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[193221_s_at] inositol-1,4,5-triphosphate 5-phosphatase

Description C16C2.3 /REP_DB=WormBase Gene ID /WP=CE17405 /TR=O17590 /GB=CAB02743.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=inositol-1,4,5-triphosphate 5-phosphatase
Cluster 6grp_highest_10_10 > 27      6grp_high1_10_10 > 72      4grp_highest_8_8 > 50      4grp_high_8_8 > 33      6grp_highest_nonorm > 63      6grp_total > 72      4grp_total > 47      6grp_highest_sub > 03_04      6grp_cgc > 75      6grp_high1_sub > 04      6grp_cgc_sub > 03_04      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 198
1 2 3 4 range
A 473.6
(3)
P 		451
(1.9)
P 		345.2
(-3)
P 		384.8
(-1.1)
P 		128
B 504.3
(3)
P 		443.1
(-1.4)
P 		470.1
(0.5)
P 		420.6
(-3)
P 		84
C 543
(3)
P 		435.8
(-3)
P 		483.5
(-0.3)
P 		489.9
(0)
P 		107
avr 507
(3) 		443.3
(-2.1) 		432.9
(-2.9) 		431.8
(-3) 		75

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 389
1 2 3 4 5 6 range
A 524.3
(-3)
P 		611.2
(0.4)
P 		632.3
(1.2)
P 		676.9
(3)
P 		655.3
(2.2)
P 		541.3
(-2.3)
P 		153
B 531.8
(-3)
P 		665.6
(1.9)
P 		695
(3)
P 		654.8
(1.5)
P 		606.8
(-0.2)
P 		617.5
(0.2)
P 		163
C 509.7
(-3)
P 		681.5
(-0.4)
P 		753.7
(0.8)
P 		899.1
(3)
P 		614.4
(-1.4)
P 		638.5
(-1)
P 		389
avr 521.9
(-3) 		652.8
(0.5) 		693.7
(1.6) 		743.6
(3) 		625.5
(-0.2) 		599.1
(-0.9) 		222
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 123
1 2 3 4 range
A 172.4
(3)
P 		97.9
(-0.9)
P 		90.2
(-1.2)
P 		56.3
(-3)
P 		116
B 160.8
(3)
P 		109.4
(-1.3)
P 		108.9
(-1.4)
P 		89.6
(-3)
P 		71
C 179.7
(3)
P 		125.3
(-0.4)
P 		168.5
(2.3)
P 		82.6
(-3)
P 		97
avr 171
(3) 		110.9
(-0.8) 		122.5
(-0.1) 		76.2
(-3) 		95

