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[193216_at] Inhibitor of Apoptosis domain.

Description C50B8.2 /REP_DB=WormBase Gene ID /WP=CE08882 /GEN=bir-2 /TR=Q18727 /GB=CAB01130.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Inhibitor of Apoptosis domain.
Cluster 6grp_total > 98      4grp_total > 0      6grp_cgc > 69      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 100
1 2 3 4 range
A 61.9
(-1.9)
A 		43.1
(-3)
A 		110.9
(1.1)
P 		143.2
(3)
P 		100
B 65.7
(-3)
A 		69.2
(-2.7)
M 		90.2
(-1.1)
P 		143.1
(3)
P 		77
C 70.6
(-3)
A 		73.2
(-2.8)
A 		110.3
(0.3)
P 		143.1
(3)
P 		73
avr 66.1
(-2.7) 		61.8
(-3) 		103.8
(0.1) 		143.1
(3) 		81

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 664
1 2 3 4 5 6 range
A 73.3
(-2.7)
A 		42
(-3)
A 		68.3
(-2.7)
P 		125.6
(-2.2)
P 		524.9
(1.6)
P 		670.6
(3)
P 		629
B 41.9
(-3)
A 		58.1
(-2.9)
M 		69.7
(-2.7)
P 		189.9
(-1.7)
P 		463.2
(0.8)
P 		705.7
(3)
P 		664
C 45.6
(-3)
A 		63.5
(-2.8)
A 		53.2
(-2.9)
A 		143.7
(-2)
P 		439.1
(0.8)
P 		664.5
(3)
P 		619
avr 53.6
(-3) 		54.5
(-3) 		63.7
(-2.9) 		153.1
(-2) 		475.7
(1) 		680.3
(3) 		627
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 29
1 2 3 4 range
A 22.5
(1)
A 		9.4
(-3)
A 		29
(3)
P 		21
(0.6)
P 		20
B 21
(-1.3)
A 		17.1
(-3)
M 		20.9
(-1.3)
P 		30.5
(3)
P 		13
C 23.4
(-2.2)
A 		21
(-3)
A 		38.4
(3)
P 		24.1
(-1.9)
P 		17
avr 22.3
(-0.1) 		15.8
(-3) 		29.4
(3) 		25.2
(1.1) 		14

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 250
1 2 3 4 5 6 range
A 13.5
(-3)
A 		14.9
(-2.9)
A 		14.9
(-2.9)
P 		31.8
(-2.3)
P 		158.4
(2.8)
P 		163.3
(3)
P 		150
B 14.6
(-3)
A 		19.3
(-2.9)
M 		16.9
(-2.9)
P 		50.3
(-2.1)
P 		188.2
(1.2)
P 		263.2
(3)
P 		249
C 16.9
(-2.9)
A 		19.4
(-2.8)
A 		13.5
(-3)
A 		28.9
(-2.6)
P 		142.1
(0.7)
P 		222.5
(3)
P 		209
avr 15
(-3) 		17.9
(-2.9) 		15.1
(-3) 		37
(-2.3) 		162.9
(1.4) 		216.3
(3) 		201
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193216_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13005
Sequence Type Exemplar sequence
Representative Public ID C50B8.2 NCBI
Target Description C50B8.2 /REP_DB=WormBase Gene ID /WP=CE08882 /GEN=bir-2 /TR=Q18727 /GB=CAB01130.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Inhibitor of Apoptosis domain.
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073961(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073961 NCBI Caenorhabditis elegans BIR (baculovirus inhibitory repeat) family member (bir-2) (bir-2) mRNA, complete cds. 11/11 None
SNAP00000010252 ENSEMBL cdna:SNAP chromosome:CEL140:V:13571445:13572508:1 11/11 None
GENEFINDER00000010258 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:13571445:13572508:1 11/11 None
C50B8.2 ENSEMBL cdna:known chromosome:CEL140:V:13571442:13572614:1 gene:C50B8.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:13571444-13572508(+) 100.0 100.0
Public Domain and Genome References
Gene Title Inhibitor of Apoptosis domain.
Gene Symbol bir-2
Ensembl C50B8.2
Entrez Gene 179841 Entrez gene
SwissProt Q18727 EMBL-EBI
WormBase CE08882 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6916 anti-apoptosis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01130 Hypothetical protein C50B8.2 [Caenorhabditis elegans] ref|NP_506362.1| BIR (baculovirus inhibitory repeat) family member (bir-2) [Caenorhabditis elegans] gb|AAD00182.1| inhibitor of apoptosis homolog [Caenorhabditis elegans] 1.0E-166
blast CAB01130 Hypothetical protein C50B8.2 [Caenorhabditis elegans] ref|NP_506362.1| BIR (baculovirus inhibitory repeat) family member (bir-2) [Caenorhabditis elegans] gb|AAD00182.1| inhibitor of apoptosis homolog [Caenorhabditis elegans] 1.0E-164
blast CAE66290 Hypothetical protein CBG11537 [Caenorhabditis briggsae] 5.0E-68
blast CAE66290 Hypothetical protein CBG11537 [Caenorhabditis briggsae] 1.0E-65
blast CAA98553 Hypothetical protein T27F2.3 [Caenorhabditis elegans] ref|NP_505949.1| BIR (baculovirus inhibitory repeat) family member (bir-1) [Caenorhabditis elegans] gb|AAB94330.1| inhibitor of apoptosis homolog [Caenorhabditis elegans] 3.0E-18
Protein Domains
Database ID Description E-Value
Pfam IPR001370 EMBL-EBI Baculovirus inhibitor of apoptosis protein repeat (BIR) 1.7E-28
Pfam IPR001370 EMBL-EBI Baculovirus inhibitor of apoptosis protein repeat (BIR) 1.0E-28
Pfam IPR001370 EMBL-EBI Baculovirus inhibitor of apoptosis protein repeat (BIR) 1.1E-22
Sequence
Target Sequence 
>C. ELEGANS:193216_AT
aagtgaactttctttccgaatcatatccaatcttgcgatacgacacgcaacagtgagact
ttacgaagagctacttggaatcgtagcgacattggaaaatggagacattgctaatgaaaa
cccgattacccgcgctgacgccaccaggaaattgatttcattccgatcttctagcaagct
tctcacttttgatcatcgacttgccacattccaaaatttcattttcgacaaaaaaaggaa
tgtaaaatgcacttcaaagaagctcgccaaagctggatggttttctattgccaacaaaaa
agataaaacttctgcaaaatgtccattctgccttgttgagctggactttgacgaatcaga
tgatccgtgggaagagcatcagaagttcagtgcatcctgcgatttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGTGAACTTTCTTTCCGAATCATA 233 159 324 Antisense
TTCCGAATCATATCCAATCTTGCGA 51 699 337 Antisense
GCTAATGAAAACCCGATTACCCGCG 437 299 433 Antisense
ATTGATTTCATTCCGATCTTCTAGC 538 5 474 Antisense
GATCTTCTAGCAAGCTTCTCACTTT 618 419 488 Antisense
TCTCACTTTTGATCATCGACTTGCC 601 613 504 Antisense
TCGACTTGCCACATTCCAAAATTTC 413 601 519 Antisense
GCTGGATGGTTTTCTATTGCCAACA 48 295 595 Antisense
AAAATGTCCATTCTGCCTTGTTGAG 421 133 639 Antisense
CATTCTGCCTTGTTGAGCTGGACTT 147 217 647 Antisense
GAAGTTCAGTGCATCCTGCGATTTT 468 337 705 Antisense
Sequence Source Affymetrix Proprietary Database