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[193040_s_at] ubiquitin carboxyl-terminal hydrolase

Description F46E10.8 /REP_DB=WormBase Gene ID /WP=CE20818 /TR=Q9UAV3 /GB=AAD14718.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=ubiquitin carboxyl-terminal hydrolase
Cluster 6grp_highest_10_10 > 29      6grp_high1_10_10 > 92      4grp_highest_8_8 > 12      4grp_high_8_8 > 39      6grp_highest_nonorm > 63      6grp_total > 84      4grp_total > 32      6grp_highest_sub > 04_05      6grp_cgc > 87      6grp_high1_sub > 04_05      6grp_cgc_sub > 05      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 455
1 2 3 4 range
A 375.3
(-3)
P 		518.1
(-0.8)
P 		765.4
(3)
P 		716
(2.2)
P 		390
B 338
(-3)
P 		700.5
(3)
P 		692.7
(2.9)
P 		633.6
(1.9)
P 		363
C 310.7
(-3)
P 		716
(3)
P 		661.3
(2.2)
P 		618.1
(1.6)
P 		405
avr 341.3
(-3) 		644.9
(2) 		706.5
(3) 		655.9
(2.2) 		365

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 562
1 2 3 4 5 6 range
A 655.2
(0)
P 		492.6
(-2.9)
P 		484.6
(-3)
P 		724.6
(1.3)
P 		822.6
(3)
P 		631.6
(-0.4)
P 		338
B 340.5
(-3)
P 		462.5
(-1.3)
P 		442.6
(-1.6)
P 		771.3
(3)
P 		720
(2.3)
P 		538.3
(-0.2)
P 		431
C 405.2
(-3)
P 		526.9
(-1.5)
P 		556
(-1.2)
P 		902.8
(3)
P 		649.8
(-0.1)
P 		595.1
(-0.7)
P 		498
avr 467
(-3) 		494
(-2.5) 		494.4
(-2.5) 		799.6
(3) 		730.8
(1.8) 		588.3
(-0.8) 		333
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 128
1 2 3 4 range
A 136.6
(-1)
P 		112.5
(-2.5)
P 		200.1
(3)
P 		104.8
(-3)
P 		95
B 107.8
(-3)
P 		173
(3)
P 		160.5
(1.8)
P 		135
(-0.5)
P 		65
C 102.9
(-3)
P 		205.9
(1.8)
P 		230.5
(3)
P 		104.2
(-2.9)
P 		128
avr 115.8
(-2.9) 		163.8
(0.6) 		197
(3) 		114.7
(-3) 		82

