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[193068_at] Oligopeptide transporter

Description K04E7.2 /REP_DB=WormBase Gene ID /WP=CE25039 /GEN=pep-2 /TR=SW:Q21219 /GB=AAA80411.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Oligopeptide transporter
Cluster 6grp_highest_10_10 > 41      6grp_high1_10_10 > 16      4grp_highest_8_8 > 33      4grp_high_8_8 > 58      6grp_highest_nonorm > 20      6grp_total > 15      4grp_total > 61      6grp_highest_sub > De      6grp_cgc > 23      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2585
1 2 3 4 range
A 3170.6
(3)
P 		2226.7
(0.4)
P 		2694.3
(1.7)
P 		984.7
(-3)
P 		2186
B 3170.1
(3)
P 		2271.3
(0.7)
P 		2546.4
(1.4)
P 		846
(-3)
P 		2324
C 3402.3
(3)
P 		2201.5
(0.2)
P 		2633.6
(1.2)
P 		816.9
(-3)
P 		2585
avr 3247.7
(3) 		2233.2
(0.4) 		2624.8
(1.4) 		882.5
(-3) 		2365

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1711
1 2 3 4 5 6 range
A 2175.4
(3)
P 		1826.2
(1.7)
P 		804.3
(-2)
P 		793.3
(-2)
P 		514.1
(-3)
P 		540.9
(-2.9)
P 		1661
B 1822.8
(3)
P 		1451.2
(1.4)
P 		906.4
(-1)
P 		733
(-1.8)
P 		464.3
(-3)
P 		475.1
(-3)
P 		1359
C 1979.4
(3)
P 		1532
(1.2)
P 		1147
(-0.3)
P 		807.8
(-1.7)
P 		538.2
(-2.8)
P 		480.8
(-3)
P 		1499
avr 1992.5
(3) 		1603.1
(1.4) 		952.6
(-1.2) 		778
(-1.9) 		505.5
(-3) 		498.9
(-3) 		1494
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1017
1 2 3 4 range
A 1154.4
(3)
P 		483.4
(-1)
P 		704.4
(0.3)
P 		144.1
(-3)
P 		1010
B 1010.9
(3)
P 		561
(-0.2)
P 		590.1
(-0)
P 		180.3
(-3)
P 		831
C 1126.2
(3)
P 		632.9
(0)
P 		917.9
(1.7)
P 		137.7
(-3)
P 		989
avr 1097.2
(3) 		559.1
(-0.4) 		737.5
(0.7) 		154
(-3) 		943

