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[193024_at] NAD(P) transhydrogenase, mitochondrial

Description C15H9.1 /REP_DB=WormBase Gene ID /WP=CE08176 /TR=Q18031 /GB=AAB52670.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=NAD(P) transhydrogenase, mitochondrial
Cluster 6grp_highest_10_10 > 37      6grp_high1_10_10 > 62      4grp_highest_8_8 > 44      4grp_high_8_8 > 08      6grp_highest_nonorm > 44      6grp_total > 63      4grp_total > 31      6grp_highest_sub > 03_04      6grp_cgc > 75      6grp_high1_sub > 03      6grp_cgc_sub > 03_04      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 515
1 2 3 4 range
A 825.8
(3)
P 		332
(-3)
P 		425.9
(-1.9)
P 		530
(-0.6)
P 		494
B 791.6
(3)
P 		465.8
(-3)
P 		482
(-2.7)
P 		569.6
(-1.1)
P 		326
C 749.5
(3)
P 		311.3
(-3)
P 		431.3
(-1.4)
P 		719.8
(2.6)
P 		438
avr 789
(3) 		369.7
(-3) 		446.4
(-1.9) 		606.5
(0.4) 		419

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2652
1 2 3 4 5 6 range
A 754.2
(-3)
P 		1770.1
(-0.4)
P 		2146.4
(0.6)
P 		3065.6
(3)
P 		1660
(-0.6)
P 		1783.3
(-0.3)
P 		2311
B 948.8
(-3)
P 		1466.2
(-1.1)
P 		2589.9
(2.9)
P 		2605.5
(3)
P 		1497.6
(-1)
P 		1355.7
(-1.5)
P 		1657
C 1079.2
(-3)
P 		1425.3
(-2.1)
P 		3405.8
(3)
P 		2471.7
(0.6)
P 		1856
(-1)
P 		1435.2
(-2.1)
P 		2327
avr 927.4
(-3) 		1553.9
(-0.9) 		2714
(3) 		2714.3
(3) 		1671.2
(-0.5) 		1524.7
(-1) 		1787
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 229
1 2 3 4 range
A 300.7
(3)
P 		72.1
(-3)
P 		111.4
(-2)
P 		77.6
(-2.9)
P 		229
B 252.4
(3)
P 		115
(-2.9)
P 		111.7
(-3)
P 		121.4
(-2.6)
P 		141
C 248.1
(3)
P 		89.5
(-3)
P 		150.3
(-0.7)
P 		121.4
(-1.8)
P 		159
avr 267.1
(3) 		92.2
(-3) 		124.5
(-1.9) 		106.8
(-2.5) 		175

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 728
1 2 3 4 5 6 range
A 139
(-3)
P 		629.5
(1.6)
P 		467.4
(0.1)
P 		777.5
(3)
P 		500.9
(0.4)
P 		434.2
(-0.2)
P 		639
B 330.1
(-3)
P 		488
(-0.4)
P 		628.9
(2)
P 		690.1
(3)
P 		608.4
(1.6)
P 		505.5
(-0.1)
P 		360
C 400
(-3)
P 		434.9
(-2.6)
P 		866.8
(3)
P 		497.1
(-1.8)
P 		600.6
(-0.4)
P 		480.5
(-2)
P 		467
avr 289.7
(-3) 		517.5
(0.7) 		654.4
(3) 		654.9
(3) 		570
(1.6) 		473.4
(0) 		365
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193024_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17177
Sequence Type Exemplar sequence
Representative Public ID C15H9.1 NCBI
Target Description C15H9.1 /REP_DB=WormBase Gene ID /WP=CE08176 /TR=Q18031 /GB=AAB52670.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=NAD(P) transhydrogenase, mitochondrial
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076627(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076627 NCBI Caenorhabditis elegans Nicotinamide Nucleotide Transhydrogenase family member (nnt-1) (nnt-1) mRNA, complete cds. 11/11 None
SNAP00000042806 ENSEMBL cdna:SNAP chromosome:CEL140:X:6122280:6127408:1 11/11 None
GENEFINDER00000042815 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6122280:6127408:1 11/11 None
C15H9.1 ENSEMBL cdna:known chromosome:CEL140:X:6122273:6127499:1 gene:C15H9.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6122279-6127408(+) 100.0 100.0
Public Domain and Genome References
Gene Title NAD(P) transhydrogenase, mitochondrial
Gene Symbol nnt-1
Ensembl C15H9.1
Entrez Gene 180884 Entrez gene
