[Home] | [Total List]

[193236_at] 6-pyruvoyl tetrahydrobioterin synthase

Description B0041.6 /REP_DB=WormBase Gene ID /WP=CE07671 /TR=SW:O02058 /GB=AAC24255.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=6-pyruvoyl tetrahydrobioterin synthase
Cluster 6grp_highest_10_10 > 06      6grp_high1_10_10 > 51      4grp_highest_8_8 > 19      4grp_high_8_8 > 63      6grp_highest_nonorm > 71      6grp_total > 51      4grp_total > 56      6grp_highest_sub > 04      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 100
1 2 3 4 range
A 180.4
(-2.9)
P 		197.9
(-1.5)
P 		252.9
(3)
P 		179.7
(-3)
P 		73
B 152.6
(-3)
P 		191.9
(3)
P 		170.1
(-0.3)
P 		169.6
(-0.4)
P 		39
C 197.6
(-0.2)
P 		155.3
(-3)
P 		245
(3)
P 		203.5
(0.2)
P 		90
avr 176.9
(-3) 		181.7
(-2.4) 		222.7
(3) 		184.3
(-2) 		46

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 423
1 2 3 4 5 6 range
A 237.3
(-1.4)
P 		292.6
(-0.6)
P 		549.1
(3)
P 		416.7
(1.1)
P 		257
(-1.1)
P 		126.2
(-3)
P 		423
B 350.8
(0.2)
P 		491.4
(3)
P 		457.6
(2.3)
P 		357.2
(0.3)
P 		369.2
(0.6)
P 		189.4
(-3)
P 		302
C 310.8
(-1.1)
P 		418.9
(0.8)
P 		382.9
(0.2)
P 		538.5
(3)
P 		295.6
(-1.4)
P 		206.8
(-3)
P 		332
avr 299.6
(-0.4) 		401
(1.7) 		463.2
(3) 		437.5
(2.5) 		307.3
(-0.2) 		174.1
(-3) 		289
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 59
1 2 3 4 range
A 65.7
(2.9)
P 		43
(-0.5)
P 		66.1
(3)
P 		26.3
(-3)
P 		40
B 48.7
(3)
P 		47.4
(2.4)
P 		39.4
(-1.4)
P 		36.1
(-3)
P 		13
C 65.4
(0.7)
P 		44.7
(-1.8)
P 		85.4
(3)
P 		34.3
(-3)
P 		51
avr 59.9
(2.3) 		45
(-0.6) 		63.6
(3) 		32.2
(-3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 133
1 2 3 4 5 6 range
A 43.7
(-2.1)
P 		104.1
(2)
P 		119.6
(3)
P 		105.7
(2.1)
P 		77.6
(0.2)
P 		30.7
(-3)
P 		89
B 122.1
(0.3)
P 		163.6
(3)
P 		111.1
(-0.4)
P 		94.6
(-1.5)
P 		150
(2.1)
P 		70.6
(-3)
P 		93
C 115.2
(1.7)
P 		127.8
(3)
P 		97.5
(-0.1)
P 		108.3
(1)
P 		95.7
(-0.3)
P 		69.2
(-3)
P 		59
avr 93.7
(-0) 		131.8
(3) 		109.4
(1.2) 		102.9
(0.7) 		107.8
(1.1) 		56.8
(-3) 		75
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193236_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1915
Sequence Type Exemplar sequence
Representative Public ID B0041.6 NCBI
Target Description B0041.6 /REP_DB=WormBase Gene ID /WP=CE07671 /TR=SW:O02058 /GB=AAC24255.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=6-pyruvoyl tetrahydrobioterin synthase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059018(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059018 NCBI Caenorhabditis elegans B0041.6 (B0041.6) mRNA, complete cds. 10/11 None
GENEFINDER00000016547 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:4651041:4652898:-1 11/11 None
SNAP00000016534 ENSEMBL cdna:SNAP chromosome:CEL140:I:4652187:4652898:-1 10/11 None
B0041.6 ENSEMBL cdna:known chromosome:CEL140:I:4652187:4652907:-1 gene:B0041.6 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:4652186-4652907(-) 100.0 100.0
Public Domain and Genome References
Gene Title 6-pyruvoyl tetrahydrobioterin synthase
Ensembl B0041.6
Entrez Gene 181823 Entrez gene
SwissProt O02058 EMBL-EBI
WormBase CE34237 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.18193.1.S1_AT similar to 6-pyruvoyl tetrahydrobiopterin synthase precursor (PTPS) (PTP synthase) cfa
CANINE_2:CFAAFFX.21477.1.S1_S_AT similar to 6-pyruvoyl tetrahydrobiopterin synthase precursor (PTPS) (PTP synthase) cfa
DROSOPHILA_2:1637036_S_AT purple dm
DROSGENOME1:153549_AT purple dm
CHICKEN:GGA.5120.3.S1_A_AT 6-pyruvoyltetrahydropterin synthase gga
HG-U133_PLUS_2:209694_AT 6-pyruvoyltetrahydropterin synthase hs
HG-U133A:209694_AT 6-pyruvoyltetrahydropterin synthase hs
HG-FOCUS:209694_AT 6-pyruvoyltetrahydropterin synthase hs
HG-U133A_2:209694_AT 6-pyruvoyltetrahydropterin synthase hs
HU35KSUBC:RC_AA449964_S_AT 6-pyruvoyltetrahydropterin synthase hs