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 187
1 2 3 4 5 6 range
A 120.8
(-2.4)
P 		175.2
(-0.1)
P 		105.5
(-3)
P 		183.8
(0.3)
P 		248.2
(3)
P 		153.8
(-1)
P 		143
B 118.5
(-2.6)
P 		153.9
(-1.5)
P 		107.5
(-3)
P 		204.3
(0.1)
P 		292.5
(3)
P 		200.7
(0)
P 		185
C 150.2
(-2.2)
P 		160.8
(-1.3)
P 		141.5
(-3)
P 		181.6
(0.5)
P 		210.3
(3)
P 		199.2
(2)
P 		69
avr 129.8
(-2.5) 		163.3
(-1) 		118.2
(-3) 		189.9
(0.3) 		250.3
(3) 		184.6
(0) 		132
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193040_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12367
Sequence Type Exemplar sequence
Representative Public ID F46E10.8 NCBI
Target Description F46E10.8 /REP_DB=WormBase Gene ID /WP=CE20818 /TR=Q9UAV3 /GB=AAD14718.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=ubiquitin carboxyl-terminal hydrolase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072253(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072253 NCBI Caenorhabditis elegans UBiquitin C-terminal Hydrolase (family 1) family member (ubh-1) (ubh-1) mRNA, complete cds. 11/11 None
SNAP00000002130 ENSEMBL cdna:SNAP chromosome:CEL140:V:6512624:6513861:-1 10/11 None
GENEFINDER00000002140 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6512624:6513982:-1 11/11 None
F46E10.8 ENSEMBL cdna:known chromosome:CEL140:V:6512548:6514003:-1 gene:F46E10.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6512623-6513982(-) 100.0 100.0
Public Domain and Genome References
Gene Title ubiquitin carboxyl-terminal hydrolase
Gene Symbol ubh-1
Ensembl F46E10.8
Entrez Gene 179039 Entrez gene
SwissProt Q9UAV3 EMBL-EBI
WormBase CE20818 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1584026_AT similar to ubiquitin carboxy-terminal hydrolase L1 cfa
CANINE:1583249_S_AT similar to ubiquitin carboxy-terminal hydrolase L1 cfa
CANINE_2:CFA.4489.1.S1_AT similar to ubiquitin carboxy-terminal hydrolase L1 cfa
CANINE_2:CFAAFFX.24337.1.S1_S_AT similar to ubiquitin carboxy-terminal hydrolase L1 cfa
HG-U133A:201387_S_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
HG-U133_PLUS_2:201387_S_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
HG-FOCUS:201387_S_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
HG-U133A_2:201387_S_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
HU35KSUBC:RC_C14092_F_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
HUGENEFL:X04741_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
U133_X3P:G4759283_3P_S_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
HG-U95AV2:36990_AT ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
U133_X3P:HS2.433347.1.A1_3P_AT Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
HG-U133_PLUS_2:1555834_AT Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) hs
MG-U74AV2:96244_AT ubiquitin carboxy-terminal hydrolase L1 mm
MOE430A:1448260_AT ubiquitin carboxy-terminal hydrolase L1 mm
MOUSE430A_2:1448260_AT ubiquitin carboxy-terminal hydrolase L1 mm
MOUSE430_2:1448260_AT ubiquitin carboxy-terminal hydrolase L1 mm
MU19KSUBB:TC26568_AT Ubiquitin carboxyl-terminal hydrolase PGP9.5 (Uch-L1) mm
MU19KSUBB:TC26568_G_AT Ubiquitin carboxyl-terminal hydrolase PGP9.5 (Uch-L1) mm
MU19KSUBB:TC33272_AT Ubiquitin carboxyl-terminal hydrolase PGP9.5 (Uch-L1) mm
RG-U34A:RC_AA859882_S_AT ubiquitin carboxy-terminal hydrolase L1 rn
RG-U34A:D10699_AT ubiquitin carboxy-terminal hydrolase L1 rn
RG-U34A:D10699_G_AT ubiquitin carboxy-terminal hydrolase L1 rn
RG-U34B:RC_AA924736_F_AT ubiquitin carboxy-terminal hydrolase L1 rn
RG-U34C:RC_AI235043_F_AT ubiquitin carboxy-terminal hydrolase L1 rn
RAE230A:1369977_AT ubiquitin carboxy-terminal hydrolase L1 rn
RAT230_2:1369977_AT ubiquitin carboxy-terminal hydrolase L1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6511 ubiquitin-dependent protein catabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4221 ubiquitin thiolesterase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAD14718 Ubiquitin c-terminal hydrolase (family 1) protein 1 [Caenorhabditis elegans] ref|NP_504654.1| UBiquitin C-terminal Hydrolase (family 1) family member (ubh-1) [Caenorhabditis elegans] 1.0E-121
blast CAE71896 Hypothetical protein CBG18954 [Caenorhabditis briggsae] 1.0E-107
blast AAD14718 Ubiquitin c-terminal hydrolase (family 1) protein 1 [Caenorhabditis elegans] ref|NP_504654.1| UBiquitin C-terminal Hydrolase (family 1) family member (ubh-1) [Caenorhabditis elegans] 7.0E-90
blast CAE71896 Hypothetical protein CBG18954 [Caenorhabditis briggsae] 4.0E-79
blast CAE71897 Hypothetical protein CBG18955 [Caenorhabditis briggsae] 2.0E-59
Protein Domains
Database ID Description E-Value
Pfam IPR001578 EMBL-EBI Peptidase C12, ubiquitin carboxyl-terminal hydrolase family 1 1.5E-100
Pfam IPR001578 EMBL-EBI Peptidase C12, ubiquitin carboxyl-terminal hydrolase family 1 6.1E-40
Pfam IPR001578 EMBL-EBI Peptidase C12, ubiquitin carboxyl-terminal hydrolase family 1 3.6E-26
Sequence
Target Sequence 
>C. ELEGANS:193040_S_AT
gaaaacctcagcacgcagttatcctatgcttcccggaatacaaaaaggttgacgagatta
tgaagccgatctacgagcaagcgaaagcagctgacgattcggtgttttttatgaaacaga
aaatctcgaatgcttgtggaacattcgctctcttccattccctcgctaatcttgaagatc
gtattaatctaggggacggctcgtttgcgaaatggctggccgaggcgaaaaaggttggaa
ttgaggaacgttcggattttctagctaataatgctgagctagctggaatccatgctgccg
cagcaaccgatgggcagacagcaccttcaggagacgttgagcatcatttcatttgtttcg
tcggaaagaatggaattctctacgagatcgattctcgccgcccgttcgctcgtgaaatcg
gtccaacttctgatgcaactctcgtcaaggacgccggagctgcgtgccaacatctcattg
agaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAAACCTCAGCACGCAGTTATCCT 277 353 134 Antisense
AGTTATCCTATGCTTCCCGGAATAC 210 21 150 Antisense
TTGTGGAACATTCGCTCTCTTCCAT 282 709 267 Antisense
TCCATTCCCTCGCTAATCTTGAAGA 615 591 287 Antisense
GGGACGGCTCGTTTGCGAAATGGCT 24 493 326 Antisense
AGCTAGCTGGAATCCATGCTGCCGC 588 77 410 Antisense
GCAGACAGCACCTTCAGGAGACGTT 47 313 447 Antisense
CCCGTTCGCTCGTGAAATCGGTCCA 256 261 534 Antisense
AATCGGTCCAACTTCTGATGCAACT 50 169 549 Antisense
TGATGCAACTCTCGTCAAGGACGCC 120 567 564 Antisense
CTGCGTGCCAACATCTCATTGAGAA 456 237 593 Antisense
Sequence Source Affymetrix Proprietary Database