SwissProt Q18031 EMBL-EBI
WormBase CE08176 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1604355_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CANINE:1599214_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CANINE:1590675_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CANINE_2:CFA.15220.1.A1_S_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CANINE_2:CFA.15220.2.A1_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CANINE_2:CFA.17697.1.S1_S_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CANINE_2:CFA.377.1.S1_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CANINE_2:CFAAFFX.28360.1.S1_S_AT similar to NAD(P) transhydrogenase, mitochondrial precursor (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase) cfa
CHICKEN:GGAAFFX.9445.1.S1_S_AT similar to nicotinamide nucleotide transhydrogenase gga
HG-FOCUS:202783_AT nicotinamide nucleotide transhydrogenase hs
HG-U133A:202783_AT nicotinamide nucleotide transhydrogenase hs
HG-U133_PLUS_2:202783_AT nicotinamide nucleotide transhydrogenase hs
HG-U133A_2:202783_AT nicotinamide nucleotide transhydrogenase hs
HU35KSUBC:RC_C14963_S_AT nicotinamide nucleotide transhydrogenase hs
HU35KSUBC:RC_AA258322_S_AT nicotinamide nucleotide transhydrogenase hs
HUGENEFL:U40490_AT nicotinamide nucleotide transhydrogenase hs
HG-U133A:202784_S_AT nicotinamide nucleotide transhydrogenase hs
HG-U133_PLUS_2:202784_S_AT nicotinamide nucleotide transhydrogenase hs
HG-U133A_2:202784_S_AT nicotinamide nucleotide transhydrogenase hs
U133_X3P:G6912535_3P_A_AT nicotinamide nucleotide transhydrogenase hs
U133_X3P:G1110519_3P_X_AT nicotinamide nucleotide transhydrogenase hs
U133_X3P:G1110519_3P_AT nicotinamide nucleotide transhydrogenase hs
U133_X3P:HS.95793.0.S1_3P_AT nicotinamide nucleotide transhydrogenase hs
HG-U133_PLUS_2:238530_AT nicotinamide nucleotide transhydrogenase hs
HG-U133B:238530_AT nicotinamide nucleotide transhydrogenase hs
HG-U95AV2:41722_AT nicotinamide nucleotide transhydrogenase hs
HG-U133_PLUS_2:215278_AT Nicotinamide nucleotide transhydrogenase hs
HG-U133A_2:215278_AT Nicotinamide nucleotide transhydrogenase hs
HG-U133A:215278_AT Nicotinamide nucleotide transhydrogenase hs
HU35KSUBD:RC_R16231_AT Nicotinamide nucleotide transhydrogenase hs
U133_X3P:HS.106620.0.S1_3P_AT Nicotinamide nucleotide transhydrogenase hs
HG-U95AV2:34441_AT Nicotinamide nucleotide transhydrogenase hs
HG-U133_PLUS_2:244531_AT Nicotinamide nucleotide transhydrogenase hs
HG-U133B:244531_AT Nicotinamide nucleotide transhydrogenase hs
HG-U95B:56726_R_AT Nicotinamide nucleotide transhydrogenase hs
HU35KSUBC:RC_AA136612_AT Nicotinamide nucleotide transhydrogenase hs
U133_X3P:HS.257274.0.A1_3P_AT Nicotinamide nucleotide transhydrogenase hs
MOUSE430_2:1432608_AT nicotinamide nucleotide transhydrogenase mm
MOE430B:1432608_AT nicotinamide nucleotide transhydrogenase mm
MOUSE430A_2:1456573_X_AT nicotinamide nucleotide transhydrogenase mm
MOE430A:1456573_X_AT nicotinamide nucleotide transhydrogenase mm
MOUSE430_2:1456573_X_AT nicotinamide nucleotide transhydrogenase mm
MU11KSUBB:Z49204_S_AT nicotinamide nucleotide transhydrogenase mm
MG-U74AV2:99009_AT nicotinamide nucleotide transhydrogenase mm
MOE430A:1416105_AT nicotinamide nucleotide transhydrogenase mm
