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[193185_at] protein-tyrosine phosphatase

Description C05B10.1 /REP_DB=WormBase Gene ID /WP=CE07918 /GEN=lip-1 /TR=O44128 /GB=AAB88308.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 47      4grp_total > 03      6grp_cgc > 17      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 107
1 2 3 4 range
A 43.5
(-1.1)
A 		13.3
(-3)
A 		26.8
(-2.2)
A 		110.2
(3)
P 		97
B 44.1
(-2.4)
A 		36
(-3)
A 		35.5
(-3)
A 		120.7
(3)
P 		85
C 42.4
(-1)
A 		55.5
(0.1)
A 		16.5
(-3)
A 		93
(3)
P 		77
avr 43.3
(-1.8) 		34.9
(-2.4) 		26.3
(-3) 		108
(3) 		82

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 133
1 2 3 4 5 6 range
A 137.3
(3)
P 		64.3
(-0.3)
A 		96.3
(1.2)
P 		4.1
(-3)
A 		46.4
(-1.1)
A 		82.9
(0.5)
P 		133
B 122.3
(3)
P 		77.6
(-0)
P 		44.2
(-2.3)
A 		33.6
(-3)
A 		50.7
(-1.8)
P 		89.9
(0.8)
P 		89
C 34.6
(-2.3)
A 		98.6
(2.4)
P 		25.6
(-3)
A 		34.8
(-2.3)
A 		35.1
(-2.3)
A 		106.3
(3)
P 		81
avr 98.1
(3) 		80.2
(1.5) 		55.4
(-0.5) 		24.2
(-3) 		44.1
(-1.4) 		93
(2.6) 		74
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 15.8
(2.9)
A 		2.9
(-3)
A 		7
(-1.1)
A 		16.1
(3)
P 		13
B 14.1
(-1)
A 		8.9
(-2.8)
A 		8.2
(-3)
A 		25.7
(3)
P 		18
C 14
(1.8)
A 		16
(3)
A 		5.7
(-3)
A 		15.7
(2.8)
P 		10
avr 14.6
(0.7) 		9.3
(-1.9) 		7
(-3) 		19.2
(3) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 42
1 2 3 4 5 6 range
A 25.3
(3)
P 		22.9
(2.4)
A 		21
(1.9)
P 		1
(-3)
A 		14
(0.2)
A 		20.2
(1.7)
P 		24
B 42.6
(3)
P 		25.8
(0)
P 		10.7
(-2.7)
A 		8.9
(-3)
A 		20.6
(-0.9)
P 		33.5
(1.4)
P 		34
C 12.8
(-1.7)
A 		30.1
(1.9)
P 		6.5
(-3)
A 		7
(-2.9)
A 		11.4
(-2)
A 		35.6
(3)
P 		29
avr 26.9
(2.3) 		26.3
(2.1) 		12.7
(-1.2) 		5.6
(-3) 		15.3
(-0.6) 		29.8
(3) 		24
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193185_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9916
Sequence Type Exemplar sequence
Representative Public ID C05B10.1 NCBI
Target Description C05B10.1 /REP_DB=WormBase Gene ID /WP=CE07918 /GEN=lip-1 /TR=O44128 /GB=AAB88308.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068652(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068652 NCBI Caenorhabditis elegans Lateral-signal-Induced Phosphatase family member (lip-1) (lip-1) mRNA, complete cds. 11/11 None
SNAP00000023093 ENSEMBL cdna:SNAP chromosome:CEL140:IV:6842948:6845136:1 9/11 None
GENEFINDER00000023096 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:6842948:6845136:1 9/11 None
C05B10.1 ENSEMBL cdna:known chromosome:CEL140:IV:6842943:6844810:1 gene:C05B10.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:6842953-6844816(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Gene Symbol lip-1
Ensembl C05B10.1
Entrez Gene 191704 Entrez gene
SwissProt O44128 EMBL-EBI
WormBase CE31151 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.15543.1.S1_AT similar to dual specificity phosphatase 6 isoform b cfa
DROSGENOME1:149030_AT Mitogen-activated protein kinase phosphatase 3 dm
DROSOPHILA_2:1641361_A_AT Mitogen-activated protein kinase phosphatase 3 dm
DROSOPHILA_2:1637641_AT Mitogen-activated protein kinase phosphatase 3 dm
DROSGENOME1:141660_AT Mitogen-activated protein kinase phosphatase 3 dm
HU35KSUBA:X93921_AT dual specificity phosphatase 7 hs
HUGENEFL:X93921_AT dual specificity phosphatase 7 hs
U133_X3P:HS.296938.0.S1_3P_AT dual specificity phosphatase 7 hs
HG-U133A_2:214793_AT dual specificity phosphatase 7 hs
HG-U133_PLUS_2:214793_AT dual specificity phosphatase 7 hs
HG-U133A:214793_AT dual specificity phosphatase 7 hs
