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[193120_at] Potassium channel protein

Description F22B7.7 /REP_DB=WormBase Gene ID /WP=CE00160 /GEN=twk-8 /TR=SW:P34410 /GB=AAA65460.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Potassium channel protein
Cluster 6grp_total > 57      4grp_total > 03      6grp_cgc > 37      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2076
1 2 3 4 range
A 176.2
(-2.6)
P
57.5
(-2.9)
A
35.3
(-3)
A
2078.7
(3)
P
2043
B 153
(-2.6)
P
88.3
(-2.8)
A
41.7
(-3)
A
1691.9
(3)
P
1650
C 145.7
(-2.5)
P
3
(-3)
A
63.2
(-2.8)
A
1613.4
(3)
P
1610
avr 158.3
(-2.6)
49.6
(-3)
46.7
(-3)
1794.7
(3)
1748

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 132
1 2 3 4 5 6 range
A 126.4
(-0.6)
P
98.3
(-2.2)
P
83.2
(-3)
A
112.3
(-1.4)
P
85.4
(-2.9)
P
189.9
(3)
P
107
B 161.5
(0)
P
126.7
(-2)
A
110.1
(-3)
A
180.6
(1.1)
P
132.6
(-1.7)
P
212.7
(3)
P
103
C 106.6
(-1.8)
P
123.1
(-1.1)
A
107.4
(-1.8)
M
121.6
(-1.1)
P
80.6
(-3)
M
211.6
(3)
P
131
avr 131.5
(-1.2)
116
(-2.1)
100.2
(-3)
138.2
(-0.8)
99.5
(-3)
204.7
(3)
105
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 360
1 2 3 4 range
A 64.1
(-1.9)
P
12.5
(-2.9)
A
9.2
(-3)
A
304.3
(3)
P
295
B 48.8
(-2.3)
P
21.8
(-2.8)
A
9.7
(-3)
A
360.5
(3)
P
351
C 48.2
(-2)
P
0.9
(-3)
A
22
(-2.5)
A
272
(3)
P
271
avr 53.7
(-2.2)
11.7
(-3)
13.6
(-3)
312.3
(3)
301

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 61
1 2 3 4 5 6 range
A 23.3
(-1.9)
P
35
(0.6)
P
18.1
(-3)
A
28.5
(-0.8)
P
25.8
(-1.4)
P
46.2
(3)
P
28
B 56.2
(0.4)
P
42.2
(-1.2)
A
26.7
(-3)
A
47.8
(-0.6)
P
53.9
(0.1)
P
79.3
(3)
P
53
C 39.5
(-1)
P
37.6
(-1.3)
A
27.3
(-2.6)
M
24.4
(-3)
P
26.1
(-2.8)
M
70.8
(3)
P
46
avr 39.7
(-0.7)
38.3
(-0.9)
24
(-3)
33.6
(-1.6)
35.3
(-1.4)
65.4
(3)
41
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193120_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6220
Sequence Type Exemplar sequence
Representative Public ID F22B7.7 NCBI
Target Description F22B7.7 /REP_DB=WormBase Gene ID /WP=CE00160 /GEN=twk-8 /TR=SW:P34410 /GB=AAA65460.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Potassium channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066502(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_066502 NCBI Caenorhabditis elegans TWiK family of potassium channels family member (twk-7) (twk-7) mRNA, complete cds. 11/11 None
SNAP00000003832 ENSEMBL cdna:SNAP chromosome:CEL140:III:8634483:8635871:-1 11/11 None
GENEFINDER00000003844 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:8634483:8647754:-1 11/11 None
F22B7.7 ENSEMBL cdna:known chromosome:CEL140:III:8633981:8643642:-1 gene:F22B7.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:8634477-8637596(-) 100.0 100.0
Public Domain and Genome References
Gene Title Potassium channel protein
Gene Symbol twk-7
Ensembl F22B7.7
Entrez Gene 192073 Entrez gene
SwissProt P34410 EMBL-EBI
WormBase CE37508 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1637725_AT dm
DROSGENOME1:144878_AT dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5267 potassium channel activity inferred from electronic annotation QuickGO AmiGO
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
20037 heme binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAU87822 Twik family of potassium channels protein 7 [Caenorhabditis elegans] ref|NP_498903.3| TWiK family of potassium channels family member (twk-7) [Caenorhabditis elegans] sp|P34410|TWK7_CAEEL TWiK family of potassium channels protein 0.0
blast CAE75020 Hypothetical protein CBG22924 [Caenorhabditis briggsae] 1.0E-155
blast CAE75022 Hypothetical protein CBG22926 [Caenorhabditis briggsae] 1.0E-83
blast CAE75020 Hypothetical protein CBG22924 [Caenorhabditis briggsae] 4.0E-82
blast AAU87822 Twik family of potassium channels protein 7 [Caenorhabditis elegans] ref|NP_498903.3| TWiK family of potassium channels family member (twk-7) [Caenorhabditis elegans] sp|P34410|TWK7_CAEEL TWiK family of potassium channels protein 4.0E-82
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 8.7E-19
Pfam IPR005821 EMBL-EBI Ion transport protein 8.1E-13
Pfam IPR005821 EMBL-EBI Ion transport protein 8.7E-19
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_498903.3 6 162-184,265-287,294-316,369-388,395-414,424-446
F22B7.7 6 162-184,265-287,294-316,369-388,395-414,424-446
SNAP00000003832 4 12-31,35-57,69-91,106-128
GENEFINDER00000003844 7 279-301,380-402,407-428,483-505,510-529,541-563,578-600
Sequence
Target Sequence
>C. ELEGANS:193120_AT
aattcctgcattcctggtattagctattctgatagtatatacagcgtttggcggtgtcct
aatgtcaaaattagagccgtggtctttcttcacttcattctactggtccttcattacaat
gactactgtcgggtttggcgacttgatgcccagaagggacggatacatgtatatcatatt
gctctatatcattttaggtaaattttcaatgaaaaaaaaacaaaaattcaaaatattttt
aggtcttgcaataactacaatgtgcattgatttggtaggagtacagtatattcgaaagat
tcattatttcggaagaaaaattcaagacgctagatctgcattggcggttgtaggaggaaa
ggtagtccttgtatcagaactctacgcaaatttaatgcaaaagcgagctcgtaacatgtc
ccgagaagcttttatagtggagaatctctatgtttccaaacacatcataccattcatacc
aactgatatccgatgtattcgatatattgatcaaactgccgatgctgctaccatttccac
gtcatcgtctgcaatt


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
AATTCCTGCATTCCTGGTATTAGCT 707 177 405 Antisense
TATACAGCGTTTGGCGGTGTCCTAA 124 657 442 Antisense
ATTAGAGCCGTGGTCTTTCTTCACT 264 13 474 Antisense
TTCATTCTACTGGTCCTTCATTACA 574 689 498 Antisense
GGGTTTGGCGACTTGATGCCCAGAA 645 495 535 Antisense
GACGCTAGATCTGCATTGGCGGTTG 201 381 730 Antisense
AGTCCTTGTATCAGAACTCTACGCA 120 49 768 Antisense
AAAGCGAGCTCGTAACATGTCCCGA 212 125 804 Antisense
ACACATCATACCATTCATACCAACT 570 109 864 Antisense
TTGATCAAACTGCCGATGCTGCTAC 39 707 911 Antisense
CATTTCCACGTCATCGTCTGCAATT 106 215 936 Antisense
Sequence Source Affymetrix Proprietary Database