[Home] | [Total List]

[193234_at] phosphatidylcholine-sterol acyltransferase

Description M05B5.4 /REP_DB=WormBase Gene ID /WP=CE06190 /TR=Q21515 /GB=CAA95833.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=phosphatidylcholine-sterol acyltransferase
Cluster 6grp_highest_10_10 > 02      6grp_high1_10_10 > 01      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_highest_nonorm > 60      6grp_total > 08      4grp_total > 13      6grp_high1_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 843
1 2 3 4 range
A 635.4
(0.6)
P 		352.4
(-2.2)
P 		271.4
(-3)
P 		875.6
(3)
P 		604
B 706.7
(0.2)
P 		293.9
(-3)
P 		296.6
(-3)
P 		1062.4
(3)
P 		769
C 623.1
(0.9)
P 		299.4
(-2.2)
P 		219.5
(-3)
P 		834.5
(3)
P 		615
avr 655.1
(0.6) 		315.2
(-2.5) 		262.5
(-3) 		924.2
(3) 		662

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 412
1 2 3 4 5 6 range
A 609.2
(3)
P 		349
(-1.6)
P 		372.2
(-1.2)
P 		390.9
(-0.9)
P 		271.9
(-3)
P 		277.7
(-2.9)
P 		337
B 452.9
(3)
P 		321.7
(-0.1)
P 		415.9
(2.1)
P 		370.9
(1.1)
P 		323.6
(-0)
P 		197
(-3)
P 		256
C 436.6
(3)
P 		320.2
(-0.6)
P 		417.3
(2.4)
P 		355.9
(0.5)
P 		343
(0.1)
P 		240.9
(-3)
P 		196
avr 499.6
(3) 		330.3
(-0.9) 		401.8
(0.8) 		372.6
(0.1) 		312.8
(-1.3) 		238.5
(-3) 		261
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 163
1 2 3 4 range
A 231.3
(3)
P 		76.5
(-2.8)
P 		71
(-3)
P 		128.2
(-0.9)
P 		160
B 225.4
(3)
P 		72.6
(-2.9)
P 		68.7
(-3)
P 		226.4
(3)
P 		158
C 206.2
(3)
P 		86.1
(-2.6)
P 		76.5
(-3)
P 		140.7
(-0)
P 		130
avr 221
(3) 		78.4
(-2.7) 		72.1
(-3) 		165.1
(0.7) 		149

