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[193050_at] ER lumen protein retaining receptor

Description C28H8.4 /REP_DB=WormBase Gene ID /WP=CE01826 /TR=SW:Q09473 /GB=AAA62292.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=ER lumen protein retaining receptor
Cluster 6grp_highest_10_10 > 28      6grp_high1_10_10 > 71      4grp_highest_8_8 > 10      4grp_high_8_8 > 54      6grp_highest_nonorm > 45      6grp_total > 72      4grp_total > 57      6grp_highest_sub > 04      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1126
1 2 3 4 range
A 1455.6
(-0.9)
P 		1820.3
(1)
P 		2193.9
(3)
P 		1068.1
(-3)
P 		1126
B 1268.8
(-3)
P 		1994.6
(1.8)
P 		2184.9
(3)
P 		1325.8
(-2.6)
P 		916
C 1317.5
(-1.5)
P 		2019.6
(3)
P 		1991.9
(2.8)
P 		1075.1
(-3)
P 		945
avr 1347.3
(-1.8) 		1944.8
(1.9) 		2123.6
(3) 		1156.3
(-3) 		967

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1655
1 2 3 4 5 6 range
A 2061.4
(-2)
P 		1869.4
(-3)
P 		2248.4
(-1.1)
P 		3047.8
(3)
P 		2546.4
(0.4)
P 		1982.6
(-2.4)
P 		1178
B 1832.8
(-2)
P 		2021.2
(-1)
P 		2548.1
(1.8)
P 		2777.5
(3)
P 		2584.6
(2)
P 		1653.9
(-3)
P 		1124
C 1792.4
(-1.3)
P 		1804.8
(-1.3)
P 		2818.9
(3)
P 		2713.1
(2.6)
P 		2451.3
(1.5)
P 		1393.2
(-3)
P 		1426
avr 1895.5
(-1.9) 		1898.5
(-1.9) 		2538.5
(1.4) 		2846.1
(3) 		2527.4
(1.4) 		1676.6
(-3) 		1170
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 538
1 2 3 4 range
A 530
(2.4)
P 		395.1
(0.4)
P 		573.5
(3)
P 		156.4
(-3)
P 		417
B 404.6
(0.3)
P 		492.6
(2.6)
P 		506.3
(3)
P 		282.5
(-3)
P 		224
C 436.1
(-0)
P 		580.6
(1.7)
P 		694.2
(3)
P 		181.3
(-3)
P 		513
avr 456.9
(0.9) 		489.4
(1.4) 		591.3
(3) 		206.7
(-3) 		385