HG-U95AV2:39933_AT dual specificity phosphatase 7 hs
HU35KSUBB:RC_F08899_AT Dual specificity phosphatase 7 hs
U133_X3P:HS.3843.0.A1_3P_X_AT Dual specificity phosphatase 7 hs
U133_X3P:HS.3843.0.A1_3P_AT Dual specificity phosphatase 7 hs
HG-U133A_2:213848_AT Dual specificity phosphatase 7 hs
HG-U133_PLUS_2:213848_AT Dual specificity phosphatase 7 hs
HG-U133A:213848_AT Dual specificity phosphatase 7 hs
HG-U95AV2:39932_AT Dual specificity phosphatase 7 hs
MOUSE430_2:1427416_X_AT dual specificity phosphatase 7 mm
MOUSE430A_2:1427416_X_AT dual specificity phosphatase 7 mm
MOE430A:1427416_X_AT dual specificity phosphatase 7 mm
MU11KSUBB:MSA.16748.0_S_AT dual specificity phosphatase 7 mm
MG-U74BV2:108056_AT dual specificity phosphatase 7 mm
MOE430A:1452097_A_AT dual specificity phosphatase 7 mm
MOUSE430A_2:1452097_A_AT dual specificity phosphatase 7 mm
MOUSE430_2:1452097_A_AT dual specificity phosphatase 7 mm
MOE430A:1460393_A_AT dual specificity phosphatase 7 mm
MOUSE430A_2:1460393_A_AT dual specificity phosphatase 7 mm
MOUSE430_2:1460393_A_AT dual specificity phosphatase 7 mm
MU19KSUBA:TC15711_S_AT Dual specificity phosphatase 7 (Dusp7), mRNA mm
MU19KSUBC:TC36167_AT Dual specificity phosphatase 7 (Dusp7), mRNA mm
RT-U34:X94186_AT dual specificity phosphatase 7 rn
RG-U34A:X94186_AT dual specificity phosphatase 7 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8138 protein tyrosine/serine/threonine phosphatase activity inferred from electronic annotation QuickGO AmiGO
17017 MAP kinase phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB88308 Lateral-signal-induced phosphatase protein 1 [Caenorhabditis elegans] ref|NP_501053.2| Lateral-signal-Induced Phosphatase family member (lip-1) [Caenorhabditis elegans] 0.0
blast AAB88308 Lateral-signal-induced phosphatase protein 1 [Caenorhabditis elegans] ref|NP_501053.2| Lateral-signal-Induced Phosphatase family member (lip-1) [Caenorhabditis elegans] 1.0E-177
blast CAE61750 Hypothetical protein CBG05704 [Caenorhabditis briggsae] 1.0E-171
blast CAE61750 Hypothetical protein CBG05704 [Caenorhabditis briggsae] 1.0E-162
blast CAH65449 hypothetical protein [Gallus gallus] 1.0E-43
Protein Domains
Database ID Description E-Value
Pfam IPR000340 EMBL-EBI Dual specificity protein phosphatase 5.3E-55
Pfam IPR000340 EMBL-EBI Dual specificity protein phosphatase 5.3E-55
Sequence
Target Sequence 
>C. ELEGANS:193185_AT
gtatcttggaaacgcggagaccgctaaaaatcgagatgttcttaaaaaatattctatctc
acatgtaataaatgtcacatcaaatttgccaaacacgttcgaagaagacccaaatatgcg
atatttaagaatatcggccgatgataacgcttcacataatctaacaaaattcttccctga
agccatatccttcattgatgatgcgcgacgcaacgattcagcatgtcttgtgcattgtct
ggctggaatttccagaagcgttacaatatgtctggcgtatctcatgaagactgaaatgtg
tactcttgattctgcctacgaatgggttcaaaagagaaatgcaagcattgctccaaattt
tcattttatgggacaactcacagactacgagaagatgttgggattgaatagcaatcgagt
cggggttagtaggcaagctgtaaattttgatgttcactttttctgcattttta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTATCTTGGAAACGCGGAGACCGCT 44 453 576 Antisense
ATCGGCCGATGATAACGCTTCACAT 637 33 708 Antisense
ATTCTTCCCTGAAGCCATATCCTTC 534 11 744 Antisense
ATCCTTCATTGATGATGCGCGACGC 82 39 762 Antisense
GCGCGACGCAACGATTCAGCATGTC 105 287 778 Antisense
CATGTCTTGTGCATTGTCTGGCTGG 149 211 797 Antisense
GTTACAATATGTCTGGCGTATCTCA 175 445 835 Antisense
AATGTGTACTCTTGATTCTGCCTAC 663 163 870 Antisense
TTATGGGACAACTCACAGACTACGA 6 679 941 Antisense
GAGTCGGGGTTAGTAGGCAAGCTGT 653 399 992 Antisense
GATGTTCACTTTTTCTGCATTTTTA 489 409 1024 Antisense
Sequence Source Affymetrix Proprietary Database