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[193219_s_at] Peptidyl-prolyl cis-trans isomerases

Description Y75B12B.2 /REP_DB=WormBase Gene ID /WP=CE20371 /TR=SW:P52015 /GB=CAA21760.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Peptidyl-prolyl cis-trans isomerases
Cluster 6grp_highest_10_10 > 46      6grp_high1_10_10 > 54      4grp_highest_8_8 > 12      4grp_high_8_8 > 38      6grp_highest_nonorm > 06      6grp_total > 54      4grp_total > 33      6grp_cgc > 55      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 7706
1 2 3 4 range
A 9744.4
(-3)
P 		14446.3
(3)
P 		13138.5
(1.3)
P 		13467.7
(1.8)
P 		4702
B 6740.1
(-3)
P 		11957.9
(2)
P 		13035.8
(3)
P 		12490.4
(2.5)
P 		6296
C 8587.3
(-3)
P 		11798.3
(1.6)
P 		12792.2
(3)
P 		12343.6
(2.4)
P 		4205
avr 8357.3
(-3) 		12734.2
(2.7) 		12988.8
(3) 		12767.2
(2.7) 		4632

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2775
1 2 3 4 5 6 range
A 8492.6
(-2.2)
P 		9007.6
(-1.1)
P 		10889.1
(3)
P 		8798.4
(-1.5)
P 		8119.2
(-3)
P 		9624.5
(0.3)
P 		2770
B 8808.1
(-2)
P 		8735.1
(-2.3)
P 		9849.9
(2.1)
P 		8560.9
(-3)
P 		9615.3
(1.1)
P 		10086.8
(3)
P 		1526
C 8114.4
(-3)
P 		9913
(3)
P 		9813.4
(2.7)
P 		8402.5
(-2)
P 		9139.5
(0.4)
P 		8348.7
(-2.2)
P 		1799
avr 8471.7
(-3) 		9218.6
(-0.4) 		10184.1
(3) 		8587.3
(-2.6) 		8958
(-1.3) 		9353.3
(0.1) 		1712
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2487
1 2 3 4 range
A 3547.9
(3)
P 		3135.9
(1.4)
P 		3434.6
(2.6)
P 		1971.4
(-3)
P 		1577
B 2149.4
(-3)
P 		2953.3
(2.5)
P 		3020.7
(3)
P 		2661.7
(0.5)
P 		871
C 2842.6
(-1.1)
P 		3392.1
(0.3)
P 		4458.5
(3)
P 		2081.3
(-3)
P 		2377
avr 2846.6
(-0.4) 		3160.4
(1) 		3637.9
(3) 		2238.1
(-3) 		1400

