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[193189_at] G-protein coupled receptor (family 1)

Description C25G6.5 /REP_DB=WormBase Gene ID /WP=CE04086 /TR=SW:Q18179 /GB=AAA82357.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor (family 1)
Cluster 6grp_total > 39      4grp_total > 13      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 112
1 2 3 4 range
A 94.5
(0.1)
P 		80.2
(-0.9)
A 		51.3
(-3)
A 		134.7
(3)
P 		83
B 81.4
(1)
P 		27.9
(-2.9)
A 		26.5
(-3)
A 		109.7
(3)
P 		83
C 75.9
(0.3)
A 		36.2
(-2.2)
A 		22.7
(-3)
A 		119.8
(3)
M 		97
avr 83.9
(0.4) 		48.1
(-2) 		33.5
(-3) 		121.4
(3) 		88

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 72
1 2 3 4 5 6 range
A 70.4
(2.6)
A 		38.4
(-0)
A 		3
(-3)
A 		33.3
(-0.5)
A 		74.9
(3)
A 		23.5
(-1.3)
A 		72
B 67.9
(3)
M 		49.6
(1.1)
A 		10.7
(-3)
A 		39.2
(-0)
A 		16.8
(-2.4)
A 		57.8
(1.9)
P 		57
C 70.3
(3)
A 		31.8
(-0.5)
A 		3.6
(-3)
A 		9
(-2.5)
A 		43.5
(0.6)
A 		67.9
(2.8)
A 		67
avr 69.5
(3) 		39.9
(0.2) 		5.8
(-3) 		27.2
(-1) 		45.1
(0.7) 		49.7
(1.1) 		64
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 28
1 2 3 4 range
A 34.4
(3)
P 		17.4
(-1.9)
A 		13.4
(-3)
A 		19.7
(-1.2)
P 		21
B 26
(3)
P 		6.9
(-2.8)
A 		6.1
(-3)
A 		23.4
(2.2)
P 		20
C 25.1
(3)
A 		10.4
(-2.1)
A 		7.9
(-3)
A 		20.2
(1.3)
M 		17
avr 28.5
(3) 		11.6
(-2.2) 		9.1
(-3) 		21.1
(0.7) 		19

