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[193134_at] G protein coupled receptor

Description C38C10.1 /REP_DB=WormBase Gene ID /WP=CE00104 /GEN=tkr-1 /TR=SW:Q03566 /GB=CAA79546.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=G protein coupled receptor
Cluster 6grp_high1_10_10 > 03      6grp_total > 24      4grp_total > 23      6grp_cgc > 21      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 307
1 2 3 4 range
A 274
(3)
P 		98.1
(-2)
A 		61.9
(-3)
A 		268.9
(2.9)
P 		212
B 318.5
(3)
P 		88.1
(-2)
A 		44.1
(-3)
A 		250.3
(1.5)
P 		274
C 350.8
(3)
P 		90.6
(-2.4)
A 		63.2
(-3)
A 		217.8
(0.2)
P 		288
avr 314.4
(3) 		92.3
(-2.2) 		56.4
(-3) 		245.7
(1.4) 		258

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 117
1 2 3 4 5 6 range
A 197.3
(3)
P 		184.5
(2.2)
P 		156.7
(0.4)
P 		116.9
(-2.1)
P 		120.1
(-1.9)
P 		102.7
(-3)
A 		95
B 200.5
(3)
P 		146.8
(0.2)
P 		143.6
(0.1)
P 		106.4
(-1.8)
A 		137.9
(-0.2)
P 		83.4
(-3)
P 		117
C 163.4
(2.9)
P 		157.7
(2.2)
P 		164.6
(3)
P 		144.6
(0.6)
P 		114.9
(-3)
P 		146
(0.8)
P 		50
avr 187.1
(3) 		163
(1.1) 		155
(0.5) 		122.6
(-2.1) 		124.3
(-1.9) 		110.7
(-3) 		76
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 106
1 2 3 4 range
A 99.8
(3)
P 		21.3
(-2.6)
A 		16.2
(-3)
A 		39.4
(-1.3)
P 		84
B 101.6
(3)
P 		21.8
(-2.2)
A 		10.2
(-3)
A 		53.3
(-0.2)
P 		91
C 116.1
(3)
P 		26
(-2.7)
A 		22
(-3)
A 		36.7
(-2.1)
P 		94
avr 105.8
(3) 		23
(-2.5) 		16.1
(-3) 		43.1
(-1.2) 		90

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 45
1 2 3 4 5 6 range
A 36.4
(-1.3)
P 		65.6
(3)
P 		34.1
(-1.7)
P 		29.7
(-2.3)
P 		36.2
(-1.3)
P 		25
(-3)
A 		41
B 69.8
(3)
P 		48.9
(-0)
P 		34.9
(-2)
P 		28.2
(-3)
A 		56
(1)
P 		31.1
(-2.6)
P 		42
C 60.6
(3)
P 		48.1
(0.6)
P 		41.9
(-0.6)
P 		29.1
(-3)
P 		37.2
(-1.5)
P 		48.9
(0.8)
P 		32
avr 55.6
(3) 		54.2
(2.7) 		37
(-1.2) 		29
(-3) 		43.1
(0.2) 		35
(-1.6) 		27
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193134_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8064
Sequence Type Exemplar sequence
Representative Public ID C38C10.1 NCBI
Target Description C38C10.1 /REP_DB=WormBase Gene ID /WP=CE00104 /GEN=tkr-1 /TR=SW:Q03566 /GB=CAA79546.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=G protein coupled receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066663(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066663 NCBI Caenorhabditis elegans TachyKinin Receptor family member (tkr-1) (tkr-1) mRNA, complete cds. 11/11 None
SNAP00000012402 ENSEMBL cdna:SNAP chromosome:CEL140:III:9383697:9389719:1 11/11 None
GENEFINDER00000012409 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:9385838:9387501:1 11/11 None
C38C10.1 ENSEMBL cdna:known chromosome:CEL140:III:9385559:9387501:1 gene:C38C10.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:9385554-9387497(+) 100.0 100.0
Public Domain and Genome References
Gene Title G protein coupled receptor
Gene Symbol tkr-1
Ensembl C38C10.1
Entrez Gene 192055 Entrez gene
SwissProt Q03566 EMBL-EBI
WormBase CE00104 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5886 plasma membrane inferred from electronic annotation QuickGO AmiGO
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
4995 tachykinin receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA79546 Hypothetical protein C38C10.1 [Caenorhabditis elegans] ref|NP_499064.1| TachyKinin Receptor family member (tkr-1) [Caenorhabditis elegans] sp|Q03566|YLD1_CAEEL Probable G-protein coupled receptor C38C10.1 0.0
blast CAE65226 Hypothetical protein CBG10102 [Caenorhabditis briggsae] 0.0
blast CAE65226 Hypothetical protein CBG10102 [Caenorhabditis briggsae] 1.0E-179
blast AAK29785 Hypothetical protein C49A9.7 [Caenorhabditis elegans] ref|NP_500930.1| C49A9.7 [Caenorhabditis elegans] 2.0E-54
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 4.4E-54
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 4.4E-54
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 3.5E-40
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_499064.1 7 15-37,49-71,84-106,127-149,181-203,226-248,263-285
C38C10.1 7 15-37,49-71,84-106,127-149,181-203,226-248,263-285
SNAP00000012402 7 44-66,79-101,116-138,159-181,213-235,258-280,295-317
GENEFINDER00000012409 5 32-54,75-97,129-151,174-196,211-233
Sequence
Target Sequence 
>C. ELEGANS:193134_AT
ctcacgtttgttcagcaccagttaatactttctttgaaaaagtgctctttgggattcaat
atgctctacctataatcattttgggatcaacgttcacacggattgccgttgcatttcgag
caacaaatgaagccactgacagtagtctgaagaacaatcacacacgcgcaaagagcaagg
cagtaaaaatgctcttcctaatggtcgttgcattcgttgtctgctggcttccataccaca
tttatcacgcattcgctcttgaagaattcttcgatgcagctcgtggaaaatatgcgtatt
tgttgatttactggattgcaatgtctagttgtgcatacaatccaattatttattgttttg
ccaacgaaagattccgcattggcttccggtacgtcttccgatggattccagtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTCACGTTTGTTCAGCACCAGTTAA 201 227 509 Antisense
GGGATTCAATATGCTCTACCTATAA 305 495 559 Antisense
GGGATCAACGTTCACACGGATTGCC 558 493 591 Antisense
CACGGATTGCCGTTGCATTTCGAGC 248 199 605 Antisense
GAACAATCACACACGCGCAAAGAGC 124 353 660 Antisense
AAATGCTCTTCCTAATGGTCGTTGC 576 119 695 Antisense
TGCTGGCTTCCATACCACATTTATC 318 583 730 Antisense
CACATTTATCACGCATTCGCTCTTG 60 197 745 Antisense
GAATTCTTCGATGCAGCTCGTGGAA 351 325 772 Antisense
GAAAGATTCCGCATTGGCTTCCGGT 518 359 874 Antisense
GTACGTCTTCCGATGGATTCCAGTG 311 459 897 Antisense
Sequence Source Affymetrix Proprietary Database