA1/CD39 (nucleoside phosphatase) family
Gene Symbol uda-1
Ensembl K08H10.4
Entrez Gene 179395 Entrez gene
SwissProt Q9XU84 EMBL-EBI
WormBase CE18877 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17578_AT apyrase (APY1) at
ATH1-121501:258567_AT apyrase (APY1) at
CANINE:1597018_AT similar to Ectonucleoside triphosphate diphosphohydrolase 5 precursor (NTPDase5) (Nucleoside diphosphatase) (CD39 antigen-like 4) (ER-UDPase) cfa
CANINE_2:CFA.20908.1.A1_AT similar to Ectonucleoside triphosphate diphosphohydrolase 5 precursor (NTPDase5) (Nucleoside diphosphatase) (CD39 antigen-like 4) (ER-UDPase) cfa
CANINE_2:CFAAFFX.397.1.S1_AT similar to Ectonucleoside triphosphate diphosphohydrolase 5 precursor (NTPDase5) (Nucleoside diphosphatase) (CD39 antigen-like 4) (ER-UDPase) cfa
DROSOPHILA_2:1630857_S_AT dm
DROSGENOME1:153738_AT dm
CHICKEN:GGA.13745.1.A1_AT ectonucleoside triphosphate diphosphohydrolase 5 gga
CHICKEN:GGA.9865.1.S1_AT ectonucleoside triphosphate diphosphohydrolase 5 gga
HG-U133_PLUS_2:205757_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
HG-U133A:205757_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
HG-FOCUS:205757_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
HG-U133A_2:205757_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
HU35KSUBC:RC_AA255903_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
U133_X3P:G4557426_3P_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
U133_X3P:HS2.80975.2.A1_3P_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
HG-U133_PLUS_2:1554094_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
HG-U95AV2:40666_AT ectonucleoside triphosphate diphosphohydrolase 5 hs
MOE430A:1451765_A_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430_2:1451765_A_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430A_2:1451765_A_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MG-U74AV2:92561_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MG-U74CV2:133939_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MG-U74CV2:166594_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MG-U74CV2:169945_R_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOE430A:1417382_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430A_2:1417382_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430_2:1417382_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOE430A:1417383_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430A_2:1417383_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430_2:1417383_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOE430A:1417384_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430A_2:1417384_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430_2:1417384_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOE430B:1433763_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430_2:1433763_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOE430B:1458677_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MOUSE430_2:1458677_AT ectonucleoside triphosphate diphosphohydrolase 5 mm
MU19KSUBA:TC17052_AT Ectonucleoside triphosphate diphosphohydrolase 5, mRNA (cDNA clone MGC:18322 IMAGE:4242560) mm
MU19KSUBB:TC28715_AT Ectonucleoside triphosphate diphosphohydrolase 5, mRNA (cDNA clone MGC:18322 IMAGE:4242560) mm
MU19KSUBB:TC28715_G_AT Ectonucleoside triphosphate diphosphohydrolase 5, mRNA (cDNA clone MGC:18322 IMAGE:4242560) mm
MU19KSUBB:TC34009_AT Ectonucleoside triphosphate diphosphohydrolase 5, mRNA (cDNA clone MGC:18322 IMAGE:4242560) mm
RG-U34C:RC_AI236668_AT ectonucleoside triphosphate diphosphohydrolase 5 rn
RAE230B:1382434_AT ectonucleoside triphosphate diphosphohydrolase 5 rn
RAT230_2:1382434_AT ectonucleoside triphosphate diphosphohydrolase 5 rn
YEAST_2:1780001_AT Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16787 hydrolase activity inferred from electronic annotation QuickGO AmiGO
16829 lyase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05544 Hypothetical protein K08H10.4 [Caenorhabditis elegans] ref|NP_505573.1| Uridine DiPhosphatase family member (uda-1) [Caenorhabditis elegans] 0.0
blast CAE66294 Hypothetical protein CBG11542 [Caenorhabditis briggsae] 1.0E-154
Protein Domains
Database ID Description E-Value
Pfam IPR000407 EMBL-EBI Nucleoside phosphatase GDA1/CD39 7.9E-51
Pfam IPR000407 EMBL-EBI Nucleoside phosphatase GDA1/CD39 3.1E-6
Pfam IPR000407 EMBL-EBI Nucleoside phosphatase GDA1/CD39 6.6E-39
Pfam IPR000407 EMBL-EBI Nucleoside phosphatase GDA1/CD39 3.1E-6
Sequence
Target Sequence 
>C. ELEGANS:193282_AT
catcgcactccttcgaaagttgctatggtaccacaaagaattttgtagaatccagtgaaa
tcatgcatttgcgagaattgaagggatctccagtttatttattctcgtacttctttgatc
gtgctttgaacagtggacttgttaaaggaaacgaaggtggaaagatcgagttgaggcaat
tcaaagaagctgcggaaattgcttgccgaagggaaaaaactgaaatcgacgatggaagtc
actggatgccttggcagtgtcttgatttgacatatatttactctctgttgcgagatggat
atcagttcgaagataatcagcctctcgtgttggccaagaaaataaaaggaatggaggttt
catggggacaaggacttgcatttgcaactgccaacgagtttcagctaacagaaggagcaa
tcaaaactgcactctcatcggaaccaaactctacagta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATCGCACTCCTTCGAAAGTTGCTA 688 211 920 Antisense
GGATCTCCAGTTTATTTATTCTCGT 558 511 1003 Antisense
TTCTCGTACTTCTTTGATCGTGCTT 123 691 1021 Antisense
GAAGCTGCGGAAATTGCTTGCCGAA 405 343 1105 Antisense
GATGGAAGTCACTGGATGCCTTGGC 259 407 1150 Antisense
GATGCCTTGGCAGTGTCTTGATTTG 255 415 1164 Antisense
GACATATATTTACTCTCTGTTGCGA 269 371 1188 Antisense
AGATAATCAGCCTCTCGTGTTGGCC 239 65 1230 Antisense
CTTGCATTTGCAACTGCCAACGAGT 353 217 1294 Antisense
AATCAAAACTGCACTCTCATCGGAA 601 171 1338 Antisense
CTCATCGGAACCAAACTCTACAGTA 439 227 1353 Antisense
Sequence Source Affymetrix Proprietary Database