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[193145_at] Human myeloid cell line protein 2 like

Description W08D2.7 /REP_DB=WormBase Gene ID /WP=CE06562 /TR=SW:Q23223 /GB=CAA94235.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Human myeloid cell line protein 2 like
Cluster 6grp_highest_10_10 > 66      6grp_high1_10_10 > 66      4grp_highest_8_8 > 42      4grp_high_8_8 > 41      6grp_highest_nonorm > 84      6grp_total > 66      4grp_total > 54      6grp_highest_sub > Da      6grp_high1_sub > Da      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 582
1 2 3 4 range
A 656.6
(3)
P 		422.9
(-0.7)
P 		385.8
(-1.3)
P 		278.9
(-3)
P 		378
B 696.6
(3)
P 		429.5
(-0.9)
P 		430
(-0.8)
P 		280.7
(-3)
P 		416
C 858.6
(3)
P 		402
(-1.7)
P 		540.4
(-0.3)
P 		276.6
(-3)
P 		582
avr 737.3
(3) 		418.1
(-1.2) 		452.1
(-0.7) 		278.7
(-3) 		459

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 688
1 2 3 4 5 6 range
A 422.8
(-3)
P 		545.5
(-1.6)
P 		921.6
(2.5)
P 		554.2
(-1.5)
P 		668
(-0.3)
P 		964.2
(3)
P 		541
B 706.6
(1)
P 		584.8
(-0.9)
P 		524.3
(-1.8)
P 		798.9
(2.4)
P 		444.4
(-3)
P 		841.6
(3)
P 		397
C 503.1
(-1.9)
P 		591.6
(-1.2)
P 		564.6
(-1.4)
P 		427
(-2.6)
P 		382.1
(-3)
P 		1070.5
(3)
P 		688
avr 544.2
(-2.4) 		574
(-2) 		670.2
(-0.8) 		593.4
(-1.8) 		498.2
(-3) 		958.8
(3) 		461
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 243
1 2 3 4 range
A 239.1
(3)
P 		91.8
(-1.5)
P 		100.9
(-1.2)
P 		40.8
(-3)
P 		198
B 222.1
(3)
P 		106.1
(-1.3)
P 		99.6
(-1.5)
P 		59.8
(-3)
P 		162
C 284.2
(3)
P 		115.6
(-1.3)
P 		188.3
(0.6)
P 		46.6
(-3)
P 		238
avr 248.5
(3) 		104.5
(-1.3) 		129.6
(-0.6) 		49.1
(-3) 		199