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 150
1 2 3 4 5 6 range
A 96.7
(-3)
P 		217.4
(3)
P 		137.7
(-1)
P 		171.7
(0.7)
P 		197.7
(2)
P 		131.8
(-1.3)
P 		121
B 185.1
(-1.7)
P 		221.5
(1.1)
P 		168.8
(-3)
P 		173.4
(-2.6)
P 		246.5
(3)
P 		230.3
(1.7)
P 		78
C 188.9
(-1.5)
P 		207.9
(1.9)
P 		191.8
(-1)
P 		180.8
(-3)
P 		198.8
(0.3)
P 		213.8
(3)
P 		33
avr 156.9
(-3) 		215.6
(3) 		166.1
(-2.1) 		175.3
(-1.1) 		214.3
(2.9) 		192
(0.6) 		59
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193221_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.786
Sequence Type Exemplar sequence
Representative Public ID C16C2.3 NCBI
Target Description C16C2.3 /REP_DB=WormBase Gene ID /WP=CE17405 /TR=O17590 /GB=CAB02743.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=inositol-1,4,5-triphosphate 5-phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060183(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060183 NCBI Caenorhabditis elegans OCRL (Lowe's oculocerebrorenal syndrome protein) homolog family member (ocrl-1) (ocrl-1) mRNA, complete cds. 11/11 None
SNAP00000032648 ENSEMBL cdna:SNAP chromosome:CEL140:I:9723754:9728966:-1 11/11 None
GENEFINDER00000032653 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9723754:9728966:-1 11/11 None
C16C2.3 ENSEMBL cdna:known chromosome:CEL140:I:9723457:9736229:-1 gene:C16C2.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9723684-9736160(-) 100.0 100.0
Public Domain and Genome References
Gene Title inositol-1,4,5-triphosphate 5-phosphatase
Gene Symbol ocrl-1
Ensembl C16C2.3
Entrez Gene 172822 Entrez gene
SwissProt O17590 EMBL-EBI
WormBase CE17405 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:19243_AT endonuclease/exonuclease/phosphatase family protein at
ATH1-121501:263596_AT endonuclease/exonuclease/phosphatase family protein at
DROSOPHILA_2:1638197_AT dm
DROSGENOME1:141448_AT dm
CHICKEN:GGA.12952.1.S1_AT inositol polyphosphate-5-phosphatase, 75kDa gga
CHICKEN:GGAAFFX.1026.1.S1_AT inositol polyphosphate-5-phosphatase, 75kDa gga
HG-U133A_2:213643_S_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HG-U133_PLUS_2:213643_S_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HG-U133A:213643_S_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HU35KSUBC:RC_AA126095_S_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HU35KSUBD:RC_H23446_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HUGENEFL:M74161_AT inositol polyphosphate-5-phosphatase, 75kDa hs
U133_X3P:HS2.407126.1.S1_3P_X_AT inositol polyphosphate-5-phosphatase, 75kDa hs
U133_X3P:HS.182577.1.S1_3P_A_AT inositol polyphosphate-5-phosphatase, 75kDa hs
U133_X3P:HS.182577.0.S1_3P_X_AT inositol polyphosphate-5-phosphatase, 75kDa hs
U133_X3P:HS.182577.0.S1_3P_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HG-U133_PLUS_2:1563565_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HG-U133A_2:213804_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HG-U133_PLUS_2:213804_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HG-U133A:213804_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HG-U95AV2:33290_AT inositol polyphosphate-5-phosphatase, 75kDa hs
HU35KSUBC:RC_N26401_AT Inositol polyphosphate-5-phosphatase, 75kDa hs
MU11KSUBB:MSA.36373.0_F_AT inositol polyphosphate-5-phosphatase B mm
MU11KSUBB:MSA.17055.0_F_AT inositol polyphosphate-5-phosphatase B mm
MG-U74AV2:94399_AT inositol polyphosphate-5-phosphatase B mm
MG-U74AV2:94398_S_AT inositol polyphosphate-5-phosphatase B mm
MOE430A:1451330_A_AT inositol polyphosphate-5-phosphatase B mm
MOUSE430A_2:1451330_A_AT inositol polyphosphate-5-phosphatase B mm
MOUSE430_2:1451330_A_AT inositol polyphosphate-5-phosphatase B mm
MU19KSUBB:TC29132_AT Inositol polyphosphate-5-phosphatase B, mRNA (cDNA clone MGC:25218 IMAGE:4457437) mm
RG-U34C:RC_AI172296_AT inositol polyphosphate-5-phosphatase B (predicted) rn
RAE230A:1388502_AT Inositol polyphosphate-5-phosphatase B (predicted) rn
RAT230_2:1388502_AT Inositol polyphosphate-5-phosphatase B (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4437 inositol or phosphatidylinositol phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02743 Hypothetical protein C16C2.3 [Caenorhabditis elegans] ref|NP_492584.1| OCRL (Lowe's oculocerebrorenal syndrome protein) homolog family member (ocrl-1) [Caenorhabditis elegans] 0.0
blast CAE60242 Hypothetical protein CBG03815 [Caenorhabditis briggsae] 0.0
blast XP_417756 PREDICTED: similar to Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (Phosphoinositide 5-phosphatase) (5PTase) [Gallus gallus] 2.0E-86
Protein Domains
Database ID Description E-Value
scop a.4.5.Plant O-methyltransferase, N-terminal domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; Plant O-methyltransferase, N-terminal domain 8.60000038146973
Pfam IPR005135 EMBL-EBI Endonuclease/exonuclease/phosphatase 3.9E-41
Pfam IPR005135 EMBL-EBI Endonuclease/exonuclease/phosphatase 3.9E-41
Sequence
Target Sequence 
>C. ELEGANS:193221_S_AT
aattcactttctgacaactgtcctccaaatgttcctcgagtaatttatcggcttgtgatg
gctcttcgaacacgtggagcagttcagttaaatattgaagaagaacaggacaatgaggtc
tttaatagaatcagatctgcacttgaatctggacagcccgacgatttgagccaacttgca
tcttcttatatgttgtacagcgcattaatacgattgctcgactctctggatgagcctata
attttggaaggaatgttcaaaatcattcataaagaaatgataaaatatcgaaccgatgcc
agacaattatggaccgttgttcgatcaagtcttcccaaacagaatcaagcagttctcgaa
ttgatatgtctgatgctccgagagttctttagtcagaaatacgaattgaaagatcaatta
tcactttgggcaactgtattattccggcacg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATTCACTTTCTGACAACTGTCCTC 90 177 1738 Antisense
TGACAACTGTCCTCCAAATGTTCCT 663 571 1749 Antisense
GTTCCTCGAGTAATTTATCGGCTTG 513 441 1768 Antisense
ATCGGCTTGTGATGGCTCTTCGAAC 350 35 1784 Antisense
TGCACTTGAATCTGGACAGCCCGAC 579 577 1875 Antisense
GCCAACTTGCATCTTCTTATATGTT 240 279 1907 Antisense
AATACGATTGCTCGACTCTCTGGAT 23 173 1944 Antisense
GACCGTTGTTCGATCAAGTCTTCCC 641 379 2049 Antisense
GATATGTCTGATGCTCCGAGAGTTC 673 425 2100 Antisense
GATCAATTATCACTTTGGGCAACTG 173 423 2149 Antisense
TGGGCAACTGTATTATTCCGGCACG 328 555 2164 Antisense
Sequence Source Affymetrix Proprietary Database