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[193156_s_at] serine proteinase inhibitor (kunitz type)

Description K10D3.4 /REP_DB=WormBase Gene ID /WP=CE06173 /TR=Q21418 /GB=CAA99886.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine proteinase inhibitor (kunitz type)
Cluster 6grp_highest_10_10 > 20      6grp_high1_10_10 > 14      6grp_highest_nonorm > 21      6grp_total > 04      4grp_total > 50      6grp_highest_sub > De      6grp_rule_based > S1      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2115
1 2 3 4 range
A 197.2
(-2.8)
P 		2021.1
(3)
P 		1397.5
(1)
P 		120.4
(-3)
A 		1901
B 234.3
(-2.5)
P 		2186.4
(3)
P 		1577.2
(1.3)
P 		71.5
(-3)
A 		2115
C 192.3
(-2.8)
P 		1834
(3)
P 		1475.6
(1.7)
P 		130.5
(-3)
A 		1704
avr 207.9
(-2.7) 		2013.8
(3) 		1483.4
(1.3) 		107.5
(-3) 		1906

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2006
1 2 3 4 5 6 range
A 2144.3
(3)
P 		1766.8
(1.7)
P 		874.7
(-1.3)
P 		1062.6
(-0.7)
P 		799.7
(-1.6)
P 		379.1
(-3)
P 		1765
B 1685.4
(3)
P 		1595.6
(2.6)
P 		950.1
(-0.2)
P 		1217.2
(1)
P 		587.5
(-1.8)
P 		306.8
(-3)
P 		1379
C 2312.3
(3)
P 		1482.8
(0.5)
P 		1441.5
(0.4)
P 		1054.2
(-0.8)
P 		753
(-1.7)
P 		336.2
(-3)
P 		1976
avr 2047.3
(3) 		1615.1
(1.5) 		1088.8
(-0.4) 		1111.3
(-0.3) 		713.4
(-1.7) 		340.7
(-3) 		1707
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 525
1 2 3 4 range
A 71.8
(-2.2)
P 		438.7
(3)
P 		365.3
(2)
P 		17.6
(-3)
A 		421
B 74.7
(-2.3)
P 		540
(3)
P 		365.5
(1)
P 		15.2
(-3)
A 		525
C 63.7
(-2.5)
P 		527.3
(3)
P 		514.3
(2.8)
P 		22
(-3)
A 		505
avr 70.1
(-2.4) 		502
(3) 		415
(1.9) 		18.3
(-3) 		484

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 765
1 2 3 4 5 6 range
A 395.3
(0.4)
P 		628.3
(3)
P 		190.5
(-1.9)
P 		269.5
(-1)
P 		241.3
(-1.3)
P 		92.3
(-3)
P 		536
B 586.4
(3)
P 		531.1
(2.3)
P 		230.7
(-1.5)
P 		322.4
(-0.4)
P 		238.7
(-1.4)
P 		114.4
(-3)
P 		472
C 857.1
(3)
P 		452.4
(-0.3)
P 		366.9
(-1)
P 		212
(-2.2)
P 		243.6
(-1.9)
P 		112.6
(-3)
P 		745
avr 612.9
(3) 		537.3
(2.1) 		262.7
(-1.1) 		268
(-1.1) 		241.2
(-1.4) 		106.4
(-3) 		507
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193156_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.798
Sequence Type Exemplar sequence
Representative Public ID K10D3.4 NCBI
Target Description K10D3.4 /REP_DB=WormBase Gene ID /WP=CE06173 /TR=Q21418 /GB=CAA99886.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine proteinase inhibitor (kunitz type)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059619(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059619 NCBI Caenorhabditis elegans K10D3.4 (K10D3.4) mRNA, complete cds. 11/11 None
SNAP00000021175 ENSEMBL cdna:SNAP chromosome:CEL140:I:7143221:7147803:-1 11/11 None
GENEFINDER00000021178 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7143221:7147803:-1 11/11 None
K10D3.4 ENSEMBL cdna:known chromosome:CEL140:I:7142870:7148105:-1 gene:K10D3.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7143151-7147734(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine proteinase inhibitor (kunitz type)
Ensembl K10D3.4
Entrez Gene 172452 Entrez gene
SwissProt Q21418 EMBL-EBI
WormBase CE06173 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA99886 Hypothetical protein K10D3.4 [Caenorhabditis elegans] ref|NP_492020.1| K10D3.4 [Caenorhabditis elegans] 0.0
blast CAE74254 Hypothetical protein CBG21943 [Caenorhabditis briggsae] 0.0
blast CAE62775 Hypothetical protein CBG06944 [Caenorhabditis briggsae] 1.0E-170
Protein Domains
Database ID Description E-Value
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 8.6E-32
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 5.7E-23
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.5E-16
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 5.8E-30
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.4E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-30
Sequence
Target Sequence 
>C. ELEGANS:193156_S_AT
tccggtggttgtcccgatggttacacttgttattcttcaccacttcttgatcagaatgtt
tgctgcggagcttcgactgaacttcaatctctctgccctgctgcttcaactccattcatt
tctgctctctcacttcaaccaatgcaatgtactccaaatgttgatggagcttgccctgga
aacttcttctgctggttctcaactacaacaacatcagtcaatgctttctactgctgcaga
tccccagactctgttgatacaggatactgcccaccacaacttgttcctgtaccaggagaa
aacggagcccagtacaaatactgctctccatcagctccactcaatgacgccatccagggt
tgtggagccaacagacattgccaattctccactaatttggaaagatatatctgttgtgga
cttgagtcagatgttcgattgccgaatgtttgcccaccacaaccagctaatttggttcca
gtcgagttggctggaaactataggacgtgcaatccatatgctcgtgctggaactccacaa
tcttgtccagacaactcagcatgtctttacacgggca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCGGTGGTTGTCCCGATGGTTACA 388 581 2152 Antisense
GTTACACTTGTTATTCTTCACCACT 135 447 2171 Antisense
GAATGTTTGCTGCGGAGCTTCGACT 412 331 2205 Antisense
TGATGGAGCTTGCCCTGGAAACTTC 81 567 2313 Antisense
TCTTCTGCTGGTTCTCAACTACAAC 575 617 2336 Antisense
CAATGCTTTCTACTGCTGCAGATCC 497 181 2370 Antisense
GCAGATCCCCAGACTCTGTTGATAC 354 313 2387 Antisense
ACCACAACTTGTTCCTGTACCAGGA 451 83 2424 Antisense
AACAGACATTGCCAATTCTCCACTA 454 135 2521 Antisense
GAACTCCACAATCTTGTCCAGACAA 348 349 2681 Antisense
AACTCAGCATGTCTTTACACGGGCA 15 101 2704 Antisense
Sequence Source Affymetrix Proprietary Database