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 281
1 2 3 4 5 6 range
A 77.9
(-3)
P 		194
(1.4)
P 		200.7
(1.7)
P 		140.6
(-0.6)
P 		201.6
(1.7)
P 		234.7
(3)
P 		157
B 245.9
(0.8)
P 		194.7
(-0.8)
P 		127.3
(-3)
P 		211.6
(-0.3)
P 		180.5
(-1.3)
P 		313.8
(3)
P 		187
C 186.5
(-0.8)
P 		180.5
(-0.9)
P 		143.7
(-1.7)
P 		85.9
(-3)
P 		123.6
(-2.2)
P 		358.4
(3)
P 		273
avr 170.1
(-2.1) 		189.7
(-1.3) 		157.2
(-2.6) 		146
(-3) 		168.6
(-2.1) 		302.3
(3) 		156
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193145_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9170
Sequence Type Exemplar sequence
Representative Public ID W08D2.7 NCBI
Target Description W08D2.7 /REP_DB=WormBase Gene ID /WP=CE06562 /TR=SW:Q23223 /GB=CAA94235.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Human myeloid cell line protein 2 like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069356(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069356 NCBI Caenorhabditis elegans W08D2.7 (W08D2.7) mRNA, complete cds. 11/11 A 
SNAP00000011775 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9825673:9830456:1 11/11 None
GENEFINDER00000011777 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9825673:9830456:1 11/11 None
W08D2.7 ENSEMBL cdna:known chromosome:CEL140:IV:9825672:9830579:1 gene:W08D2.7 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9825678-9830462(+) 100.0 100.0
Public Domain and Genome References
Gene Title Human myeloid cell line protein 2 like
Ensembl W08D2.7
Entrez Gene 177824 Entrez gene
SwissProt Q23223 EMBL-EBI
WormBase CE06562 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:262906_AT ATP-dependent RNA helicase, putative at
ATGENOME1:12441_AT ATP-dependent RNA helicase, putative at
CANINE:1599863_AT similar to superkiller viralicidic activity 2-like 2 cfa
CANINE:1588878_AT similar to superkiller viralicidic activity 2-like 2 cfa
CANINE_2:CFA.2346.1.A1_S_AT similar to superkiller viralicidic activity 2-like 2 cfa
CANINE_2:CFA.2346.3.A1_A_AT similar to superkiller viralicidic activity 2-like 2 cfa
CANINE_2:CFA.2346.3.A1_AT similar to superkiller viralicidic activity 2-like 2 cfa
DROSGENOME1:152101_AT lethal (2) 35Df dm
DROSOPHILA_2:1636986_AT lethal (2) 35Df dm
CHICKEN:GGA.9870.1.S1_S_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) gga
CHICKEN:GGAAFFX.11436.1.S1_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) gga
HG-U133_PLUS_2:227447_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133B:227447_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HUGENEFL:D29641_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
U133_X3P:HS.41569.2.S1_3P_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
U133_X3P:HS.278608.0.S1_3P_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133A_2:212896_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133_PLUS_2:212896_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133A:212896_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U95AV2:41557_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
U133_X3P:HS2.384649.1.S1_3P_X_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
U133_X3P:HS.292437.0.A1_3P_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
U133_X3P:HS.274531.0.S1_3P_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133_PLUS_2:1562142_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133A_2:215805_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133_PLUS_2:215805_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133A:215805_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133_PLUS_2:243715_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U133B:243715_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U95E:83335_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U95B:42662_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U95B:59578_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HG-U95D:83535_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HU35KSUBC:RC_H93609_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HU35KSUBD:RC_AA406335_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
HU35KSUBD:RC_C14805_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) hs
MOUSE430_2:1447517_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) mm
MOE430B:1447517_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) mm
MU11KSUBA:AA217401_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) mm
MG-U74BV2:164961_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) mm
MOE430A:1426718_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) mm
MOUSE430A_2:1426718_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) mm
MOUSE430_2:1426718_AT superkiller viralicidic activity 2-like 2 (S. cerevisiae) mm
MOUSE430A_2:1437971_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) (Skiv2l2), mRNA mm
MOE430A:1437971_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) (Skiv2l2), mRNA mm
MOUSE430_2:1437971_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) (Skiv2l2), mRNA mm
MU19KSUBA:TC16381_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) (Skiv2l2), mRNA mm
MU19KSUBC:TC40056_AT Superkiller viralicidic activity 2-like 2 (S. cerevisiae) (Skiv2l2), mRNA mm
YEAST_2:1774018_AT Dead-box family ATP dependent helicase required for mRNA export from the nucleus; co-factor of the exosome complex, required for 3' end formation of 5.8S rRNA Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
4386 helicase activity inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
8026 ATP-dependent helicase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94235 Hypothetical protein W08D2.7 [Caenorhabditis elegans] ref|NP_501757.1| W08D2.7 [Caenorhabditis elegans] sp|Q23223|YH2O_CAEEL Putative helicase W08D2.7 0.0
blast CAE59981 Hypothetical protein CBG03473 [Caenorhabditis briggsae] 0.0
blast CAG30992 hypothetical protein [Gallus gallus] ref|NP_001012962.1| superkiller viralicidic activity 2-like 2 [Gallus gallus] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001650 EMBL-EBI Helicase, C-terminal 1.4E-12
Pfam IPR001410 EMBL-EBI DEAD/DEAH box helicase 8.5E-39
Pfam IPR001650 EMBL-EBI Helicase, C-terminal 1.4E-12
Pfam IPR001410 EMBL-EBI DEAD/DEAH box helicase 8.5E-39
Sequence
Target Sequence 
>C. ELEGANS:193145_AT
gggaaacgatgatgctcttgttcttaagggatccgttgcctgtgaattatccgcttcaga
tgagttgatcttgacagaaatgctcttgaaaggaattttcaatacgcttgatgtcgctca
aacggctgctctactctcgtgtttcgtgttccaagacaaatgtgcagctccgaagttggc
aacagaacttcagacatgtctcagtgaacttcatgaacaagctagaaatgtggcgaaggt
atcaaatgaatgtaaaatggaagttatggaggacaagtatgtcagtagtttcaatcctgg
actcatggatgtcgtat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGAAACGATGATGCTCTTGTTCTT 85 495 2559 Antisense
GCTCTTGTTCTTAAGGGATCCGTTG 74 299 2572 Antisense
GATCCGTTGCCTGTGAATTATCCGC 320 417 2588 Antisense
GAATTATCCGCTTCAGATGAGTTGA 353 325 2602 Antisense
TACGCTTGATGTCGCTCAAACGGCT 433 649 2661 Antisense
TCTCGTGTTTCGTGTTCCAAGACAA 330 611 2693 Antisense
TGTGCAGCTCCGAAGTTGGCAACAG 656 555 2719 Antisense
GGCAACAGAACTTCAGACATGTCTC 323 535 2736 Antisense
TCAGACATGTCTCAGTGAACTTCAT 347 623 2748 Antisense
ATGTCAGTAGTTTCAATCCTGGACT 334 49 2837 Antisense
AATCCTGGACTCATGGATGTCGTAT 497 167 2851 Antisense
Sequence Source Affymetrix Proprietary Database