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 25
1 2 3 4 5 6 range
A 13
(0.4)
A 		13.6
(0.5)
A 		0.7
(-3)
A 		8.5
(-0.9)
A 		22.6
(3)
A 		5.7
(-1.6)
A 		22
B 23.6
(3)
M 		16.5
(1)
A 		2.6
(-3)
A 		10.4
(-0.8)
A 		6.8
(-1.8)
A 		21.6
(2.4)
P 		21
C 26.1
(3)
A 		9.7
(-0.9)
A 		0.9
(-3)
A 		1.8
(-2.8)
A 		14.1
(0.1)
A 		22.7
(2.2)
A 		25
avr 20.9
(3) 		13.3
(0.7) 		1.4
(-3) 		6.9
(-1.3) 		14.5
(1) 		16.7
(1.7) 		20
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193189_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18142
Sequence Type Exemplar sequence
Representative Public ID C25G6.5 NCBI
Target Description C25G6.5 /REP_DB=WormBase Gene ID /WP=CE04086 /TR=SW:Q18179 /GB=AAA82357.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor (family 1)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075833(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075833 NCBI Caenorhabditis elegans C25G6.5 (C25G6.5) mRNA, complete cds. 11/11 None
SNAP00000031325 ENSEMBL cdna:SNAP chromosome:CEL140:X:1251993:1255135:-1 9/11 None
GENEFINDER00000031331 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:1251993:1255610:-1 9/11 None
C25G6.5 ENSEMBL cdna:known chromosome:CEL140:X:1251020:1255610:-1 gene:C25G6.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:1251019-1255610(-) 95.76 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor (family 1)
Ensembl C25G6.5
Entrez Gene 182921 Entrez gene
SwissProt Q18179 EMBL-EBI
WormBase CE04086 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1582611_AT neuropeptide Y receptor Y5 cfa
CANINE_2:CFA.3575.1.S1_S_AT neuropeptide Y receptor Y5 cfa
CHICKEN:GGA.11107.1.S1_AT neuropeptide Y receptor Y5 gga
CHICKEN:GGAAFFX.22943.1.S1_AT neuropeptide Y receptor Y5 gga
HUGENEFL:U94320_AT neuropeptide Y receptor Y5 hs
HG-U133A:207400_AT neuropeptide Y receptor Y5 hs
HG-U133_PLUS_2:207400_AT neuropeptide Y receptor Y5 hs
HG-FOCUS:207400_AT neuropeptide Y receptor Y5 hs
HG-U133A_2:207400_AT neuropeptide Y receptor Y5 hs
U133_X3P:G5453795_3P_AT neuropeptide Y receptor Y5 hs
HG-U95AV2:33100_AT neuropeptide Y receptor Y5 hs
MG-U74AV2:94115_AT neuropeptide Y receptor Y5 mm
MOUSE430_2:1419008_AT neuropeptide Y receptor Y5 mm
MOE430A:1419008_AT neuropeptide Y receptor Y5 mm
MOUSE430A_2:1419008_AT neuropeptide Y receptor Y5 mm
MOUSE430_2:1449312_AT neuropeptide Y receptor Y5 mm
MOE430A:1449312_AT neuropeptide Y receptor Y5 mm
MOUSE430A_2:1449312_AT neuropeptide Y receptor Y5 mm
RN-U34:U66274_AT neuropeptide Y receptor Y5 rn
RG-U34A:U66274_AT neuropeptide Y receptor Y5 rn
RAE230A:1369246_A_AT neuropeptide Y receptor Y5 rn
RAT230_2:1369246_A_AT neuropeptide Y receptor Y5 rn
RAE230A:1387497_AT neuropeptide Y receptor Y5 rn
RAT230_2:1387497_AT neuropeptide Y receptor Y5 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
4983 neuropeptide Y receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA82357 Hypothetical protein C25G6.5 [Caenorhabditis elegans] ref|NP_508234.1| C25G6.5 [Caenorhabditis elegans] sp|Q18179|YXX5_CAEEL Putative neuropeptide Y receptor (NPY-R) 0.0
blast CAE63566 Hypothetical protein CBG08053 [Caenorhabditis briggsae] 0.0
blast AAA82357 Hypothetical protein C25G6.5 [Caenorhabditis elegans] ref|NP_508234.1| C25G6.5 [Caenorhabditis elegans] sp|Q18179|YXX5_CAEEL Putative neuropeptide Y receptor (NPY-R) 1.0E-145
blast CAE63566 Hypothetical protein CBG08053 [Caenorhabditis briggsae] 1.0E-135
blast CAE61776 Hypothetical protein CBG05736 [Caenorhabditis briggsae] 2.0E-43
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 1.2E-60
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 6.9E-42
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508234.1 7 42-64,76-98,118-140,153-175,210-232,270-292,307-329
C25G6.5 7 42-64,76-98,118-140,153-175,210-232,270-292,307-329
SNAP00000031325 5 20-39,51-73,108-130,168-190,205-227
GENEFINDER00000031331 7 42-64,76-98,118-140,153-175,210-232,270-292,307-329
Sequence
Target Sequence 
>C. ELEGANS:193189_AT
cctccttcttgtatgcgttgtagctgtattcgccgtcgcctggctgccactcaacgtttt
tcatatcttcaacacattcgagctggtcaacagtttttccgttacaacgttcagcatctg
tcactgcttggcaatgtgctcggcgtgcttgaatccgctgatctatgcatttttcaatca
taacttccggatcgaatttatgcatcttttcgatagagttgggttgagatcccttcgagt
cgtgatatttggagagcaagagtcgctcaagaaaagtatgcgcactgaattcagaagccg
tggaggctgtaagacggtaactactgcagagccagcaaccttccagagaatgaatgaaag
tatgattctgagtgcgatggagcaagatgagcagctatcgagtgggggcaaactttttgt
tctaaaaaaatatattttgaagatgttccaaaaaggtggtcacaagcaatcgactccagc
ctctccccggctaggatttggttat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCTCCTTCTTGTATGCGTTGTAGCT 370 267 822 Antisense
GCCACTCAACGTTTTTCATATCTTC 205 279 867 Antisense
ATCTTCAACACATTCGAGCTGGTCA 556 31 886 Antisense
GCTGGTCAACAGTTTTTCCGTTACA 397 295 903 Antisense
CAACGTTCAGCATCTGTCACTGCTT 537 187 926 Antisense
GTCACTGCTTGGCAATGTGCTCGGC 603 465 941 Antisense
GAATCCGCTGATCTATGCATTTTTC 139 331 972 Antisense
GTTGGGTTGAGATCCCTTCGAGTCG 452 433 1039 Antisense
GTAACTACTGCAGAGCCAGCAACCT 36 463 1138 Antisense
TGGTCACAAGCAATCGACTCCAGCC 565 551 1278 Antisense
CTCTCCCCGGCTAGGATTTGGTTAT 23 221 1302 Antisense
Sequence Source Affymetrix Proprietary Database