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[193009_at] 4-hydroxyphenylpyruvate dioxygenase

Description T21C12.2 /REP_DB=WormBase Gene ID /WP=CE02347 /TR=SW:Q22633 /GB=CAA90315.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=4-hydroxyphenylpyruvate dioxygenase
Cluster 6grp_highest_10_10 > 14      6grp_high1_10_10 > 41      4grp_highest_8_8 > 42      4grp_high_8_8 > 48      6grp_highest_nonorm > 15      6grp_total > 41      4grp_total > 63      6grp_cgc > 81      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2487
1 2 3 4 range
A 5270.8
(3)
P 		3358.2
(-2.4)
P 		4308.9
(0.3)
P 		3158.6
(-3)
P 		2112
B 5212.9
(3)
P 		3730.7
(-0.8)
P 		3911.2
(-0.4)
P 		2896.9
(-3)
P 		2316
C 5384.2
(3)
P 		3882.7
(-0.7)
P 		4189.5
(0.1)
P 		2923.9
(-3)
P 		2460
avr 5289.3
(3) 		3657.2
(-1.3) 		4136.5
(-0) 		2993.1
(-3) 		2296

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6751
1 2 3 4 5 6 range
A 4887.4
(0.6)
P 		5337
(1.2)
P 		6791.2
(3)
P 		4787.7
(0.5)
P 		3092
(-1.6)
P 		1986
(-3)
P 		4805
B 4770.9
(-0.6)
P 		4905.8
(-0.5)
P 		8736.7
(3)
P 		5091.8
(-0.3)
P 		3140.6
(-2.1)
P 		2180.1
(-3)
P 		6557
C 5012.4
(1.3)
P 		5188.1
(1.6)
P 		6108
(3)
P 		5890.5
(2.7)
P 		2882
(-2)
P 		2218.6
(-3)
P 		3889
avr 4890.2
(0.3) 		5143.6
(0.6) 		7212
(3) 		5256.7
(0.7) 		3038.2
(-1.9) 		2128.2
(-3) 		5084
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1457
1 2 3 4 range
A 1919.1
(3)
P 		729
(-1.9)
P 		1126.4
(-0.3)
P 		462.4
(-3)
P 		1457
B 1662.3
(3)
P 		921.4
(-1.3)
P 		906.3
(-1.3)
P 		617.3
(-3)
P 		1045
C 1782.3
(3)
P 		1116.3
(-0.1)
P 		1460.2
(1.5)
P 		493
(-3)
P 		1289
avr 1787.9
(3) 		922.2
(-1.1) 		1164.3
(0) 		524.2
(-3) 		1264