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2341
1 2 3 4 5 6 range
A 1565.6
(-3)
P 		3203.5
(3)
P 		2371.4
(-0)
P 		2231.5
(-0.6)
P 		2450
(0.2)
P 		2343.3
(-0.2)
P 		1638
B 3064.8
(-0.1)
P 		2907.5
(-0.7)
P 		2391.8
(-2.5)
P 		2267.5
(-3)
P 		3906.6
(3)
P 		3761.3
(2.5)
P 		1639
C 3007.6
(2.9)
P 		3024.8
(3)
P 		2497.7
(0.6)
P 		1689.7
(-3)
P 		2957.4
(2.7)
P 		2794.8
(2)
P 		1335
avr 2546
(-0.2) 		3045.3
(2.7) 		2420.3
(-0.9) 		2062.9
(-3) 		3104.7
(3) 		2966.5
(2.2) 		1042
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193219_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13712
Sequence Type Exemplar sequence
Representative Public ID Y75B12B.2 NCBI
Target Description Y75B12B.2 /REP_DB=WormBase Gene ID /WP=CE20371 /TR=SW:P52015 /GB=CAA21760.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Peptidyl-prolyl cis-trans isomerases
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074348(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074348 NCBI Caenorhabditis elegans CYclophyliN family member (cyn-7) (cyn-7) mRNA, complete cds. 11/11 None
SNAP00000027056 ENSEMBL cdna:SNAP chromosome:CEL140:V:15189269:15189946:-1 11/11 None
GENEFINDER00000027069 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15189269:15189946:-1 11/11 None
Y75B12B.2.4 ENSEMBL cdna:known chromosome:CEL140:V:15189166:15189970:-1 gene:Y75B12B.2 11/11 None
Y75B12B.2.2 ENSEMBL cdna:known chromosome:CEL140:V:15189166:15189964:-1 gene:Y75B12B.2 11/11 None
Y75B12B.2.1 ENSEMBL cdna:known chromosome:CEL140:V:15189171:15189970:-1 gene:Y75B12B.2 11/11 None
Y75B12B.2.3 ENSEMBL cdna:known chromosome:CEL140:V:15189171:15190066:-1 gene:Y75B12B.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15189268-15189946(-) 100.0 100.0
Public Domain and Genome References
Gene Title Peptidyl-prolyl cis-trans isomerases
Gene Symbol cyn-7
Ensembl Y75B12B.2
Entrez Gene 180027 Entrez gene
SwissProt P52015 EMBL-EBI
WormBase CE20371 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:252973_S_AT peptidyl-prolyl cis-trans isomerase / cyclophilin / rotamase / cyclosporin A-binding protein (ROC1) at
CANINE_2:CFA.16705.1.S1_AT similar to Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (PPIase) (Rotamase) (Cyclophilin F) cfa
CANINE_2:CFAAFFX.24044.1.S1_AT similar to Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (PPIase) (Rotamase) (Cyclophilin F) cfa
DROSOPHILA_2:1638036_AT Cyclophilin 1 dm
DROSGENOME1:141478_AT Cyclophilin 1 dm
CHICKEN:GGA.1727.1.S1_S_AT peptidylprolyl isomerase F (cyclophilin F) gga
CHICKEN:GGAAFFX.11497.1.S1_AT peptidylprolyl isomerase F (cyclophilin F) gga
HG-U133A:201489_AT peptidylprolyl isomerase F (cyclophilin F) hs
HG-U133A_2:201489_AT peptidylprolyl isomerase F (cyclophilin F) hs
HG-U133_PLUS_2:201489_AT peptidylprolyl isomerase F (cyclophilin F) hs
HG-FOCUS:201489_AT peptidylprolyl isomerase F (cyclophilin F) hs
HG-U133A:201490_S_AT peptidylprolyl isomerase F (cyclophilin F) hs
HG-U133_PLUS_2:201490_S_AT peptidylprolyl isomerase F (cyclophilin F) hs
HG-U133A_2:201490_S_AT peptidylprolyl isomerase F (cyclophilin F) hs
HU35KSUBD:RC_AA404286_AT peptidylprolyl isomerase F (cyclophilin F) hs
HUGENEFL:M80254_AT peptidylprolyl isomerase F (cyclophilin F) hs
U133_X3P:G5031986_3P_A_AT peptidylprolyl isomerase F (cyclophilin F) hs
U133_X3P:G13477126_3P_AT peptidylprolyl isomerase F (cyclophilin F) hs
HG-U95AV2:40840_AT peptidylprolyl isomerase F (cyclophilin F) hs
MG-U74AV2:99159_AT peptidylprolyl isomerase F (cyclophilin F) mm
MG-U74CV2:171499_AT peptidylprolyl isomerase F (cyclophilin F) mm
MOE430A:1438955_X_AT peptidylprolyl isomerase F (cyclophilin F) mm
MOUSE430A_2:1438955_X_AT peptidylprolyl isomerase F (cyclophilin F) mm
MOUSE430_2:1438955_X_AT peptidylprolyl isomerase F (cyclophilin F) mm
MOE430A:1416940_AT peptidylprolyl isomerase F (cyclophilin F) mm
MOUSE430A_2:1416940_AT peptidylprolyl isomerase F (cyclophilin F) mm
MOUSE430_2:1416940_AT peptidylprolyl isomerase F (cyclophilin F) mm
MU19KSUBA:TC23916_AT Peptidylprolyl isomerase F (cyclophilin F) (Ppif), mRNA mm
RT-U34:U68544_AT peptidylprolyl isomerase F (cyclophilin F) rn
RG-U34A:U68544_AT peptidylprolyl isomerase F (cyclophilin F) rn
RAE230A:1370319_AT peptidylprolyl isomerase F (cyclophilin F) rn
RAT230_2:1370319_AT peptidylprolyl isomerase F (cyclophilin F) rn
YEAST_2:1772130_AT Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA21760 Hypothetical protein Y75B12B.2 [Caenorhabditis elegans] ref|NP_506749.1| CYclophyliN family member (cyn-7) [Caenorhabditis elegans] sp|P52015|CYP7_CAEEL Peptidyl-prolyl cis-trans isomerase 7 (PPIase) (Rotamase) (Cyclophilin-7) 2.0E-88
blast AAC47125 cyclophilin 8.0E-88
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 3.2E-117
Sequence
Target Sequence 
>C. ELEGANS:193219_S_AT
gctctacaacgatattgttccaaaaaccgctgagaacttccgtgctctttgcactggtga
gaagggagtcggaaagtccggaaagccactccacttcaagggatccaagttccatcgtat
catcccagaattcatgatccaggg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTCTACAACGATATTGTTCCAAAA 275 301 81 Antisense
ACGATATTGTTCCAAAAACCGCTGA 665 91 89 Antisense
AAAAACCGCTGAGAACTTCCGTGCT 696 127 102 Antisense
TGAGAACTTCCGTGCTCTTTGCACT 169 569 111 Antisense
CTTCCGTGCTCTTTGCACTGGTGAG 4 221 117 Antisense
GTGCTCTTTGCACTGGTGAGAAGGG 280 479 122 Antisense
GTGAGAAGGGAGTCGGAAAGTCCGG 239 389 137 Antisense
CAAGGGATCCAAGTTCCATCGTATC 361 183 177 Antisense
GGATCCAAGTTCCATCGTATCATCC 101 513 181 Antisense
CATCGTATCATCCCAGAATTCATGA 531 211 193 Antisense
TCATCCCAGAATTCATGATCCAGGG 87 623 200 Antisense
Sequence Source Affymetrix Proprietary Database