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[192980_s_at] potassium channel protein

Description C30D11.1 /REP_DB=WormBase Gene ID /WP=CE27805 /GEN=unc-103 /TR=Q18325 /GB=CAA84644.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster 6grp_total > 15      4grp_total > 12      6grp_cgc > 23      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 93
1 2 3 4 range
A 34.1
(-1.1)
A 		13.8
(-2.4)
A 		4.8
(-3)
A 		97.5
(3)
P 		93
B 32.3
(1.8)
A 		38.7
(3)
A 		6.8
(-3)
A 		23.3
(0.1)
A 		32
C 29.6
(-0.7)
A 		11.3
(-2.6)
A 		7.2
(-3)
A 		65
(3)
A 		58
avr 32
(-0.2) 		21.3
(-1.4) 		6.3
(-3) 		61.9
(3) 		56

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 54
1 2 3 4 5 6 range
A 5.3
(-2)
A 		3.6
(-3)
A 		13.5
(3)
A 		8.2
(-0.2)
A 		4.1
(-2.7)
A 		3.9
(-2.8)
A 		10
B 41.3
(3)
A 		6.4
(-2.5)
A 		3.2
(-3)
A 		5.7
(-2.6)
A 		5.2
(-2.7)
A 		4.2
(-2.8)
A 		38
C 17.5
(-1.3)
A 		55.6
(3)
A 		3.9
(-2.8)
A 		17.7
(-1.2)
A 		2
(-3)
A 		7.6
(-2.4)
A 		54
avr 21.4
(2.8) 		21.9
(3) 		6.9
(-2) 		10.5
(-0.8) 		3.8
(-3) 		5.2
(-2.5) 		18
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 12.4
(2.1)
A 		3
(-2.2)
A 		1.3
(-3)
A 		14.3
(3)
P 		13
B 10.3
(3)
A 		9.6
(2.5)
A 		1.6
(-3)
A 		5
(-0.7)
A 		9
C 9.8
(2.2)
A 		3.3
(-2.4)
A 		2.5
(-3)
A 		11
(3)
A 		9
avr 10.8
(3) 		5.3
(-0.7) 		1.8
(-3) 		10.1
(2.5) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 1
(-2.7)
A 		1.3
(-1.8)
A 		2.9
(3)
A 		2.1
(0.6)
A 		1.2
(-2.1)
A 		0.9
(-3)
A 		2
B 14.4
(3)
A 		2.1
(-2.4)
A 		0.8
(-3)
A 		1.5
(-2.7)
A 		2.1
(-2.4)
A 		1.6
(-2.6)
A 		14
C 6.5
(-0.9)
A 		17
(3)
A 		1
(-2.9)
A 		3.6
(-1.9)
A 		0.7
(-3)
A 		2.5
(-2.3)
A 		16
avr 7.3
(3) 		6.8
(2.5) 		1.6
(-2.7) 		2.4
(-1.9) 		1.3
(-3) 		1.7
(-2.6) 		6
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192980_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7312
Sequence Type Exemplar sequence
Representative Public ID C30D11.1 NCBI
Target Description C30D11.1 /REP_DB=WormBase Gene ID /WP=CE27805 /GEN=unc-103 /TR=Q18325 /GB=CAA84644.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065423(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065423 NCBI Caenorhabditis elegans UNCoordinated family member (unc-103) (unc-103) mRNA, complete cds. 11/11 A 
C30D11.1 ENSEMBL cdna:known chromosome:CEL140:III:4138683:4147226:1 gene:C30D11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4138682-4142649(+) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel protein
Gene Symbol unc-103
Ensembl C30D11.1
Entrez Gene 175527 Entrez gene
SwissProt Q18325 EMBL-EBI
WormBase CE27805 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.20108.1.S1_S_AT similar to potassium voltage-gated channel, subfamily H, member 6 isoform 1 cfa
DROSOPHILA_2:1629418_S_AT seizure dm
DROSGENOME1:152427_AT seizure dm
CHICKEN:GGA.13087.1.S1_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 gga
CHICKEN:GGA.248.1.S1_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 gga
CHICKEN:GGA.7592.1.S1_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 gga
HG-U133_PLUS_2:211045_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A:211045_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A_2:211045_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133_PLUS_2:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-FOCUS:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A_2:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133_PLUS_2:211046_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A:211046_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A_2:211046_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBA:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBB:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBC:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBD:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HUGENEFL:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HC-G110:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
U133_X3P:G13623462_3P_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
U133_X3P:G13540548_3P_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
U133_X3P:221023_3P_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U95D:86319_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
RN-U34:RC_AA894087_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
RG-U34A:RC_AA894087_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
RAE230A:1369017_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
RAT230_2:1369017_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAC42257 Hypothetical protein C30D11.1 [Caenorhabditis elegans] emb|CAA84644.2| Hypothetical protein C30D11.1 [Caenorhabditis elegans] ref|NP_497824.1| UNCoordinated family member (unc-103) [Caenorhabditis elegans] gb|AAF68999.1| HERG-like potassium channel [Caenorhabditis elegans] 0.0
blast CAE72879 Hypothetical protein CBG20190 [Caenorhabditis briggsae] 0.0
blast XP_393977 PREDICTED: similar to ENSANGP00000009272 [Apis mellifera] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 1.8E-33
Pfam IPR000595 EMBL-EBI Cyclic nucleotide-binding domain 3.1E-24
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497824.1 4 85-107,225-247,289-311,318-340
C30D11.1 4 85-107,225-247,289-311,318-340
Sequence
Target Sequence 
>C. ELEGANS:192980_S_AT
gtatcggcgacgacagactctgagaagatcttcacaattatcatgatgattctcggttct
ttgatgtacgcctctgtgttcggtaatgtatcggcgattattcagaggttgtactcggga
actgcaagatatcatacggagatgtcaaggctcagagaatttatccgatttcaccagatc
ccaaatcctctacgacaacgattagaggaatacttccaacatgcatggtcctacaccaac
ggaattgacatgaatttggttttgaaggggtttcccgactgccttcaagctgatatttgt
cttcatttgaataggaatctgttgagtggttgtgcagcatttgcaggcagcacacccgga
tgtctcagagcactttcgatgaggtttcgaacgacacattcaccgccgggagatactctg
gtacatcgtggagatattttaacgggattgtacttcatcgcgaga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTATCGGCGACGACAGACTCTGAGA 471 453 934 Antisense
ATTCTCGGTTCTTTGATGTACGCCT 659 7 982 Antisense
ACGCCTCTGTGTTCGGTAATGTATC 569 89 1001 Antisense
TTATCCGATTTCACCAGATCCCAAA 411 679 1094 Antisense
CTTCCAACATGCATGGTCCTACACC 275 219 1146 Antisense
CCGACTGCCTTCAAGCTGATATTTG 707 263 1208 Antisense
GTGCAGCATTTGCAGGCAGCACACC 288 479 1265 Antisense
ACACCCGGATGTCTCAGAGCACTTT 178 109 1285 Antisense
AGGTTTCGAACGACACATTCACCGC 567 57 1315 Antisense
TCACCGCCGGGAGATACTCTGGTAC 503 615 1333 Antisense
AACGGGATTGTACTTCATCGCGAGA 126 145 1374 Antisense
Sequence Source Affymetrix Proprietary Database