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1638
1 2 3 4 5 6 range
A 901
(-1.2)
P 		1898.1
(3)
P 		1479
(1.2)
P 		1214.3
(0.1)
P 		933
(-1.1)
P 		483.5
(-3)
P 		1415
B 1660
(0.9)
P 		1632.9
(0.8)
P 		2121.5
(3)
P 		1348.6
(-0.5)
P 		1276
(-0.9)
P 		812.9
(-3)
P 		1309
C 1857.9
(3)
P 		1583.1
(1.5)
P 		1554.6
(1.4)
P 		1184.6
(-0.6)
P 		932.6
(-2)
P 		742.7
(-3)
P 		1115
avr 1473
(1.6) 		1704.7
(2.9) 		1718.4
(3) 		1249.2
(0.3) 		1047.2
(-0.9) 		679.7
(-3) 		1039
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193009_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7306
Sequence Type Exemplar sequence
Representative Public ID T21C12.2 NCBI
Target Description T21C12.2 /REP_DB=WormBase Gene ID /WP=CE02347 /TR=SW:Q22633 /GB=CAA90315.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=4-hydroxyphenylpyruvate dioxygenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066923(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066923 NCBI Caenorhabditis elegans 4-HydroxyPhenylpyruvate Dioxygenase (HPD) family member (hpd-1) (hpd-1) mRNA, complete cds. 11/11 None
SNAP00000038800 ENSEMBL cdna:SNAP chromosome:CEL140:III:10534193:10537382:1 11/11 None
GENEFINDER00000038808 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10535427:10537382:1 11/11 None
T21C12.2.2 ENSEMBL cdna:known chromosome:CEL140:III:10535403:10537535:1 gene:T21C12.2 11/11 None
T21C12.2.1 ENSEMBL cdna:known chromosome:CEL140:III:10535405:10537553:1 gene:T21C12.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10535422-10537378(+) 100.0 100.0
Public Domain and Genome References
Gene Title 4-hydroxyphenylpyruvate dioxygenase
Gene Symbol hpd-1
Ensembl T21C12.2
Entrez Gene 176473 Entrez gene
SwissProt Q22633 EMBL-EBI
WormBase CE02347 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:262635_AT 4-hydroxyphenylpyruvate dioxygenase (HPD) at
ATGENOME1:15669_S_AT 4-hydroxyphenylpyruvate dioxygenase (HPD) at
CANINE_2:CFA.17539.1.S1_S_AT similar to 4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) cfa
CANINE_2:CFAAFFX.12947.1.S1_S_AT similar to 4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) cfa
DROSOPHILA_2:1637229_A_AT dm
DROSGENOME1:151899_AT dm
CHICKEN:GGA.1573.1.S1_AT similar to 4-hydroxyphenylpyruvate dioxygenase gga
HG-U133A:206024_AT 4-hydroxyphenylpyruvate dioxygenase hs
HG-U133_PLUS_2:206024_AT 4-hydroxyphenylpyruvate dioxygenase hs
HG-FOCUS:206024_AT 4-hydroxyphenylpyruvate dioxygenase hs
HG-U133A_2:206024_AT 4-hydroxyphenylpyruvate dioxygenase hs
HU35KSUBB:RC_AA010605_S_AT 4-hydroxyphenylpyruvate dioxygenase hs
HUGENEFL:D31628_S_AT 4-hydroxyphenylpyruvate dioxygenase hs
U133_X3P:G4504476_3P_AT 4-hydroxyphenylpyruvate dioxygenase hs
HG-U95AV2:33487_AT 4-hydroxyphenylpyruvate dioxygenase hs
HG-U95B:50649_S_AT 4-hydroxyphenylpyruvate dioxygenase hs
MOE430A:1424618_AT 4-hydroxyphenylpyruvic acid dioxygenase mm
MOUSE430A_2:1424618_AT 4-hydroxyphenylpyruvic acid dioxygenase mm
MOUSE430_2:1424618_AT 4-hydroxyphenylpyruvic acid dioxygenase mm
MU11KSUBA:D29987_S_AT 4-hydroxyphenylpyruvic acid dioxygenase mm
MG-U74AV2:100620_AT 4-hydroxyphenylpyruvic acid dioxygenase mm
MU19KSUBA:TC20378_F_AT 4-hydroxyphenylpyruvic acid dioxygenase, mRNA (cDNA clone MGC:14040 IMAGE:4193670) mm
MU19KSUBA:TC20378_R_AT 4-hydroxyphenylpyruvic acid dioxygenase, mRNA (cDNA clone MGC:14040 IMAGE:4193670) mm
RG-U34A:RC_AA866302_G_AT 4-hydroxyphenylpyruvic acid dioxygenase rn
RG-U34A:RC_AA866302_AT 4-hydroxyphenylpyruvic acid dioxygenase rn
RG-U34A:AF082834_S_AT 4-hydroxyphenylpyruvic acid dioxygenase rn
RAE230A:1368188_AT 4-hydroxyphenylpyruvic acid dioxygenase rn
RAT230_2:1368188_AT 4-hydroxyphenylpyruvic acid dioxygenase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
9072 aromatic amino acid family metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3868 4-hydroxyphenylpyruvate dioxygenase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90315 Hypothetical protein T21C12.2 [Caenorhabditis elegans] ref|NP_499324.1| 4-HydroxyPhenylpyruvate Dioxygenase (HPD) family member (hpd-1) [Caenorhabditis elegans] sp|Q22633|HPPD_CAEEL 4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) 0.0
blast CAE71449 Hypothetical protein CBG18361 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR004360 EMBL-EBI Glyoxalase/Bleomycin resistance protein/dioxygenase domain 1.2E-5
Pfam IPR004360 EMBL-EBI Glyoxalase/Bleomycin resistance protein/dioxygenase domain 7.8E-17
Pfam IPR004360 EMBL-EBI Glyoxalase/Bleomycin resistance protein/dioxygenase domain 1.2E-5
Pfam IPR004360 EMBL-EBI Glyoxalase/Bleomycin resistance protein/dioxygenase domain 7.8E-17
Sequence
Target Sequence 
>C. ELEGANS:193009_AT
tggactcagctgttcagtggtacgagaaggtgctgaaattccatcgattctggtctgttg
atgattccatgattcataccgagtactcggctcttcgttccattgttgtaacgaatttcg
aggagactattaagatgccaatcaacgagccagccacatcggacaaaaaggcaatctccc
aaatccaggaatacgtggattattacggaggatccggtgttcaacacatcgcactcaaca
catccgacatcattactgcaattgaagctcttcgagcccgtggctgtgaattcctttcca
ttccatcaagctactacgataacctcaaggaacgtctcgcggcttcttcaatggtagtta
aggaggatatggatcgtcttcagaagttgcacattttggtggatttcgatgagaatgggt
atttgctccaaatcttcagtaagccatgccaggaccgtccgacactattcttggagat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGGACTCAGCTGTTCAGTGGTACGA 219 549 587 Antisense
ATACCGAGTACTCGGCTCTTCGTTC 515 19 662 Antisense
AAAAAGGCAATCTCCCAAATCCAGG 673 127 751 Antisense
GGATCCGGTGTTCAACACATCGCAC 455 513 796 Antisense
AACACATCCGACATCATTACTGCAA 242 135 823 Antisense
TCGAGCCCGTGGCTGTGAATTCCTT 564 601 858 Antisense
TTTCCATTCCATCAAGCTACTACGA 222 665 881 Antisense
GATAACCTCAAGGAACGTCTCGCGG 342 421 904 Antisense
TCGCGGCTTCTTCAATGGTAGTTAA 502 597 923 Antisense
TTCAGTAAGCCATGCCAGGACCGTC 157 687 1021 Antisense
ACCGTCCGACACTATTCTTGGAGAT 391 89 1040 Antisense
Sequence Source Affymetrix Proprietary Database