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[193173_at]

Description ZK909.2B /REP_DB=WormBase Gene ID /WP=CE15475 /GEN=kin-1 /TR=O18311 /GB=CAB04169.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cAMP-dependant protein kinase
Cluster 6grp_high1_10_10 > 13      4grp_high_8_8 > 19      6grp_total > 21      4grp_total > 37      6grp_cgc > 44      6grp_high1_sub > De      6grp_cgc_sub > 02      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 154
1 2 3 4 range
A 140.1
(1.2)
P 		166
(3)
P 		123.9
(0)
P 		80.9
(-3)
A 		85
B 214.4
(3)
P 		176.5
(1.5)
P 		60.7
(-3)
A 		190.9
(2.1)
P 		154
C 190.1
(2)
P 		134.7
(-3)
P 		156.6
(-1)
P 		201.3
(3)
P 		67
avr 181.5
(3) 		159.1
(1) 		113.7
(-3) 		157.7
(0.9) 		68

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 181
1 2 3 4 5 6 range
A 236.4
(3)
P 		156.8
(0.3)
P 		182.3
(1.2)
P 		58.6
(-3)
A 		148.7
(0)
P 		71.3
(-2.6)
A 		178
B 148.1
(-2)
P 		240
(3)
P 		183.4
(-0.1)
P 		158.5
(-1.4)
P 		130.8
(-2.9)
P 		128.7
(-3)
P 		111
C 71.3
(-3)
A 		196.3
(3)
P 		150.7
(0.8)
P 		106.4
(-1.3)
A 		96.2
(-1.8)
P 		102
(-1.5)
P 		125
avr 151.9
(0.2) 		197.7
(3) 		172.1
(1.4) 		107.8
(-2.6) 		125.2
(-1.5) 		100.7
(-3) 		97
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 57
1 2 3 4 range
A 51
(3)
P 		36
(0.7)
P 		32.4
(0.2)
P 		11.8
(-3)
A 		39
B 68.4
(3)
P 		43.6
(0.3)
P 		14.1
(-3)
A 		40.7
(-0.1)
P 		54
C 62.9
(3)
P 		38.7
(-2)
P 		54.6
(1.3)
P 		33.9
(-3)
P 		29
avr 60.8
(3) 		39.4
(-1) 		33.7
(-2.1) 		28.8
(-3) 		32