HUGENEFL:D17400_AT 6-pyruvoyltetrahydropterin synthase hs
U133_X3P:G306438_3P_AT 6-pyruvoyltetrahydropterin synthase hs
HG-U95AV2:35697_AT 6-pyruvoyltetrahydropterin synthase hs
MG-U74AV2:160844_AT 6-pyruvoyl-tetrahydropterin synthase mm
MOE430A:1450660_AT 6-pyruvoyl-tetrahydropterin synthase mm
MOUSE430A_2:1450660_AT 6-pyruvoyl-tetrahydropterin synthase mm
MOUSE430_2:1450660_AT 6-pyruvoyl-tetrahydropterin synthase mm
MOE430B:1458402_AT 6-pyruvoyl-tetrahydropterin synthase mm
MOUSE430_2:1458402_AT 6-pyruvoyl-tetrahydropterin synthase mm
MG-U74BV2:116221_AT 6-pyruvoyl-tetrahydropterin synthase, mRNA (cDNA clone MGC:36014 IMAGE:5357873) mm
MU19KSUBA:TC22770_S_AT 6-pyruvoyl-tetrahydropterin synthase, mRNA (cDNA clone MGC:36014 IMAGE:5357873) mm
MU19KSUBB:TC31524_AT 6-pyruvoyl-tetrahydropterin synthase, mRNA (cDNA clone MGC:36014 IMAGE:5357873) mm
RG-U34A:M77850_AT 6-pyruvoyl-tetrahydropterin synthase rn
RAE230A:1369304_AT 6-pyruvoyl-tetrahydropterin synthase rn
RAT230_2:1369304_AT 6-pyruvoyl-tetrahydropterin synthase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6729 tetrahydrobiopterin biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3874 6-pyruvoyltetrahydropterin synthase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC24255 Hypothetical protein B0041.6 [Caenorhabditis elegans] ref|NP_491419.2| B0041.6 [Caenorhabditis elegans] sp|O02058|PTPS_CAEEL Putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (PTP synthase) 9.0E-77
blast AAC24255 Hypothetical protein B0041.6 [Caenorhabditis elegans] ref|NP_491419.2| B0041.6 [Caenorhabditis elegans] sp|O02058|PTPS_CAEEL Putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (PTP synthase) 6.0E-75
blast CAE74481 Hypothetical protein CBG22232 [Caenorhabditis briggsae] 5.0E-67
blast AAC24255 Hypothetical protein B0041.6 [Caenorhabditis elegans] ref|NP_491419.2| B0041.6 [Caenorhabditis elegans] sp|O02058|PTPS_CAEEL Putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (PTP synthase) 1.0E-54
blast CAE74481 Hypothetical protein CBG22232 [Caenorhabditis briggsae] 3.0E-48
blast AAN11065 CG16784-PC, isoform C [Drosophila melanogaster] gb|AAN11064.1| CG16784-PB, isoform B [Drosophila melanogaster] ref|NP_724244.1| CG16784-PC, isoform C [Drosophila melanogaster] ref|NP_599101.1| CG16784-PB, isoform B [Drosophila melanogaster] gb|AAL28626.1| LD05512p [Drosophila melanogaster] sp|P48611|PTPS_DROME 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (PTP synthase) (Sepiapterin synthase A) (Protein purple) gb|AAC47269.1| 6-pyruvoyltetrahydropterin synthase 3.0E-37
Protein Domains
Database ID Description E-Value
Pfam IPR007115 EMBL-EBI 6-pyruvoyl tetrahydropterin synthase and hypothetical protein 4.9E-123
Pfam IPR007115 EMBL-EBI 6-pyruvoyl tetrahydropterin synthase and hypothetical protein 3.5E-108
Pfam IPR007115 EMBL-EBI 6-pyruvoyl tetrahydropterin synthase and hypothetical protein 1.2E-121
Sequence
Target Sequence 
>C. ELEGANS:193236_AT
gaacgagtcgattcgttctccgcagcacatcgtcttcactctgaaaagctgagcgacgct
gaaaataaggaaacttttggaaaatgcaataattcaaatggtcatggacataattatgtt
tggaaggtaaagctccgcggagaagttgatccgacgagtggaatggtgtatgacctggca
aagctgaaaaaagaaatgagtttagtgctggatacgacaactgtgagcacatctgaaaac
gtggcaatttatatgttcgagaagctgaaatccgtaatgtcgaatccatcggttttgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACGAGTCGATTCGTTCTCCGCAG 701 347 40 Antisense
AGCACATCGTCTTCACTCTGAAAAG 259 77 63 Antisense
GTTTGGAAGGTAAAGCTCCGCGGAG 235 451 157 Antisense
GCTCCGCGGAGAAGTTGATCCGACG 294 299 171 Antisense
TGGTGTATGACCTGGCAAAGCTGAA 194 553 203 Antisense
AATGAGTTTAGTGCTGGATACGACA 32 161 234 Antisense
GGATACGACAACTGTGAGCACATCT 125 511 249 Antisense
GTGAGCACATCTGAAAACGTGGCAA 682 481 262 Antisense
ACGTGGCAATTTATATGTTCGAGAA 142 95 278 Antisense
GAGAAGCTGAAATCCGTAATGTCGA 421 391 298 Antisense
GTAATGTCGAATCCATCGGTTTTGT 311 461 313 Antisense
Sequence Source Affymetrix Proprietary Database