MOUSE430A_2:1416105_AT nicotinamide nucleotide transhydrogenase mm
MOUSE430_2:1416105_AT nicotinamide nucleotide transhydrogenase mm
MU19KSUBC:TC36347_S_AT Nicotinamide nucleotide transhydrogenase, mRNA (cDNA clone MGC:6038 IMAGE:3601702) mm
RG-U34A:RC_AA891872_AT nicotinamide nucleotide transhydrogenase rn
RAE230A:1371483_AT nicotinamide nucleotide transhydrogenase rn
RAT230_2:1371483_AT nicotinamide nucleotide transhydrogenase rn
RAE230B:1381261_AT Nicotinamide nucleotide transhydrogenase rn
RAT230_2:1381261_AT Nicotinamide nucleotide transhydrogenase rn
RG-U34B:RC_AA955763_AT Nicotinamide nucleotide transhydrogenase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
15992 proton transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8746 NAD(P) transhydrogenase activity inferred from electronic annotation QuickGO AmiGO
8750 NAD(P)+ transhydrogenase (AB-specific) activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52670 Nicotinamide nucleotide transhydrogenase protein 1 [Caenorhabditis elegans] ref|NP_509028.1| Nicotinamide Nucleotide Transhydrogenase family member (nnt-1) [Caenorhabditis elegans] 0.0
blast CAE68875 Hypothetical protein CBG14838 [Caenorhabditis briggsae] 0.0
blast XP_799127 PREDICTED: similar to nicotinamide nucleotide transhydrogenase [Strongylocentrotus purpuratus] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR007698 EMBL-EBI Alanine dehydrogenase/PNT, C-terminal 1.3E-117
Pfam IPR007886 EMBL-EBI Alanine dehydrogenase/PNT, N-terminal 3.3E-77
Pfam IPR004003 EMBL-EBI NAD(P) transhydrogenase, beta subunit 1.0E-126
Pfam IPR004003 EMBL-EBI NAD(P) transhydrogenase, beta subunit 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509028.1 10 509-531,551-573,577-594,601-623,627-649,656-678,693-715,735-757,772-794,807-829
C15H9.1 10 509-531,551-573,577-594,601-623,627-649,656-678,693-715,735-757,772-794,807-829
SNAP00000042806 10 510-532,545-567,571-590,597-619,623-645,652-674,689-711,731-753,768-790,803-825
GENEFINDER00000042815 10 509-531,551-573,577-594,601-623,627-649,656-678,693-715,735-757,772-794,807-829
Sequence
Target Sequence 
>C. ELEGANS:193024_AT
gaaccgctctcttctaaatgtgatcttgggaggagttggaaccaagtcaaaaggaaccgg
tgaagcaaaagcaattgaggggactgcaaaagaaattgcaccagtagaaactgctgacat
gcttctcaatgctcgttcagtcatcatcattcctggatatggtctgtgtgcagctcaggc
acaatatcccatcgctcaacttgtcaaagaattgcaacagagaggtgttcgtgtcagatt
tgcaattcatccagttgcaggaagaatgccgggccagttgaacgtgcttcttgcggaagc
aggagtgccatatgatattgtggaagaaatggaagaaataaatgaagacttcaaagaaac
cgatgttgcacttgtgattggttcgaatgataccatcaattcagcggcggaagatgatcc
gaatagttcgattgcaggaatgcccgtgttgcgtgtctggaattcgaagcaggtcattat
cgtaaaaagaacactcggaaccggttacgctgcagtcgacaatcccgtgttctttaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACCGCTCTCTTCTAAATGTGATC 336 347 2520 Antisense
TGACATGCTTCTCAATGCTCGTTCA 643 569 2634 Antisense
CTCGTTCAGTCATCATCATTCCTGG 205 233 2651 Antisense
GATATGGTCTGTGTGCAGCTCAGGC 285 425 2675 Antisense
GTTGCAGGAAGAATGCCGGGCCAGT 22 439 2773 Antisense
CCAGTTGAACGTGCTTCTTGCGGAA 214 271 2793 Antisense
GAAACCGATGTTGCACTTGTGATTG 647 357 2875 Antisense
GATACCATCAATTCAGCGGCGGAAG 421 425 2908 Antisense
GATTGCAGGAATGCCCGTGTTGCGT 443 433 2949 Antisense
GAACACTCGGAACCGGTTACGCTGC 26 315 3008 Antisense
AGTCGACAATCCCGTGTTCTTTAAT 176 61 3033 Antisense
Sequence Source Affymetrix Proprietary Database