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 94
1 2 3 4 5 6 range
A 112.3
(1.7)
P 		124.1
(3)
P 		81.1
(-1.6)
P 		99.1
(0.3)
P 		82.1
(-1.5)
P 		67.6
(-3)
P 		57
B 157.6
(3)
P 		107.1
(-0.6)
P 		101
(-1)
P 		98.2
(-1.2)
P 		131.5
(1.1)
P 		73.5
(-3)
P 		84
C 161.8
(3)
P 		97.7
(-1.3)
P 		106.2
(-0.7)
P 		71.6
(-3)
P 		111
(-0.4)
P 		80.7
(-2.4)
P 		90
avr 143.9
(3) 		109.6
(0.1) 		96.1
(-1.1) 		89.6
(-1.7) 		108.2
(-0.1) 		73.9
(-3) 		70
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193234_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2514
Sequence Type Exemplar sequence
Representative Public ID M05B5.4 NCBI
Target Description M05B5.4 /REP_DB=WormBase Gene ID /WP=CE06190 /TR=Q21515 /GB=CAA95833.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=phosphatidylcholine-sterol acyltransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059632(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059632 NCBI Caenorhabditis elegans M05B5.4 (M05B5.4) mRNA, complete cds. 11/11 None
SNAP00000017390 ENSEMBL cdna:SNAP chromosome:CEL140:I:7196670:7198621:1 11/11 None
GENEFINDER00000017400 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7196670:7198621:1 11/11 None
M05B5.4 ENSEMBL cdna:known chromosome:CEL140:I:7196660:7198628:1 gene:M05B5.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7196600-7198552(+) 100.0 100.0
Public Domain and Genome References
Gene Title phosphatidylcholine-sterol acyltransferase
Ensembl M05B5.4
Entrez Gene 172457 Entrez gene
SwissProt Q21515 EMBL-EBI
WormBase CE06190 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:264442_AT lecithin:cholesterol acyltransferase family protein / LACT family protein at
ATGENOME1:14312_AT lecithin:cholesterol acyltransferase family protein / LACT family protein at
CANINE_2:CFA.102.1.S1_S_AT lysophospholipase 3 (lysosomal phospholipase A2) cfa
DROSOPHILA_2:1641570_S_AT dm
DROSOPHILA_2:1629877_AT dm
HG-U95AV2:32387_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
HU35KSUBB:RC_T16739_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
U133_X3P:HS.6770.0.S2_3P_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
HG-U133A_2:204458_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
HG-FOCUS:204458_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
HG-U133_PLUS_2:204458_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
HG-U133A:204458_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
HG-U95B:54062_AT lysophospholipase 3 (lysosomal phospholipase A2) hs
HG-U95D:78513_AT Lysophospholipase 3 (lysosomal phospholipase A2) hs
MOUSE430_2:1422341_S_AT lysophospholipase 3 mm
MOUSE430A_2:1422341_S_AT lysophospholipase 3 mm
MOE430A:1422341_S_AT lysophospholipase 3 mm
MU11KSUBB:MSA.15232.0_S_AT lysophospholipase 3 mm
MU11KSUBB:MSA.28418.0_AT lysophospholipase 3 mm
MG-U74BV2:106673_AT lysophospholipase 3 mm
MOE430A:1423704_AT lysophospholipase 3 mm
MOUSE430A_2:1423704_AT lysophospholipase 3 mm
MOUSE430_2:1423704_AT lysophospholipase 3 mm
MU19KSUBC:TC37385_AT Lysophospholipase 3 (Lypla3), mRNA mm
RG-U34C:RC_AI101159_AT lysosomal phospholipase A2 rn
RAE230A:1375034_AT lysosomal phospholipase A2 rn
RAT230_2:1375034_AT lysosomal phospholipase A2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6629 lipid metabolism inferred from electronic annotation QuickGO AmiGO
7018 microtubule-based movement inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5874 microtubule inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4607 phosphatidylcholine-sterol O-acyltransferase activity inferred from electronic annotation QuickGO AmiGO
5198 structural molecule activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA95833 Hypothetical protein M05B5.4 [Caenorhabditis elegans] ref|NP_492033.1| M05B5.4 [Caenorhabditis elegans] 0.0
blast CAE74248 Hypothetical protein CBG21934 [Caenorhabditis briggsae] 0.0
blast AAH93538 Unknown (protein for MGC:115275) [Xenopus laevis] 1.0E-94
Protein Domains
Database ID Description E-Value
Pfam IPR003386 EMBL-EBI Lecithin:cholesterol acyltransferase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:193234_AT
gttttgttagtttggcggctccatgggctggatcaatgcaaattgttcgattatttgcat
ctggatataatatgaattattatagagttattctaccaccgagtagcttgagagcaatgc
aaagatcattctcctcttcggcctttctgtttccaagtccagttgcatggaaaccacatg
aaatattagcgacaactgctgacaaaaactacactgttggaaatattaaagaattctttc
aagacattaattacatggttggatgggaacaatacaaacaggccgcccgtctgaatggaa
atttaagttctccaggagttccagttcattgtatttatggaacaggagtccccacaccgg
aaaagttttcatgggctcccggatactttccagattatccaccaactgaattcatgggtg
atggagacgggacagtgaacaaaaaatcagctacagtgtgcactaattggattggaaata
ataatggttataaggttactgtacacgaagtatttcaagctgatcacatggcaattctta
aac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTTTGTTAGTTTGGCGGCTCCATG 352 447 674 Antisense
CGGCTCCATGGGCTGGATCAATGCA 166 241 689 Antisense
GAGTTATTCTACCACCGAGTAGCTT 371 397 758 Antisense
AATGCAAAGATCATTCTCCTCTTCG 197 165 789 Antisense
CCTTTCTGTTTCCAAGTCCAGTTGC 177 269 815 Antisense
GGGAACAATACAAACAGGCCGCCCG 667 493 938 Antisense
GGCCGCCCGTCTGAATGGAAATTTA 368 541 954 Antisense
AGTTCTCCAGGAGTTCCAGTTCATT 113 65 979 Antisense
AGTTTTCATGGGCTCCCGGATACTT 636 57 1037 Antisense
ATACTTTCCAGATTATCCACCAACT 135 25 1056 Antisense
GCTGATCACATGGCAATTCTTAAAC 93 295 1192 Antisense
Sequence Source Affymetrix Proprietary Database