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[193052_at] WD domain, G-beta repeats (4 domains)

Description Y53C12B.1 /REP_DB=WormBase Gene ID /WP=CE14894 /TR=O18215 /GB=CAB16490.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=WD domain, G-beta repeats (4 domains)
Cluster 6grp_highest_10_10 > 66      6grp_high1_10_10 > 75      4grp_highest_8_8 > 40      4grp_high_8_8 > 43      6grp_highest_nonorm > 86      6grp_total > 65      4grp_total > 53      6grp_highest_sub > Da      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 503
1 2 3 4 range
A 1198.9
(2.6)
P 		1227.3
(3)
P 		860.5
(-2.5)
P 		824.6
(-3)
P 		403
B 1220.5
(3)
P 		1176.8
(1.5)
P 		1206.9
(2.5)
P 		1046.2
(-3)
P 		174
C 1287.8
(3)
P 		1081.3
(0.5)
P 		1110.3
(0.9)
P 		784.4
(-3)
P 		503
avr 1235.7
(3) 		1161.8
(1.7) 		1059.2
(-0) 		885.1
(-3) 		351

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 580
1 2 3 4 5 6 range
A 644.4
(-3)
P 		746.7
(-1.5)
P 		863.4
(0.2)
P 		723.5
(-1.8)
P 		927.7
(1.1)
P 		1055.4
(3)
P 		411
B 859.9
(-2)
P 		1001.5
(0.4)
P 		1151.5
(3)
P 		1030.3
(0.9)
P 		802.3
(-3)
P 		1077.6
(1.7)
P 		349
C 755
(-1.9)
P 		975.5
(0.4)
P 		660.5
(-2.9)
P 		1115.7
(1.9)
P 		654.5
(-3)
P 		1224.3
(3)
P 		570
avr 753.1
(-3) 		907.9
(-0.5) 		891.8
(-0.7) 		956.5
(0.3) 		794.8
(-2.3) 		1119.1
(3) 		366
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 316
1 2 3 4 range
A 436.5
(3)
P 		266.4
(-0.2)
P 		225
(-1)
P 		120.7
(-3)
P 		316
B 389.2
(3)
P 		290.6
(-0.6)
P 		279.7
(-1)
P 		223
(-3)
P 		166
C 426.3
(3)
P 		310.9
(0.6)
P 		387
(2.2)
P 		132.3
(-3)
P 		294
avr 417.3
(3) 		289.3
(0) 		297.2
(0.2) 		158.7
(-3) 		259