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 602
1 2 3 4 5 6 range
A 401
(0.1)
P 		649.5
(3)
P 		175.2
(-2.5)
P 		201.2
(-2.2)
P 		155.1
(-2.7)
P 		131.7
(-3)
P 		518
B 634.2
(3)
P 		483.1
(1)
P 		220.1
(-2.4)
P 		194.2
(-2.8)
P 		188.7
(-2.8)
P 		177.2
(-3)
P 		457
C 733.7
(3)
P 		467.5
(0.2)
P 		291.9
(-1.6)
P 		162.5
(-3)
P 		174.1
(-2.9)
P 		161
(-3)
P 		573
avr 589.6
(3) 		533.4
(2.2) 		229.1
(-2) 		186
(-2.6) 		172.6
(-2.8) 		156.6
(-3) 		433
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193068_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15999
Sequence Type Exemplar sequence
Representative Public ID K04E7.2 NCBI
Target Description K04E7.2 /REP_DB=WormBase Gene ID /WP=CE25039 /GEN=pep-2 /TR=SW:Q21219 /GB=AAA80411.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Oligopeptide transporter
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076686(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076686 NCBI Caenorhabditis elegans OligoPeptide Transporter family member (opt-2) (opt-2) mRNA, complete cds. 11/11 None
GENEFINDER00000025388 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6456988:6461596:1 11/11 None
SNAP00000025384 ENSEMBL cdna:SNAP chromosome:CEL140:X:6457733:6461596:1 11/11 None
K04E7.2 ENSEMBL cdna:known chromosome:CEL140:X:6456926:6461720:1 gene:K04E7.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6456987-6461596(+) 100.0 100.0
Public Domain and Genome References
Gene Title Oligopeptide transporter
Gene Symbol opt-2
Ensembl K04E7.2
Entrez Gene 180919 Entrez gene
SwissProt Q21219 EMBL-EBI
WormBase CE25039 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:15583_S_AT peptide transporter (PTR2-B) / oligopeptide transporter 1-1, putative (OPT1-1) at
ATH1-121501:265220_AT peptide transporter (PTR2-B) / oligopeptide transporter 1-1, putative (OPT1-1) at
DROSOPHILA_2:1634074_A_AT yin dm
DROSGENOME1:153044_AT yin dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6857 oligopeptide transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
16324 apical plasma membrane inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5215 transporter activity inferred from electronic annotation QuickGO AmiGO
15198 oligopeptide transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA80411 Oligopeptide transporter protein 2 [Caenorhabditis elegans] ref|NP_509087.1| OligoPeptide Transporter family member (opt-2) [Caenorhabditis elegans] sp|Q21219|OPT2_CAEEL Oligopeptide transporter 2 (Di-/tri-peptide transporter CPTB) 0.0
blast AAC39119 low-affinity peptide transporter [Caenorhabditis elegans] 0.0
blast CAE61262 Hypothetical protein CBG05068 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000109 EMBL-EBI TGF-beta receptor, type I/II extracellular region 1.0E-126
Pfam IPR000109 EMBL-EBI TGF-beta receptor, type I/II extracellular region 6.4E-7
Pfam IPR000109 EMBL-EBI TGF-beta receptor, type I/II extracellular region 1.0E-126
Pfam IPR000109 EMBL-EBI TGF-beta receptor, type I/II extracellular region 6.4E-7
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509087.1 10 84-106,113-135,148-170,183-205,220-242,319-336,367-389,401-419,736-758,765-787
K04E7.2 10 84-106,113-135,148-170,183-205,220-242,319-336,367-389,401-419,736-758,765-787
GENEFINDER00000025388 10 84-106,113-135,148-170,183-205,220-242,319-336,367-389,401-419,736-758,765-787
SNAP00000025384 11 21-38,48-67,74-96,109-131,144-166,181-203,280-297,328-350,362-380,697-719,726-748
Sequence
Target Sequence 
>C. ELEGANS:193068_AT
gcaacactcgttgctccaacaaattacggttttcacagagttaagcagggaggtgtgttc
atctatgcattgaccggaacatacgaaaatccaaagatccacgagcttcaaattgtacag
tccaatagtgtgtcgattctttggcagattccacaaatcgttgtcatcacggcagcagaa
attttgttctcaattaccggatacgaatttgcatattctcagtctgccccatcaatgaaa
gctctggtacaagccctctggctcttgaccactgctgctggagattccatcattgtagtc
atcacaatccttaacttatttgaaaatatggccgtcgaattctttgtctatgctgctgcg
atgtttgtagtta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCAACACTCGTTGCTCCAACAAATT 538 317 1966 Antisense
AGGGAGGTGTGTTCATCTATGCATT 283 59 2012 Antisense
GATCCACGAGCTTCAAATTGTACAG 341 415 2061 Antisense
GTGTCGATTCTTTGGCAGATTCCAC 583 487 2095 Antisense
AAATCGTTGTCATCACGGCAGCAGA 473 117 2120 Antisense
AATTTGCATATTCTCAGTCTGCCCC 283 175 2171 Antisense
ATGAAAGCTCTGGTACAAGCCCTCT 290 45 2200 Antisense
TGACCACTGCTGCTGGAGATTCCAT 667 569 2231 Antisense
GAGATTCCATCATTGTAGTCATCAC 518 397 2246 Antisense
TATGGCCGTCGAATTCTTTGTCTAT 303 655 2292 Antisense
TATGCTGCTGCGATGTTTGTAGTTA 516 657 2314 Antisense
Sequence Source Affymetrix Proprietary Database