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 670
1 2 3 4 5 6 range
A 380
(-3)
P 		664.8
(1.3)
P 		489.7
(-1.3)
P 		773
(3)
P 		768.4
(2.9)
P 		482.7
(-1.4)
P 		393
B 637.7
(-2.7)
P 		672.8
(-2.2)
P 		618.8
(-3)
P 		735.7
(-1.4)
P 		1050.1
(3)
P 		616.7
(-3)
P 		433
C 664.4
(0.6)
P 		550.7
(-1.5)
P 		717.5
(1.6)
P 		545.6
(-1.5)
P 		793.2
(3)
P 		466.4
(-3)
P 		327
avr 560.7
(-2.3) 		629.4
(-1.2) 		608.7
(-1.5) 		684.8
(-0.2) 		870.6
(3) 		521.9
(-3) 		349
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193050_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7632
Sequence Type Exemplar sequence
Representative Public ID C28H8.4 NCBI
Target Description C28H8.4 /REP_DB=WormBase Gene ID /WP=CE01826 /TR=SW:Q09473 /GB=AAA62292.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=ER lumen protein retaining receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065881(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065881 NCBI Caenorhabditis elegans C28H8.4 (C28H8.4) mRNA, complete cds. 11/11 None
SNAP00000005434 ENSEMBL cdna:SNAP chromosome:CEL140:III:5907007:5908139:1 11/11 None
GENEFINDER00000005441 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:5907007:5908139:1 11/11 None
C28H8.4 ENSEMBL cdna:known chromosome:CEL140:III:5906998:5908372:1 gene:C28H8.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:5907005-5908138(+) 100.0 100.0
Public Domain and Genome References
Gene Title ER lumen protein retaining receptor
Ensembl C28H8.4
Entrez Gene 175833 Entrez gene
SwissProt Q09473 EMBL-EBI
WormBase CE01826 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:257104_AT ER lumen protein retaining receptor, putative / HDEL receptor, putative at
CANINE:1604311_AT similar to ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) cfa
CANINE:1583270_AT similar to ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) cfa
CANINE_2:CFA.10501.1.A1_AT similar to ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) cfa
CANINE_2:CFA.21594.1.S1_AT similar to ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) cfa
CANINE_2:CFA.21594.1.S1_S_AT similar to ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) cfa
HG-U133_PLUS_2:200700_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133A:200700_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133A_2:200700_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133_PLUS_2:200698_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133A_2:200698_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133A:200698_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HUGENEFL:M88458_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
U133_X3P:G8051609_3P_A_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
U133_X3P:HS.118778.0.S2_3P_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133_PLUS_2:200699_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133A_2:200699_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-FOCUS:200699_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133A:200699_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U95AV2:39080_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HU35KSUBC:RC_AA160363_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HU35KSUBD:RC_AA416664_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
U133_X3P:HS.269956.0.A1_3P_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
U133_X3P:HS.118778.0.S3_3P_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
U133_X3P:HS.118778.0.S3_3P_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133_PLUS_2:242725_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U133B:242725_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U95B:42745_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U95B:58381_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
HG-U95D:72201_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 hs
MU11KSUBB:MSA.24379.0_F_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MU11KSUBB:MSA.20611.0_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MU11KSUBB:MSA.10066.0_F_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MG-U74AV2:101922_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MG-U74AV2:162201_R_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MG-U74BV2:164891_I_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MOE430A:1417205_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MOUSE430A_2:1417205_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MOUSE430_2:1417205_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MOE430A:1417204_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MOUSE430A_2:1417204_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MOUSE430_2:1417204_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 mm
MU11KSUBA:AA048853_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, mRNA (cDNA clone MGC:6366 IMAGE:3496891) mm
MU19KSUBA:TC17256_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, mRNA (cDNA clone MGC:6366 IMAGE:3496891) mm
MU19KSUBB:TC26296_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, mRNA (cDNA clone MGC:6366 IMAGE:3496891) mm
MU19KSUBB:TC33286_F_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, mRNA (cDNA clone MGC:6366 IMAGE:3496891) mm
MU19KSUBB:TC33286_I_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, mRNA (cDNA clone MGC:6366 IMAGE:3496891) mm
RG-U34B:RC_AA850164_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (predicted) rn
RAE230A:1371780_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (predicted) rn
RAT230_2:1371780_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (predicted) rn
RAE230A:1377269_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (predicted) rn
RAT230_2:1377269_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4872 receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_498282 C28H8.4 [Caenorhabditis elegans] gb|AAA62292.1| Hypothetical protein C28H8.4 [Caenorhabditis elegans] sp|Q09473|ERD22_CAEEL Putative ER lumen protein retaining receptor C28H8.4 1.0E-102
blast CAE64357 Hypothetical protein CBG09044 [Caenorhabditis briggsae] 3.0E-96
blast CAE70531 Hypothetical protein CBG17162 [Caenorhabditis briggsae] 4.0E-75
Protein Domains
Database ID Description E-Value
Pfam IPR000133 EMBL-EBI ER lumen protein retaining receptor 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_498282.1 5 58-80,92-109,119-138,151-168,178-200
C28H8.4 5 58-80,92-109,119-138,151-168,178-200
SNAP00000005434 5 58-80,92-109,119-138,151-168,178-200
GENEFINDER00000005441 5 58-80,92-109,119-138,151-168,178-200
Sequence
Target Sequence 
>C. ELEGANS:193050_AT
cacttgcttgcgattatcatccttctgctcaaaatctggaagagcagatcgtgctccgga
atctctgcgcggtcgcagattctgttcgctctcgtgttcactgctcgatacttggatctt
ttctccacatacatttctttgtataacactacaatgaagatcaccttcctcgccgctacg
tacgccacagtgtatctgatgttcttcaaattccgctcaacttacatgcgcgagtcggat
accttccgtgtcgagcttctcatcgtcccagctgcgatcctcgctcttctcatcaatcac
gatttcgctccatttgagttgctctggactttttcgatctatttggaggctgtggccatt
cttccacaactcttccttctccagtctaccggttccgctgaggtcatcactgctcactac
ttgttcgctcttggctcctaccgcgctctctacattttcaactggatttaccgctactac
accgaggactatttcgatccaattgtcgttgttgccggaattgtacaaactgttctctac
gccgatttcttctatctttacgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACTTGCTTGCGATTATCATCCTTC 311 197 46 Antisense
CTCGTGTTCACTGCTCGATACTTGG 253 233 136 Antisense
GGATCTTTTCTCCACATACATTTCT 265 511 159 Antisense
CGCTACGTACGCCACAGTGTATCTG 420 253 219 Antisense
TCTTCAAATTCCGCTCAACTTACAT 5 615 248 Antisense
TACATGCGCGAGTCGGATACCTTCC 630 643 268 Antisense
GATTTCGCTCCATTTGAGTTGCTCT 111 429 346 Antisense
TTGCTCTGGACTTTTTCGATCTATT 398 701 364 Antisense
AACTGGATTTACCGCTACTACACCG 621 141 505 Antisense
TGTACAAACTGTTCTCTACGCCGAT 463 559 567 Antisense
ACGCCGATTTCTTCTATCTTTACGT 190 91 584 Antisense
Sequence Source Affymetrix Proprietary Database