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 291
1 2 3 4 5 6 range
A 118.8
(-3)
P 		265.6
(2.5)
P 		188
(-0.4)
P 		183.5
(-0.6)
P 		279.9
(3)
P 		257
(2.1)
P 		161
B 299.2
(-1.8)
P 		333.3
(-0.2)
P 		279.6
(-2.7)
P 		272.9
(-3)
P 		326
(-0.5)
P 		401.8
(3)
P 		129
C 279.8
(-0.2)
P 		297.7
(0.2)
P 		168.1
(-3)
P 		224.4
(-1.6)
P 		211.8
(-1.9)
P 		409.9
(3)
P 		242
avr 232.6
(-2.1) 		298.9
(0.6) 		211.9
(-3) 		226.9
(-2.4) 		272.6
(-0.5) 		356.2
(3) 		144
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193052_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3755
Sequence Type Exemplar sequence
Representative Public ID Y53C12B.1 NCBI
Target Description Y53C12B.1 /REP_DB=WormBase Gene ID /WP=CE14894 /TR=O18215 /GB=CAB16490.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=WD domain, G-beta repeats (4 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063699(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063699 NCBI Caenorhabditis elegans Y53C12B.1 (Y53C12B.1) mRNA, complete cds. 11/11 None
SNAP00000006653 ENSEMBL cdna:SNAP chromosome:CEL140:II:9743042:9745978:-1 11/11 None
GENEFINDER00000006678 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:9743042:9745978:-1 11/11 None
Y53C12B.1 ENSEMBL cdna:known chromosome:CEL140:II:9743042:9745978:-1 gene:Y53C12B.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9743038-9745975(-) 100.0 100.0
Public Domain and Genome References
Gene Title WD domain, G-beta repeats (4 domains)
Ensembl Y53C12B.1
Entrez Gene 190203 Entrez gene
SwissProt O18215 EMBL-EBI
WormBase CE14894 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:246457_AT transducin family protein / WD-40 repeat family protein at
CANINE_2:CFA.17438.1.S1_S_AT similar to transducin beta-like 3 cfa
CANINE_2:CFAAFFX.29714.1.S1_S_AT similar to transducin beta-like 3 cfa
CANINE_2:CFAAFFX.29717.1.S1_S_AT similar to transducin beta-like 3 cfa
DROSOPHILA_2:1627977_AT dm
DROSGENOME1:141261_AT dm
CHICKEN:GGA.13178.1.S1_AT transducin (beta)-like 3 gga
CHICKEN:GGAAFFX.11554.1.S1_AT transducin (beta)-like 3 gga
CHICKEN:GGAAFFX.11554.1.S1_S_AT transducin (beta)-like 3 gga
CHICKEN:GGAAFFX.3490.1.S1_S_AT transducin (beta)-like 3 gga
HG-U133_PLUS_2:209820_S_AT transducin (beta)-like 3 hs
HG-U133A:209820_S_AT transducin (beta)-like 3 hs
HG-U133A_2:209820_S_AT transducin (beta)-like 3 hs
HUGENEFL:U02609_AT transducin (beta)-like 3 hs
U133_X3P:G12803114_3P_S_AT transducin (beta)-like 3 hs
HG-U95AV2:41603_AT transducin (beta)-like 3 hs
MG-U74AV2:96531_AT transducin (beta)-like 3 mm
MG-U74AV2:92259_AT transducin (beta)-like 3 mm
MG-U74BV2:116562_AT transducin (beta)-like 3 mm
MG-U74BV2:113160_AT transducin (beta)-like 3 mm
MG-U74CV2:166512_R_AT transducin (beta)-like 3 mm
MOE430A:1415750_AT transducin (beta)-like 3 mm
MOE430B:1415750_AT transducin (beta)-like 3 mm
MOUSE430A_2:1415750_AT transducin (beta)-like 3 mm
MOUSE430_2:1415750_AT transducin (beta)-like 3 mm
MOE430B:1447660_AT transducin (beta)-like 3 mm
MOUSE430_2:1447660_AT transducin (beta)-like 3 mm
MOE430B:1447782_X_AT transducin (beta)-like 3 mm
MOUSE430_2:1447782_X_AT transducin (beta)-like 3 mm
MU19KSUBA:TC15885_AT transducin (beta)-like 3 mm
MU19KSUBA:TC22309_AT Transducin (beta)-like 3 (Tbl3), mRNA mm
MU19KSUBB:TC31115_AT Transducin (beta)-like 3 (Tbl3), mRNA mm
MU11KSUBA:AA536728_RC_AT Transducin (beta)-like 3 (Tbl3), mRNA mm
RAE230A:1372661_AT transducin (beta)-like 3 (predicted) rn
RAT230_2:1372661_AT transducin (beta)-like 3 (predicted) rn
YEAST_2:1771304_AT Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA Sc
Protein Similarities
Method ID Description E-Value
blast CAB16490 Hypothetical protein Y53C12B.1 [Caenorhabditis elegans] ref|NP_496100.1| Y53C12B.1 [Caenorhabditis elegans] 0.0
blast CAE57979 Hypothetical protein CBG01041 [Caenorhabditis briggsae] 0.0
blast NP_001017314 transducin (beta)-like 3 [Xenopus tropicalis] 1.0E-127
Protein Domains
Database ID Description E-Value
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.7E-7
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0090
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 4.3E-4
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 8.7E-8
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.1E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.5E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 3.4E-5
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 3.9E-6
Sequence
Target Sequence 
>C. ELEGANS:193052_AT
gaatgttccattgatgcgcatactgacaaaatttggtcgctttcgaaaaatcataacgag
tcagagtttgtgactgctggaactgatgggcggattgttgtctggaaggatgttacagag
gagaaacaaaaagccgaggataataagagaagagaggctattgaacaagatcagactttg
acaaatttattgagtcagaagagatattcggaagctctcgtgtttgcactgactctagcc
aaaccgttttgtgcttttaaggttataaatgctctgatggctgaggagacaccagaagaa
ctcggttccgcaattcgccgccttgacacccgtcaaattgagattctactgcaattcaca
gtgaaatggaacacgaatagtcgaacatcgtcagttgcacaacgagttttgtacgaaatt
gttcatatcgtggatccagaggagttagtgtcaatgcccggtgcatatggatatattgaa
tcattcctaccgtacacccaacggcacatggatcga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATGTTCCATTGATGCGCATACTG 605 329 1810 Antisense
GTGACTGCTGGAACTGATGGGCGGA 193 483 1879 Antisense
GATGGGCGGATTGTTGTCTGGAAGG 570 407 1894 Antisense
ATTCGGAAGCTCTCGTGTTTGCACT 489 7 2015 Antisense
GACTCTAGCCAAACCGTTTTGTGCT 459 373 2040 Antisense
AGAAGAACTCGGTTCCGCAATTCGC 339 73 2103 Antisense
CCGCCTTGACACCCGTCAAATTGAG 622 259 2127 Antisense
AGTCGAACATCGTCAGTTGCACAAC 362 61 2188 Antisense
AGGAGTTAGTGTCAATGCCCGGTGC 82 55 2249 Antisense
TATTGAATCATTCCTACCGTACACC 573 665 2283 Antisense
GTACACCCAACGGCACATGGATCGA 521 459 2301 Antisense
Sequence Source Affymetrix Proprietary Database