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 65
1 2 3 4 5 6 range
A 43.6
(1.2)
P 		55.8
(3)
P 		39.7
(0.6)
P 		14.9
(-3)
A 		44.9
(1.4)
P 		17.4
(-2.6)
A 		41
B 51.5
(-1.5)
P 		79.9
(3)
P 		44.5
(-2.6)
P 		42
(-3)
P 		53.1
(-1.2)
P 		48
(-2.1)
P 		38
C 26.4
(-2.2)
A 		59.9
(3)
P 		38.4
(-0.4)
P 		21.4
(-3)
A 		31.1
(-1.5)
P 		34.1
(-1)
P 		39
avr 40.5
(-0.8) 		65.2
(3) 		40.9
(-0.7) 		26.1
(-3) 		43
(-0.4) 		33.2
(-1.9) 		39
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193173_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2488
Sequence Type Exemplar sequence
Representative Public ID ZK909.2B NCBI
Target Description ZK909.2B /REP_DB=WormBase Gene ID /WP=CE15475 /GEN=kin-1 /TR=O18311 /GB=CAB04169.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cAMP-dependant protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_170959(11), NM_170961(11), NM_061205(11), NM_170963(11), NM_170965(11), NM_170967(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_170959 NCBI Caenorhabditis elegans protein KINase family member (kin-1) (kin-1) mRNA, complete cds. 11/11 A 
NM_170961 NCBI Caenorhabditis elegans protein KINase family member (kin-1) (kin-1) mRNA, complete cds. 11/11 A 
NM_061205 NCBI Caenorhabditis elegans protein KINase family member (kin-1) (kin-1) mRNA, complete cds. 11/11 A 
NM_170963 NCBI Caenorhabditis elegans protein KINase family member (kin-1) (kin-1) mRNA, complete cds. 11/11 A 
NM_170965 NCBI Caenorhabditis elegans protein KINase family member (kin-1) (kin-1) mRNA, complete cds. 11/11 A 
NM_170967 NCBI Caenorhabditis elegans protein KINase family member (kin-1) (kin-1) mRNA, complete cds. 11/11 A 
SNAP00000000349 ENSEMBL cdna:SNAP chromosome:CEL140:I:14956801:14959685:1 11/11 None
ZK909.2j ENSEMBL cdna:known chromosome:CEL140:I:14927653:14959569:1 gene:ZK909.2 11/11 A 
ZK909.2i ENSEMBL cdna:known chromosome:CEL140:I:14931095:14959187:1 gene:ZK909.2 11/11 A 
ZK909.2b ENSEMBL cdna:known chromosome:CEL140:I:14941922:14959187:1 gene:ZK909.2 11/11 A 
ZK909.2k ENSEMBL cdna:known chromosome:CEL140:I:14942951:14959187:1 gene:ZK909.2 11/11 A 
ZK909.2e ENSEMBL cdna:known chromosome:CEL140:I:14945108:14959187:1 gene:ZK909.2 11/11 A 
ZK909.2d ENSEMBL cdna:known chromosome:CEL140:I:14948456:14959187:1 gene:ZK909.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
3565407 13 6 NM_061205 193173_at (11)
NM_170959 193173_at (11)
NM_170960 194143_x_at (11)
NM_170961 193173_at (11)
NM_170963 193173_at (11)
NM_170965 193173_at (11)
NM_170967 193173_at (11), 194147_x_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:14941952-14959118(+) 100.0 100.0
Public Domain and Genome References
Ensembl ZK909.2
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAD45621 Hypothetical protein ZK909.2j [Caenorhabditis elegans] emb|CAD45588.1| Hypothetical protein ZK909.2j [Caenorhabditis elegans] ref|NP_740955.1| protein KINase family member (kin-1) [Caenorhabditis elegans] 0.0
blast CAD45622 Hypothetical protein ZK909.2k [Caenorhabditis elegans] emb|CAD45589.1| Hypothetical protein ZK909.2k [Caenorhabditis elegans] ref|NP_740959.1| protein KINase family member (kin-1) [Caenorhabditis elegans] 0.0
blast CAD45616 Hypothetical protein ZK909.2e [Caenorhabditis elegans] emb|CAD45583.1| Hypothetical protein ZK909.2e [Caenorhabditis elegans] ref|NP_740961.1| protein KINase family member (kin-1) [Caenorhabditis elegans] sp|P21137|KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit (PKA C) 0.0
blast CAD45620 Hypothetical protein ZK909.2i [Caenorhabditis elegans] emb|CAD45587.1| Hypothetical protein ZK909.2i [Caenorhabditis elegans] ref|NP_740957.1| protein KINase family member (kin-1) [Caenorhabditis elegans] 0.0
blast CAB05035 Hypothetical protein ZK909.2b [Caenorhabditis elegans] emb|CAB04169.1| Hypothetical protein ZK909.2b [Caenorhabditis elegans] ref|NP_493606.1| protein KINase family member (kin-1) [Caenorhabditis elegans] 0.0
blast AAA51610 cAMP-dependent protein kinase catalytic subunit C [Caenorhabditis elegans] 0.0
blast CAE72620 Hypothetical protein CBG19814 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-68
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-68
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 9.0E-69
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-69
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-70
hanks 1.1.4 AGC group; AGC I Cyclic nucleotide regulated protein kinase (PKA & PKG); EcAPKa 1.0E-145
hanks 1.1.4 AGC group; AGC I Cyclic nucleotide regulated protein kinase (PKA & PKG); EcAPKa 1.0E-146
hanks 1.1.4 AGC group; AGC I Cyclic nucleotide regulated protein kinase (PKA & PKG); EcAPKa 1.0E-147
hanks 1.1.4 AGC group; AGC I Cyclic nucleotide regulated protein kinase (PKA & PKG); EcAPKa 1.0E-148
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-89
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 0.011
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-89
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-89
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-89
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-89
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-89
Pfam IPR000719 EMBL-EBI Protein kinase 5.7E-89
Sequence
Target Sequence 
>C. ELEGANS:193173_AT
ccgccctcgttctccaaaggagaatccaatggtcgactgttcgaggctctgtatccacgt
gtcgatggtcccgccgacacacgtcattttgtggaagaggtgcaagagccgactgagttt
gtgatcgccgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCGCCCTCGTTCTCCAAAGGAGAAT 174 1 973 Antisense
GGAGAATCCAATGGTCGACTGTTCG 703 519 991 Antisense
AATGGTCGACTGTTCGAGGCTCTGT 257 163 1000 Antisense
TCGACTGTTCGAGGCTCTGTATCCA 425 601 1005 Antisense
ACTGTTCGAGGCTCTGTATCCACGT 166 97 1008 Antisense
CCGCCGACACACGTCATTTTGTGGA 184 263 1043 Antisense
GACACACGTCATTTTGTGGAAGAGG 79 359 1048 Antisense
GTGGAAGAGGTGCAAGAGCCGACTG 270 491 1063 Antisense
AGAGGTGCAAGAGCCGACTGAGTTT 584 67 1068 Antisense
GCAAGAGCCGACTGAGTTTGTGATC 271 321 1074 Antisense
AGCCGACTGAGTTTGTGATCGCCGC 214 83 1079 Antisense
Sequence Source Affymetrix Proprietary Database